Balanol Analogues Probe Specificity Determinants and the Conformational Malleability of the Cyclic 3′,5′-Adenosine Monophosphate-Dependent Protein Kinase Catalytic Subunit

Biochemistry

Volumn 43, Issue 1, 2004, Pages 85-96

  Akamine, Pearl ^a,c   Madhusudan, ^a   Brunton, Laurence L ^b   Ou, Horng D ^d   Canaves, Jaume M ^a   Xuong, Nguyen Huu ^a   Taylor, Susan S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b San Diego   (United States)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST SELECTIVITY; CHEMICAL MODIFICATION; CONFORMATIONS; CRYSTAL STRUCTURE; DISEASE CONTROL; ENZYME INHIBITION; PROTEINS; THERMODYNAMIC STABILITY;

DENATURATION; HOMOLOGY; THERAPEUTICS;

BIOCHEMISTRY;

BALANOL; BALANOL ANALOG; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME INHIBITION; ENZYME PURIFICATION; ENZYME SUBUNIT; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; THERMOSTABILITY;

ESCHERICHIA COLI;

EID: 0346094142     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035042p     Document Type: Article

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