Regulation of hypoxia-inducible factor-1α by nitric oxide through mitochondria-dependent and -independent pathways

Biochemical Journal

Volumn 376, Issue 2, 2003, Pages 537-544

  Mateo, Jesús ^a   García Lecea, Marta ^a   Cadenas, Susana ^a   Hernández, Carlos ^a   Moncada, Salvador ^b  

^a CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Cytochrome c oxidase; Hypoxia; Hypoxia inducible factor 1 (HIF 1 ); Mitochondria; Nitric oxide (NO); Oxygen (O2)

Indexed keywords

DNA; ENZYMES; NITROGEN COMPOUNDS; RESPIRATORY MECHANICS;

TRANSCRIPTION FACTORS;

BIOCHEMISTRY;

CYTOCHROME C OXIDASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN; TETRACYCLINE;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME INHIBITION; ENZYME MECHANISM; GENE ACTIVITY; GENE CONTROL; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RESPIRATORY CHAIN;

CELL HYPOXIA; CELL LINE; CELL RESPIRATION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MITOCHONDRIA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OXYGEN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 0346027211     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20031155     Document Type: Article

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