Induction of the TNF-α Promoter in the Murine Dendritic Cell Line 18 and the Murine Mast Cell Line CPII Is Differently Regulated

Journal of Immunology

Volumn 157, Issue 6, 1996, Pages 2645-2653

  Prieschl, E E ^a   Pendl, G G ^a   Elbe, A ^b   Serfling, E ^c   Harrer, N E ^a   Stingl, G ^b   Baumruker, T ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b Universitatsklinik fur Dermatologie   (Austria)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL LINE; COMPARATIVE STUDY; DENDRITIC CELL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOLOGY; MAST CELL; METABOLISM; MOUSE; PROMOTER REGION; SIGNAL TRANSDUCTION;

ANIMALS; CELL LINE; DENDRITIC CELLS; GENE EXPRESSION REGULATION; HUMANS; MAST CELLS; MICE; PROMOTER REGIONS (GENETICS); SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030587128     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Burkly, L., C. Hession, L. Ogata, C. Reilly, L. A. Marconi, D. Olson, R. Tizard, R. Cate, and D. Lo. 1995. Expression of relB is required for the development of thymic medulla and dendritic cells. Nature 373:531.
2. Weih, F., D. Carrasco, S. K. Durham, D. Barton, C. A. Rizzo, R. P. Ryseck, S. A. Lira, and R. Bravo. 1995. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB/Rel family. Cell 80:331.
3. Carrasco, D., R. P. Ryseck, and R. Bravo. 1993. Expression of relB transcripts during lymphoid organ development-specific expression in dendritic antigen-presenting cells. Development 118:1221.
4. Thanos, D., and T. Maniatis. 1995. NF-κB: a lesson in family values. Cell 80: 529.
5. Baeuerle, P. A., and T. Henkel. 1994. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12:141.
6. Carrasco, D., F. Weih, and R. Bravo. 1994. Developmental expression of the mouse c-rel proto-oncogene in hematopoietic organs. Development 120:2991.
7. Lernbecher, T., B. Kistler, and T. Wirth. 1994. Two distinct mechanisms contribute to the constitutive activation of RelB in lymphoid cells. EMBO J. 13:4060.
8. Lernbecher, T., U. Müller, and T. Wirth. 1993. Distinct NF-κB/Rel transcription factors are responsible for tissue-specific and inducible gene activation. Nature 365:767.
9. + T cells. J. Immunol. 153:2878.
10. Kulmburg, P. A., N. E. Huber, B. J. Scheer, M. Wrann, and T. Baumruker. 1992. Immunoglobulin E plus artigen challenge induces a novel intercrine/chemokine in mouse mast cells. J. Exp. Med. 176:1773.
11. Jarmin, D. I., P. A. Kulmburg, N. E. Huber, G. Baumann, E. E. Prieschl-Strassmayr, and T. Baumruker. 1994. A transcription factor with AP3-like binding specificity meditates gene regulation after an allergic triggering with IgE and antigen in mouse mast cells. J. Immunol. 5720.
12. Prieschl, E. E., V. Gouilleux-Gruart, C. Walker, N. E. Harrer, and T. Baumruker. 1995. A nuclear factor of activated T cell-like transcription factor in mast cells is involved in IL-5 gene regulation after IgE plus Ag stimulation. J. Immunol. 154: 6112.
13. ras links FcRI to NF-AT family member in mast cells: the AP3-like factor in this cell type is an NF-AT family member. J. Immunol. 155:4963.
14. Kruys, V., K. Kemmer, A. Shakhov, V. Jongeneel, and B. Beutler. 1992. Constitutive activity of the tumor necrosis factor promoter is canceled by the 3′ untranslated region in monmacrophage cell lines: a trans-dominant factor overcomes this suppressive effect. Proc. Natl. Acad. Sci. USA 89:673.
15. Jain, J., P. G. McCaffrey, Z. Miner, T. K. Kerppola, J. N. Lambert, G. L. Verdine, T. Curran, and A. Rao. 1993. The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with fos and jun. Nature 365:352.
16. Liu, J., J. D. Farmer, Jr., W. S. Lane, J. Friedman, I. Weissman, and S. L. Schreiber. 1991. Calcineurin is a common target of cyclophillin-cyclosporin A and FKBP-FK506 complexes. Cell 66:807.
17. Fruman, D. A., C. B. Klee, B. E. Bierer, and S. J. Burakoff. 1992. Calcineurin phosphatase activity in T lymphocytes is inhibited by FK506 and CsA. Proc. Natl. Acad. Sci. USA 89:3686.
18. Fujita, T., G. P. Nolan, S. Ghosh, and D. Baltimore. 1992. Independent modes of transcriptional activation by the p50 and p65 subunits of NF-κB. Genes Dev. 6:775.
19. Beutler, B., and A. Cerami. 1989. The biology of cachectin/TNF-α primary mediator of the host response. Annu. Rev. Immunol. 7:625.
20. Vilcek, J., and T. H. Lee. 1991. Tumor necrosis factor. J. Biol Chem. 266:7311.
21. Beutler, B. 1992. Application of transcriptional and posttranscriptional reporter constructs to the analysis of tumor necrosis factor gene regulation. Am. J. Med. Sci. 303:129.
22. Gordon, J. R., and S. J. Galli. 1991. Release of both preformed and newly synthesized tumor necrosis factor a (TNFα)/cachectin by mouse mast cells stimulated via the FcR1: a mechanism for the sustained action of mast cell-derived TNFa during IgE-dependent biological responses. J. Exp. Med. 174:103.
23. Kuprash, D. V., I. A. Udalova, R. L. Turelskaya, N. R. Rice, and S. A. Nedospasov. 1995. Conserved kB element located downstream of the tumor necrosis factor a gene, distinct NF-κB binding pattern and enhanced activity in LPS-activated murine macrophages. Oncogene 11:97.
24. Trede, N. S., A. V. Tsytsykova, T. Chatila, A. E. Goldfeld, and R. S. Geha. 1995. Transcriptional activation of the human TNF-α promoter by superantigen in human monocytic cells: role of NF-κB. J. Immunol. 155:902.
25. Goldfeld, A. E., J. L. Strominger, and C. Doyle. 1991. Human tumor necrosis factor a gene regulation in phorbol ester stimulated T and B cell lines. J. Exp. Med. 174:73.
26. McCaffrey, P. G., A. E. Goldfeld, and A. Rao. 1994. The role of NFATp in cyclosporin A-sensitive tumor necrosis factor-alpha gene transcription. J. Biol. Chem. 269:30445.
27. Dekker, L. V., and P. J. Parker. 1994. Protein kinase C: a question of specificity. Trends Biochem. Sci. 19:73.
28. 2+-independent protein kinase Cs contain an ammo-terminal domain similar to the C2 consensus sequence. Trends Biochem. Sci. 18:207.
29. Rhoadest, K. L., S. H. Golub, and J. S. Economou. 1992. The regulation of the human tumor necrosis factor a promoter region in macrophage, T cell, and B cell lines. J. Biol. Chem. 267:22102.
30. Tsai, E. Y., J. Jain, P. A. Pesavento, A. Rao, and A. E. Goldfeld. 1996. Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NF-ATp. Mol. Cell. Biol. 16:459.
31. Ziegler-Heitbrock, H. W. L., T. Sternsdorf, J. Liese, B. Belohradsky, C. Weber, A. Wedel, R. Schreck, P. Baeuerle, and M. Ströbel. 1993. Pyrrolidine dithiocarbamate inhibits NF-κB mobilization and TNF production in human monocytes. J. Immunol. 151:6986.
32. Ueda, A., K. Okuda, S. Ohno, A. Shirai, T. Igarashi, K. Matsunaga, J. Fukushima, S. Kawamoto, Y. Ishigatsubo, and T. Okubo. 1994. NF-κB and SP1 regulate transcription of the human monocyte chemoattractant protein-1 gene. J. Immunol. 153:2052.
33. Perkins, N. D., A. B. Agranoff, E. Pascal, and G. J. Nabel. 1994. An interaction between the DNA-binding domains of RelA(p65) and Sp1 mediates human immundeficiency virus gene activation. Mol. Cell. Biol. 14:6570.
34. Li, Y., G. Mak, and R. B. Franza, Jr. 1994. In vitro study of functional involvement of Sp1, NF-κB/Rel, and AP1 in phorbol 12-myristate 13-acetate-mediated HIV-1 long terminal repeat activation. J. Biol. Chem. 269:30616.
35. Randak, C., T. Brabletz, M. Hergenröther, I. Sobotta, and E. Serfling. 1990. Cyclosporin A suppresses the expression of the interleukin 2 gene by inhibiting the binding of lymphocyte-specific factors to the IL-2 enhancer. EMBO J. 9:2529.
36. Pessara, U., and N. Koch. 1990. Tumor necrosis factor a regulates expression of the major histocompatibility complex class II-associated invariant chain by binding of an NF-κB-like factor to a promoter element. Mol. Cell. Biol. 10:4146.
37. Angel, P., M. Imagawa, R. Chiu, B. Stein, R. J. Imbra, H. J. Rahmsdorf, C. Jonat. P. Herrlich, and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49:729.