-
1
-
-
0036791010
-
Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1
-
Asher G, Lotem J, Kama R, Sachs L, Shaul Y: Mdm-2 and ubiquitin-independent p53 proteasomal degradation regulated by NQO1. Proc Natl Acad Sci USA 2002;99:13125-13130.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13125-13130
-
-
Asher, G.1
Lotem, J.2
Kama, R.3
Sachs, L.4
Shaul, Y.5
-
2
-
-
0031587821
-
Recruitment of p300/CBP in p53-dependent signal pathways
-
Avantaggiati ML, Ogryzko V, Gardner K, Giordano A, Levine AS, Kelly K: Recruitment of p300/CBP in p53-dependent signal pathways. Cell 1997;89:1175-1184.
-
(1997)
Cell
, vol.89
, pp. 1175-1184
-
-
Avantaggiati, M.L.1
Ogryzko, V.2
Gardner, K.3
Giordano, A.4
Levine, A.S.5
Kelly, K.6
-
3
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
Banin S, Moyal L, Shieh S, Taya Y, Anderson CW, Chessa L, Smorodinsky NI, Prives C, Reiss Y, Shiloh Y, Ziv Y: Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 1998;281:1674-1677.
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
Ziv, Y.11
-
4
-
-
0032407025
-
The t(8;21) translocation is not consistently associated with high Bcl-2 expression in de novo acute myeloid leukemias of adults
-
Banker DE, Radich J, Becker A, Kerkof K, Norwood T, Willman C, Appelbaum FR: The t(8;21) translocation is not consistently associated with high Bcl-2 expression in de novo acute myeloid leukemias of adults. Clin Cancer Res 1998;4:3051-3062.
-
(1998)
Clin Cancer Res
, vol.4
, pp. 3051-3062
-
-
Banker, D.E.1
Radich, J.2
Becker, A.3
Kerkof, K.4
Norwood, T.5
Willman, C.6
Appelbaum, F.R.7
-
5
-
-
0036668568
-
Cloning and characterization of an androgen receptor N-terminal- interacting protein with ubiquitin-protein ligase activity
-
Beitel LK, Elhaji YA, Lumbroso R, Wing SS, Panet-Raymond V, Gottlieb B, Pinsky L, Trifiro MA: Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity. J Mol Endocrinol 2002;29:41-60.
-
(2002)
J Mol Endocrinol
, vol.29
, pp. 41-60
-
-
Beitel, L.K.1
Elhaji, Y.A.2
Lumbroso, R.3
Wing, S.S.4
Panet-Raymond, V.5
Gottlieb, B.6
Pinsky, L.7
Trifiro, M.A.8
-
6
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
Canman CE, Lim DS, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, Appella E, Kastan MB, Siliciano JD: Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 1998;281:1677-1679.
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siliciano, J.D.9
-
8
-
-
0035281739
-
Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis
-
Christiansen DH, Andersen MK, Pedersen-Bjergaard J: Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis. J Clin Oncol 2001;19:1405-1413.
-
(2001)
J Clin Oncol
, vol.19
, pp. 1405-1413
-
-
Christiansen, D.H.1
Andersen, M.K.2
Pedersen-Bjergaard, J.3
-
9
-
-
0020333906
-
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia
-
De Klein A, van Kessel AG, Grosveld G, Bartram CR, Hagemeijer A, Bootsma D, Spurr NK, Heisterkamp N, Groffen J, Stephenson JR: A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukaemia. Nature 1982;300:765-767.
-
(1982)
Nature
, vol.300
, pp. 765-767
-
-
De Klein, A.1
Van Kessel, A.G.2
Grosveld, G.3
Bartram, C.R.4
Hagemeijer, A.5
Bootsma, D.6
Spurr, N.K.7
Heisterkamp, N.8
Groffen, J.9
Stephenson, J.R.10
-
10
-
-
0032831130
-
Mll rearrangements in haematological malignancies: Lessons from clinical and biological studies
-
Dimartino JF, Cleary ML: Mll rearrangements in haematological malignancies: Lessons from clinical and biological studies. Br J Haematol 1999;106:614-626.
-
(1999)
Br J Haematol
, vol.106
, pp. 614-626
-
-
Dimartino, J.F.1
Cleary, M.L.2
-
11
-
-
0032822953
-
The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: Biology and clinical significance
-
Downing JR: The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: Biology and clinical significance. Br J Haematol 1999; 106:296-308.
-
(1999)
Br J Haematol
, vol.106
, pp. 296-308
-
-
Downing, J.R.1
-
12
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B: WAF1, a potential mediator of p53 tumor suppression. Cell 1993; 75:817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
13
-
-
0032189081
-
Secondary leukemias induced by topoisomerase-targeted drugs
-
Felix CA: Secondary leukemias induced by topoisomerase-targeted drugs. Biochim Biophys Acta 1998;1400:233-255.
-
(1998)
Biochim Biophys Acta
, vol.1400
, pp. 233-255
-
-
Felix, C.A.1
-
14
-
-
0037041392
-
p63 and p73 are required for p53-dependent apoptosis in response to DNA damage
-
Flores ER, Tsai KY, Crowley D, Sengupta S, Yang A, McKeon F, Jacks T: p63 and p73 are required for p53-dependent apoptosis in response to DNA damage. Nature 2002;416: 560-564.
-
(2002)
Nature
, vol.416
, pp. 560-564
-
-
Flores, E.R.1
Tsai, K.Y.2
Crowley, D.3
Sengupta, S.4
Yang, A.5
McKeon, F.6
Jacks, T.7
-
15
-
-
0041450058
-
PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms
-
Freeman DJ, Li AG, Wei G, Li HH, Kertesz N, Lesche R, Whale AD, Martinez-Diaz H, Rozengurt N, Cardiff RD, Liu X, Wu H: PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms. Cancer Cell 2003;3:117-130.
-
(2003)
Cancer Cell
, vol.3
, pp. 117-130
-
-
Freeman, D.J.1
Li, A.G.2
Wei, G.3
Li, H.H.4
Kertesz, N.5
Lesche, R.6
Whale, A.D.7
Martinez-Diaz, H.8
Rozengurt, N.9
Cardiff, R.D.10
Liu, X.11
Wu, H.12
-
16
-
-
0032512057
-
MDM2 association with p53 targets its ubiquitination
-
Fuchs SY, Adler V, Buschmann T, Wu X, Ronai Z: MDM2 association with p53 targets its ubiquitination. Oncogene 1998;17:2543-2547.
-
(1998)
Oncogene
, vol.17
, pp. 2543-2547
-
-
Fuchs, S.Y.1
Adler, V.2
Buschmann, T.3
Wu, X.4
Ronai, Z.5
-
17
-
-
0035886865
-
Requirement for MDM2 in the survival effects of BCR-ABL and interleukin-3 in hematopoietic cells
-
Goetz AW, van der Kuip H, Maya R, Oren M, Aulitzky WE: Requirement for MDM2 in the survival effects of BCR-ABL and interleukin-3 in hematopoietic cells. Cancer Res 2001;61: 7635-7641.
-
(2001)
Cancer Res
, vol.61
, pp. 7635-7641
-
-
Goetz, A.W.1
Van Der Kuip, H.2
Maya, R.3
Oren, M.4
Aulitzky, W.E.5
-
18
-
-
0037432773
-
Polyubiquitination of p53 by a ubiquitin ligase activity of p300
-
Grossman SR, Deato ME, Brignone C, Chan HM, Kung AL, Tagami H, Nakatani Y, Livingston DM: Polyubiquitination of p53 by a ubiquitin ligase activity of p300. Science 2003;300:342-344.
-
(2003)
Science
, vol.300
, pp. 342-344
-
-
Grossman, S.R.1
Deato, M.E.2
Brignone, C.3
Chan, H.M.4
Kung, A.L.5
Tagami, H.6
Nakatani, Y.7
Livingston, D.M.8
-
19
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
Gu W, Roeder RG: Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 1997;90:595-606.
-
(1997)
Cell
, vol.90
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
21
-
-
0030905284
-
MDM2 promotes the rapid degradation of p53
-
Haupt Y, Maya R, Kazaz A, Oren M: MDM2 promotes the rapid degradation of p53. Nature 1997;387:296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
22
-
-
0031310665
-
14-3-3 sigma is a p53-regulated inhibitor of G2/M progression
-
Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, Thiagalingam S, Kinzler KW, Vogelstein B: 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Mol Cell 1997;1:3-11.
-
(1997)
Mol Cell
, vol.1
, pp. 3-11
-
-
Hermeking, H.1
Lengauer, C.2
Polyak, K.3
He, T.C.4
Zhang, L.5
Thiagalingam, S.6
Kinzler, K.W.7
Vogelstein, B.8
-
23
-
-
0034888197
-
Frequent loss of heterozygosity in the region of D1S450 at 1p36.2 in myelodysplastic syndromes
-
Hofmann WK, Takeuchi S, Xiw D, Miller CW, Hoelzer D, Koeffler HP: Frequent loss of heterozygosity in the region of D1S450 at 1p36.2 in myelodysplastic syndromes. Leuk Res 2001; 25:855-858.
-
(2001)
Leuk Res
, vol.25
, pp. 855-858
-
-
Hofmann, W.K.1
Takeuchi, S.2
Xiw, D.3
Miller, C.W.4
Hoelzer, D.5
Koeffler, H.P.6
-
24
-
-
0032520986
-
Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: A novel transgenic model for human Ph1-positive leukemias
-
Honda H, Oda H, Suzuki T, Takahashi T, Witte ON, Ozawa K, Ishikawa T, Yazaki Y, Hirai H: Development of acute lymphoblastic leukemia and myeloproliferative disorder in transgenic mice expressing p210bcr/abl: A novel transgenic model for human Ph1-positive leukemias. Blood 1998;91:2067-2075.
-
(1998)
Blood
, vol.91
, pp. 2067-2075
-
-
Honda, H.1
Oda, H.2
Suzuki, T.3
Takahashi, T.4
Witte, O.N.5
Ozawa, K.6
Ishikawa, T.7
Yazaki, Y.8
Hirai, H.9
-
25
-
-
0034651959
-
Acquired loss of p53 induces blastic transformation in p210 (bcr/abl)-expressing hematopoietic cells: A transgenic study for blast crisis of human CML
-
Honda H, Ushijima T, Wakazono K, Oda H, Tanaka Y, Aizawa S, Ishikawa T, Yazaki Y, Hirai H: Acquired loss of p53 induces blastic transformation in p210 (bcr/abl)-expressing hematopoietic cells: A transgenic study for blast crisis of human CML. Blood 2000;95:1144-1150.
-
(2000)
Blood
, vol.95
, pp. 1144-1150
-
-
Honda, H.1
Ushijima, T.2
Wakazono, K.3
Oda, H.4
Tanaka, Y.5
Aizawa, S.6
Ishikawa, T.7
Yazaki, Y.8
Hirai, H.9
-
26
-
-
0032868343
-
Distinct genetic involvement of the TP53 gene in therapy-related leukemia and myelodysplasia with chromosomal losses of Nos 5 and/or 7 and its possible relationship to replication error phenotype
-
Horiike S, Misawa S, Kaneko H, Sasai Y, Kobayashi M, Fujii H, Tanaka S, Yagita M, Abe T, Kashima K, Taniwaki M: Distinct genetic involvement of the TP53 gene in therapy-related leukemia and myelodysplasia with chromosomal losses of Nos 5 and/or 7 and its possible relationship to replication error phenotype. Leukemia 1999;13:1235-1242.
-
(1999)
Leukemia
, vol.13
, pp. 1235-1242
-
-
Horiike, S.1
Misawa, S.2
Kaneko, H.3
Sasai, Y.4
Kobayashi, M.5
Fujii, H.6
Tanaka, S.7
Yagita, M.8
Abe, T.9
Kashima, K.10
Taniwaki, M.11
-
27
-
-
0033179665
-
Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation
-
Kawano S, Miller CW, Gombart AF, Bartram CR, Matsuo Y, Asou H, Sakashita A, Said J, Tatsumi E, Koeffler HP: Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation. Blood 1999;94:1113-1120.
-
(1999)
Blood
, vol.94
, pp. 1113-1120
-
-
Kawano, S.1
Miller, C.W.2
Gombart, A.F.3
Bartram, C.R.4
Matsuo, Y.5
Asou, H.6
Sakashita, A.7
Said, J.8
Tatsumi, E.9
Koeffler, H.P.10
-
28
-
-
0028293945
-
The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion
-
Koken MH, Puvion-Dutilleul F, Guillemin MC, Viron A, Linares-Cruz G, Stuurman N, de Jong L, Szostecki C, Calvo F, Chomienne C et al: The t(15;17) translocation alters a nuclear body in a retinoic acid-reversible fashion. EMBO J 1994;13:1073-1083.
-
(1994)
EMBO J
, vol.13
, pp. 1073-1083
-
-
Koken, M.H.1
Puvion-Dutilleul, F.2
Guillemin, M.C.3
Viron, A.4
Linares-Cruz, G.5
Stuurman, N.6
De Jong, L.7
Szostecki, C.8
Calvo, F.9
Chomienne, C.10
-
29
-
-
0037071399
-
Tumor suppressor genes in normal and malignant hematopoiesis
-
Krug U, Ganser A, Koeffler HP: Tumor suppressor genes in normal and malignant hematopoiesis. Oncogene 2002;21:3475-3495.
-
(2002)
Oncogene
, vol.21
, pp. 3475-3495
-
-
Krug, U.1
Ganser, A.2
Koeffler, H.P.3
-
30
-
-
0030965946
-
Regulation of p53 stability by MDM2. Regulation of p53 stability by MDM2
-
Kubbutat MH, Jones SN, Vousden KH: Regulation of p53 stability by MDM2. Regulation of p53 stability by MDM2. Nature 1997;387:299-303.
-
(1997)
Nature
, vol.387
, pp. 299-303
-
-
Kubbutat, M.H.1
Jones, S.N.2
Vousden, K.H.3
-
31
-
-
0031014946
-
Proteolytic cleavage of human p53 by calpain: A potential regulator of protein stability
-
Kubbutat MH, Vousden KH: Proteolytic cleavage of human p53 by calpain: A potential regulator of protein stability. Mol Cell Biol 1997;17:460-468.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 460-468
-
-
Kubbutat, M.H.1
Vousden, K.H.2
-
32
-
-
0028928283
-
Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoiesis and a high incidence of P53 mutations
-
Lai JL, Preudhomme C, Zandecki M, Flactif M, Vanrumbeke M, Lepelley P, Wattel E, Fenaux P: Myelodysplastic syndromes and acute myeloid leukemia with 17p deletion. An entity characterized by specific dysgranulopoiesis and a high incidence of P53 mutations. Leukemia 1995;9:370-381.
-
(1995)
Leukemia
, vol.9
, pp. 370-381
-
-
Lai, J.L.1
Preudhomme, C.2
Zandecki, M.3
Flactif, M.4
Vanrumbeke, M.5
Lepelley, P.6
Wattel, E.7
Fenaux, P.8
-
33
-
-
9044247851
-
Distribution of TP53 mutations among acute leukemias with MLL rearrangements
-
Lanza C, Gaidano G, Cimino G, Pastore C, Nomdedeu J, Volpe G, Vivenza C, Parvis G, Mazza U, Basso G, Madon E, Lo Coco F, Saglio G: Distribution of TP53 mutations among acute leukemias with MLL rearrangements. Genes Chromosomes Cancer 1996;15:48-53.
-
(1996)
Genes Chromosomes Cancer
, vol.15
, pp. 48-53
-
-
Lanza, C.1
Gaidano, G.2
Cimino, G.3
Pastore, C.4
Nomdedeu, J.5
Volpe, G.6
Vivenza, C.7
Parvis, G.8
Mazza, U.9
Basso, G.10
Madon, E.11
Lo Coco, F.12
Saglio, G.13
-
34
-
-
0034725698
-
Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression
-
Laronga C, Yang HY, Neal C, Lee MH: Association of the cyclin-dependent kinases and 14-3-3 sigma negatively regulates cell cycle progression. J Biol Chem 2000;275:23106-23112.
-
(2000)
J Biol Chem
, vol.275
, pp. 23106-23112
-
-
Laronga, C.1
Yang, H.Y.2
Neal, C.3
Lee, M.H.4
-
35
-
-
0037459377
-
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation
-
Leng RP, Lin Y, Ma W, Wu H, Lemmers B, Chung S, Parant JM, Lozano G, Hakem R, Benchimol S: Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell 2003; 112:779-791.
-
(2003)
Cell
, vol.112
, pp. 779-791
-
-
Leng, R.P.1
Lin, Y.2
Ma, W.3
Wu, H.4
Lemmers, B.5
Chung, S.6
Parant, J.M.7
Lozano, G.8
Hakem, R.9
Benchimol, S.10
-
37
-
-
0030973238
-
Binding and modulation of p53 by p300/CBP coactivators
-
Lill NL, Grossman SR, Ginsberg D, DeCaprio J, Livingston DM: Binding and modulation of p53 by p300/CBP coactivators. Nature 1997; 387:823-827.
-
(1997)
Nature
, vol.387
, pp. 823-827
-
-
Lill, N.L.1
Grossman, S.R.2
Ginsberg, D.3
DeCaprio, J.4
Livingston, D.M.5
-
38
-
-
18444392071
-
The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia
-
Linggi B, Muller-Tidow C, van de Locht L, Hu M, Nip J, Serve H, Berdel WE, van der Reijden B, Quelle DE, Rowley JD, Cleveland J, Jansen JH, Pandolfi PP, Hiebert SW: The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia. Nat Med 2002;8:743-750.
-
(2002)
Nat Med
, vol.8
, pp. 743-750
-
-
Linggi, B.1
Muller-Tidow, C.2
Van De Locht, L.3
Hu, M.4
Nip, J.5
Serve, H.6
Berdel, W.E.7
Van Der Reijden, B.8
Quelle, D.E.9
Rowley, J.D.10
Cleveland, J.11
Jansen, J.H.12
Pandolfi, P.P.13
Hiebert, S.W.14
-
39
-
-
0033562638
-
Transcriptional inhibition of p53 by the MLL/MEN chimeric protein found in myeloid leukemia
-
Maki K, Mitani K, Yamagata T, Kurokawa M, Kanda Y, Yazaki Y, Hirai H: Transcriptional inhibition of p53 by the MLL/MEN chimeric protein found in myeloid leukemia. Blood 1999;93:3216-3224.
-
(1999)
Blood
, vol.93
, pp. 3216-3224
-
-
Maki, K.1
Mitani, K.2
Yamagata, T.3
Kurokawa, M.4
Kanda, Y.5
Yazaki, Y.6
Hirai, H.7
-
40
-
-
0037349289
-
p53 has a direct apoptogenic role at the mitochondria
-
Mihara M, Erster S, Zaika A, Petrenko O, Chittenden T, Pancoska P, Moll UM: p53 has a direct apoptogenic role at the mitochondria. Mol Cell 2003;11:577-590.
-
(2003)
Mol Cell
, vol.11
, pp. 577-590
-
-
Mihara, M.1
Erster, S.2
Zaika, A.3
Petrenko, O.4
Chittenden, T.5
Pancoska, P.6
Moll, U.M.7
-
41
-
-
0022623436
-
Human p53 gene localized to short arm of chromosome 17
-
Miller C, Mohandas T, Wolf D, Prokocimer M, Rotter V, Koeffler HP: Human p53 gene localized to short arm of chromosome 17. Nature 1986;319:783-784.
-
(1986)
Nature
, vol.319
, pp. 783-784
-
-
Miller, C.1
Mohandas, T.2
Wolf, D.3
Prokocimer, M.4
Rotter, V.5
Koeffler, H.P.6
-
42
-
-
0028939520
-
Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocation
-
Mitani K, Kanda Y, Ogawa S, Tanaka T, Inazawa J, Yazaki Y, Hirai H: Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11;19)(q23;p13.1) translocation. Blood 1995;85:2017-2024.
-
(1995)
Blood
, vol.85
, pp. 2017-2024
-
-
Mitani, K.1
Kanda, Y.2
Ogawa, S.3
Tanaka, T.4
Inazawa, J.5
Yazaki, Y.6
Hirai, H.7
-
43
-
-
0032211176
-
Chromosome band 1p36 contains a putative tumor suppressor gene important in the evolution of chronic myelogenous leukemia
-
Mori N, Morosetti R, Spira S, Lee S, Ben-Yehuda D, Schiller G, Landolf R, Mizoguchi H, Koeffler HP: Chromosome band 1p36 contains a putative tumor suppressor gene important in the evolution of chronic myelogenous leukemia. Blood 1998;92:3405-3409.
-
(1998)
Blood
, vol.92
, pp. 3405-3409
-
-
Mori, N.1
Morosetti, R.2
Spira, S.3
Lee, S.4
Ben-Yehuda, D.5
Schiller, G.6
Landolf, R.7
Mizoguchi, H.8
Koeffler, H.P.9
-
44
-
-
0029018161
-
Hemizygous expression of the wild-type p53 allele may confer a selective growth advantage before complete inactivation of the p53 gene in the progression of chronic myelogenous leukaemia
-
Nakai H, Misawa S, Horiike S, Maekawa T, Kashima K, Ishizaki K: Hemizygous expression of the wild-type p53 allele may confer a selective growth advantage before complete inactivation of the p53 gene in the progression of chronic myelogenous leukaemia. Br J Haematol 1995; 90:147-155.
-
(1995)
Br J Haematol
, vol.90
, pp. 147-155
-
-
Nakai, H.1
Misawa, S.2
Horiike, S.3
Maekawa, T.4
Kashima, K.5
Ishizaki, K.6
-
45
-
-
0037528708
-
Missense mutation and defective function of ATM in a childhood acute leukemia patient with MLL gene rearrangement
-
Oguchi K, Takagi M, Tsuchida R, Taya Y, Ito E, Isoyama K, Ishii E, Zannini L, Delia D, Mizutani S: Missense mutation and defective function of ATM in a childhood acute leukemia patient with MLL gene rearrangement. Blood 2003;101:3622-3627.
-
(2003)
Blood
, vol.101
, pp. 3622-3627
-
-
Oguchi, K.1
Takagi, M.2
Tsuchida, R.3
Taya, Y.4
Ito, E.5
Isoyama, K.6
Ishii, E.7
Zannini, L.8
Delia, D.9
Mizutani, S.10
-
46
-
-
0034644274
-
PML regulates p53 acetylation and premature senescence induced by oncogenic Ras
-
Pearson M, Carbone R, Sebastiani C, Cioce M, Fagioli M, Saito S, Higashimoto Y, Appella E, Minucci S, Pandolfi PP, Pelicci PG: PML regulates p53 acetylation and premature senescence induced by oncogenic Ras. Nature 2000;406: 207-210.
-
(2000)
Nature
, vol.406
, pp. 207-210
-
-
Pearson, M.1
Carbone, R.2
Sebastiani, C.3
Cioce, M.4
Fagioli, M.5
Saito, S.6
Higashimoto, Y.7
Appella, E.8
Minucci, S.9
Pandolfi, P.P.10
Pelicci, P.G.11
-
47
-
-
0025766195
-
BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner
-
Pendergast AM, Muller AJ, Havlik MH, Maru Y, Witte ON: BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner. Cell 1991;66: 161-171.
-
(1991)
Cell
, vol.66
, pp. 161-171
-
-
Pendergast, A.M.1
Muller, A.J.2
Havlik, M.H.3
Maru, Y.4
Witte, O.N.5
-
48
-
-
0034676332
-
BCR-ABL protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation
-
Pierce A, Spooncer E, Wooley S, Dive C, Francis JM, Miyan J, Owen-Lynch PJ, Dexter TM, Whetton AD: BCR-ABL protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation. Oncogene 2000;19:5487-5497.
-
(2000)
Oncogene
, vol.19
, pp. 5487-5497
-
-
Pierce, A.1
Spooncer, E.2
Wooley, S.3
Dive, C.4
Francis, J.M.5
Miyan, J.6
Owen-Lynch, P.J.7
Dexter, T.M.8
Whetton, A.D.9
-
49
-
-
13344284642
-
Incidence and characterization of MLL gene (11q23) rearrangements in acute myeloid leukemia M1 and M5
-
Poirel H, Rack K, Delabesse E, Radford-Weiss I, Troussard X, Debert C, Leboeuf D, Bastard C, Picard F, Veil-Buzyn A, Flandrin G, Bernard O, Macintyre E: Incidence and characterization of MLL gene (11q23) rearrangements in acute myeloid leukemia M1 and M5. Blood 1996;87:2496-2505.
-
(1996)
Blood
, vol.87
, pp. 2496-2505
-
-
Poirel, H.1
Rack, K.2
Delabesse, E.3
Radford-Weiss, I.4
Troussard, X.5
Debert, C.6
Leboeuf, D.7
Bastard, C.8
Picard, F.9
Veil-Buzyn, A.10
Flandrin, G.11
Bernard, O.12
Macintyre, E.13
-
50
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Pomerantz J, Schreiber-Agus N, Liegeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, Cordon-Cardo C, DePinho RA: The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 1998;92:713-723.
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
DePinho, R.A.12
-
51
-
-
0021004708
-
Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53
-
Reich NC, Oren M, Levine AJ: Two distinct mechanisms regulate the levels of a cellular tumor antigen, p53. Mol Cell Biol 1983;3:2143-2150.
-
(1983)
Mol Cell Biol
, vol.3
, pp. 2143-2150
-
-
Reich, N.C.1
Oren, M.2
Levine, A.J.3
-
52
-
-
0020008941
-
Chromosome abnormalities in malignant hematologic diseases
-
Rowley JD, Testa JR: Chromosome abnormalities in malignant hematologic diseases. Adv Cancer Res 1982;36:103-148.
-
(1982)
Adv Cancer Res
, vol.36
, pp. 103-148
-
-
Rowley, J.D.1
Testa, J.R.2
-
53
-
-
0031945625
-
Secondary acute leukemia and myelodys-plastic syndrome with 11q23 abnormalities. EU Concerted Action 11q23 Workshop
-
Secker-Walker LM, Moorman AV, Bain BJ, Mehta AB: Secondary acute leukemia and myelodys-plastic syndrome with 11q23 abnormalities. EU Concerted Action 11q23 Workshop. Leukemia 1998;12:840-844.
-
(1998)
Leukemia
, vol.12
, pp. 840-844
-
-
Secker-Walker, L.M.1
Moorman, A.V.2
Bain, B.J.3
Mehta, A.B.4
-
54
-
-
0035835824
-
PTEN: Life as a tumor suppressor
-
Simpson L, Parsons R: PTEN: Life as a tumor suppressor. Exp Cell Res 2001;264:29-41.
-
(2001)
Exp Cell Res
, vol.264
, pp. 29-41
-
-
Simpson, L.1
Parsons, R.2
-
55
-
-
0034898859
-
c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination
-
Sionov RV, Coen S, Goldberg Z, Berger M, Bercovich B, Ben-Neriah Y, Ciechanover A, Haupt Y: c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination. Mol Cell Biol 2001; 21:5869-5878.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 5869-5878
-
-
Sionov, R.V.1
Coen, S.2
Goldberg, Z.3
Berger, M.4
Bercovich, B.5
Ben-Neriah, Y.6
Ciechanover, A.7
Haupt, Y.8
-
56
-
-
0029850508
-
Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase
-
Skorski T, Nieborowska-Skorska M, Wlodarski P, Perrotti D, Martinez R, Wasik MA, Calabretta B: Blastic transformation of p53-deficient bone marrow cells by p210bcr/abl tyrosine kinase. Proc Natl Acad Sci USA 1996;93:13137-13142.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 13137-13142
-
-
Skorski, T.1
Nieborowska-Skorska, M.2
Wlodarski, P.3
Perrotti, D.4
Martinez, R.5
Wasik, M.A.6
Calabretta, B.7
-
57
-
-
0037043653
-
Campath-1H-induced complete remission of chronic lymphocytic leukemia despite p53 gene mutation and resistance to chemotherapy
-
Stilgenbauer S, Dohner H: Campath-1H-induced complete remission of chronic lymphocytic leukemia despite p53 gene mutation and resistance to chemotherapy. N Engl J Med 2002; 347:452-453.
-
(2002)
N Engl J Med
, vol.347
, pp. 452-453
-
-
Stilgenbauer, S.1
Dohner, H.2
-
58
-
-
0027279628
-
Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations
-
Thirman MJ, Gill HJ, Burnett RC, Mbangkollo D, McCabe NR, Kobayashi H, Zieminvan der Poel S, Kaneko Y, Morgan R, Sandberg AA et al: Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N Engl J Med 1993;329:909-914.
-
(1993)
N Engl J Med
, vol.329
, pp. 909-914
-
-
Thirman, M.J.1
Gill, H.J.2
Burnett, R.C.3
Mbangkollo, D.4
McCabe, N.R.5
Kobayashi, H.6
Ziemin-Van Der Poel, S.7
Kaneko, Y.8
Morgan, R.9
Sandberg, A.A.10
-
59
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts RS, Brumbaugh KM, Williams JM, Sarkaria JN, Cliby WA, Shieh SY, Taya Y, Prives C, Abraham RT: A role for ATR in the DNA damage-induced phosphorylation of p53. Genes Dev 1999;13:152-157.
-
(1999)
Genes Dev
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, J.M.3
Sarkaria, J.N.4
Cliby, W.A.5
Shieh, S.Y.6
Taya, Y.7
Prives, C.8
Abraham, R.T.9
-
60
-
-
0036674617
-
Live or let die: The cell's response to p53
-
Vousden KH, Lu X: Live or let die: The cell's response to p53. Nat Rev Cancer 2002;2:594-604.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 594-604
-
-
Vousden, K.H.1
Lu, X.2
-
61
-
-
0035195557
-
The evolution of diverse biological responses to DNA damage: Insights from yeast and p53
-
Wahl GM, Carr AM: The evolution of diverse biological responses to DNA damage: Insights from yeast and p53. Nat Cell Biol 2001;3: E277-E286.
-
(2001)
Nat Cell Biol
, vol.3
-
-
Wahl, G.M.1
Carr, A.M.2
-
62
-
-
0028125887
-
Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1
-
Ward Y, Gupta S, Jensen P, Wartmann M, Davis RJ, Kelly K: Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1. Nature 1994;367:651-654.
-
(1994)
Nature
, vol.367
, pp. 651-654
-
-
Ward, Y.1
Gupta, S.2
Jensen, P.3
Wartmann, M.4
Davis, R.J.5
Kelly, K.6
-
63
-
-
0028081261
-
The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin
-
Watanabe T, Hotta T, Ichikawa A, Kinoshita T, Nagai H, Uchida T, Murate T, Saito H: The MDM2 oncogene overexpression in chronic lymphocytic leukemia and low-grade lymphoma of B-cell origin. Blood 1994;84:3158-3165.
-
(1994)
Blood
, vol.84
, pp. 3158-3165
-
-
Watanabe, T.1
Hotta, T.2
Ichikawa, A.3
Kinoshita, T.4
Nagai, H.5
Uchida, T.6
Murate, T.7
Saito, H.8
-
64
-
-
0037417281
-
PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression
-
Yin Y, Liu YX, Jin YJ, Hall EJ, Barrett JC: PAC1 phosphatase is a transcription target of p53 in signalling apoptosis and growth suppression. Nature 2003;422:527-531.
-
(2003)
Nature
, vol.422
, pp. 527-531
-
-
Yin, Y.1
Liu, Y.X.2
Jin, Y.J.3
Hall, E.J.4
Barrett, J.C.5
-
65
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
Zhang Y, Xiong Y, Yarbrough WG: ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 1998; 92:725-734.
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
|