Bcr-Abl protein tyrosine kinase activity induces a loss of p53 protein that mediates a delay in myeloid differentiation

Oncogene

Volumn 19, Issue 48, 2000, Pages 5487-5497

  Pierce, Andrew ^a   Spooncer, Elaine ^a,b   Wooley, Sarah ^a   Dive, Caroline ^a   Francis, Julia M ^a   Miyan, Jaleel ^a   Owen Lynch, P Jane ^a   Dexter, T Michael ^b   Whetton, Anthony D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b CHRISTIE HOSPITAL   (United Kingdom)

Author keywords

Bcr Abl; CML; Differentiation; Haemopoietic; P53

Indexed keywords

BCR ABL PROTEIN; CELL MARKER; CELL PROTEIN; GROWTH FACTOR; INTERLEUKIN 3; PROTEIN P53; PROTEIN TYROSINE KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL DIFFERENTIATION; CELL GROWTH; CELL LEVEL; CELL LINE; CELL STRUCTURE; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; TEMPERATURE SENSITIVITY;

ANIMALS; CELL DIFFERENTIATION; FUSION PROTEINS, BCR-ABL; GENE SILENCING; GENES, P53; HUMANS; INTERLEUKIN-3; LEUKEMIA, MYELOID, CHRONIC; MICE; MYELOID CELLS; PROTEIN-TYROSINE KINASES; TEMPERATURE; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0034676332     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1203940     Document Type: Article

References (59)