Incidence and characterization of MLL gene (11q23) rearrangements in acute myeloid leukemia M1 and M5

Blood

Volumn 87, Issue 6, 1996, Pages 2496-2505

  Poirel, Hélène ^b   Rack, Katrina ^b   Delabesse, Eric ^b   Radford Weiss, Isabelle ^b   Troussard, Xavier ^b   Debert, Caroline ^b   Lebœuf, Daniel ^b   Bastard, Christian ^b   Picard, Françoise ^b   Veil Buzyn, Agnès ^b   Flandrin, Georges ^b   Bernard, Olivier ^b   Macintyre, Elizabeth ^a  

^a HÔPITAL NECKER ENFANTS MALADES   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CHROMOSOME 11Q; CHROMOSOME 6; CHROMOSOME ABERRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE FUSION; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; INCIDENCE; INFANT; MALE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 13344284642     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.6.2496.bloodjournal8762496     Document Type: Article

References (45)

1. Bloomfield C, Lawrence D, Arthur D, Berg D, Schiffer C, Mayer R: Curative impact of intensification with high-dose cytarabine (HIDAC) in acute myeloid leukemia (AML) varies by cytogenetic group. Blood 84:431, 1994
2. Mayer R, Davis R, Schiffer C, Berg D, Powell B, Schulman P, Omura G, Moore J, Mcintyre O, Frei E: Intensive postremission chemotherapy in adults with acute myeloid leukemia. N Engl J Med 331:896, 1994
3. Berger R, Flandrin G, Berheim A, Le Coniat M, Vecchione D, Pacot A, Derré J, Daniel M-T, Valensi F, Sigaux F, Ochoa-Noguera M-E: Cytogenetic studies on 519 de novo acute non lymphoblastic leukemias. Cancer Genet Cytogenet 29:9, 1987
4. Sandberg AA: The Chromosomes in Human Cancer and Leukemia, 2nd ed. New York, NY, Elsevier, 1990
5. Gu Y, Nakamura T, Alder H, Prasad R, Canaani O, Cimino G, Croce CM, Canaani E: The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to drosophilatrithorax, to the AF-4 gene. Cell 71:701, 1992
6. Tkachuk DC, Kohler S, Cleary ML: Involvement of a homolog of Drosophila-Trithorax by 11q23 chromosomal translocations in acute leukemias. Cell 71:691, 1992
7. Thirman MJ, Gill HJ, Burnett RC, Mbangkollo D, Mccabe NR, Kobayashi H, Zieminvanderpoel S, Kaneko Y, Morgan R, Sandberg AA, Chaganti RSK, Larson RA, Lebeau MM, Diaz MO. Rowley JD: Rearrangement of the MLL gene in acute lymphoblastic and acute mycloid leukemias with 11q23 chromosomal translocations. N Engl J Med 329:909, 1993
8. Bernard OA, Berger R: Molecular basis of 11q23 rearrangements in hematopoietic malignant proliferations. Genes Chromosom Cancer 13:75, 1995
9. Cherif D, Bernard O, Paulin S, James MR, Le Paslier D, Berger R: Hunting 11q23 deletions with FISH. Leukemia 8:578, 1994
10. Kobayashi H, Espinosa RI. Thirman M, Fernald A, Shannon K, Diaz M, Le Beau M, Rowley J: Do terminal deletions of 11q23 exist? Identification of undetected translocations with fluorescence in situ hybridization. Genes Chromosom Cancer 7:204, 1993
11. Iida S, Seto M, Yamamoto K, Komatsu H, Tojo A, Asano S, Kamada N, Ariyoshi Y, Takahashi T, Ueda R: MLLT3 gene on 9p22 involved in t(9;11) leukemia encodes a serine proline rich protein homologous to MLLT1 on 19p13. Oncogene 8:3085, 1993
12. Prasad R, Gu Y, Alder H, Nakamura T, Canaani O, Saito H, Huebner K, Gale RP, Nowell PC, Kuriyama K, Miyazaki Y, Croce CM, Canaani E: Cloning of the ALL-1 fusion partner, the AF-6 gene, involved in acute myeloid leukemias with the t(6; 11) chromosome translocation. Cancer Res 53:5624, 1993
13. Thirman MJ, Levitan DA, Kobayashi H, Celeste Simon M, Rowley JD: Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia. Proc Natl Acad Sci USA 91:12110, 1994
14. Mitani K, Kanda Y, Ogawa S, Tanaka T, Inazawa J, Yazaki Y, Hirai H: Cloning of several species of MLL/MEN chimeric cDNAs in myeloid leukemia with t(11,19)(q23;p13.1) transiocation. Blood 85:2017, 1995
15. Rubnitz JE, Morrissey J, Savage PA, Cleary ML: ENL, the gene fused with HRX in t(11;19) leukemias, encodes a nuclear protein with transcriptional actuation potential in lymphoid and myeloid cells. Blood 84:1747, 1994
16. Cimino G, Rapanotti MC, Rivolta A, Lo Coco F, D'Arcanselo E, Rondelli R, Basso G, Barisone E, Rosanda C, Santostasi T, Canaani E, Masera G, Mandelli F. Biondi A: Prognosis relevance of ALL-1 gene rearrangement in infant acute leukemias. Leukemia 9:391, 1995
17. Parry P, Djabali M, Bower M, Khristich J, Waterman M, Gibbons B, Young BD, Evans G: Structure and expression of the human Trithorax-like gene-1 involved in acute leukemias. Proc Natl Acad Sci USA 90:4738, 1993
18. Le Coniat M, Romana SP, Bernard O, Flexor M-A, Hillion J, Cherif D, Berger R: A novel translocation t(9;11)(q33;q23) involving HRX in an acute monocytic leukemia. C R Acad Sci Life Sci 316:692, 1993
19. Cimino G, Lococo F, Biondi A, Elia L, Luciano A, Croce CM, Masera G, Mandelli F, Canaani E: ALL-1 gene at chromosome 11q23 is consistently altered in acute leukemia of early infancy. Blood 82:544, 1993
20. Bower M, Parry P, Carter M, Lillington DM, Amess J, Lister TA, Evans GA, Young BD: Prevalence and clinical correlations of MLL gene rearrangements in AML-M4/5. Blood 84:3776, 1995
21. Cimino G, Rapanotti MC, Elia L, Biondi A, Fizzotti M, Testi AM, Tosti S, Croce CM, Canaani E, Mandelli F, Lococo F: ALL-1 gene rearrangements in acute myeloid leukemia: Association with M4-M5 French-American-British classification subtypes and young age. Cancer Res 55:1625, 1995
22. Schichman SA, Caligiuri MA, Strout MP, Carter SL, Gu Y, Canaani E, Bloomfield CD, Croce CM: ALL-1 tandem duplication in acute myeloid leukemia with a normal karyotype involves homologous recombination between Alu elements. Cancer Res 54:4277, 1994
23. Bernard O, Romana S, Schichman S, Mauchauffe M, Jonveaux P, Berger R: Partial duplication of HRX in acute leukemia with trisomy 11. Leukemia 9:1487, 1995
24. Arthur DC, Berger R, Colomb HM, Swansbury GJ, Reeves BR, Alimena G, Van Den Berghe H, Bloomfield CD, de la Chapelle A, Dewald GW, Garson OM, Hagemeijer A, Kaneko Y, Miteiman F, Pierre RV, Ruutu T, Sakurai M, Lawler SD, Rowley JD: The clinical significance of karyotype in acute myelogenous leukemia. Cancer Genet Cytogenet 40:203, 1989
25. Kalwinsky D, Raimondi S, Schell M, Mirro J, Santana V, Behm F, Dahl G, Williams D: Prognostic importance of cytogenetic subgroups in de novo pediatric non lymphocytic leukemia. J Clin Oncol 8:75, 1990
26. Chen CS, Sorensen PHB, Domer PH, Reaman GH, Korsmeyer SJ, Heerema NA, Hammond GD, Kersey JH: Molecular rearrangements on chromosome-11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcome. Blood 81:2386, 1993
27. Heerema NA, Arthur DC, Sather H, Albo V, Feusner J, Lange BJ, Steinherz PG, Zeltzer P, Hammond D, Reaman GH: Cytogenetic features of infant less than 12 months of age at diagnosis of acute lymphoblastic leukemia: Impact of the 11q23 breakpoint on outcome: A repon of the Children Cancer Group. Blood 83:2274, 1994
28. Raimondi SC, Frestedt JL, Pui C-H, Downing JR, Head DR, Kersey JH, Behm FG: Acute lymphoblastic leukemias with deletion of 11q23 or a novel inversion (11)(p13q23) lack MLL rearrangements and have favorable clinical features. Blood 86:1881, 1995
29. Poirel H, Radford-Weiss I, Rack K, Troussard X, Veil A, Valensi F, Picard F, Guesnu M, Lebœuf D, Meile J, Dreyfus F, Flandrin G, Macintyre E: Detection of the chromosome 16 CBFβ-MYH11 fusion transcript in myelomonocytic leukemias. Blood 85:1313, 1995
30. Bennett JM, Catovsky D, Daniel M-T, Flandrin G, Galton DAG, Gralnick HR, Sultan C: Proposed revised criteria for the classification of acute myeloid leukemia: A report of the French-American-British Cooperative Group. Ann Intern Med 103:626, 1985
31. Mitelman F: Guidelines for Cancer Cytogenetics, Supplement to an International System for Human Cytogenetic Nomenclature (ISCN). Basel, Switzerland, Karger Basel, 1991
32. Finke J, Fritzen R, Ternes P, Lange W, Dolken G: An improved strategy and a useful housekeeping gene for RNA analysis from formalin-fixed, paraffin-embedded tissues by PCR. Biotechniques 14:448, 1993
33. Kearney L, Bower M, Gibbons B, Das S, Chaplin T, Nacheva E, Chessells JM, Reeves B, Riley JH, Lister TA, Young BD: Chromosome 11q23 translocations in both infant and adult acute leukemias are detected by in situ hybridization with a yeast artificial chromosome. Blood 80:1659, 1992
34. Rowley JD: Human oncogene locations and chromosome aberrations. Nature 301:290, 1983
35. Cuneo A, Michaux JL, Ferrant A, Van Hove L, Bosly A, Stul M, Dal Cin P, Vandenberghe E, Cassiman JJ, Negrini M, Piva N, Gianluigi C, Van Den Berghe H: Correlation of cytogenetic patterns and clinicobiological features in adult acute myeloid leukemia expressing lymphoid markers. Blood 79:720, 1992
36. Schichman SA, Caligiuri MA, Gu Y, Strout MP, Canaani E, Bloomfield CD, Croce CM: ALL-1 partial duplication in acute leukemia. Proc Natl Acad Sci USA 91:6236, 1994
37. Nakamura T, Alder H, Gu Y, Prasad R, Canaani O, Kamada N, Gale RP, Lange B, Crist WM, Nowell PC, Croce CM, Canaani E: Genes on chromosome-4, chromosome-9, and chromosome-19 involved in 11q23 abnormalities in acute leukemia share sequence homology and/or common motifs. Proc Natl Acad Sci USA 90:4631, 1993
38. Yamamoto K, Seto M, Iida S, Komatsu H, Kamada N, Kojima S, Kodera Y, Nakazawa S, Saito H, Takahashi T, Ueda R: A reverse transcriptase-polymerase chain reaction detects heterogeneous chimeric mRNAs in leukemias with 11q23 abnormalities. Blood 83:2912, 1994
39. Schichman SA, Canaani E, Croce CM: Self fusion of the ALL1 gene. JAMA 273:571, 1995
40. Hilden JM, Chen CS, Moore R, Frestedt J, Kersey JH: Heterogeneity in MLL/AF-4 fusion messenger RNA detected by the polymerase chain reaction in t(4;11) acute leukemia. Cancer Res 53:3853, 1993
41. Morris CM, Heisterkamp N, Kennedy MA, Fitzgerald PH, Groffen J: Ph-negative chronic myeloid leukemia: Molecular analysis of ABL insertion into M-BCR on chromosome 22. Blood 76:1812, 1990
42. Lafage-Pochitaloff M, Alcalay M, Brunei V, Longo L, Sainty D, Simonetti J, Birg F, Pelicci P: Acute promyelocytic leukemia cases with nonreciprocal PML/RARa or RARa/PML fusion genes. Blood 85:1169, 1995
43. French Registry of Acute Leukemia and Myelodysplastic Syndromes: Age distribution and hemogram analysis of the 4496 cases recorded during 1982-1983 and classified according to the FAB criteria. Cancer 60:1385, 1987
44. Corral J, Forster A, Thompson S, Lampert F, Kaneko Y, Slater R, Kroes WG, Vanderschoot CE, Ludwig WD, Karpas A, Pocock C, Cotter F, Rabbins TH: Acute leukemias of different lineages have similar MLL gene fusions encoding related chimeric proteins resulting from chromosomal translocation. Proc Natl Acad Sci USA 90:8538, 1993
45. Repp R, Borkhardt A, Haupt E, Kreuder J, Brettreich S, Hammermann J, Nishida K, Harbott J, Lampert F: Detection of four different 11q23 chromosomal abnormalities by multiplex-PCR and fluorescence-based automatic DNA-fragment analysis. Leukemia 9:210, 1995