Distinct genetic involvement of the TP53 gene in therapy-related leukemia and myelodysplasia with chromosomal losses of Nos 5 and/or 7 and its possible relationship to replication error phenotype

Leukemia

Volumn 13, Issue 8, 1999, Pages 1235-1242

  Horiike, S ^a   Misawa, S ^b   Kaneko, H ^b   Sasai, Y ^b   Kobayashi, M ^b   Fujii, H ^b   Tanaka, S ^b   Yagita, M ^b   Abe, T ^b   Kashima, K ^b   Taniwaki, M ^b  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b NONE

Author keywords

Chromosomes; DNA mismatch repair genes; Microsatellite instability; Myelodysplastic syndrome; p53; Therapy related leukemia

Indexed keywords

ALKYLATING AGENT; DNA; DNA TOPOISOMERASE INHIBITOR; PROTEIN P53;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BONE MARROW CELL; CHROMOSOME 5; CHROMOSOME 7; CLINICAL ARTICLE; CONTROLLED STUDY; DNA REPAIR; DNA REPLICATION; DRUG INDUCED CANCER; FIBROBLAST; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; MICROSATELLITE INSTABILITY; MISSENSE MUTATION; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; VOLUNTEER;

EID: 0032868343     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2401466     Document Type: Article

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