메뉴 건너뛰기




Volumn 23, Issue 24, 2003, Pages 8946-8952

Human β-Globin Locus Control Region HS5 Contains CTCF- and Developmental Stage-Dependent Enhancer-Blocking Activity in Erythroid Cells

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLOBIN; DEOXYRIBONUCLEASE I; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CTCF; UNCLASSIFIED DRUG;

EID: 0344629446     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.24.8946-8952.2003     Document Type: Article
Times cited : (49)

References (38)
  • 1
    • 0030826364 scopus 로고    scopus 로고
    • Intergenic transcription and transinduction of the human beta-globin locus
    • Ashe, H. L., J. Monks, M. Wijgerde, P. Fraser, and N. J. Proudfoot. 1997. Intergenic transcription and transinduction of the human beta-globin locus. Genes Dev. 11:2494-2509.
    • (1997) Genes Dev. , vol.11 , pp. 2494-2509
    • Ashe, H.L.1    Monks, J.2    Wijgerde, M.3    Fraser, P.4    Proudfoot, N.J.5
  • 2
    • 0033529654 scopus 로고    scopus 로고
    • The protein CTCF is required for the enhancer-blocking activity of vertebrate insulators
    • Bell, A. C., A. G. West, and G. Felsenfeld. 1999. The protein CTCF is required for the enhancer-blocking activity of vertebrate insulators. Cell 98:387-396.
    • (1999) Cell , vol.98 , pp. 387-396
    • Bell, A.C.1    West, A.G.2    Felsenfeld, G.3
  • 3
    • 0032402123 scopus 로고    scopus 로고
    • Description and targeted deletion of 5′ hypersensitive site 5 and 6 of the mouse beta-globin locus control region
    • Bender, M. A., A. Reik, J. Close, A. Telling, E. Epner, S. Fiering, R. Hardison, and M. Groudine. 1998. Description and targeted deletion of 5′ hypersensitive site 5 and 6 of the mouse beta-globin locus control region. Blood 92:4394-4403.
    • (1998) Blood , vol.92 , pp. 4394-4403
    • Bender, M.A.1    Reik, A.2    Close, J.3    Telling, A.4    Epner, E.5    Fiering, S.6    Hardison, R.7    Groudine, M.8
  • 6
    • 0029558513 scopus 로고
    • Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4
    • Bungert, J., U. Dave, K. C. Lim, K. H. Lieuw, J. A. Shavit, Q. Liu, and J. D. Engel. 1995. Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4. Genes Dev. 9:3083-3096.
    • (1995) Genes Dev. , vol.9 , pp. 3083-3096
    • Bungert, J.1    Dave, U.2    Lim, K.C.3    Lieuw, K.H.4    Shavit, J.A.5    Liu, Q.6    Engel, J.D.7
  • 7
    • 0032912801 scopus 로고    scopus 로고
    • Hypersensitive site 2 specifies a unique function within the human beta-globin locus control region to stimulate globin gene transcription
    • Bungert, J., K. Tanimoto, S. Patel, Q. Liu, M. Fear, and J. D. Engel. 1999. Hypersensitive site 2 specifies a unique function within the human beta-globin locus control region to stimulate globin gene transcription. Mol. Cell. Biol. 19:3062-3072.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3062-3072
    • Bungert, J.1    Tanimoto, K.2    Patel, S.3    Liu, Q.4    Fear, M.5    Engel, J.D.6
  • 8
    • 0024280908 scopus 로고
    • Developmental regulation of beta-globin gene switching
    • Choi, O.-R., and J. D. Engel. 1988. Developmental regulation of beta-globin gene switching. Cell 55:17-26.
    • (1988) Cell , vol.55 , pp. 17-26
    • Choi, O.-R.1    Engel, J.D.2
  • 10
    • 0027254748 scopus 로고
    • A 5′ element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila
    • Chung, J. H., M. Whiteley, and G. Felsenfeld. 1993. A 5′ element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila. Cell 74:505-514.
    • (1993) Cell , vol.74 , pp. 505-514
    • Chung, J.H.1    Whiteley, M.2    Felsenfeld, G.3
  • 12
    • 0034598936 scopus 로고    scopus 로고
    • Looping, linking, and chromatin activity: New insights into beta-globin locus regulation
    • Engel, J. D., and K. Tanimoto. 2000. Looping, linking, and chromatin activity: new insights into beta-globin locus regulation. Cell 100:499-502.
    • (2000) Cell , vol.100 , pp. 499-502
    • Engel, J.D.1    Tanimoto, K.2
  • 13
    • 0034687661 scopus 로고    scopus 로고
    • A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta-globin locus
    • Farrell, C. M., A. Grinberg, S. P. Huang, D. Chen, J. G. Pichel, H. Westphal, and G. Felsenfeld. 2000. A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta-globin locus. Proc. Natl. Acad. Sci. USA 97:14554-14559.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14554-14559
    • Farrell, C.M.1    Grinberg, A.2    Huang, S.P.3    Chen, D.4    Pichel, J.G.5    Westphal, H.6    Felsenfeld, G.7
  • 14
    • 0036094107 scopus 로고    scopus 로고
    • Conserved CTCF insulator elements flank the mouse and human beta-globin loci
    • Farrell, C. M., A. G. West, and G. Felsenfeld. 2002. Conserved CTCF insulator elements flank the mouse and human beta-globin loci. Mol. Cell. Biol. 22:3820-3831.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3820-3831
    • Farrell, C.M.1    West, A.G.2    Felsenfeld, G.3
  • 15
    • 0032847723 scopus 로고    scopus 로고
    • An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells
    • Feingold, E. A., L. A. Penny, A. W. Nienhuis, and B. G. Forget. 1999. An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells. Genomics 61:15-23.
    • (1999) Genomics , vol.61 , pp. 15-23
    • Feingold, E.A.1    Penny, L.A.2    Nienhuis, A.W.3    Forget, B.G.4
  • 16
    • 0028179012 scopus 로고
    • The chicken beta/epsilon-globin enhancer directs autonomously regulated, high-level expression of the chicken epsilon-globin gene in transgenic mice
    • Foley, K. P., S. Pruzina, J. D. Winick, J. D. Engel, F. Grosveld, and P. Fraser. 1994. The chicken beta/epsilon-globin enhancer directs autonomously regulated, high-level expression of the chicken epsilon-globin gene in transgenic mice. Proc. Natl. Acad. Sci. USA 91:7252-7256.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 7252-7256
    • Foley, K.P.1    Pruzina, S.2    Winick, J.D.3    Engel, J.D.4    Grosveld, F.5    Fraser, P.6
  • 17
    • 0025866045 scopus 로고
    • Physical mapping of yeast artificial chromosomes containing sequences from the human beta-globin gene region
    • Gaensler, K. M., M. Burmeister, B. H. Brownstein, P. Taillon-Miller, and R. M. Myers. 1991. Physical mapping of yeast artificial chromosomes containing sequences from the human beta-globin gene region. Genomics 10: 976-984.
    • (1991) Genomics , vol.10 , pp. 976-984
    • Gaensler, K.M.1    Burmeister, M.2    Brownstein, B.H.3    Taillon-Miller, P.4    Myers, R.M.5
  • 18
    • 0030921097 scopus 로고    scopus 로고
    • Transcription of the HS2 enhancer toward a cis-linked gene is independent of the orientation, position, and distance of the enhancer relative to the gene
    • Kong, S., D. Bohl, C. Li, and D. Tuan. 1997. Transcription of the HS2 enhancer toward a cis-linked gene is independent of the orientation, position, and distance of the enhancer relative to the gene. Mol. Cell. Biol. 17:3955-3965.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3955-3965
    • Kong, S.1    Bohl, D.2    Li, C.3    Tuan, D.4
  • 19
    • 0032938120 scopus 로고    scopus 로고
    • Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus
    • Lakshmanan, G., K. H. Lieuw, K. C. Lim, Y. Gu, F. Grosveld, J. D. Engel, and A. Karis. 1999. Localization of distant urogenital system-, central nervous system-, and endocardium-specific transcriptional regulatory elements in the GATA-3 locus. Mol. Cell. Biol. 19:1558-1568.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 1558-1568
    • Lakshmanan, G.1    Lieuw, K.H.2    Lim, K.C.3    Gu, Y.4    Grosveld, F.5    Engel, J.D.6    Karis, A.7
  • 20
    • 0035076274 scopus 로고    scopus 로고
    • Reconstitution of human beta-globin locus control region hypersensitive sites in the absence of chromatin assembly
    • Leach, K. M., K. Nightingale, K. Igarashi, P. P. Levings, J. D. Engel, P. B. Becker, and J. Bungert. 2001. Reconstitution of human beta-globin locus control region hypersensitive sites in the absence of chromatin assembly. Mol. Cell. Biol. 21:2629-2640.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 2629-2640
    • Leach, K.M.1    Nightingale, K.2    Igarashi, K.3    Levings, P.P.4    Engel, J.D.5    Becker, P.B.6    Bungert, J.7
  • 21
    • 0036227306 scopus 로고    scopus 로고
    • The human beta-globin locus control region
    • Levings, P. P., and J. Bungert. 2002. The human beta-globin locus control region. Eur. J. Biochem. 269:1589-1599.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 1589-1599
    • Levings, P.P.1    Bungert, J.2
  • 22
    • 0036606545 scopus 로고    scopus 로고
    • Evidence that DNase I hypersensitive site 5 of the human beta-globin locus control region functions as a chromosomal insulator in transgenic mice
    • Li, Q., M. Zhang, H. Han, A. Rohde, and G. Stamatoyannopoulos. 2002. Evidence that DNase I hypersensitive site 5 of the human beta-globin locus control region functions as a chromosomal insulator in transgenic mice. Nucleic Acids Res. 30:2484-2491.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 2484-2491
    • Li, Q.1    Zhang, M.2    Han, H.3    Rohde, A.4    Stamatoyannopoulos, G.5
  • 23
    • 0035451090 scopus 로고    scopus 로고
    • CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease
    • Ohlsson, R., R. Renkawitz, and V. Lobanenkov. 2001. CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease. Trends Genet. 17:520-527.
    • (2001) Trends Genet. , vol.17 , pp. 520-527
    • Ohlsson, R.1    Renkawitz, R.2    Lobanenkov, V.3
  • 24
    • 0034811678 scopus 로고    scopus 로고
    • Intergenic transcription in the human beta-globin gene cluster
    • Plant, K. E., S. J. Routledge, and N. J. Proudfoot. 2001. Intergenic transcription in the human beta-globin gene cluster. Mol. Cell. Biol. 21:6507-6514.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 6507-6514
    • Plant, K.E.1    Routledge, S.J.2    Proudfoot, N.J.3
  • 25
    • 0030709312 scopus 로고    scopus 로고
    • The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice
    • Porcu, S., M. Kitamura, E. Witkowska, Z. Zhang, A. Mutero, C. Lin, J. Chang, and K. M. Gaensler. 1997. The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice. Blood 90:4602-4609.
    • (1997) Blood , vol.90 , pp. 4602-4609
    • Porcu, S.1    Kitamura, M.2    Witkowska, E.3    Zhang, Z.4    Mutero, A.5    Lin, C.6    Chang, J.7    Gaensler, K.M.8
  • 26
    • 0033565868 scopus 로고    scopus 로고
    • An insulator element and condensed chromatin region separate the chicken beta-globin locus from an independently regulated erythroid-specific folate receptor gene
    • Prioleau, M. N., P. Nony, M. Simpson, and G. Felsenfeld. 1999. An insulator element and condensed chromatin region separate the chicken beta-globin locus from an independently regulated erythroid-specific folate receptor gene. EMBO J. 18:4035-4048.
    • (1999) EMBO J. , vol.18 , pp. 4035-4048
    • Prioleau, M.N.1    Nony, P.2    Simpson, M.3    Felsenfeld, G.4
  • 27
    • 0033839103 scopus 로고    scopus 로고
    • A (GATA)(7) motif located in the 5′ boundary area of the human beta-globin locus control region exhibits silencer activity in erythroid cells
    • Ramchandran, R., C. Bengra, B. Whitney, K. Lanclos, and D. Tuan. 2000. A (GATA)(7) motif located in the 5′ boundary area of the human beta-globin locus control region exhibits silencer activity in erythroid cells. Am. J. Hematol. 65:14-24.
    • (2000) Am. J. Hematol. , vol.65 , pp. 14-24
    • Ramchandran, R.1    Bengra, C.2    Whitney, B.3    Lanclos, K.4    Tuan, D.5
  • 29
    • 0036978961 scopus 로고    scopus 로고
    • Definition of transcriptional promoters in the human Beta globin locus control region
    • Routledge, S. J., and N. J. Proudfoot. 2002. Definition of transcriptional promoters in the human Beta globin locus control region. J. Mol. Biol. 323:601-611.
    • (2002) J. Mol. Biol. , vol.323 , pp. 601-611
    • Routledge, S.J.1    Proudfoot, N.J.2
  • 30
    • 0032840462 scopus 로고    scopus 로고
    • Enhancer-blocking by the Drosophila gypsy insulator depends upon insulator anatomy and enhancer strength
    • Scott, K. C., A. D. Taubman, and P. K. Geyer. 1999. Enhancer-blocking by the Drosophila gypsy insulator depends upon insulator anatomy and enhancer strength. Genetics 153:787-798.
    • (1999) Genetics , vol.153 , pp. 787-798
    • Scott, K.C.1    Taubman, A.D.2    Geyer, P.K.3
  • 31
  • 32
    • 0033602445 scopus 로고    scopus 로고
    • Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice
    • Tanimoto, K., Q. Liu, J. Bungert, and J. D. Engel. 1999. Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice. Nature 398:344-348.
    • (1999) Nature , vol.398 , pp. 344-348
    • Tanimoto, K.1    Liu, Q.2    Bungert, J.3    Engel, J.D.4
  • 33
    • 0033178262 scopus 로고    scopus 로고
    • The polyoma virus enhancer cannot substitute for DNase I core hypersensitive sites 2-4 in the human beta-globin LCR
    • Tanimoto, K., Q. Liu, J. Bungert, and J. D. Engel. 1999. The polyoma virus enhancer cannot substitute for DNase I core hypersensitive sites 2-4 in the human beta-globin LCR. Nucleic Acids Res. 27:3130-3137.
    • (1999) Nucleic Acids Res. , vol.27 , pp. 3130-3137
    • Tanimoto, K.1    Liu, Q.2    Bungert, J.3    Engel, J.D.4
  • 34
    • 0034312291 scopus 로고    scopus 로고
    • Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice
    • Tanimoto, K., Q. Liu, F. Grosveld, J. Bungert, and J. D. Engel. 2000. Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice. Genes Dev. 14:2778-2794.
    • (2000) Genes Dev. , vol.14 , pp. 2778-2794
    • Tanimoto, K.1    Liu, Q.2    Grosveld, F.3    Bungert, J.4    Engel, J.D.5
  • 35
    • 0026482145 scopus 로고
    • Transcription of the hypersensitive site HS2 enhancer in erythroid cells
    • Tuan, D., S. Kong, and K. Hu. 1992. Transcription of the hypersensitive site HS2 enhancer in erythroid cells. Proc. Natl. Acad. Sci. USA 89:11219-11223.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11219-11223
    • Tuan, D.1    Kong, S.2    Hu, K.3
  • 36
    • 0028180340 scopus 로고
    • A 5′ beta-globin matrix-attachment region and the polyoma enhancer together confer position-independent transcription
    • Yu, J., J. H. Bock, J. L. Slightom, and B. Villeponteau. 1994. A 5′ beta-globin matrix-attachment region and the polyoma enhancer together confer position-independent transcription. Gene 139:139-145.
    • (1994) Gene , vol.139 , pp. 139-145
    • Yu, J.1    Bock, J.H.2    Slightom, J.L.3    Villeponteau, B.4
  • 38
    • 0002241613 scopus 로고
    • The regulation of human β-globin gene expression: The analysis of hypersensitive site 5 (βHS5) in the LCR
    • G. Stamatoyannopoulos (ed.). Intercept Ltd., Andover, United Kingdom
    • Zafarana, G., S. Raguz, S. Pruzina, F. Grosveld, and D. Meijer. 1995. The regulation of human β-globin gene expression: the analysis of hypersensitive site 5 (βHS5) in the LCR, p. 39-44. In G. Stamatoyannopoulos (ed.), Molecular biology of hemoglobin switching. Intercept Ltd., Andover, United Kingdom.
    • (1995) Molecular Biology of Hemoglobin Switching , pp. 39-44
    • Zafarana, G.1    Raguz, S.2    Pruzina, S.3    Grosveld, F.4    Meijer, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.