Twin priming: A proposed mechanism for the creation of inversions in L1 retrotransposition

Genome Research

Volumn 11, Issue 12, 2001, Pages 2059-2065

  Ostertag, E M ^a   Kazazian H H , Jr ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEASE; DNA; DOUBLE STRANDED DNA; ENDONUCLEASE; POLYADENYLIC ACID; PRIMER RNA; SINGLE STRANDED DNA;

ARTICLE; CONTROLLED STUDY; DATA BASE; DNA STRAND BREAKAGE; GENE SEQUENCE; GENE TARGETING; GENETIC ANALYSIS; GENETIC PROCEDURES; GENOME; HUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; RETROPOSON; REVERSE TRANSCRIPTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

DNA, SINGLE-STRANDED; HUMANS; INVERSION, CHROMOSOME; MODELS, GENETIC; RETROELEMENTS; SEQUENCE HOMOLOGY, NUCLEIC ACID; TRANSCRIPTION, GENETIC;

EID: 0035208118     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.205701     Document Type: Article

References (26)

1. Basic local alignment search tool
2. GenBank
3. Selection against deleterious LINE-1-containing loci in the human lineage
4. Molecular structure of canine LINE-1 elements in canine transmissible venereal tumor
5. Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure
6. DNA double-strand break repair in cell-free extracts from Ku80-deficient cells: Implications for Ku serving as an alignment factor in non-homologous DNA end joining
7. Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition
8. Fidelity of retrotransposon replication
9. Transduction of 3′-flanking sequences is common in L1 retrotransposition
10. Rejoining of DNA double-strand breaks in vitro by single-strand annealing
11. A new retrotransposable human L1 element from the LRE2 locus on chromosome 1q produces a chimaeric insertion
12. LINES and related retroposons: Long interspersed sequences in the eucaryotic genome
13. Initial sequencing and analysis of the human genome
14. Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons
15. Determination of the site of first strand transfer during Moloney murine leukemia virus reverse transcription and identification of strand transfer-associated reverse transcriptase errors
16. Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition
17. The age and evolution of non-LTR retrotransposable elements
18. A new exon created by intronic insertion of a rearranged LINE-1 element as the cause of chronic granulomatous disease
19. Extension of mismatched 3′ termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase
20. Mechanisms of overlap formation in nonhomologous DNA end joining
21. High rate of mismatch extension during reverse transcription in a single round of retrovirus replication
22. The RAG1/RAG2 complex constitutes a 3′ flap endonuclease: Implications for junctional diversity in V(D)J and transpositional recombination
23. The abundant LINE-1 family of repeated DNA sequences in mammals: Genes and pseudogenes
24. A mechanism for deletion formation in DNA by human cell extracts: The involvement of short sequence repeats
25. Human L1 retrotransposition: Cis preference versus trans complementation
26. Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates