A comprehensive analysis of recently integrated human Ta L1 elements

American Journal of Human Genetics

Volumn 71, Issue 2, 2002, Pages 312-326

  Myers, Jeremy S ^a,b   Vincent, Bethaney J ^a,b   Udall, Hunt ^b   Watkins, W Scott ^c   Morrish, Tammy A ^d   Kilroy, Gail E ^a   Swergold, Gary D ^e   Henke, Jurgen ^f   Henke, Lotte ^f   Moran, John V ^d   Jorde, Lynn B ^c   Batzer, Mark A ^a,b  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e Columbia University ^*  (United States)

^f Institut Fur Blutgruppenforschung   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENE CONVERSION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC RECOMBINATION; GENETIC SCREENING; HUMAN; HUMAN CELL; LONG INTERSPERSED REPEAT; OPEN READING FRAME; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FAMILY; RETROPOSON; RNA TRANSLATION; SEQUENCE ANALYSIS;

INSERTION SEQUENCES; PAN PANISCUS; PAN TROGLODYTES; PANISCUS; PRIMATES; TROGLODYTES;

EID: 0036073862     PISSN: 00029297     EISSN: None     Source Type: Journal    
DOI: 10.1086/341718     Document Type: Article

References (70)

1. Basic local alignment search tool
2. Alu repeats: A source for the genesis of primate microsatellites
3. Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion
4. Alu repeats and human genomic diversity
5. Amplification dynamics of human-specific (HS) Alu family members
6. Dispersion and insertion polymorphism in two small subfamilies of recently amplified human Alu repeats
7. African origin of human-specific polymorphic Alu insertions
8. DNA methylation and the frequency of CpG in animal DNA
9. LINEs and Alus-The polyA connection
10. Retroshuffling the genomic deck
11. L1 (LINE-1) retrotransposon evolution and amplification in recent human history
12. Selection against deleterious LINE-1-containing loci in the human lineage
13. Construction of a genetic linkage map in man using restriction fragment length polymorphisms
14. Selection on Alu sequences?
15. L1 gene conversion or same-site transposition
16. Large-scale analysis of the Alu Ya5 and Yb8 subfamilies and their contribution to human genomic diversity
17. Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure
18. Target DNA chromatinization modulates nicking by L1 endonuclease
19. Master genes in mammalian repetitive DNA amplification
20. Isolation of an active human transposable element
21. The polydeoxyadenylate tract of Alu repetitive elements is polymorphic in the human genome
22. Anomalous migration of PCR products using nondenaturing polyacrylamide gel electrophoresis: The amelogenin sex-typing system
23. LINE-1: A mammalian transposable element
24. Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition
25. Duplication of the γ-globin gene mediated by L1 long interspersed repetitive elements in an early ancestor of simian primates
26. Gene conversion and different population histories may explain the contrast between polymorphism and linkage disequilibrium levels
27. Transduction of 3′-flanking sequences is common in L1 retrotransposition
28. Defining the beginning and end of KpnI family segments
29. A recent insertion of an Alu element on the Y chromosome is a useful marker for human population studies
30. An analysis of replacement and synonymous changes in the rodent L1 repeat family
31. The distribution of human genetic diversity: A comparison of mitochondrial, autosomal, and Y-chromosome data
32. Sequence patterns indicate an enzymatic involvement in integration of mammalian retroposons
33. CENSOR-A program for identification and elimination of repetitive elements from DNA sequences
34. Gene conversion as a secondary mechanism of short interspersed element (SINE) evolution
35. Mobile elements and disease
36. L1 retrotransposons shape the mammalian genome
37. The impact of L1 retrotransposons on the human genome
38. Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man
39. Recent amplification of rat ID sequences
40. Initial sequencing and analysis of the human genome
41. Reverse transcription of R2Bm RNA is primed by a nick at the chromosomal target site: A mechanism for non-LTR retrotransposition
42. Molecular evolution of intergenic DNA in higher primates: Pattern of DNA changes, molecular clock, and evolution of repetitive sequences
43. Phylogenetic relations of humans and African apes from DNA sequences in the psi eta-globin region
44. Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks
45. Exon shuffling by L1 retrotransposition
46. High frequency retrotransposition in cultured mammalian cells
47. DNA repair mediated by endonuclease-independent LINE-1 retrotransposition
48. Variable number of tandem repeat (VNTR) markers for human gene mapping
49. Twin priming: A proposed mechanism for the creation of inversions in L1 retrotransposition
50. Determination of L1 retrotransposition kinetics in cultured cells
51. Genomic characterization of recent human LINE-1 insertions: Evidence supporting random insertion
52. Alu insertion polymorphism: A new type of marker for human population studies
53. Mobile elements and the human genome
54. Promoter of the gene encoding the 16 kDa DNA-binding and apoptosis-inducing C1D protein
55. Recently integrated human Alu repeats: Finding needles in the haystack
56. Potential gene conversion and source genes for recently integrated Alu elements
57. Non-traditional Alu evolution and primate genomic diversity
58. Alu insertion polymorphisms for the study of human genomic diversity
59. DNA sequencing with chain-terminating inhibitors
60. A polymorphic L1 retroposon insertion in the centromere of the human Y chromosome
61. Many human L1 elements are capable of retrotransposition
62. Reading between the LINEs: Human genomic variation induced by LINE-1 retrotransposition
63. Unit-length LINE-1 transcripts in human teratocarcinoma cells
64. Interspersed repeats and other mementos of transposable elements in mammalian genomes
65. Ancestral, mammalian-wide subfamilies of LINE-1 repetitive sequences
66. Alu insertion polymorphisms and human evolution: Evidence for a larger population size in Africa
67. Retrotransposon reverse-transcriptase-mediated repair of chromosomal breaks
68. A double-strand break in a chromosomal LINE element can be repaired by gene conversion with various endogenous LINE elements in mouse cells
69. Apolipoprotein(a) gene enhancer resides within a LINE element