Erythromycin, roxithromycin, and clarithromycin: Use of slow-binding kinetics to compare their in vitro interaction with a bacterial ribosomal complex active in peptide bond formation

Molecular Pharmacology

Volumn 63, Issue 3, 2003, Pages 617-623

  Dinos, George P ^a   Connell, Sean R ^b,c   Nierhaus, Knud H ^b   Kalpaxis, Dimitrios L ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^c UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

70S RIBOSOME PROTEIN; ANTIBIOTIC AGENT; BACTERIAL RNA; CLARITHROMYCIN; DIMETHYL SULFATE; ERYTHROMYCIN; MACROLIDE; PUROMYCIN; RIBOSOME PROTEIN; ROXITHROMYCIN; TYLOSIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CHEMICAL MODIFICATION; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG STRUCTURE; ESCHERICHIA COLI; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STRUCTURE ANALYSIS; TRANSLATION REGULATION;

ANTI-BACTERIAL AGENTS; BACTERIA; CLARITHROMYCIN; ERYTHROMYCIN; KINETICS; RIBOSOMES; ROXITHROMYCIN;

EID: 0344406768     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.63.3.617     Document Type: Article

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