Thymine-rich single-stranded DNA activates Mcm4/6/7 helicase on Y-fork and bubble-like substrates

EMBO Journal

Volumn 22, Issue 22, 2003, Pages 6148-6160

  You, Zhiying ^a   Ishimi, Yukio ^b   Mizuno, Takeshi ^c,d   Sugasawa, Kaoru ^c,d   Hanaoka, Fumio ^c,d,e   Masai, Hisao ^a  

^a TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^b MITSUBISHI KAGAKU INSTITUTE OF LIFE SCIENCES   (Japan)

^c INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e OSAKA UNIVERSITY   (Japan)

Author keywords

Initiation of DNA replication; Mcm helicase; Replication bubble or fork; Replication origin; Thymine stretch

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ENZYME ACTIVATOR; GUANINE; HELICASE; LAMIN B; MINICHROMOSOME MAINTENANCE PROTEIN 4 6 7 COMPLEX; SINGLE STRANDED DNA; THYMINE; UNCLASSIFIED DRUG;

ARTICLE; CHROMATIN; DNA REPLICATION; DNA SEQUENCE; DNA STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE CLUSTER; GENOME; MAMMAL; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; TRANSCRIPTION INITIATION SITE;

ADENOSINE TRIPHOSPHATASES; CELL CYCLE PROTEINS; DNA HELICASES; DNA REPLICATION; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; HUMANS; LAMIN TYPE B; NUCLEAR PROTEINS; REPLICATION ORIGIN; THYMINE;

EUKARYOTA; MAMMALIA;

EID: 0344011592     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg576     Document Type: Article

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