Structure - Activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine

Bioorganic and Medicinal Chemistry

Volumn 9, Issue 5, 2001, Pages 1185-1195

  Le, Van Duc ^a   Mak, Chi Ching ^a   Lin, Ying Chuan ^b   Elder, John H ^b   Wong, Chi Huey ^a  

^a Dept Chem Skaggs Inst Chem Biol ^*  (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,5 DIMETHYL 1,3 THIAZOLIDINE 4 CABONYL; ALLOPHENYLNORSTATINE; AMINO ACID; CARBONYL DERIVATIVE; CARBOXYL GROUP; FIV PROTEASE INHIBITOR; HYDROXYMETHYLCARBOXAMINE ISOTERE; PROTEINASE INHIBITOR; STATINE DERIVATIVE; TL 3; UNCLASSIFIED DRUG; VLE 776;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; NONHUMAN; STRUCTURE ACTIVITY RELATION; VIRUS MUTANT;

ASPARTIC ENDOPEPTIDASES; DRUG RESISTANCE; HIV PROTEASE; HIV PROTEASE INHIBITORS; INHIBITORY CONCENTRATION 50; MUTAGENESIS; OLIGONUCLEOTIDES; PHENYLBUTYRATES; PROTEASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 0343844163     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00346-1     Document Type: Article

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