Cyclic HIV protease inhibitors capable of displacing the active site structural water molecule

Drug Discovery Today

Volumn 2, Issue 1, 1997, Pages 6-18

  De Lucca, G V ^a   Erickson Viitanen, S ^a   Lam, P Y S ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXY 6 (1 ETHYL 2 PHENYLETHYL) 3 (1 PHENYLPROPYL) 2 PYRONE; 4,7 DIBENZYL 2,3,4,5,6,7 HEXAHYDRO 5,6 DIHYDROXY 1,3 BIS[4 (HYDROXYMETHYL)BENZYL] 2H 1,3 DIAZEPIN 2 ONE; AMPRENAVIR; INDINAVIR; MOZENAVIR; NELFINAVIR; PROTEINASE INHIBITOR; PYRIMIDINONE DERIVATIVE; RITONAVIR; SAQUINAVIR; U 103017; UNCLASSIFIED DRUG; XM 311;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; BIOAVAILABILITY; CHEMICAL MODIFICATION; CONFORMATION; DRUG CONFORMATION; DRUG DESIGN; DRUG DEVELOPMENT; DRUG STRUCTURE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; ORAL DRUG ADMINISTRATION; REVIEW; STEREOCHEMISTRY;

EID: 0030811307     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(96)10048-9     Document Type: Review

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