Recruitment of TATA-binding protein-TAF(I) complex SL1 to the human ribosomal DNA promoter is mediated by the carboxy-terminal activation domain of upstream binding factor (UBF) and is regulated by UBF phosphorylation

Molecular and Cellular Biology

Volumn 19, Issue 4, 1999, Pages 2872-2879

  Tuan, Joann C ^a   Zhai, Weiguo ^a   Comai, Lucio ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; DEOXYRIBONUCLEASE I; DNA DIRECTED RNA POLYMERASE; RIBOSOME DNA; RIBOSOME RNA; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DEPHOSPHORYLATION; DNA FOOTPRINTING; HUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

EID: 0032936298     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.19.4.2872     Document Type: Article

References (39)

1. Beckmann, H., J. L. Chen, T. O'Brien, and R. Tijan. 1995. Coactivator and promoter-selective properties of RNA polymerase I TAFs. Science 270: 1506-1509.
2. Bell, S. P., R. M. Learned, H.-M. Jantzen, and R. Tijan. 1988. Functional cooperativity between transcription factors UBF1 and SL1 mediates human ribosomal RNA synthesis. Science 241:1192-1197.
3. Bell, S. P., C. S. Pikaard, R. H. Reeder, and R. Tijan. 1989. Molecular mechanisms governing species-specific transcription of ribosomal RNA. Cell 59:489-497.
4. Cavanaugh, A. H., W. M. Hempel, L., J. Taylor, V. Rogalsky, G. Todorov, and L. I. Rothblum. 1995. Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product. Nature 374:177-180.
5. Cavanaugh, A. H., and E. A. Thompson. 1986. Hormonal regulation of transcription of rDNA. J. Biol. Chem. 261:12738-12744.
6. Comai, L., N. Tanese, and R. Tijan. 1992. The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1. Cell 68:965-976.
7. Comai, L., J. C. B. M. Zomerdijk, H. Beckmann, S. Zhou, A. Admon, and R. Tijan. 1994. Reconstitution of transcription factor SL1: exclusive binding of TBP by SL1 or TFIID subunits. Science 266:1966-1972.
8. Gebrane-Younes, J., N. Fomproix, and D. Hernandez-Verdun. 1997. When rDNA transcription is arrested during mitosis, UBF is still associated with non-condensed rDNA. J. Cell Sci. 110:2429-2440.
9. Grummt, I., A. V. Smith, and F. Grummt. 1976. Amino acid starvation affects the initiation frequency of nucleolar RNA polymerase. Cell 7:439-445.
10. Gu, W., X.-L. Shi, and R. Roeder. 1997. Synergistic activation of transcription by CBP and p53. Nature 387:819-822.
11. Haltiner, M. M., S. T. Smale, and R. Tijan. 1986. Two distinct promoter elements in the human rRNA gene identified by linker scanning mutagenesis. Mol. Cell. Biol. 6:227-235.
12. Hammond, L. M., and H. L. Bowman. 1988. Insulin stimulates the translation of ribosomal proteins and the transcription of rRNA in mouse myoblast. J. Biol. Chem. 263:17785-17791.
13. Hempel, W. H., A. H. Cavanaugh, R. D. Hannan, L. Taylor, and L. I. Rothblum. 1996. The species-specific RNA polymerase I transcription factor SL-1 binds to upstream binding factor. Mol. Cell. Biol. 16:557-563.
14. Hershey, J. C., M. Hautmann, M. M. Thompson, L., I. Rothblum, T. A. J. Haystead, and G. K. Owens. 1995. Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor. J. Biol. Chem. 270:25096-25101.
15. Hunter, T., and M. Karin. 1992. The regulation of transcription through phosphorylation. Cell 70:375-387.
16. Jacob, S. T. 1995. Regulation of ribosomal gene transcription. Biochem. J. 306:617-626.
17. Jantzen, H.-M., A. Admon, S. P. Bell, and R. Tijan. 1990. Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins. Nature 344:830-836.
18. Jantzen, H.-M., A. M. Chow, D. S. King, and R. Tijan. 1992. Multiple domains of the RNA polymerase I activator hUBF interact with the TATA-binding protein complex hSL1 to mediate transcription. Genes Dev. 6:1950-1963.
19. Kwon, H., and M. Green. 1994. The RNA polymerase I transcription factor, upstream binding factor, interacts directly with the TATA box-binding protein. J. Biol. Chem. 269:30140-30146.
20. Learned, R. M., S. Cordes, and R. Tijan. 1985. Purification and characterization of a transcription factor that confers promoter specificity to human RNA polymerase I. Mol. Cell. Biol. 5:1358-1369.
21. Learned, R. M., T. K. Learned, M. M. Haltiner, and R. Tijan. 1986. Human rRNA transcription is modulated by the coordinate binding of two factors to an upstream control element. Cell 45:847-857.
22. Lee, T. I., and R. A. Young. 1998. Regulation of gene expression by TBP-associated proteins. Genes Dev. 12:1398-1408.
23. McStay, B., M. W. Frazier, and R. H. Reeder. 1991. xUBF contains a novel dimerization domain essential for RNA polymerase I transcription. Genes Dev. 5:1957-1968.
24. Mishima, Y. M., T. Matsui, and M. Muramatsu. 1979. The mechanism of decrease in nucleolar RNA synthesis by protein synthesis inhibition. J. Biochem. 85:807-818.
25. Moss, T., and V. Y. Stefanovsky. 1995. Promotion and regulation of ribosomal transcription in eukaryotes by RNA polymerase I. Prog. Nucleic Acids Res. Mol. Biol. 50:25-66.
26. O'Mahony, D. J., S. D. Smith, W. Xie, and L. I. Rothblum. 1992. Analysis of the phosphorylation, DNA-binding and dimerization properties of the RNA polymerase I transcription factors UBF1 and UBF2. Nucleic Acids Res. 20: 1301-1308.
27. O'Mahony, D. J., W. Xie, S. D. Smith, H. A. Singer, and L. I. Rothblum. 1992. Differential phosphorylation and localization of the transcription factor UBF in viva in response to serum deprivation. J. Biol. Chem 267:35-38.
28. Pape, L. K., J. J. Windle, and B. Sollner-Webb. 1990. Half helical turn spacing changes convert a frog into a mouse rDNA promoter: a distant upstream domain determines the helix face of the initiation site. Genes Dev. 4:52-62.
29. Paule, M. R. 1998. Transcription of ribosomal RNA genes by eukaryotic RNA polymerase I. Springer-Verlae, Inc., New York, N.Y.
30. Paule, M. R., C. T. Iida, P. J. Perna, G. H. Harris, D. A. Knoll, and J. M. D'Alessio. 1984. In vitro evidence that eukaryotic ribosomal RNA transcription is regulated by modification of RNA polymerase I. Nucleic Acids Res. 12:8161-8180.
31. Roussel, P., C. Andre, L. Comai, and D. Hernandez-Verdun. 1996. The rDNA transcription machinery is stabilized as initiation complex during mitosis in active NORs and absent in inactive NORs. J. Cell Biol. 133:235-246.
32. Rudloff, U., D. Eberhard, L. Tora, H. Stunnenberg, and I. Grummt. 1994 TBP associated factors interact with DNA and govern species specificity of RNA polymerase I transcription. EMBO J. 13:2611-2616.
33. Schnapp, G., F. Santori, C. Carles, M. Riva, and I. Grummt, 1994. The HMG box-containing nucleolar transcription factor UBF interacts with a specific subunit of RNA polymerase I. EMBO J. 13:190-199.
34. Treisman, R. 1996. Regulation of transcription by MAP kinase cascade. Curr. Opin. Cell Biol. 8:205-215.
35. Verrijzer, C. P., and R. Tijan. 1996. TAFs mediate transcriptional activation and promoter selectivity. Trends Biochem. Sci. 21:338-342.
36. Voit, R., A. Kuhn, E. E. Sander, and I. Grummt. 1995 Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF. Nucleic Acids Res. 23:2593-2599.
37. Voit, R., A. Schnapp, A. Kuhn, H. Rosenbauer, P. Hirschmann, H. G. Stunnenberg, and I. Grummt. 1992. The nucleolar transcription factor mUBF is phosphorylated by casein kinase II in the C-terminal hyperacidic tail which is essential for transactivation. EMBO J. 11:2211-2218.
38. Zhai, W., and L. Comai. Unpublished observation.
39. 1 complex SL1 and coactivates ribosomal RNA transcription. Genes Dev. 11:1605-1617.