Sequence, structure and energetic determinants of phosphopeptide selectivity of SH2 domains

Journal of Molecular Biology

Volumn 334, Issue 4, 2003, Pages 823-841

  Sheinerman, Felix B ^a,b   Al Lazikani, Bissan ^a,c   Honig, Barry ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b SANOFI   (France)

^c Inpharmatica Ltd   (United Kingdom)

Author keywords

Binding site signature; Binding specificity; Chemogenomics; Continuum electrostatics; Multiple structure and sequence alignment

Indexed keywords

PHOSPHOPEPTIDE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CORRELATION ANALYSIS; ELECTRICITY; ENERGY; HYDROPHOBICITY; MOLECULAR INTERACTION; PREDICTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; STEREOCHEMISTRY;

EID: 0242551544     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.09.075     Document Type: Article

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