-
1
-
-
0034096992
-
Recent advances in the treatment of acute leukemia
-
Berman E. Recent advances in the treatment of acute leukemia. Curr Opin Hematol. 2000;4:205-211.
-
(2000)
Curr Opin Hematol
, vol.4
, pp. 205-211
-
-
Berman, E.1
-
2
-
-
0034090052
-
New strategies for the treatment of acute myelogenous leukemia: Differentiation induction-present use and future possibilities
-
Bruservd O, Gjertsen BT. New strategies for the treatment of acute myelogenous leukemia: differentiation induction-present use and future possibilities. Stem Cells. 2000;18:157-165.
-
(2000)
Stem Cells
, vol.18
, pp. 157-165
-
-
Bruservd, O.1
Gjertsen, B.T.2
-
3
-
-
0030729964
-
Therapeutic options in the management of acute myelogenous leukemia in adults
-
Saez RA, Therapeutic options in the management of acute myelogenous leukemia in adults. Cancer Control. 1997;4:399-406.
-
(1997)
Cancer Control
, vol.4
, pp. 399-406
-
-
Saez, R.A.1
-
4
-
-
0033830630
-
New strategies in the treatment of acute myelogenous leukemia: Mobilization and transplantation of autologous peripheral stem cells in adult patients
-
Bruservd O, Tjonnfijord G, Gjertjen BT, Foss B, Ernst P. New strategies in the treatment of acute myelogenous leukemia: mobilization and transplantation of autologous peripheral stem cells in adult patients. Stem Cells. 2000;18:343-351.
-
(2000)
Stem Cells
, vol.18
, pp. 343-351
-
-
Bruservd, O.1
Tjonnfijord, G.2
Gjertjen, B.T.3
Foss, B.4
Ernst, P.5
-
5
-
-
12944281160
-
High dose cytosine arabinoside and daunorubicin induction therapy for adult patients with de novo non M3 acute myelogenous leukemia: Impact of cytogenetics on achieving a complete remission
-
Stein AS, O'Connell MR, Slovak ML, et al. High dose cytosine arabinoside and daunorubicin induction therapy for adult patients with de novo non M3 acute myelogenous leukemia: impact of cytogenetics on achieving a complete remission. Leukemia. 2000;14:1191-1196.
-
(2000)
Leukemia
, vol.14
, pp. 1191-1196
-
-
Stein, A.S.1
O'Connell, M.R.2
Slovak, M.L.3
-
6
-
-
0026040363
-
A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients
-
Chen ZX, Xue YQ, Zhang R, et al. A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients. Blood. 1991;78:1413-1419.
-
(1991)
Blood
, vol.78
, pp. 1413-1419
-
-
Chen, Z.X.1
Xue, Y.Q.2
Zhang, R.3
-
7
-
-
0025201879
-
All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia, I: Clinical results
-
Castaigne S, Chomienne C, Daniel MT, et al. All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia, I: clinical results. Blood. 1990;76:1704-1709.
-
(1990)
Blood
, vol.76
, pp. 1704-1709
-
-
Castaigne, S.1
Chomienne, C.2
Daniel, M.T.3
-
8
-
-
0025882306
-
Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid)
-
Warrell RP, Frankel SR, Miller WH, et al. Differentiation therapy of acute promyelocytic leukemia with tretinoin (all-trans-retinoic acid). N Engl J Med. 1991;324:1385-1393.
-
(1991)
N Engl J Med
, vol.324
, pp. 1385-1393
-
-
Warrell, R.P.1
Frankel, S.R.2
Miller, W.H.3
-
9
-
-
0000530241
-
The retinoid receptors
-
Sporn MB, Roberts AB, Goodman DS, eds. New York, NY: Raven Press
-
Mangelsdorf DJ, Umesono K, Evans RM. The retinoid receptors. In: Sporn MB, Roberts AB, Goodman DS, eds. The Retinoids Biology, Chemistry and Medicine. New York, NY: Raven Press; 1994:319-350.
-
(1994)
The Retinoids Biology, Chemistry and Medicine
, pp. 319-350
-
-
Mangelsdorf, D.J.1
Umesono, K.2
Evans, R.M.3
-
10
-
-
0028176437
-
The PML-RARα gene product of the t(15:17) translocation inhibits retinoic acid-induced granulocyte differentiation and mediated transactivation in human myeloid cells
-
Rousselot P, Hardas B, Patel A, et al. The PML-RARα gene product of the t(15:17) translocation inhibits retinoic acid-induced granulocyte differentiation and mediated transactivation in human myeloid cells. Oncogene. 1994;9:545-551.
-
(1994)
Oncogene
, vol.9
, pp. 545-551
-
-
Rousselot, P.1
Hardas, B.2
Patel, A.3
-
12
-
-
0027362933
-
The PML retinoic acid receptor α translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1
-
Doucas V, Brocues JP, Yaniv M, de The H, Dejean A. The PML retinoic acid receptor α translocation converts the receptor from an inhibitor to a retinoic acid-dependent activator of transcription factor AP-1. Proc Natl Acad Sci U S A. 1993;90:9345-9349.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9345-9349
-
-
Doucas, V.1
Brocues, J.P.2
Yaniv, M.3
De The, H.4
Dejean, A.5
-
13
-
-
0028158682
-
Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells
-
Weiss K, Rambaud S, Lavan K. Retinoic acid regulates aberrant nuclear localization of PML-RARα in acute promyelocytic leukemia cells. Cell. 1994;76:345-354.
-
(1994)
Cell
, vol.76
, pp. 345-354
-
-
Weiss, K.1
Rambaud, S.2
Lavan, K.3
-
14
-
-
0033561797
-
Deconstructing a disease: RARα its fusion partners and their roles in the pathogenesis of acute promyelocytic leukemia
-
Melnick A, Licht JD. Deconstructing a disease: RARα its fusion partners and their roles in the pathogenesis of acute promyelocytic leukemia. Blood. 1999;93:3167-3215.
-
(1999)
Blood
, vol.93
, pp. 3167-3215
-
-
Melnick, A.1
Licht, J.D.2
-
15
-
-
0019407488
-
Terminal differentiation of human promyelocytic cells in primary culture in response to retinoic acid
-
Breitman TR, Collins SJ, Keene BR. Terminal differentiation of human promyelocytic cells in primary culture in response to retinoic acid. Blood. 1981;57:1000-1004.
-
(1981)
Blood
, vol.57
, pp. 1000-1004
-
-
Breitman, T.R.1
Collins, S.J.2
Keene, B.R.3
-
16
-
-
0022135739
-
Proposed criteria for the classification of acute myeloid leukemia: A report of the French-American-British Group
-
Bennett JB, Catovsky D, Daniel MT, et al. Proposed criteria for the classification of acute myeloid leukemia: a report of the French-American-British Group. Ann Intern Med. 1985;103:620-625.
-
(1985)
Ann Intern Med
, vol.103
, pp. 620-625
-
-
Bennett, J.B.1
Catovsky, D.2
Daniel, M.T.3
-
17
-
-
0028983107
-
p53 independent G0/G1 arrest and apoptosis induced by a novel retinoid in breast cancer cells
-
Shao ZM, Dawson MI, Li XS, et al. p53 independent G0/G1 arrest and apoptosis induced by a novel retinoid in breast cancer cells. Oncogene. 1995;11:493-504.
-
(1995)
Oncogene
, vol.11
, pp. 493-504
-
-
Shao, Z.M.1
Dawson, M.I.2
Li, X.S.3
-
18
-
-
12644302209
-
Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo
-
Schadendorf D, Kern MA, Phal HL, et al. Treatment of melanoma cells with the synthetic retinoid CD437 induces apoptosis via activation of AP-1 in vitro, and causes growth inhibition in xenografts in vivo. J Cell Biol. 1996;135:1889-1898.
-
(1996)
J Cell Biol
, vol.135
, pp. 1889-1898
-
-
Schadendorf, D.1
Kern, M.A.2
Phal, H.L.3
-
19
-
-
0031018031
-
Rapid induction of apoptosis in human C33A cervical carcinoma cells by the synthetic retinoid 6-[3-(1-adamantyl)hydroxyphenyl]-2-naphtalenecarboxylic acid (CD437)
-
Oridate N, Higuchi M, Suzuki S, Shroot B, Hong WK, Lotan R. Rapid induction of apoptosis in human C33A cervical carcinoma cells by the synthetic retinoid 6-[3-(1-adamantyl)hydroxyphenyl]-2-naphtalenecarboxylic acid (CD437). Int J Cancer. 1997;70:484-487.
-
(1997)
Int J Cancer
, vol.70
, pp. 484-487
-
-
Oridate, N.1
Higuchi, M.2
Suzuki, S.3
Shroot, B.4
Hong, W.K.5
Lotan, R.6
-
20
-
-
0030780951
-
Induction of apoptosis in human non-small cell lung carcinoma cells by the synthetic retinoid CD437
-
Sun SY, Yue P, Shroot B, Hong WK, Lotan R. Induction of apoptosis in human non-small cell lung carcinoma cells by the synthetic retinoid CD437. J Cell Physiol. 1997;173:279-284.
-
(1997)
J Cell Physiol
, vol.173
, pp. 279-284
-
-
Sun, S.Y.1
Yue, P.2
Shroot, B.3
Hong, W.K.4
Lotan, R.5
-
21
-
-
0032011418
-
Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma cells
-
Adachi H, Preston G, Harvat B, Dawson MI, Jetten AM. Inhibition of cell proliferation and induction of apoptosis by the retinoid AHPN in human lung carcinoma cells. Am J Respir Cell Mol Biol. 1998;18:323-333.
-
(1998)
Am J Respir Cell Mol Biol
, vol.18
, pp. 323-333
-
-
Adachi, H.1
Preston, G.2
Harvat, B.3
Dawson, M.I.4
Jetten, A.M.5
-
22
-
-
0027129816
-
Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptorγ
-
Bernard BA, Bernardon JM, Delesclose C, et al. Identification of synthetic retinoids with selectivity for human nuclear retinoic acid receptorγ. Biochem Biophys Res Commun. 1992;186:977-983.
-
(1992)
Biochem Biophys Res Commun
, vol.186
, pp. 977-983
-
-
Bernard, B.A.1
Bernardon, J.M.2
Delesclose, C.3
-
23
-
-
0031149494
-
Effects of receptor class- and subtype-selective retinoids and an apoptosis-inducing retinoid on the adherent growth of the NIH:OVCAR-3 ovarian cell line in culture
-
Chao WR, Hobbs PD, Jong L, et al. Effects of receptor class- and subtype-selective retinoids and an apoptosis-inducing retinoid on the adherent growth of the NIH:OVCAR-3 ovarian cell line in culture. Cancer Lett. 1997;115:1-7.
-
(1997)
Cancer Lett
, vol.115
, pp. 1-7
-
-
Chao, W.R.1
Hobbs, P.D.2
Jong, L.3
-
24
-
-
0033579930
-
A selective retinoid with high activity against androgen-resistant prostate cancer cell type
-
Lu XP, Fanjul A, Picard N, Shroot B, Pfahl M. A selective retinoid with high activity against androgen-resistant prostate cancer cell type. Int J Cancer. 1999;80:272-278.
-
(1999)
Int J Cancer
, vol.80
, pp. 272-278
-
-
Lu, X.P.1
Fanjul, A.2
Picard, N.3
Shroot, B.4
Pfahl, M.5
-
25
-
-
0033842280
-
Induction of apoptosis in ovarian cells by AHPN/CD437 is mediated by retinoid receptors
-
Holmes WF, Dawson MI, Soprano D, Soprano KJ. Induction of apoptosis in ovarian cells by AHPN/CD437 is mediated by retinoid receptors. J Cell Physiol. 2000;185:61-67.
-
(2000)
J Cell Physiol
, vol.185
, pp. 61-67
-
-
Holmes, W.F.1
Dawson, M.I.2
Soprano, D.3
Soprano, K.J.4
-
26
-
-
0031008522
-
Retinoid induced apoptosis in leukemia cells through a retinoic acid nuclear receptor independent pathway
-
Hsu CA, Rishi AK, Li XS, et al. Retinoid induced apoptosis in leukemia cells through a retinoic acid nuclear receptor independent pathway. Blood. 1997;89:4470-4479.
-
(1997)
Blood
, vol.89
, pp. 4470-4479
-
-
Hsu, C.A.1
Rishi, A.K.2
Li, X.S.3
-
27
-
-
0037108561
-
Induction of apoptosis of human B-CLL and ALL cell by a novel retinoid and its non-retinoidal analog
-
Zhang Y, Dawson MI, Mohammad R, et al. Induction of apoptosis of human B-CLL and ALL cell by a novel retinoid and its non-retinoidal analog. Blood. 2002;100:2917-2925.
-
(2002)
Blood
, vol.100
, pp. 2917-2925
-
-
Zhang, Y.1
Dawson, M.I.2
Mohammad, R.3
-
28
-
-
0028332160
-
Cytokine-dependent engraftment of human myeloid leukemia cell lines in immunosuppressed nude mice
-
Thacker DJ, Hogge DE. Cytokine-dependent engraftment of human myeloid leukemia cell lines in immunosuppressed nude mice. Leukemia. 1994;8:871-877.
-
(1994)
Leukemia
, vol.8
, pp. 871-877
-
-
Thacker, D.J.1
Hogge, D.E.2
-
29
-
-
0018255012
-
Acute myelogenous leukemia: A human cell line responsive to colony stimulating factor
-
Koeffler HP, Golde DW. Acute myelogenous leukemia: a human cell line responsive to colony stimulating factor. Science. 1978;200:1153-1154.
-
(1978)
Science
, vol.200
, pp. 1153-1154
-
-
Koeffler, H.P.1
Golde, D.W.2
-
30
-
-
0026808722
-
Retinoic acid-resistant HL-60R cells harbor a point mutation in the retinoic acid receptor ligand-binding domain that confers dominant negative activity
-
Robertson KA, Emami B, Collins SJ. Retinoic acid-resistant HL-60R cells harbor a point mutation in the retinoic acid receptor ligand-binding domain that confers dominant negative activity. Blood. 1992;1885-1889.
-
(1992)
Blood
, pp. 1885-1889
-
-
Robertson, K.A.1
Emami, B.2
Collins, S.J.3
-
31
-
-
0029063607
-
Activation of retinoid X receptors induces apoptosis in HL-60 cell lines
-
Nagy L, Thomazy VA, Shipley GL, et al. Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Mol Cell Biol. 1995;15:3540-3551.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3540-3551
-
-
Nagy, L.1
Thomazy, V.A.2
Shipley, G.L.3
-
32
-
-
0028063456
-
Mechanism of regulation of WAF1/CIP1 gene expression in human breast carcinoma: Role of p53-dependent and independent signal transduction pathways
-
Sheikh MS, Li XS, Chen JC, Shao ZM, Ordonez JV, Fontana JA. Mechanism of regulation of WAF1/CIP1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways. Oncogene. 1994;9:3407-3415.
-
(1994)
Oncogene
, vol.9
, pp. 3407-3415
-
-
Sheikh, M.S.1
Li, X.S.2
Chen, J.C.3
Shao, Z.M.4
Ordonez, J.V.5
Fontana, J.A.6
-
33
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavreli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol. 1992;119:493-501.
-
(1992)
J Cell Biol
, vol.119
, pp. 493-501
-
-
Gavreli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
34
-
-
0029099358
-
Involvement of NAD poly(ADP-ribose) metabolism in p53 regulation and its consequences
-
Whitacre CM, Hashimato T, Tsai ML, Chatterjee S, Berger SL, Berger NA. Involvement of NAD poly(ADP-ribose) metabolism in p53 regulation and its consequences. Cancer Res. 1995;55:3697-3701.
-
(1995)
Cancer Res
, vol.55
, pp. 3697-3701
-
-
Whitacre, C.M.1
Hashimato, T.2
Tsai, M.L.3
Chatterjee, S.4
Berger, S.L.5
Berger, N.A.6
-
35
-
-
0016800607
-
Flow cytofluorimetry: Discrimination between single cells and cell aggregates by direct size measurements
-
Sharpless T, Traganos F, Darzynkiewicz T, Melamed MR. Flow cytofluorimetry: discrimination between single cells and cell aggregates by direct size measurements. Acta Cytologica. 1975;19:577-581.
-
(1975)
Acta Cytologica
, vol.19
, pp. 577-581
-
-
Sharpless, T.1
Traganos, F.2
Darzynkiewicz, T.3
Melamed, M.R.4
-
36
-
-
0028147434
-
In vivo-in vitro correlation of myelotoxicity of 9-methoxypyrazoloacidine (NSC-366140, PD115934) to myeloid and erythroid hematopoietic progenitors from human, murine and canine marrow
-
Parchment RE, Volpe DA, LoRusso PM, Erickson-Miller CL, Murphy MJ. In vivo-in vitro correlation of myelotoxicity of 9-methoxypyrazoloacidine (NSC-366140, PD115934) to myeloid and erythroid hematopoietic progenitors from human, murine and canine marrow. J Natl Cancer Inst. 1994;86:273-280.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 273-280
-
-
Parchment, R.E.1
Volpe, D.A.2
LoRusso, P.M.3
Erickson-Miller, C.L.4
Murphy, M.J.5
-
37
-
-
0032847951
-
Preclinical efficacy of thioxanthone SR-271425 against transplanted solid tumors of mouse and human origin
-
Corbett TH, Panchapor C, Polin L, et al. Preclinical efficacy of thioxanthone SR-271425 against transplanted solid tumors of mouse and human origin. Invest New Drugs. 1999;17:17-27.
-
(1999)
Invest New Drugs
, vol.17
, pp. 17-27
-
-
Corbett, T.H.1
Panchapor, C.2
Polin, L.3
-
38
-
-
0038208665
-
In vivo tumor response end points
-
Teicher B, ed. Totowa, NJ: Humana Press
-
Teicher BA. In vivo tumor response end points. In: Tumor Models in Cancer Research. Teicher B, ed. Totowa, NJ: Humana Press;2001:593-616.
-
(2001)
Tumor Models in Cancer Research
, pp. 593-616
-
-
Teicher, B.A.1
-
39
-
-
0028862519
-
Tumor models and the discovery and secondary evaluation of solid tumor active agents
-
Corbett T, Valeriote F, LoRusso P, et al. Tumor models and the discovery and secondary evaluation of solid tumor active agents. Int J Pharmacognosy. 1995(suppl);33:102-122.
-
(1995)
Int J Pharmacognosy
, vol.33
, Issue.SUPPL.
, pp. 102-122
-
-
Corbett, T.1
Valeriote, F.2
LoRusso, P.3
-
40
-
-
15644364847
-
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes
-
Woo M, Hakem R, Soengas MS, et al. Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes. Genes Dev. 1998;12:806-819.
-
(1998)
Genes Dev
, vol.12
, pp. 806-819
-
-
Woo, M.1
Hakem, R.2
Soengas, M.S.3
-
41
-
-
0033575255
-
Suicidal tendencies: Apoptotic cell death by caspase family proteases
-
Wolf BB, Green DR. Suicidal tendencies: apoptotic cell death by caspase family proteases. J Biol Chem. 1999;274:20049-20052.
-
(1999)
J Biol Chem
, vol.274
, pp. 20049-20052
-
-
Wolf, B.B.1
Green, D.R.2
-
42
-
-
0032549670
-
Caspase-dependent cleavage of signaling proteins during apoptosis: A turn-off mechanism for anti-apoptotic signals
-
Widmann C, Gibson S, Johnson CL. Caspase-dependent cleavage of signaling proteins during apoptosis: a turn-off mechanism for anti-apoptotic signals. J Biol Chem. 1998;273:7141-7147.
-
(1998)
J Biol Chem
, vol.273
, pp. 7141-7147
-
-
Widmann, C.1
Gibson, S.2
Johnson, C.L.3
-
44
-
-
0028102478
-
Cleavage of poly(ADP-ribose) polymerase by a protease with properties like ICE
-
Lazebnik YA, Kaufman SH, Desnoyers S, Poirier GG, Earnshaw WC. Cleavage of poly(ADP-ribose) polymerase by a protease with properties like ICE. Nature. 1994;371:346-347.
-
(1994)
Nature
, vol.371
, pp. 346-347
-
-
Lazebnik, Y.A.1
Kaufman, S.H.2
Desnoyers, S.3
Poirier, G.G.4
Earnshaw, W.C.5
-
45
-
-
0035895540
-
Apoptotic molecular machinery: Vastly increased complexity in vertebrates revealed by genome comparisons
-
Aravind L, Dixit VM, Koonin EV. Apoptotic molecular machinery: vastly increased complexity in vertebrates revealed by genome comparisons. Science. 2001;291:1279-1284.
-
(2001)
Science
, vol.291
, pp. 1279-1284
-
-
Aravind, L.1
Dixit, V.M.2
Koonin, E.V.3
-
46
-
-
0033179760
-
Bcl-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnel JM, Korsmeyer SJ. Bcl-2 family members and the mitochondria in apoptosis. Genes Dev. 1999;13:1899-1911.
-
(1999)
Genes Dev
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnel, J.M.2
Korsmeyer, S.J.3
-
47
-
-
0029978058
-
Drug-induced apoptosis in B-cell chronic lymphocytic leukemia: Relationship between p53 gene mutation and bcl-2/ bax proteins in drug resistance
-
Thomas A, El Rouby S, Reed JC, Krajewski S, Potmesil M, Newcomb, EW. Drug-induced apoptosis in B-cell chronic lymphocytic leukemia: relationship between p53 gene mutation and bcl-2/ bax proteins in drug resistance. Oncogene. 1996;12:1055-1062.
-
(1996)
Oncogene
, vol.12
, pp. 1055-1062
-
-
Thomas, A.1
El Rouby, S.2
Reed, J.C.3
Krajewski, S.4
Potmesil, M.5
Newcomb, E.W.6
-
48
-
-
0027239823
-
Bcl-2 gene hypomethylation and high level expression in B-cell chronic lymphocytic leukemia
-
Hanada M, Delia D, Aiello A, Stadmauer E, Reed JC. Bcl-2 gene hypomethylation and high level expression in B-cell chronic lymphocytic leukemia. Blood. 1993;82:1820-1828.
-
(1993)
Blood
, vol.82
, pp. 1820-1828
-
-
Hanada, M.1
Delia, D.2
Aiello, A.3
Stadmauer, E.4
Reed, J.C.5
-
49
-
-
0031034078
-
Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions
-
Zhou P, Qian L, Kozopas KM, Craig RW. Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions. Blood. 1997;89:630-643.
-
(1997)
Blood
, vol.89
, pp. 630-643
-
-
Zhou, P.1
Qian, L.2
Kozopas, K.M.3
Craig, R.W.4
-
50
-
-
0027282044
-
Bcl-X, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
Boise LH, Garcia-Gonzalez M, Postema CE, et al. Bcl-X, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell. 1993;74:597-608.
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
Garcia-Gonzalez, M.2
Postema, C.E.3
-
51
-
-
0010832069
-
Acceleration of apoptotic death after cleavage of bcl-XL protein by caspase-3 like protease
-
Fujita N, Nagahashi A, Nagashima K, Rokudai S, Tsuruo T. Acceleration of apoptotic death after cleavage of bcl-XL protein by caspase-3 like protease. Oncogene. 1998;17:1293-1307.
-
(1998)
Oncogene
, vol.17
, pp. 1293-1307
-
-
Fujita, N.1
Nagahashi, A.2
Nagashima, K.3
Rokudai, S.4
Tsuruo, T.5
-
52
-
-
0034525423
-
Kinases: Positive and negative regulators of apoptosis
-
Franklin RA, McCubrey JA. Kinases: positive and negative regulators of apoptosis. Leukemia. 2000;14:2019-2034.
-
(2000)
Leukemia
, vol.14
, pp. 2019-2034
-
-
Franklin, R.A.1
McCubrey, J.A.2
-
53
-
-
0032541633
-
Anti-apoptotic versus pro-apoptotic signal transduction checkpoints and stop signs along the road to death
-
Jarpe MB, Widmann C, Knall C. Anti-apoptotic versus pro-apoptotic signal transduction checkpoints and stop signs along the road to death. Oncogene. 1998;17:1475-1482.
-
(1998)
Oncogene
, vol.17
, pp. 1475-1482
-
-
Jarpe, M.B.1
Widmann, C.2
Knall, C.3
-
54
-
-
0034671751
-
Requirement for ERK activation in cisplatinum-induced apoptosis
-
Wang X, Martindale JL, Holbrook NJ. Requirement for ERK activation in cisplatinum-induced apoptosis. J Biol Chem. 2000;275:39435-39443.
-
(2000)
J Biol Chem
, vol.275
, pp. 39435-39443
-
-
Wang, X.1
Martindale, J.L.2
Holbrook, N.J.3
-
55
-
-
0034607702
-
Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway
-
Tournier C, Hess P, Yang DD, et al. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science. 2000;288:870-874.
-
(2000)
Science
, vol.288
, pp. 870-874
-
-
Tournier, C.1
Hess, P.2
Yang, D.D.3
-
56
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell. 2000;103:239-252.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
57
-
-
0033602027
-
Activation of the p38 and JNK/SAPK mitogen activated protein kinase pathways during apoptosis mediated by a novel retinoid
-
Zhang Y, Hang Y, Dawson M, et al. Activation of the p38 and JNK/SAPK mitogen activated protein kinase pathways during apoptosis mediated by a novel retinoid. Exp Cell Res. 1999;247:233-240.
-
(1999)
Exp Cell Res
, vol.247
, pp. 233-240
-
-
Zhang, Y.1
Hang, Y.2
Dawson, M.3
-
58
-
-
0013898625
-
Myeloid leukemia C1498 as a screen for cancer chemotherapeutic agents
-
Bradner WT, Pindell MH. Myeloid leukemia C1498 as a screen for cancer chemotherapeutic agents. Cancer Res. 1966;26:375-390.
-
(1966)
Cancer Res
, vol.26
, pp. 375-390
-
-
Bradner, W.T.1
Pindell, M.H.2
-
59
-
-
0031800079
-
Predicting hematological toxicity (myelosuppression) of cytoxic drug therapy from in vitro tests
-
Parchment RE, Gordon M, Grieshaber CK, Volpe D, Ghielmini M. Predicting hematological toxicity (myelosuppression) of cytoxic drug therapy from in vitro tests. Ann Oncol. 1998;9:357-364.
-
(1998)
Ann Oncol
, vol.9
, pp. 357-364
-
-
Parchment, R.E.1
Gordon, M.2
Grieshaber, C.K.3
Volpe, D.4
Ghielmini, M.5
-
60
-
-
2642689658
-
Proteases to die for
-
Cryns Y, Yuan J. Proteases to die for. Genes Dev. 1998;12:1551-1570.
-
(1998)
Genes Dev
, vol.12
, pp. 1551-1570
-
-
Cryns, Y.1
Yuan, J.2
-
61
-
-
0031738682
-
Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma involves caspase-dependent and independent pathways
-
Adachi H, Adams A, Hughes FM, Zhang J, Cidlowski JA, Jetten AM. Induction of apoptosis by the novel retinoid AHPN in human T-cell lymphoma involves caspase-dependent and independent pathways. Cell Death Differ. 1998;5:973-983.
-
(1998)
Cell Death Differ
, vol.5
, pp. 973-983
-
-
Adachi, H.1
Adams, A.2
Hughes, F.M.3
Zhang, J.4
Cidlowski, J.A.5
Jetten, A.M.6
-
62
-
-
0033564118
-
Implication of p53 in growth arrest and apoptosis induced by the synthetic retinoid CD437 in human lung cancer cells
-
Sun SY, Yue P, Wu GS, et al. Implication of p53 in growth arrest and apoptosis induced by the synthetic retinoid CD437 in human lung cancer cells. Cancer Res. 1999;59:2829-2833.
-
(1999)
Cancer Res
, vol.59
, pp. 2829-2833
-
-
Sun, S.Y.1
Yue, P.2
Wu, G.S.3
-
63
-
-
0034671314
-
Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid (CD437) through up-regulation of TRAIL receptors in human lung cancer cells
-
Sun SY, Yue P, Hong WK, Lotan R. Augmentation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by the synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid (CD437) through up-regulation of TRAIL receptors in human lung cancer cells. Cancer Res. 2000;60:7149-7155.
-
(2000)
Cancer Res
, vol.60
, pp. 7149-7155
-
-
Sun, S.Y.1
Yue, P.2
Hong, W.K.3
Lotan, R.4
-
64
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4 participates in cytochrome c-dependent activation of caspase-3
-
Zou H, Henzel W, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED-4 participates in cytochrome c-dependent activation of caspase-3. Cell. 1997;90:405-413.
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
65
-
-
0028990125
-
Yama/CPP32β, a mammalian homolog of CED-3, is a CRM A-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M, Quan LT, O'Rourke KO, et al. Yama/CPP32β, a mammalian homolog of CED-3, is a CRM A-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 1995;81:801-809.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.O.3
-
66
-
-
0032481346
-
The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4
-
Huang DCS, Adams JM, Cory S. The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4. EMBO J. 1998;17:1029-1039.
-
(1998)
EMBO J
, vol.17
, pp. 1029-1039
-
-
Huang, D.C.S.1
Adams, J.M.2
Cory, S.3
-
67
-
-
0031930688
-
Modulation of cell death by Bcl-XL through caspase interaction
-
Clem RJ, Cheng EYH, Karp CL. Modulation of cell death by Bcl-XL through caspase interaction. Proc Natl Acad Sci U S A. 1998;95:554-559.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 554-559
-
-
Clem, R.J.1
Cheng, E.Y.H.2
Karp, C.L.3
-
68
-
-
0031015043
-
Fas activation of the p38 mitogen-activated protein kinase signaling pathway requires ICE/CED-3 family proteases
-
Juo P, Kuo, CJ, Reynolds SE, et al. Fas activation of the p38 mitogen-activated protein kinase signaling pathway requires ICE/CED-3 family proteases. Mol Cell. Biol. 1997;17:24-35.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 24-35
-
-
Juo, P.1
Kuo, C.J.2
Reynolds, S.E.3
-
69
-
-
0028880006
-
Opposing effects of ERK and JNK and p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK and p38 MAP kinases on apoptosis. Science. 1995;270:1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
70
-
-
0034647694
-
p38 mitogen-activated protein kinase regulates a novel caspase-independent pathway for the mitochondrial cytochrome C release in ultraviolet B radiation-induced apoptosis
-
Assefa Z, Vanteghem A, Garmyn M, et al. p38 mitogen-activated protein kinase regulates a novel caspase-independent pathway for the mitochondrial cytochrome C release in ultraviolet B radiation-induced apoptosis. J Biol Chem. 2000;275:21416-21421.
-
(2000)
J Biol Chem
, vol.275
, pp. 21416-21421
-
-
Assefa, Z.1
Vanteghem, A.2
Garmyn, M.3
-
71
-
-
0034737435
-
Activation of p38 and c-jun N terminal kinase pathways and inhibition of apoptosis by chelerythrine do not require inhibition of protein kinase C
-
Yu R, Mandelkar S, Tan, TH, Kong ANT, Activation of p38 and c-jun N terminal kinase pathways and inhibition of apoptosis by chelerythrine do not require inhibition of protein kinase C. J Biol Chem. 2000;275:9612-9619.
-
(2000)
J Biol Chem
, vol.275
, pp. 9612-9619
-
-
Yu, R.1
Mandelkar, S.2
Tan, T.H.3
Kong, A.N.T.4
-
72
-
-
0030759279
-
Kinase cascades regulating entry into apoptosis
-
Anderson P. Kinase cascades regulating entry into apoptosis. Microbiol Mol Biol. 1997;61:33-46.
-
(1997)
Microbiol Mol Biol
, vol.61
, pp. 33-46
-
-
Anderson, P.1
-
73
-
-
0035866338
-
Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites
-
Rice PL, Goldberg RJ, Ray EC, Driggers LJ, Ahnen DJ. Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites. Cancer Res. 2001;61:1541-1547.
-
(2001)
Cancer Res
, vol.61
, pp. 1541-1547
-
-
Rice, P.L.1
Goldberg, R.J.2
Ray, E.C.3
Driggers, L.J.4
Ahnen, D.J.5
-
74
-
-
0034708456
-
The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons
-
Xue L, Murray JH, Tolkovsky AM. The Ras/phosphatidylinositol 3-kinase and Ras/ERK pathways function as independent survival modules each of which inhibits a distinct apoptotic signaling pathway in sympathetic neurons. J Biol Chem. 2000;275:8817-8824.
-
(2000)
J Biol Chem
, vol.275
, pp. 8817-8824
-
-
Xue, L.1
Murray, J.H.2
Tolkovsky, A.M.3
-
75
-
-
0035866406
-
Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells
-
Stadheim TA, Xiao H, Eastman A. Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells. Cancer Res. 2001;61:1533-1540.
-
(2001)
Cancer Res
, vol.61
, pp. 1533-1540
-
-
Stadheim, T.A.1
Xiao, H.2
Eastman, A.3
-
76
-
-
0033168034
-
2-terminal kinase-dependent p53-independent pathway
-
2-terminal kinase-dependent p53-independent pathway. Cancer Res. 1999;59:3053-3058.
-
(1999)
Cancer Res
, vol.59
, pp. 3053-3058
-
-
Huang, C.1
Ma, W.Y.2
Li, J.3
Dong, Z.4
-
77
-
-
0033583321
-
Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and independent pathways in ovarian cancer cells
-
Wang TH, Popp DM, Wang HS, et al. Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and independent pathways in ovarian cancer cells. J Biol Chem. 1999;274:8208-8216.
-
(1999)
J Biol Chem
, vol.274
, pp. 8208-8216
-
-
Wang, T.H.1
Popp, D.M.2
Wang, H.S.3
-
78
-
-
0035815716
-
Activated JNK phosphorylates the C-terminal domain of MLK2 that is required for MLK2 induced apoptosis
-
Phelan DR, Price G, Liu YF, Dorow DS. Activated JNK phosphorylates the C-terminal domain of MLK2 that is required for MLK2 induced apoptosis. J Biol Chem. 2001;276:10801-10810.
-
(2001)
J Biol Chem
, vol.276
, pp. 10801-10810
-
-
Phelan, D.R.1
Price, G.2
Liu, Y.F.3
Dorow, D.S.4
|