Inhibition of extracellular signal-regulated kinase 1/2 phosphorylation and induction of apoptosis by sulindac metabolites

Cancer Research

Volumn 61, Issue 4, 2001, Pages 1541-1547

  Rice, Pamela L ^a,b   Goldberg, Ryan J ^b   Ray, Evan C ^b   Driggers, Linda J ^b   Ahnen, Dennis J ^a,b  

^a UNIVERSITY OF COLORADO   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; SULINDAC; SULINDAC SULFIDE; SULINDAC SULFONE;

APOPTOSIS; ARTICLE; CELL STRUCTURE; CHEMOPROPHYLAXIS; COLON CANCER; CONTROLLED STUDY; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENCY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

3',5'-CYCLIC-GMP PHOSPHODIESTERASE; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; APOPTOSIS; BUTADIENES; CASPASE 3; CASPASE 7; CASPASES; COLONIC NEOPLASMS; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; MAP KINASE KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; NITRILES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SULINDAC; TUMOR CELLS, CULTURED;

EID: 0035866338     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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