메뉴 건너뛰기




Volumn 71, Issue 5, 2003, Pages 2643-2655

Gene expression profiling of Helicobacter pylori reveals a growth-phase-dependent switch in virulence gene expression

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL PROTEIN; FLAGELLIN; INTERLEUKIN 8; PROTEIN FECA; PROTEIN FRPB; PROTEIN PFR; UNCLASSIFIED DRUG;

EID: 0242417000     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.5.2643-2655.2003     Document Type: Article
Times cited : (123)

References (57)
  • 1
    • 0034076830 scopus 로고    scopus 로고
    • Identification of the urease operon in Helicobacter pylori and its control by mRNA decay in response to pH
    • Akada, J. K., M. Shirai, H. Takeuchi, M. Tsuda, and T. Nakazawa. 2000. Identification of the urease operon in Helicobacter pylori and its control by mRNA decay in response to pH. Mol. Microbiol. 36:1071-1084.
    • (2000) Mol. Microbiol. , vol.36 , pp. 1071-1084
    • Akada, J.K.1    Shirai, M.2    Takeuchi, H.3    Tsuda, M.4    Nakazawa, T.5
  • 2
    • 0034858331 scopus 로고    scopus 로고
    • Characterization of the low-pH responses of Helicobacter pylori using genomic DNA arrays
    • Allan, E., C. L. Clayton, A. McLaren, D. M. Wallace, and B. W. Wren. 2001. Characterization of the low-pH responses of Helicobacter pylori using genomic DNA arrays. Microbiology 147:2285-2292.
    • (2001) Microbiology , vol.147 , pp. 2285-2292
    • Allan, E.1    Clayton, C.L.2    McLaren, A.3    Wallace, D.M.4    Wren, B.W.5
  • 3
    • 0033918170 scopus 로고    scopus 로고
    • Comparative genomics of Helicobacter pylori: Analysis of the outer membrane protein families
    • Alm, R. A., J. Bina, B. M. Andrews, P. Doig, R. E. Hancock, and T. J. Trust. 2000. Comparative genomics of Helicobacter pylori: analysis of the outer membrane protein families. Infect. Immun. 68:4155-4168.
    • (2000) Infect. Immun. , vol.68 , pp. 4155-4168
    • Alm, R.A.1    Bina, J.2    Andrews, B.M.3    Doig, P.4    Hancock, R.E.5    Trust, T.J.6
  • 5
    • 0035117352 scopus 로고    scopus 로고
    • Acid-induced gene expression in Helicobacter pylori: Study in genomic scale by microarray
    • Ang, S., C. Z. Lee, K. Peck, M. Sindici, U. Matrubutham, M. A. Gleeson, and J. T. Wang. 2001. Acid-induced gene expression in Helicobacter pylori: study in genomic scale by microarray. Infect. Immun. 69:1679-1686.
    • (2001) Infect. Immun. , vol.69 , pp. 1679-1686
    • Ang, S.1    Lee, C.Z.2    Peck, K.3    Sindici, M.4    Matrubutham, U.5    Gleeson, M.A.6    Wang, J.T.7
  • 7
    • 0036246084 scopus 로고    scopus 로고
    • Helicobacter pylori-related iron deficiency anemia: A review
    • Barabino, A. 2002. Helicobacter pylori-related iron deficiency anemia: a review. Helicobacter 7:71-75.
    • (2002) Helicobacter , vol.7 , pp. 71-75
    • Barabino, A.1
  • 8
    • 0033973782 scopus 로고    scopus 로고
    • Identification and molecular analysis of superoxide dismutase isoforms in Helicobacter pylori
    • Bereswill, S., O. Neuner, S. Strobel, and M. Kist. 2000. Identification and molecular analysis of superoxide dismutase isoforms in Helicobacter pylori. FEMS Microbiol Lett. 183:241-245.
    • (2000) FEMS Microbiol. Lett. , vol.183 , pp. 241-245
    • Bereswill, S.1    Neuner, O.2    Strobel, S.3    Kist, M.4
  • 9
    • 0031685512 scopus 로고    scopus 로고
    • Structural, functional and mutational analysis of the pfr gene encoding a ferritin from Helicobacter pylori
    • Bereswill, S., U. Waidner, S. Odenbreit, F. Lichte, F. Fassbinder, G. Bode, and M. Kist. 1998. Structural, functional and mutational analysis of the pfr gene encoding a ferritin from Helicobacter pylori. Microbiology 144:2505-2516.
    • (1998) Microbiology , vol.144 , pp. 2505-2516
    • Bereswill, S.1    Waidner, U.2    Odenbreit, S.3    Lichte, F.4    Fassbinder, F.5    Bode, G.6    Kist, M.7
  • 11
    • 0029126262 scopus 로고
    • Occurrence of the regulatory nucleotides ppGpp and pppGpp following induction of the stringent response in staphylococci
    • Cassels, R., B. Oliva, and D. Knowles. 1995. Occurrence of the regulatory nucleotides ppGpp and pppGpp following induction of the stringent response in staphylococci. J. Bacteriol. 177:5161-5165.
    • (1995) J. Bacteriol. , vol.177 , pp. 5161-5165
    • Cassels, R.1    Oliva, B.2    Knowles, D.3
  • 13
    • 0035075387 scopus 로고    scopus 로고
    • Revisiting the stringent response, ppGpp and starvation signaling
    • Chatterji, D., and A. K. Ojha. 2001. Revisiting the stringent response, ppGpp and starvation signaling. Curr. Opin. Microbiol. 4:160-165.
    • (2001) Curr. Opin. Microbiol. , vol.4 , pp. 160-165
    • Chatterji, D.1    Ojha, A.K.2
  • 15
    • 0035724513 scopus 로고    scopus 로고
    • The Fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pylori
    • Delany, I., G. Spohn, R. Rappuoli, and V. Scarlato. 2001. The Fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pylori. Mol. Microbiol. 42:1297-1309.
    • (2001) Mol. Microbiol. , vol.42 , pp. 1297-1309
    • Delany, I.1    Spohn, G.2    Rappuoli, R.3    Scarlato, V.4
  • 17
    • 0035826697 scopus 로고    scopus 로고
    • Host microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell death
    • Detweiler, C. S., D. B. Cunanan, and S. Falkow. 2001. Host microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell death. Proc. Natl. Acad. Sci. USA 98:5850-5855.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5850-5855
    • Detweiler, C.S.1    Cunanan, D.B.2    Falkow, S.3
  • 18
    • 0036182049 scopus 로고    scopus 로고
    • Gastric MALT lymphoma: From aetiology to treatment
    • Du, M. Q., and P. G. Isaccson. 2002. Gastric MALT lymphoma: from aetiology to treatment. Lancet Oncol. 3:97-104.
    • (2002) Lancet Oncol. , vol.3 , pp. 97-104
    • Du, M.Q.1    Isaccson, P.G.2
  • 19
    • 0035873182 scopus 로고    scopus 로고
    • Neutrophil-activating protein (HP-NAP) versus ferritin (Pfr): Comparison of synthesis in Helicobacter pylori
    • Dundon, W. G., A. Polenghi, G. Del Guidice, R. Rappuoli, and C. Montecucco. 2001. Neutrophil-activating protein (HP-NAP) versus ferritin (Pfr): comparison of synthesis in Helicobacter pylori. FEMS Microbiol. Lett. 199: 143-149.
    • (2001) FEMS Microbiol. Lett. , vol.199 , pp. 143-149
    • Dundon, W.G.1    Polenghi, A.2    Del Guidice, G.3    Rappuoli, R.4    Montecucco, C.5
  • 20
    • 0033031437 scopus 로고    scopus 로고
    • DNA arrays for analysis of gene expression
    • Eisen, M. B., and P. O. Brown. 1999. DNA arrays for analysis of gene expression. Methods Enzymol. 303:179-205.
    • (1999) Methods Enzymol. , vol.303 , pp. 179-205
    • Eisen, M.B.1    Brown, P.O.2
  • 22
    • 0028843199 scopus 로고
    • Identification of four new prokaryotic bacterioferritins, from Helicobacter pylori, Anabaena variabilis, Bacillus subtilis and Treponema pallidum, by analysis of gene sequences
    • Evans, D. J., Jr., D. G. Evans, H. C. Lampert, and H. Nakano. 1995. Identification of four new prokaryotic bacterioferritins, from Helicobacter pylori, Anabaena variabilis, Bacillus subtilis and Treponema pallidum, by analysis of gene sequences. Gene 153:123-127.
    • (1995) Gene , vol.153 , pp. 123-127
    • Evans D.J., Jr.1    Evans, D.G.2    Lampert, H.C.3    Nakano, H.4
  • 24
    • 0035725211 scopus 로고    scopus 로고
    • Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: Essential genes for CagA translocation in host cells and induction of interleukin-8
    • Fischer, W., J. Puls, R. Buhrdorf, B. Gebert, S. Odenbreit, and R. Haas. 2001. Systematic mutagenesis of the Helicobacter pylori cag pathogenicity island: essential genes for CagA translocation in host cells and induction of interleukin-8. Mol. Microbiol. 42:1337-1348.
    • (2001) Mol. Microbiol. , vol.42 , pp. 1337-1348
    • Fischer, W.1    Puls, J.2    Buhrdorf, R.3    Gebert, B.4    Odenbreit, S.5    Haas, R.6
  • 25
    • 0033909787 scopus 로고    scopus 로고
    • Transcriptional analysis of major heat shock genes of Helicobacter pylori
    • Homuth, G., S. Domm, D. Kleiner, and W. Schumann. 2000. Transcriptional analysis of major heat shock genes of Helicobacter pylori. J. Bacteriol. 182: 4257-4263.
    • (2000) J. Bacteriol. , vol.182 , pp. 4257-4263
    • Homuth, G.1    Domm, S.2    Kleiner, D.3    Schumann, W.4
  • 26
    • 0035576880 scopus 로고    scopus 로고
    • Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways in Streptomyces coelicolor using DNA microarrays
    • Huang, J., C. J. Lih, K. H. Pan, and S. N. Cohen. 2001. Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways in Streptomyces coelicolor using DNA microarrays. Genes Dev. 15:3183-3192.
    • (2001) Genes Dev. , vol.15 , pp. 3183-3192
    • Huang, J.1    Lih, C.J.2    Pan, K.H.3    Cohen, S.N.4
  • 27
    • 0030886291 scopus 로고    scopus 로고
    • A flagellar sheath protein of Helicobacter pylori is identical to HpaA, a putative N-acetylneuraminyllactose-binding hemagglutinin, but is not an adhesin for AGS cells
    • Jones, A. C., R. P. Logan, S. Foynes, A. Cockayne, B. W. Wren, and C. W. Penn. 1997. A flagellar sheath protein of Helicobacter pylori is identical to HpaA, a putative N-acetylneuraminyllactose-binding hemagglutinin, but is not an adhesin for AGS cells. J. Bacteriol. 179:5643-5647.
    • (1997) J. Bacteriol. , vol.179 , pp. 5643-5647
    • Jones, A.C.1    Logan, R.P.2    Foynes, S.3    Cockayne, A.4    Wren, B.W.5    Penn, C.W.6
  • 28
    • 0033915316 scopus 로고    scopus 로고
    • Switching of flagellar motility in Helicobacter pylori by reversible length variation of a short homopolymeric sequence repeat in fliP, a gene encoding a basal body protein
    • Josenhans, C., K. A. Eaton, T. Thevenot, and S. Suerbaum. 2000. Switching of flagellar motility in Helicobacter pylori by reversible length variation of a short homopolymeric sequence repeat in fliP, a gene encoding a basal body protein. Infect. Immun. 68:4598-4603.
    • (2000) Infect. Immun. , vol.68 , pp. 4598-4603
    • Josenhans, C.1    Eaton, K.A.2    Thevenot, T.3    Suerbaum, S.4
  • 29
    • 0029019564 scopus 로고
    • Comparative ultrastructural and functional studies of Helicobacter pylori and Helicobacter mustelae flagellin mutants: Both flagellin subunits, FlaA and FlaB, are necessary for full motility in Helicobacter species
    • Josenhans, C., A. Labigne, and S. Suerbaum. 1995. Comparative ultrastructural and functional studies of Helicobacter pylori and Helicobacter mustelae flagellin mutants: both flagellin subunits, FlaA and FlaB, are necessary for full motility in Helicobacter species. J. Bacteriol. 177:3010-3020.
    • (1995) J. Bacteriol. , vol.177 , pp. 3010-3020
    • Josenhans, C.1    Labigne, A.2    Suerbaum, S.3
  • 30
    • 0036169909 scopus 로고    scopus 로고
    • Functional characterization of the antagonistic flagellar late regulators FliA and FlgM of Helicobacter pylori and their effects on the H. pylori transcriptome
    • Josenhans, C., E. Niehus, S. Amersbach, A. Horster, C. Betz, B. Drescher, K. T. Hughes, and S. Suerbaum. 2002. Functional characterization of the antagonistic flagellar late regulators FliA and FlgM of Helicobacter pylori and their effects on the H. pylori transcriptome. Mol. Microbiol. 43:307-322.
    • (2002) Mol. Microbiol. , vol.43 , pp. 307-322
    • Josenhans, C.1    Niehus, E.2    Amersbach, S.3    Horster, A.4    Betz, C.5    Drescher, B.6    Hughes, K.T.7    Suerbaum, S.8
  • 31
    • 0034972994 scopus 로고    scopus 로고
    • Differential gene expression from two transcriptional units in the cag pathogenicity island of Helicobacter pylori
    • Joyce, E. A., J. V. Gilbert, K. A. Eaton, A. Plaut, and A. Wright. 2001. Differential gene expression from two transcriptional units in the cag pathogenicity island of Helicobacter pylori. Infect. Immun. 69:4202-4209.
    • (2001) Infect. Immun. , vol.69 , pp. 4202-4209
    • Joyce, E.A.1    Gilbert, J.V.2    Eaton, K.A.3    Plaut, A.4    Wright, A.5
  • 33
    • 0034671792 scopus 로고    scopus 로고
    • Global analysis of the genetic network controlling a bacterial cell cycle
    • Laub, M. T., H. H. McAdams, T. Feldblyum, C. M. Fraser, and L. Shapiro. 2000. Global analysis of the genetic network controlling a bacterial cell cycle. Science 290:2144-2148.
    • (2000) Science , vol.290 , pp. 2144-2148
    • Laub, M.T.1    McAdams, H.H.2    Feldblyum, T.3    Fraser, C.M.4    Shapiro, L.5
  • 35
    • 0033032482 scopus 로고    scopus 로고
    • Growth phase-regulated induction of Salmonella-induced macrophage apoptosis correlates with transient expression of SPI-1 genes
    • Lundberg, U., U. Vinatzer, D. Berdnik, A. von Gabain, and M. Baccarini. 1999. Growth phase-regulated induction of Salmonella-induced macrophage apoptosis correlates with transient expression of SPI-1 genes. J. Bacteriol. 181:3433-3437.
    • (1999) J. Bacteriol. , vol.181 , pp. 3433-3437
    • Lundberg, U.1    Vinatzer, U.2    Berdnik, D.3    Von Gabain, A.4    Baccarini, M.5
  • 38
    • 0021259505 scopus 로고
    • Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration
    • Marshall, B. J., and J. R. Warren. 1984. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet i:1311-1315.
    • (1984) Lancet , vol.1 , pp. 1311-1315
    • Marshall, B.J.1    Warren, J.R.2
  • 40
    • 0032704187 scopus 로고    scopus 로고
    • The cadA gene of Vibrio cholerae is induced during infection and plays a role in acid tolerance
    • Merrell, D. S., and A. Camilli. 1999. The cadA gene of Vibrio cholerae is induced during infection and plays a role in acid tolerance. Mol. Microbiol. 34:836-849.
    • (1999) Mol. Microbiol. , vol.34 , pp. 836-849
    • Merrell, D.S.1    Camilli, A.2
  • 41
    • 0035010085 scopus 로고    scopus 로고
    • Pasteurella multocida gene expression in response to iron limitation
    • Paustian, M. L., B. J. May, and V. Kapur. 2001. Pasteurella multocida gene expression in response to iron limitation. Infect. Immun. 69:4109-4115.
    • (2001) Infect. Immun. , vol.69 , pp. 4109-4115
    • Paustian, M.L.1    May, B.J.2    Kapur, V.3
  • 42
    • 0036370334 scopus 로고    scopus 로고
    • Helicobacter pylori and gastrointestinal tract adenocarcinomas
    • Peek, R. M., Jr., and M. J. Blaser. 2002. Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat. Rev. Cancer 2:28-37.
    • (2002) Nat. Rev. Cancer. , vol.2 , pp. 28-37
    • Peek R.M., Jr.1    Blaser, M.J.2
  • 43
    • 0034524769 scopus 로고    scopus 로고
    • Role of iron in Helicobacter pylori: Its influence in outer membrane protein expression and in pathogenicity
    • Perez-Perez, G. I., and D. A. Israel. 2000. Role of iron in Helicobacter pylori: its influence in outer membrane protein expression and in pathogenicity. Eur. J. Gastroenterol. Hepatol. 12:1263-1265.
    • (2000) Eur. J. Gastroenterol. Hepatol. , vol.12 , pp. 1263-1265
    • Perez-Perez, G.I.1    Israel, D.A.2
  • 47
    • 0036239133 scopus 로고    scopus 로고
    • TraG-like proteins of DNA transfer systems and of the Helicobacter pylori type IV secretion system: Inner membrane gate for exported substrates?
    • Schroder, G., S. Krause, E. L. Zechner, B. Traxler, H. J. Yeo, R. Lurz, G. Waksman, and E. Lanka. 2002. TraG-like proteins of DNA transfer systems and of the Helicobacter pylori type IV secretion system: inner membrane gate for exported substrates? J. Bacteriol. 184:2767-2779.
    • (2002) J. Bacteriol. , vol.184 , pp. 2767-2779
    • Schroder, G.1    Krause, S.2    Zechner, E.L.3    Traxler, B.4    Yeo, H.J.5    Lurz, R.6    Waksman, G.7    Lanka, E.8
  • 48
    • 0032921887 scopus 로고    scopus 로고
    • Helicobacter pylori: A eubacterium lacking the stringent response
    • Scoarughi, G. L., C. Cimmino, and P. Donini. 1999. Helicobacter pylori: a eubacterium lacking the stringent response. J. Bacteriol. 181:552-555.
    • (1999) J. Bacteriol. , vol.181 , pp. 552-555
    • Scoarughi, G.L.1    Cimmino, C.2    Donini, P.3
  • 49
    • 0030034805 scopus 로고    scopus 로고
    • Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylation of host cell proteins
    • Segal, E. D., S. Falkow, and L. S. Tompkins. 1996. Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylation of host cell proteins. Proc. Natl. Acad. Sci. USA 93:1259-1264.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 1259-1264
    • Segal, E.D.1    Falkow, S.2    Tompkins, L.S.3
  • 52
    • 0032730207 scopus 로고    scopus 로고
    • The autoregulatory HspR repressor protein governs chaperone gene transcription in Helicobacter pylori
    • Spohn, G., and V. Scarlato. 1999. The autoregulatory HspR repressor protein governs chaperone gene transcription in Helicobacter pylori. Mol. Microbiol. 34:663-674.
    • (1999) Mol. Microbiol. , vol.34 , pp. 663-674
    • Spohn, G.1    Scarlato, V.2
  • 53
    • 0032589796 scopus 로고    scopus 로고
    • Motility of Helicobacter pylori is coordinately regulated by the transcriptional activator FlgR, an NtrC homolog
    • Spohn, G., and V. Scarlato. 1999. Motility of Helicobacter pylori is coordinately regulated by the transcriptional activator FlgR, an NtrC homolog. J. Bacteriol. 181:593-599.
    • (1999) J. Bacteriol. , vol.181 , pp. 593-599
    • Spohn, G.1    Scarlato, V.2
  • 55
    • 0035942271 scopus 로고    scopus 로고
    • Significance analysis of microarrays applied to the ionizing radiation response
    • Tusher, V. G., R. Tibshirani, and G. Chu. 2001. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98:5116-5121.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 5116-5121
    • Tusher, V.G.1    Tibshirani, R.2    Chu, G.3
  • 56
    • 0032849071 scopus 로고    scopus 로고
    • The relationship between Helicobacter pylori motility, morphology and phase of growth: Implications for gastric colonization and pathology
    • Worku, M. L., R. L. Sidebotham, M. M. Walker, T. Keshavarz, and Q. N. Karim. 1999. The relationship between Helicobacter pylori motility, morphology and phase of growth: implications for gastric colonization and pathology. Microbiology 145:2803-2811.
    • (1999) Microbiology , vol.145 , pp. 2803-2811
    • Worku, M.L.1    Sidebotham, R.L.2    Walker, M.M.3    Keshavarz, T.4    Karim, Q.N.5
  • 57
    • 0029128940 scopus 로고
    • Iron-repressible outer membrane proteins of Helicobacter pylori involved in heme uptake
    • Worst, D. J., B. R. Otto, and J. de Graaff. 1995. Iron-repressible outer membrane proteins of Helicobacter pylori involved in heme uptake. Infect. Immun. 63:4161-4165.
    • (1995) Infect. Immun. , vol.63 , pp. 4161-4165
    • Worst, D.J.1    Otto, B.R.2    De Graaff, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.