-
1
-
-
0001100915
-
Untersuchungen über das Choleragift
-
Pfeiffer R. Untersuchungen über das Choleragift. Z Hygiene 1892; 11: 393-412.
-
(1892)
Z. Hygiene
, vol.11
, pp. 393-412
-
-
Pfeiffer, R.1
-
2
-
-
0037317763
-
Timeline: Innate immune sensing and its roots: The story of endotoxin
-
Beutler B, Rietschel ET. Timeline: Innate immune sensing and its roots: the story of endotoxin. Nat Rev Immunol 2003; 3: 169-76.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 169-176
-
-
Beutler, B.1
Rietschel, E.T.2
-
3
-
-
0018841829
-
Genetic control of susceptibility to Salmonella typhimurium in mice: Role of the LPS gene
-
O'Brien AD, Rosenstreich DL, Scher I, Campbell GH, MacDermott RP, Formal SB. Genetic control of susceptibility to Salmonella typhimurium in mice: role of the LPS gene. J Immunol 1980; 124:20-4.
-
(1980)
J. Immunol.
, vol.124
, pp. 20-24
-
-
O'Brien, A.D.1
Rosenstreich, D.L.2
Scher, I.3
Campbell, G.H.4
MacDermott, R.P.5
Formal, S.B.6
-
5
-
-
0021703558
-
Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice
-
Hagberg L, Hull R, Hull S, McGhee JR, Michalek SM, Svanborg Eden C. Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN mice. Infect Immun 1984; 46: 839-44.
-
(1984)
Infect. Immun.
, vol.46
, pp. 839-844
-
-
Hagberg, L.1
Hull, R.2
Hull, S.3
McGhee, J.R.4
Michalek, S.M.5
Svanborg Eden, C.6
-
7
-
-
0018858071
-
The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxin
-
Michalek SM, Moore RN, McGhee JR, Rosenstreich DL, Mergenhagen SE. The primary role of lymphoreticular cells in the mediation of host responses to bacterial endotoxin. J Infect Dis 1980; 141: 55-63.
-
(1980)
J. Infect. Dis.
, vol.141
, pp. 55-63
-
-
Michalek, S.M.1
Moore, R.N.2
McGhee, J.R.3
Rosenstreich, D.L.4
Mergenhagen, S.E.5
-
8
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
Wright SD, Ramos RA, Tobias PS, Ulevitch RJ, Mathison JC. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 1990; 249: 1431-3.
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
9
-
-
0029919991
-
Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice
-
Haziot A, Ferrero E, Kontgen F, Hijiya N, Yamamoto S, Silver J, et al. Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity 1996; 4: 407-14.
-
(1996)
Immunity
, vol.4
, pp. 407-414
-
-
Haziot, A.1
Ferrero, E.2
Kontgen, F.3
Hijiya, N.4
Yamamoto, S.5
Silver, J.6
-
10
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, Liu M-Y, Van Huffel C, Du X, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282: 2085-8.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.-Y.4
Van Huffel, C.5
Du, X.6
-
11
-
-
0032170215
-
Genetic and physical mapping of the Lps locus - Identification of the toll-4 receptor as a candidate gene in the critical region
-
Poltorak A, Smirnova I, He XL, Liu MY, Van Huffel C, McNally O, et al. Genetic and physical mapping of the Lps locus - identification of the toll-4 receptor as a candidate gene in the critical region. Blood Cells Mol Dis 1998; 24: 340-55.
-
(1998)
Blood Cells Mol. Dis.
, vol.24
, pp. 340-355
-
-
Poltorak, A.1
Smirnova, I.2
He, X.L.3
Liu, M.Y.4
Van Huffel, C.5
McNally, O.6
-
12
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM, Hoffmann JA. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996; 86: 973-83.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B.1
Nicolas, E.2
Michaut, L.3
Reichhart, J.M.4
Hoffmann, J.A.5
-
13
-
-
0034456693
-
Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
-
Du X, Poltorak A, Wei Y, Beutler B. Three novel mammalian toll-like receptors: gene structure, expression, and evolution. Eur Cytokine Netw 2000; 11: 362-71.
-
(2000)
Eur. Cytokine Netw.
, vol.11
, pp. 362-371
-
-
Du, X.1
Poltorak, A.2
Wei, Y.3
Beutler, B.4
-
14
-
-
0034457684
-
Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9
-
Chuang TH, Ulevitch RJ. Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9. Eur Cytokine Netw 2000; 11: 372-8.
-
(2000)
Eur. Cytokine Netw.
, vol.11
, pp. 372-378
-
-
Chuang, T.H.1
Ulevitch, R.J.2
-
16
-
-
0034002247
-
Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide
-
Lien E, Means TK, Heine H, Yoshimura A, Kusumoto S, Fukase K, et al. Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide. J Clin Invest 2000; 105: 497-504.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 497-504
-
-
Lien, E.1
Means, T.K.2
Heine, H.3
Yoshimura, A.4
Kusumoto, S.5
Fukase, K.6
-
17
-
-
0033532629
-
MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
-
Shimazu R, Akashi S, Ogata H, Nagai Y, Fukudome K, Miyake K, Kimoto M. MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J Exp Med 1999; 189: 1777-82.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1777-1782
-
-
Shimazu, R.1
Akashi, S.2
Ogata, H.3
Nagai, Y.4
Fukudome, K.5
Miyake, K.6
Kimoto, M.7
-
18
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
Nagai Y, Akashi S, Nagafuku M, Ogata M, Iwakura Y, Akira S, et al. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat Immunol 2002; 3: 667-72.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
Akira, S.6
-
19
-
-
0035877718
-
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex: Transfer from CD14 to TLR4 and MD-2
-
da Silva CJ, Soldau K, Christen U, Tobias PS, Ulevitch RJ. Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex: transfer from CD14 to TLR4 and MD-2. J Biol Chem 2001; 276: 21129-35.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21129-21135
-
-
da Silva, C.J.1
Soldau, K.2
Christen, U.3
Tobias, P.S.4
Ulevitch, R.J.5
-
20
-
-
0035555301
-
TIRAP: An adapter molecule in the Toll signaling pathway
-
Horng T, Barton GM, Medzhitov R. TIRAP: an adapter molecule in the Toll signaling pathway. Nat Immunol 2001; 2: 835-41.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 835-841
-
-
Horng, T.1
Barton, G.M.2
Medzhitov, R.3
-
21
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, et al. Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 2001; 413: 78-83.
-
(2001)
Nature
, vol.413
, pp. 78-83
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
-
22
-
-
0037153130
-
The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors
-
Horng T, Barton GM, Flavell RA, Medzhitov R. The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. Nature 2002; 420: 329-33.
-
(2002)
Nature
, vol.420
, pp. 329-333
-
-
Horng, T.1
Barton, G.M.2
Flavell, R.A.3
Medzhitov, R.4
-
23
-
-
0037153191
-
Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4
-
Yamamoto M, Sato S, Hemmi H, Sanjo H, Uematsu S, Kaisho T, et al. Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4. Nature 2002; 420: 324-9.
-
(2002)
Nature
, vol.420
, pp. 324-329
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Sanjo, H.4
Uematsu, S.5
Kaisho, T.6
-
24
-
-
0038448236
-
Lps2: A new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening
-
Hoebe K, Du X, Goode J, Mann N, Beutler B. Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening. J Endotoxin Res 2003; 9: 250-5.
-
(2003)
J. Endotoxin. Res.
, vol.9
, pp. 250-255
-
-
Hoebe, K.1
Du, X.2
Goode, J.3
Mann, N.4
Beutler, B.5
-
25
-
-
0037114185
-
Cutting edge: A novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling
-
Yamamoto M, Sato S, Mori K, Hoshino K, Takeuchi O, Takeda K, Akira S. Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling. J Immunol 2002; 169: 6668-72.
-
(2002)
J. Immunol.
, vol.169
, pp. 6668-6672
-
-
Yamamoto, M.1
Sato, S.2
Mori, K.3
Hoshino, K.4
Takeuchi, O.5
Takeda, K.6
Akira, S.7
-
26
-
-
0037320451
-
TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction
-
Oshiumi H, Matsumoto M, Funami K, Akazawa T, Seya T. TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction. Nat Immunol 2003; 4: 161-71.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 161-171
-
-
Oshiumi, H.1
Matsumoto, M.2
Funami, K.3
Akazawa, T.4
Seya, T.5
-
27
-
-
0042679529
-
Identification of Lps2 as a key transducer of MyD88-independent TIR signaling
-
Hoebe K, Du X, Georgel P, Janssen E, Tabeta K, Kim SO, Goode J, Lin P, Mann N, Mudd S, Crozat K, Sovath S, Han J, Beutler B. Identification of Lps2 as a key transducer of MyD88-independent TIR signaling. Nature 2003; 424: 743-8.
-
(2003)
Nature
, vol.424
, pp. 743-748
-
-
Hoebe, K.1
Du, X.2
Georgel, P.3
Janssen, E.4
Tabeta, K.5
Kim, S.O.6
Goode, J.7
Lin, P.8
Mann, N.9
Mudd, S.10
Crozat, K.11
Sovath, S.12
Han, J.13
Beutler, B.14
-
28
-
-
0017394407
-
Inheritance of lipopolysaccharide-enhanced nonspecific resistance to infection and of susceptibility to endotoxic shock in lipopolysaccharide low-responder mice
-
Parant M, Parant F, Chedid L. Inheritance of lipopolysaccharide-enhanced nonspecific resistance to infection and of susceptibility to endotoxic shock in lipopolysaccharide low-responder mice. Infect Immun 1977; 16: 432-8.
-
(1977)
Infect. Immun.
, vol.16
, pp. 432-438
-
-
Parant, M.1
Parant, F.2
Chedid, L.3
-
29
-
-
0017236507
-
Failure of endotoxin to increase nonspecific resistance to infection of lipopolysaccharide low-responder mice
-
Chedid L, Parant M, Damais C, Parant F, Juy D, Galelli A. Failure of endotoxin to increase nonspecific resistance to infection of lipopolysaccharide low-responder mice. Infect Immun 1976; 13: 722-7.
-
(1976)
Infect. Immun.
, vol.13
, pp. 722-727
-
-
Chedid, L.1
Parant, M.2
Damais, C.3
Parant, F.4
Juy, D.5
Galelli, A.6
-
30
-
-
0022544882
-
Immunobiological activities of nontoxic lipid A: Enhancement of nonspecific resistance in combination with trehalose dimycolate against viral infection and adjuvant effects
-
Masihi KN, Lange W, Brehmer W, Ribi E. Immunobiological activities of nontoxic lipid A: enhancement of nonspecific resistance in combination with trehalose dimycolate against viral infection and adjuvant effects. Int J Immunopharmacol 1986; 8: 339-45.
-
(1986)
Int. J. Immunopharmacol.
, vol.8
, pp. 339-345
-
-
Masihi, K.N.1
Lange, W.2
Brehmer, W.3
Ribi, E.4
-
31
-
-
0022992861
-
Enhancement of chemiluminescence and phagocytic activities by nontoxic and toxic forms of lipid A
-
Masihi KN, Lange W, Johnson AG, Ribi E. Enhancement of chemiluminescence and phagocytic activities by nontoxic and toxic forms of lipid A. J Biol Response Mod 1986; 5: 462-9.
-
(1986)
J. Biol. Response Mod.
, vol.5
, pp. 462-469
-
-
Masihi, K.N.1
Lange, W.2
Johnson, A.G.3
Ribi, E.4
-
32
-
-
34250431923
-
Endotoxin-induced protection against experimental Junin virus infection
-
Budzko DB, Kierszenbaum F. Endotoxin-induced protection against experimental Junin virus infection. Arch Gesamte Virusforsch 1973; 41: 203-10.
-
(1973)
Arch. Gesamte Virusforsch.
, vol.41
, pp. 203-210
-
-
Budzko, D.B.1
Kierszenbaum, F.2
-
33
-
-
0015622554
-
Interferon tolerance and antiviral protection in mice given single or multiple injections of endotoxin or poly I: C
-
Giron DJ, Schmidt JP, Pindak FF, Connell JE. Interferon tolerance and antiviral protection in mice given single or multiple injections of endotoxin or poly I: C. Acta Virol 1973; 17: 209-14.
-
(1973)
Acta Virol.
, vol.17
, pp. 209-214
-
-
Giron, D.J.1
Schmidt, J.P.2
Pindak, F.F.3
Connell, J.E.4
-
34
-
-
0022371461
-
Identity of tumour necrosis factor and the macrophage-secreted factor cachectin
-
Beutler B, Greenwald D, Hulmes JD, Chang M, Pan Y-CE, Mathison J, et al. Identity of tumour necrosis factor and the macrophage-secreted factor cachectin. Nature 1985; 316: 552-4.
-
(1985)
Nature
, vol.316
, pp. 552-554
-
-
Beutler, B.1
Greenwald, D.2
Hulmes, J.D.3
Chang, M.4
Pan, Y.-C.E.5
Mathison, J.6
-
35
-
-
0022411888
-
Passive immunization against cachectin/tumor necrosis factor (TNF) protects mice from the lethal effect of endotoxin
-
Beutler B, Milsark IW, Cerami A. Passive immunization against cachectin/tumor necrosis factor (TNF) protects mice from the lethal effect of endotoxin. Science 1985; 229: 869-71.
-
(1985)
Science
, vol.229
, pp. 869-871
-
-
Beutler, B.1
Milsark, I.W.2
Cerami, A.3
-
36
-
-
0038476601
-
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock
-
Karaghiosoff M, Steinborn R, Kovarik P, Kriegshauser G, Baccarini M, Donabauer B, et al. Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock. Nat Immunol 2003; 4: 471-7.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 471-477
-
-
Karaghiosoff, M.1
Steinborn, R.2
Kovarik, P.3
Kriegshauser, G.4
Baccarini, M.5
Donabauer, B.6
|