Butyrate inhibits pancreatic cancer invasion

Journal of Gastrointestinal Surgery

Volumn 7, Issue 7, 2003, Pages 864-870

  Farrow, Buckminster ^a   Rychahou, Piotr ^a   O'Connor, Kathleen L ^a   Evers, B Mark ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Integrins; Invasion; Pancreatic cancer; Sodium butyrate

Indexed keywords

BUTYRIC ACID; INTEGRIN; MATRIGEL;

ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CANCER INVASION; CELL DIFFERENTIATION; CELL TRANSFORMATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIGESTIVE SYSTEM CANCER; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; METASTASIS; PANCREAS CARCINOMA; PROGNOSIS; PROTEIN EXPRESSION; REDUCTION; RIBONUCLEASE PROTECTION ASSAY; WESTERN BLOTTING;

EID: 0242302537     PISSN: 1091255X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1091-255X(03)00142-2     Document Type: Article

References (32)

1. Jemal A., Murray T., Samuels A., Ghafoor A., Ward E., Thun M.J. Cancer statistics, 2003. CA Cancer J Clin. 53:2003;5-26.
2. Lillemoe K.D., Yeo C.J., Cameron J.L. Pancreatic cancer: State-of-the-art care. CA Cancer J Clin. 50:2000;241-268.
3. Yeo C.J., Abrams R.A., Grochow L.B., Sohn T.A., Ord S.E., Hruban R.H., Zahurak M.L., Dooley W.C., Coleman J., Sauter P.K., Pitt H.A., Lillemoe K.D., Cameron J.L. Pancreaticoduodenectomy for pancreatic adenocarcinoma: Postoperative adjuvant chemoradiation improves survival. A prospective, single-institution experience. Ann Surg. 225:1997;621-636.
4. Ellenrieder V., Adler G., Gress T.M. Invasion and metastasis in pancreatic cancer. Ann Oncol. 10:(Suppl 4):1999;46-50.
5. Mercurio A.M., Bachelder R.E., Rabinovitz I., O'Connor K.L., Tani T., Shaw L.M. The metastatic odyssey: The integrin connection. Surg Oncol Clin North Am. 10:2001;313-328. viii-ix.
6. Haas T.A., Plow E.F. Integrin-ligand interactions: A year in review. Curr Opin Cell Biol. 6:1994;656-662.
7. Martin K.H., Slack J.K., Boerner S.A., Martin C.C., Parsons J.T. Integrin connections map: To infinity and beyond. Science. 296:2002;1652-1653.
8. Vogelmann R., Kreuser E.D., Adler G., Lutz M.P. Integrin alpha6beta1 role in metastatic behavior of human pancreatic carcinoma cells. Int J Cancer. 80:1999;791-795.
9. Hosotani R., Kawaguchi M., Masui T., Koshiba T., Ida J., Fujimoto K., Wada M., Doi R., Imamura M. Expression of integrin alphaVbeta3 in pancreatic carcinoma: Relation to MMP-2 activation and lymph node metastasis. Pancreas. 25:2002;e30-e35.
10. Sawai H., Takeyama H., Yamamoto M., Furuta A., Funahashi H., Okada Y., Sato M., Tanaka M., Manabe T. Enhancement of integrins by interleukin-1alpha, and their relationship with metastatic and invasive behavior of human pancreatic ductal adenocarcinoma cells. J Surg Oncol. 82:2003;51-56.
11. Litvak D.A., Hwang K.O., Evers B.M., Townsend C.M. Jr. Induction of apoptosis in human gastric cancer by sodium butyrate. Anticancer Res. 20:2000;779-784.
12. Litvak D.A., Evers B.M., Hwang K.O., Hellmich M.R., Ko T.C., Townsend C.M. Jr. Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21Waf1/Cip1 and p27Kip1. Surgery. 124:1998;161-170.
13. Zhang J.S., Wang L., Huang H., Nelson M., Smith D.I. Keratin 23 (K23), a novel acidic keratin, is highly induced by histone deacetylase inhibitors during differentiation of pancreatic cancer cells. Genes Chromosomes Cancer. 30:2001;123-135.
14. Saito A., Yamashita T., Mariko Y., Nosaka Y., Tsuchiya K., Ando T., Suzuki T., Tsuruo T., Nakanishi O. A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors. Proc Natl Acad Sci U S A. 96:1999;4592-4597.
15. Wang Q., Wang X., Hernandez A., Hellmich M.R., Gatalica Z., Evers B.M. Regulation of TRAIL expression by the phosphatidylinositol 3-kinase/Akt/GSK-3 pathway in human colon cancer cells. J Biol Chem. 277:2002;36602-36610.
16. Bruns C.J., Harbison M.T., Kuniyasu H., Eue I., Fidler I.J. In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice. Neoplasia. 1:1999;50-62.
17. Takamori H., Hiraoka T., Yamamoto T. Expression of tumor-associated carbohydrate antigens correlates with hepatic metastasis of pancreatic cancer: Clinical and experimental studies. Hepatogastroenterology. 43:1996;748-755.
18. Vincan E., Leet C.S., Reyes N.I., Dilley R.J., Thomas R.J., Phillips W.A. Sodium butyrate-induced differentiation of human LIM2537 colon cancer cells decreases GSK-3beta activity and increases levels of both membrane-bound and Apc/axin/GSK-3beta complex-associated pools of beta-catenin. Oncol Res. 12:2000;193-201.
19. O'Connor K.L., Shaw L.M., Mercurio A.M. Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells. J Cell Biol. 143:1998;1749-1760.
20. Gaetano C., Melchiori A., Albini A., Benelli R., Falcioni R., Modesti A., Modica A., Scarpa S., Sacchi A. Retinoic acid negatively regulates beta 4 integrin expression and suppresses the malignant phenotype in a Lewis lung carcinoma cell line. Clin Exp Metastasis. 12:1994;63-72.
21. Shaw L.M., Rabinovitz I., Wang H.H., Toker A., Mercurio A.M. Activation of phosphoinositide 3-OH kinase by the alpha6beta4 integrin promotes carcinoma invasion. Cell. 91:1997;949-960.
22. Cheng J.Q., Ruggeri B., Klein W.M., Sonoda G., Altomare D.A., Watson D.K., Testa J.R. Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc Natl Acad Sci U S A. 93:1996;3636-3641.
23. Tanno S., Mitsuuchi Y., Altomare D.A., Xiao G.H., Testa J.R. AKT activation upregulates insulin-like growth factor I receptor expression and promotes invasiveness of human pancreatic cancer cells. Cancer Res. 61:2001;589-593.
24. Bergman E.N. Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. Physiol Rev. 70:1990;567-590.
25. Candido E.P., Reeves R., Davie J.R. Sodium butyrate inhibits histone deacetylation in cultured cells. Cell. 14:1978;105-113.
26. Wang Q., Li N., Wang X., Kim M.M., Evers B.M. Augmentation of sodium butyrate-induced apoptosis by phosphatidylinositol 3′-kinase inhibition in the KM20 human colon cancer cell line. Clin Cancer Res. 8:2002;1940-1947.
27. Ellerhorst J., Nguyen T., Cooper D.N., Estrov Y., Lotan D., Lotan R. Induction of differentiation and apoptosis in the prostate cancer cell line LNCaP by sodium butyrate and galectin-1. Int J Oncol. 14:1999;225-232.
28. Egawa N., Maillet B., VanDamme B., De Greve J., Kloppel G. Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: A morphological and molecular analysis of four cell lines. Virchows Arch. 429:1996;59-68.
29. Wang X.M., Li J., Evers B.M. Inhibition of proliferation, invasion and adhesion of liver cancer cells by 5-azacytidine and butyrate. Anticancer Res. 19:1999;2901-2906.
30. Dong-Le Bourhis X., Lambrecht V., Boilly B. Transforming growth factor beta 1 and sodium butyrate differentially modulate urokinase plasminogen activator and plasminogen activator inhibitor-1 in human breast normal and cancer cells. Br J Cancer. 77:1998;396-403.
31. Steinert M., Wobus M., Boltze C., Schutz A., Wahlbuhl M., Hamann J., Aust G. Expression and regulation of CD97 in colorectal carcinoma cell lines and tumor tissues. Am J Pathol. 161:2002;1657-1667.
32. Berlin C., Berg E.L., Briskin M.J., Andrew D.P., Kilshaw P.J., Holzmann B., Weissman I.L., Hamann A., Butcher E.C. Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular address in MAdCAM-1. Cell. 74:1993;185-195.