Induction of apoptosis in human gastric cancer by sodium butyrate

Anticancer Research

Volumn 20, Issue 2 A, 2000, Pages 779-784

  Litvak, David A ^a   Hwang, Kevin O ^a   Evers, B Mark ^a   Townsend Jr , Courtney M ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Apoptosis; Cell cycle; Gastric cancer; Sodium butyrate

Indexed keywords

BUTYRIC ACID; PROTEIN BAK; PROTEIN BAX; PROTEIN P21; PROTEIN P27; PROTEIN P53;

APOPTOSIS; ARTICLE; CELL COUNT; CELL PROLIFERATION; CELL VIABILITY; GROWTH INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; STOMACH CANCER;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BUTYRATES; CELL CYCLE PROTEINS; CELL DEATH; CELL DIVISION; CELL SURVIVAL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYCLINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-2; GENES, P53; HUMANS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEINS;

EID: 0034014130     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. th Ed. Philadelphia, Lippincott-Raven, 1997, pp 1021-1054.
2. Breaux JR, Bringaze W, Chappuis C, Cohn I Jr: Adenocarcinoma of the stomach: a review of 35 years and 1710 cases. World J Surg 14: 580-586, 1990.
3. Velazquez OC, Jabbar A, Dematteo RP, Rombeau JL: Butyrate inhibits seeding and growth of colorectal metastases to the liver in mice. Surgery 120: 440-448, 1996.
4. Velazquez OC, Lederer HM, Rombeau JLL: Butyrate and the colonocyte. Implications for neoplasia. Dig Dis Sci 41: 727-739, 1996.
5. Toscani A, Soprano DR, Soprano KJ: Molecular analysis of sodium butyrate-induced growth arrest. Oncogene Res 3: 223-238, 1988.
6. Kim YS, Tsao D, Siddiqui B, Whitehead JS, Arnstein P, Bennett J, Hicks J: Effects of sodium butyrate and dimethylsulfoxide on biochemical properties of human colon cancer cells. Cancer 45: 1185-1192, 1980.
7. Whitehead RH, Young GP, Bhathal S: Effects of short chain fatty acids on a new human colon carcinoma cell line (LIM1215). Gut 27: 1457-1463, 1986.
8. Awad AB, Horvath PJ, Andersen MS: Influence of butyrate on lipid metabolism, survival, and differentiation of colon cancer cells. Nutr Cancer 16: 125-133, 1991.
9. Barnard JA, Warwick G: Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. Cell Growth Differ 4: 495-501, 1993.
10. Wang XM, Wang X, Li J, Evers BM: Effects of 5-azacytidine and butyrate on differentiation and apoptosis of hepatic cancer cell lines. Ann Surg 227: 922-931, 1998.
11. Hague A, Manning AM, Hanlon KA, Huschtscha LI, Hart D, Paraskeva C: Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. Int J Cancer 55: 498-505, 1993.
12. Heerdt BG, Houston MA, Augenlicht LH: Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res 54: 3288-3293, 1994.
13. Litvak DA, Evers BM, Hwang KO, Hellmich MR, Ko TC, Townsend CM Jr: Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21wafl/cipl and p27kipl. Surgery 124: 161-170, 1998.
14. Planchon P, Magnien V, Beaupain R, Mainguene C, Ronco G, Villa P, Brouty-Boye D: Differential effects of butyrate derivatives on human breast cancer cells grown as organotypic nodules in vitro and as xenografts in vivo. In Vivo 6: 605-610, 1992.
15. Cordel S, Heymann MF, Boisteau O, Oliver L, Le Pendu J, Gregoire M, Meflah K: 5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats. J Cancer 3: 924-928, 1997.
16. Kasukabe T, Rephaeli A, Honma Y: An anti-cancer derivative of butyric acid (pivalyloxmethyl buterate) and daunorubicin cooperatively prolong survival of mice inoculated with monocytic leukaemia cells. Br J Cancer 5: 850-854, 1997.
17. Shack S, Miller A, Liu L, Prasanna P, Thibault A, Samid D: Vulnerability of multidrug-resistant tumor cells to the aromatic fatty acids phenylacetate and phenylbutyrate. Clin Cancer Res 2: 865-872, 1996.
18. Ji QS, Chen HY: Effect of sodium butyrate on chromosome number and DNA content of human gastric adenocarcinoma cell line. Shih Yen Sheng Wu Hsueh Pao: J Exp Biol 4: 45-50, 1991.
19. Harper JW, Elledge SJ, Keyomarsi K, Dynlacht B, Tsai LH, Zhang PP, Dobrowolski S, et al: Inhibition of cyclin-dependent kinases by p21. Mol Cell Biol 6: 387-400, 1995.
20. Sherr CJ, Roberts JM: Inhibitors of mammalian Gl cyclin-dependent kinases. Genes Dev 9: 1149-1163, 1995.
21. Macleod KF, Sherry N, Hannon G, Beach D, Tokino T, Kinzler K, Vogelstein B, Jacks T: p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev 9: 935-944, 1995.
22. Yoshida K, Murohashi I, Hirashima K: p53-independent induction of p21 (WAF1/CIP1) during differentiation of HL-60 cells by tumor necrosis factor alpha. Int J Hemato 65: 41-48, 1996.
23. Hetts SW: To die or not to die: an overview of apoptosis and its role in disease. JAMA 79: 300-307, 1998.
24. Siavoshian S, Blottiere HM, Cherbut C, Galmiche J-P: Butyrate stimulates cyclin D and p21 and inhibits cyclin-dependent kinase 2 expression in HT-29 colonic epithelial cells. Biochem Biophys Res Commun 232: 169-172, 1997.
25. Hague A, Diaz GD, Hicks DJ, Krajewski S, Reed JC, Paraskeva C: bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis. Int J Cancer 72: 898-905, 1997.
26. Barranco SC, Weintraub B, Maclean KK, Beasley EG, Jenkins VK, Townsend CM Jr: Relationship between glutathione levels and drug or radiation sensitivities in human gastric cancer cell lines in vitro. Invest New Drugs 9: 29-36, 1991.
27. Petronini PG, Urbani S, Alfieri R, Borgheti AF, Guidotti GG: Cell susceptibility to apoptosis by glutamine deprivation and rescue: survival and apoptotic death in cultured lymphoma-leukemia cell lines. J Cell Physiol 169: 175-185, 1996.
28. Litvak DA, Papaconstantinou HT, Hwang KO, Kim HJ, Evers BM, Townsend CM Jr: Inhibition of gastric cancer by camptothecin involves apoptosis and multiple cellular pathways. Surgery 126: 223-230, 1999.
29. Evers BM, Ko TC, Li J, Thompson EA: Cell cycle protein suppression and p21 induction in differentiating SIIA cells. Am J Physiol 271: G722-G727, 1996.
30. Nita ME, Nagawa H, Tominaga O, Tsuno N, Fujii S, Sasaki S, Fu CG, Takenoue T, Tsuruo, T, Muto T: 5-Flurouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins. Br J Cancer 78: 986-992, 1998.
31. Kondo S, Shinomura Y, Kanayama S, Higashimoto Y, Kiyohara T, Zushi S, Kitamura S, Ueyama H, Matsuzawa YI: Modulation of apoptosis by endogenous Bcl-xL expression in MKN45 human gastric cancer cells. Oncogene 17: 2585-2591, 1998.
32. Chen G, Sordillo EM, Ramey WG, Reidy J, Holt PR, Krajewski S, Reed JC, Blaser MJ, Moss SF: Apoptosis in gastric epithelial cells is induced by Helicobacter pylori and accompanied by increased expression of BAK. Biochem Biophys Res Commun 239: 626-632, 1997.
33. Cordel S, Dupas B, Douillard JY, Meflah K: Interleukin-2/sodium butyrate treatment cures rats bearing liver tumors after acquired 5-fluorouracil resistance. Int J Cancer 78: 735-739, 1998.
34. Cappellini MD, Graziadei G, Ciceri L, Comino A, Bianchi P, Pomati M, Fiorelli G: Butyrate trials. Ann NY Acad Sci 850: 110-119, 1998.