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Volumn 19, Issue 4 B, 1999, Pages 2901-2906

Inhibition of proliferation, invasion and adhesion of liver cancer cells by 5-azacytidine and butyrate

Author keywords

5 Azacytidine; Butyrate; Cell cycle; Cyclin dependent kinase inhibitors

Indexed keywords

AZACITIDINE; BUTYRIC ACID; PROTEIN P21; PROTEIN P27; PROTEIN P53;

EID: 0033404082     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (8)

References (46)
  • 2
    • 0029153828 scopus 로고
    • Etiology and pathogenesis of hepatocellular carcinoma
    • Tsai S-L and Liaw Y-F: Etiology and pathogenesis of hepatocellular carcinoma. Dig Surg 12: 7-15, 1995.
    • (1995) Dig Surg , vol.12 , pp. 7-15
    • Tsai, S.-L.1    Liaw, Y.-F.2
  • 3
    • 0343046394 scopus 로고
    • Estimates of the world wild wide incidence of 18 major cancers
    • Parkin DM, Piani P and Ferlay J: Estimates of the world wild wide incidence of 18 major cancers. Int J Cancer 54: 494-622, 1993.
    • (1993) Int J Cancer , vol.54 , pp. 494-622
    • Parkin, D.M.1    Piani, P.2    Ferlay, J.3
  • 4
    • 0028954744 scopus 로고
    • Hepatocellular carcinoma
    • Sherman M: Hepatocellular carcinoma. Gastroenterologist 3: 55-66, 1995.
    • (1995) Gastroenterologist , vol.3 , pp. 55-66
    • Sherman, M.1
  • 5
    • 0003010021 scopus 로고    scopus 로고
    • Cancer of the liver
    • (DeVita VT Jr, Hellman S, Rosenberg SA, eds). New York, Lippincott-Raven
    • Carr BI, Flickinger JC and Lotze MT: Cancer of the liver. In: Cancer - principles & practice of oncology (DeVita VT Jr, Hellman S, Rosenberg SA, eds). New York, Lippincott-Raven 1997, pp 1087-1114.
    • (1997) Cancer - Principles & Practice of Oncology , pp. 1087-1114
    • Carr, B.I.1    Flickinger, J.C.2    Lotze, M.T.3
  • 6
    • 0023936352 scopus 로고
    • Clinical trials in primary hepatocellular carcinoma: Current status and future directions
    • Nerenstone SR, Ihde DC and Friedman MA: Clinical trials in primary hepatocellular carcinoma: current status and future directions. Cancer Treat Rev 15: 1-31, 1988.
    • (1988) Cancer Treat Rev , vol.15 , pp. 1-31
    • Nerenstone, S.R.1    Ihde, D.C.2    Friedman, M.A.3
  • 7
    • 0025083071 scopus 로고
    • Critical factors in the biology of human cancer metastasis: Twenty-eight GHA Clowes Memorial Award Lecture
    • Fidler IJ: Critical factors in the biology of human cancer metastasis: Twenty-eight GHA Clowes Memorial Award Lecture. Cancer Res 50: 6130-6138, 1990.
    • (1990) Cancer Res , vol.50 , pp. 6130-6138
    • Fidler, I.J.1
  • 8
    • 0027938207 scopus 로고
    • Ordering S phase and M phase in the cell cycle
    • Nurse P: Ordering S phase and M phase in the cell cycle. Cell 79: 547-550, 1994.
    • (1994) Cell , vol.79 , pp. 547-550
    • Nurse, P.1
  • 9
    • 0024473604 scopus 로고
    • G1 events and regulation of cell proliferation
    • Pardee AB: G1 events and regulation of cell proliferation. Science 246: 603-608, 1989.
    • (1989) Science , vol.246 , pp. 603-608
    • Pardee, A.B.1
  • 10
    • 0029317904 scopus 로고
    • Cyclin-dependent protein kinases: Key regulators of the eukaryotic cell cycle
    • Nigg EA: Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle. Bioessays 17: 471-480, 1995.
    • (1995) Bioessays , vol.17 , pp. 471-480
    • Nigg, E.A.1
  • 11
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • Sherr CJ and Roberts JM: Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 9: 1149-1163, 1995.
    • (1995) Genes Dev , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.M.2
  • 12
    • 0028075611 scopus 로고
    • Cdk inhibitors: On the threshold of checkpoints and development
    • Elledge SJ and Harper JW: Cdk inhibitors: on the threshold of checkpoints and development. Curr Opin Cell Biol 6: 847-852, 1994.
    • (1994) Curr Opin Cell Biol , vol.6 , pp. 847-852
    • Elledge, S.J.1    Harper, J.W.2
  • 13
    • 0028963841 scopus 로고
    • p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
    • Macleod KF, Sherry N, Hannon G, et al: p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev 9: 935-944, 1995.
    • (1995) Genes Dev , vol.9 , pp. 935-944
    • Macleod, K.F.1    Sherry, N.2    Hannon, G.3
  • 14
    • 0030560784 scopus 로고    scopus 로고
    • p53-independent induction of p21 (WAF1/CIP1 ) during differentiation of HL-60 cells by tumor necrosis factor alpha
    • Yoshida K, Murohashi I and Hiroshima K: p53-independent induction of p21 (WAF1/CIP1 ) during differentiation of HL-60 cells by tumor necrosis factor alpha. Int J Hematol 65: 41-48, 1996.
    • (1996) Int J Hematol , vol.65 , pp. 41-48
    • Yoshida, K.1    Murohashi, I.2    Hiroshima, K.3
  • 16
    • 0031825739 scopus 로고    scopus 로고
    • Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21waf1/cip1 and p27kip1
    • Litvak DA, Evers BM, Hwang KO, Hellmich MR, Ko TC and Townsend CM Jr: Butyrate-induced differentiation of Caco-2 cells is associated with apoptosis and early induction of p21waf1/cip1 and p27kip1. Surgery 124: 161-170, 1998.
    • (1998) Surgery , vol.124 , pp. 161-170
    • Litvak, D.A.1    Evers, B.M.2    Hwang, K.O.3    Hellmich, M.R.4    Ko, T.C.5    Townsend C.M., Jr.6
  • 17
    • 0018581647 scopus 로고
    • Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine
    • Taylor SM and Jones PA: Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell 17: 771-779, 1979.
    • (1979) Cell , vol.17 , pp. 771-779
    • Taylor, S.M.1    Jones, P.A.2
  • 18
    • 0020032366 scopus 로고
    • Inhibition of DNA methyltransferases and induction of Friend crythroleukemia cell differentiation by 5-azacytidine and 5-aza-2′-deoxycytidine
    • Creusot F, Acs G, and Christman JK: Inhibition of DNA methyltransferases and induction of Friend crythroleukemia cell differentiation by 5-azacytidine and 5-aza-2′-deoxycytidine. J Biol Chem 257: 2041-2048, 1982.
    • (1982) J Biol Chem , vol.257 , pp. 2041-2048
    • Creusot, F.1    Acs, G.2    Christman, J.K.3
  • 19
    • 0018860957 scopus 로고
    • Cellular differentiation, cytidine analogs and DNA methylation
    • Jones PA and Taylor SM: Cellular differentiation, cytidine analogs and DNA methylation. Cell 20: 85-93, 1980.
    • (1980) Cell , vol.20 , pp. 85-93
    • Jones, P.A.1    Taylor, S.M.2
  • 20
    • 0027243484 scopus 로고
    • 5-aza-2′deoxycytidine (Decitabine) and 5-azacytidine in the treatment of acute myeloid leukemias and myelodysplastic syndromes: Past, present and future trends
    • Pinto A and Zagonel V: 5-aza-2′deoxycytidine (Decitabine) and 5-azacytidine in the treatment of acute myeloid leukemias and myelodysplastic syndromes: past, present and future trends. Leukemia 7: 51-60, 1993.
    • (1993) Leukemia , vol.7 , pp. 51-60
    • Pinto, A.1    Zagonel, V.2
  • 21
    • 0029867233 scopus 로고    scopus 로고
    • New chemotherapeutic agents in acute myeloid leukemia
    • Kantarjian HM, Estey EH and Keating MA: New chemotherapeutic agents in acute myeloid leukemia. Leukemia 10: 4-6, 1996.
    • (1996) Leukemia , vol.10 , pp. 4-6
    • Kantarjian, H.M.1    Estey, E.H.2    Keating, M.A.3
  • 22
    • 0030064474 scopus 로고    scopus 로고
    • Pilot study of 5-azacytidine (5-AZA) and carboplatin (CBDCA) in patients with relapsed/refractory leukemia
    • Kritz AD, Raptis G and Menendez-Botet C: Pilot study of 5-azacytidine (5-AZA) and carboplatin (CBDCA) in patients with relapsed/refractory leukemia. Am J Hematol 51: 117-121, 1996.
    • (1996) Am J Hematol , vol.51 , pp. 117-121
    • Kritz, A.D.1    Raptis, G.2    Menendez-Botet, C.3
  • 23
    • 0028073007 scopus 로고
    • Effects of differentiation-inducing agents on purine nucleotide metabolism in an ovarian cancer cell line
    • Zoref-Shani E, Lavie R, Bromberg Y, et al: Effects of differentiation-inducing agents on purine nucleotide metabolism in an ovarian cancer cell line. J Cancer Res Clin Oncol 120: 717-722, 1994.
    • (1994) J Cancer Res Clin Oncol , vol.120 , pp. 717-722
    • Zoref-Shani, E.1    Lavie, R.2    Bromberg, Y.3
  • 24
    • 0030601209 scopus 로고    scopus 로고
    • Sodium butyrate induces tyrosine phosphorylation and activation of MAP kinase (ERK-1) in human K562 cells
    • Rivero JA and Adunyah SE: Sodium butyrate induces tyrosine phosphorylation and activation of MAP kinase (ERK-1) in human K562 cells. Biochem Biophys Res Com 224: 796-801, 1996.
    • (1996) Biochem Biophys Res Com , vol.224 , pp. 796-801
    • Rivero, J.A.1    Adunyah, S.E.2
  • 25
    • 0027970153 scopus 로고
    • Growth and intestinal differentiation are independently regulated in HT29 colon cancer cells
    • Schroy PC, Rustgi AK, Ikonomu E, et al: Growth and intestinal differentiation are independently regulated in HT29 colon cancer cells. J Cell Physiol 161: 111-123, 1994.
    • (1994) J Cell Physiol , vol.161 , pp. 111-123
    • Schroy, P.C.1    Rustgi, A.K.2    Ikonomu, E.3
  • 26
    • 0031577480 scopus 로고    scopus 로고
    • Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21Waf/Cipl in p53-independent manner
    • Xiao H, Hasegawa T, Miyaishi O, Ohkusu K and Isobe KI: Sodium butyrate induces NIH3T3 cells to senescence-like state and enhances promoter activity of p21Waf/Cipl in p53-independent manner. Biochem Biophys Res Com 237: 457-460, 1997.
    • (1997) Biochem Biophys Res Com , vol.237 , pp. 457-460
    • Xiao, H.1    Hasegawa, T.2    Miyaishi, O.3    Ohkusu, K.4    Isobe, K.I.5
  • 27
    • 0028859161 scopus 로고
    • Apoptosis in colorectal tumor cell: Induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate
    • Hague A, Elder DJ, Hicks DJ and Paraskeva C: Apoptosis in colorectal tumor cell: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate. Int J Cancer 60: 400-406, 1995.
    • (1995) Int J Cancer , vol.60 , pp. 400-406
    • Hague, A.1    Elder, D.J.2    Hicks, D.J.3    Paraskeva, C.4
  • 28
    • 0030741385 scopus 로고    scopus 로고
    • Apoptotic death in adenocarcinoma cell lines by butyrate and other histone deacetylase inhibitors
    • McBain JA, Eastman A, Novel CS and Mueller GC: Apoptotic death in adenocarcinoma cell lines by butyrate and other histone deacetylase inhibitors. Biochem Pharmacol 53: 1357-1368, 1997.
    • (1997) Biochem Pharmacol , vol.53 , pp. 1357-1368
    • McBain, J.A.1    Eastman, A.2    Novel, C.S.3    Mueller, G.C.4
  • 29
    • 0029885817 scopus 로고    scopus 로고
    • Potentiation of sodium butyrate-induced apoptosis by vanadate in human promyelocytic leukemia cell line HL-60
    • Chang ST and Yung BY: Potentiation of sodium butyrate-induced apoptosis by vanadate in human promyelocytic leukemia cell line HL-60, Biochem Biophys Res Commun 221: 594-601, 1996.
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 594-601
    • Chang, S.T.1    Yung, B.Y.2
  • 31
    • 0028809535 scopus 로고
    • Induction of apoptosis by sodium butyrate in the human Y-79 retinoblastoma cell line
    • Conway RM, Madigan MC, Penfold PL and Billson FA: Induction of apoptosis by sodium butyrate in the human Y-79 retinoblastoma cell line. Oncol Res 7: 289-297, 1995.
    • (1995) Oncol Res , vol.7 , pp. 289-297
    • Conway, R.M.1    Madigan, M.C.2    Penfold, P.L.3    Billson, F.A.4
  • 32
    • 0032452623 scopus 로고    scopus 로고
    • Effects of 5-azacytidine and butyrate on differentiation and apoptosis of hepatic cancer cell lines
    • Wang X-M, Wang X, Li J and Evers BM. Effects of 5-azacytidine and butyrate on differentiation and apoptosis of hepatic cancer cell lines. Ann Surg 227: 922-931, 1998.
    • (1998) Ann Surg , vol.227 , pp. 922-931
    • Wang, X.-M.1    Wang, X.2    Li, J.3    Evers, B.M.4
  • 33
    • 0018718742 scopus 로고
    • Controlled synthesis of HbsAg in a differentiated human liver carcinoma-derived cell line
    • Aden DP, Fogel A, Plotkin S, Damjanov I and Knowles BB: Controlled synthesis of HbsAg in a differentiated human liver carcinoma-derived cell line. Nature 282: 615-616, 1979.
    • (1979) Nature , vol.282 , pp. 615-616
    • Aden, D.P.1    Fogel, A.2    Plotkin, S.3    Damjanov, I.4    Knowles, B.B.5
  • 34
    • 0019332750 scopus 로고
    • Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen
    • Knowles BB, Howe CC and Aden DP: Human hepatocellular carcinoma cell lines secrete the major plasma proteins and hepatitis B surface antigen. Science 209: 497-499, 1980.
    • (1980) Science , vol.209 , pp. 497-499
    • Knowles, B.B.1    Howe, C.C.2    Aden, D.P.3
  • 35
    • 0023187867 scopus 로고
    • A rapid in vitro assay for quantitating the invasive potential of tumor cells
    • Albini A, Iwamoto Y, Kleinman HK, et al: A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 47: 3239-3245, 1987.
    • (1987) Cancer Res , vol.47 , pp. 3239-3245
    • Albini, A.1    Iwamoto, Y.2    Kleinman, H.K.3
  • 36
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1987.
    • (1987) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 38
    • 0026022059 scopus 로고
    • Molecular analysis of the p53 alleles in primary hepatocellular carcinomas and cell lines
    • Hosono S, Lee CS, Chou MJ, et al: Molecular analysis of the p53 alleles in primary hepatocellular carcinomas and cell lines. Oncogene 6: 237-243, 1991.
    • (1991) Oncogene , vol.6 , pp. 237-243
    • Hosono, S.1    Lee, C.S.2    Chou, M.J.3
  • 39
    • 0028820762 scopus 로고
    • The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo
    • Yang Z-Y, Perkins ND, Ohno T, Nabel EG and Nabel GJ: The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo. Nat Med 1: 1052-1056, 1945.
    • (1945) Nat Med , vol.1 , pp. 1052-1056
    • Yang, Z.-Y.1    Perkins, N.D.2    Ohno, T.3    Nabel, E.G.4    Nabel, G.J.5
  • 41
    • 0028849274 scopus 로고
    • p21 is necessary for the p53-mediated G1 arrest in human cancer cells
    • Waldman T, Kinzler KW and Vogelstein B: p21 is necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res 55: 5187-5190, 1995.
    • (1995) Cancer Res , vol.55 , pp. 5187-5190
    • Waldman, T.1    Kinzler, K.W.2    Vogelstein, B.3
  • 42
    • 0029829031 scopus 로고    scopus 로고
    • Upregulation and functional role of p21waf1/cip1 during growth arrest of human breast carcinoma MCF-7 cells by phenylacetate
    • Gorospe M, Shack S, Guyton KZ, Samid D and Holbrook NJ: Upregulation and functional role of p21waf1/cip1 during growth arrest of human breast carcinoma MCF-7 cells by phenylacetate. Cell Growth Differ 7: 1609-1615, 1996.
    • (1996) Cell Growth Differ , vol.7 , pp. 1609-1615
    • Gorospe, M.1    Shack, S.2    Guyton, K.Z.3    Samid, D.4    Holbrook, N.J.5
  • 43
    • 0342612256 scopus 로고    scopus 로고
    • The cyclin-dependent kinase inhibitor p21 as a target for differentiation therapy
    • Manfredi JJ, Tang H-Y and Waxman S: The cyclin-dependent kinase inhibitor p21 as a target for differentiation therapy. Mol Cell Differ 4: 33-45, 1996.
    • (1996) Mol Cell Differ , vol.4 , pp. 33-45
    • Manfredi, J.J.1    Tang, H.-Y.2    Waxman, S.3
  • 44
    • 0030894787 scopus 로고    scopus 로고
    • The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas
    • Tan P, Cady B, Wanner M, et al: The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas. Cancer Res 57: 1259-1263, 1997.
    • (1997) Cancer Res , vol.57 , pp. 1259-1263
    • Tan, P.1    Cady, B.2    Wanner, M.3
  • 45
    • 0030855876 scopus 로고    scopus 로고
    • Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas
    • Yasui W, Kudo Y, Semba S, Yokozaki H and Tahara E: Reduced expression of cyclin-dependent kinase inhibitor p27Kip1 is associated with advanced stage and invasiveness of gastric carcinomas. Jap J Cancer Res 88: 625-629, 1997.
    • (1997) Jap J Cancer Res , vol.88 , pp. 625-629
    • Yasui, W.1    Kudo, Y.2    Semba, S.3    Yokozaki, H.4    Tahara, E.5
  • 46
    • 0030947356 scopus 로고    scopus 로고
    • High level expression of p27 (kip1) and cyclin D1 in some human breast cancer cells: Inverse correlation between the expression of p27 (kip1) and degree of malignancy in human breast and colorectal cancers
    • Fredersdorf S, Burns J, Milne AM, et al: High level expression of p27 (kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27 (kip1) and degree of malignancy in human breast and colorectal cancers. Proc Natl Acad Sci USA 94: 6380-6385, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6380-6385
    • Fredersdorf, S.1    Burns, J.2    Milne, A.M.3


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