메뉴 건너뛰기




Volumn 250, Issue 3, 2003, Pages 15-24

New insights into Parkinson's disease

Author keywords

synuclein; MPTP; Parkin; Proteasome; Synphilin 1; Ubiquitin

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALPHA SYNUCLEIN; DIAMORPHINE; DJ 1 PROTEIN; FUNGICIDE; HERBICIDE; HYDROLASE; LEVODOPA; LIGASE; MUTANT PROTEIN; PARKIN; PESTICIDE; PROTEASOME; PROTEIN; ROTENONE; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

EID: 0142125350     PISSN: 09391517     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (55)

References (106)
  • 4
    • 0033363646 scopus 로고    scopus 로고
    • The septin CDCrel-1 binds syntaxin and inhibits exocytosis
    • Beites CL, Xie H, Bowser R, Trimble WS (1999) The septin CDCrel-1 binds syntaxin and inhibits exocytosis. Nat Neurosci 2:434-439
    • (1999) Nat Neurosci , vol.2 , pp. 434-439
    • Beites, C.L.1    Xie, H.2    Bowser, R.3    Trimble, W.S.4
  • 9
    • 0031668924 scopus 로고    scopus 로고
    • The early diagnosis of Parkinson's disease
    • Brooks DJ (1998) The early diagnosis of Parkinson's disease. Ann Neurol 44:S10-S18
    • (1998) Ann Neurol , vol.44
    • Brooks, D.J.1
  • 11
    • 2942618660 scopus 로고    scopus 로고
    • The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders
    • Chung KK, Dawson VL, Dawson TM (2001) The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders. Trends Neurosci 24:S7-S14
    • (2001) Trends Neurosci , vol.24
    • Chung, K.K.1    Dawson, V.L.2    Dawson, T.M.3
  • 12
    • 0034776095 scopus 로고    scopus 로고
    • Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease
    • Chung KK, Zhang Y, Lim KL, Tanaka Y, Huang H, Gao J, Ross CA, Dawson VL, Dawson TM (2001) Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat Med 7:1144-1150
    • (2001) Nat Med , vol.7 , pp. 1144-1150
    • Chung, K.K.1    Zhang, Y.2    Lim, K.L.3    Tanaka, Y.4    Huang, H.5    Gao, J.6    Ross, C.A.7    Dawson, V.L.8    Dawson, T.M.9
  • 13
    • 0033215063 scopus 로고    scopus 로고
    • Synucleins in synaptic plasticity and neurodegenerative disorders
    • Clayton DF, George JM (1999) Synucleins in synaptic plasticity and neurodegenerative disorders. J Neurosci Res 58:120-129
    • (1999) J Neurosci Res , vol.58 , pp. 120-129
    • Clayton, D.F.1    George, J.M.2
  • 15
    • 0037130450 scopus 로고    scopus 로고
    • Animal models of PD: Pieces of the same puzzle?
    • Dawson TM, Mandir AS, Lee MK (2002) Animal models of PD: pieces of the same puzzle? Neuron 35:219-222
    • (2002) Neuron , vol.35 , pp. 219-222
    • Dawson, T.M.1    Mandir, A.S.2    Lee, M.K.3
  • 17
    • 0035830913 scopus 로고    scopus 로고
    • Alpha-synuclein is phosphorylated by members of the Src family of protein-tyrosine kinases
    • Ellis CE, Schwartzberg PL, Grider TL, Fink DW, Nussbaum RL (2001) alpha-synuclein is phosphorylated by members of the Src family of protein-tyrosine kinases. J Biol Chem 276: 3879-3884
    • (2001) J Biol Chem , vol.276 , pp. 3879-3884
    • Ellis, C.E.1    Schwartzberg, P.L.2    Grider, T.L.3    Fink, D.W.4    Nussbaum, R.L.5
  • 22
    • 0034704752 scopus 로고    scopus 로고
    • A Drosophila model of Parkinson's disease
    • Feany MB, Bender WW (2000) A Drosophila model of Parkinson's disease. Nature 404:394-398
    • (2000) Nature , vol.404 , pp. 394-398
    • Feany, M.B.1    Bender, W.W.2
  • 23
    • 0036196860 scopus 로고    scopus 로고
    • A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1
    • Funayama M, Hasegawa K, Kowa H, Saito M, Tsuji S, Obata F (2002) A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2- q13.1. Ann Neurol 51:296-301
    • (2002) Ann Neurol , vol.51 , pp. 296-301
    • Funayama, M.1    Hasegawa, K.2    Kowa, H.3    Saito, M.4    Tsuji, S.5    Obata, F.6
  • 25
    • 0032937059 scopus 로고    scopus 로고
    • Diagnostic criteria for Parkinson disease
    • Gelb DJ, Oliver E, Gilman S (1999) Diagnostic criteria for Parkinson disease. Arch Neurol 56:33-39
    • (1999) Arch Neurol , vol.56 , pp. 33-39
    • Gelb, D.J.1    Oliver, E.2    Gilman, S.3
  • 27
    • 0037118259 scopus 로고    scopus 로고
    • Neuronal alpha-synucleinopathy with severe movement disorder in mice ex-pressing A53T human alpha-synuclein
    • Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM (2002) Neuronal alpha-synucleinopathy with severe movement disorder in mice ex-pressing A53T human alpha-synuclein. Neuron 34:521-533
    • (2002) Neuron , vol.34 , pp. 521-533
    • Giasson, B.I.1    Duda, J.E.2    Quinn, S.M.3    Zhang, B.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 28
    • 0036654314 scopus 로고    scopus 로고
    • Genetics of parkinsonism
    • Gwinn-Hardy K (2002) Genetics of parkinsonism. Mov Disord 17:645-656
    • (2002) Mov Disord , vol.17 , pp. 645-656
    • Gwinn-Hardy, K.1
  • 29
    • 0034069848 scopus 로고    scopus 로고
    • Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p
    • Berl
    • Gwinn-Hardy K, Mehta ND, Farrer M, Maraganore D, Muenter M, Yen SH, Hardy J, Dickson DW (2000) Distinctive neuropathology revealed by alpha-synuclein antibodies in hereditary parkinsonism and dementia linked to chromosome 4p. Acta Neuropathol (Berl) 99:663-672
    • (2000) Acta Neuropathol , vol.99 , pp. 663-672
    • Gwinn-Hardy, K.1    Mehta, N.D.2    Farrer, M.3    Maraganore, D.4    Muenter, M.5    Yen, S.H.6    Hardy, J.7    Dickson, D.W.8
  • 31
    • 0032491408 scopus 로고    scopus 로고
    • Genetic classification of primary neurodegenerative disease
    • Hardy J, Gwinn-Hardy K (1998) Genetic classification of primary neurodegenerative disease. Science 282: 1075-1079
    • (1998) Science , vol.282 , pp. 1075-1079
    • Hardy, J.1    Gwinn-Hardy, K.2
  • 33
    • 0030875612 scopus 로고    scopus 로고
    • Autosomal dominant familial Parkinson disease: Older onset of age, and good response to levodopa therapy
    • Hasegawa K, Kowa H (1997) Autosomal dominant familial Parkinson disease: older onset of age, and good response to levodopa therapy. Eur Neurol 38:39-43
    • (1997) Eur Neurol , vol.38 , pp. 39-43
    • Hasegawa, K.1    Kowa, H.2
  • 35
    • 0033577159 scopus 로고    scopus 로고
    • Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro
    • Hashimoto M, Hsu LJ, Xia Y, Takeda A, Sisk A, Sundsmo M, Masliah E (1999) Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro. Neuroreport 10: 717-721
    • (1999) Neuroreport , vol.10 , pp. 717-721
    • Hashimoto, M.1    Hsu, L.J.2    Xia, Y.3    Takeda, A.4    Sisk, A.5    Sundsmo, M.6    Masliah, E.7
  • 36
    • 0035950270 scopus 로고    scopus 로고
    • Beta-synuclein inhibits alpha-synuclein aggregation: A possible role as an anti-parkinsonian factor
    • Hashimoto M, Rockenstein E, Mante M, Mallory M, Masliah E (2001) beta-synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor. Neuron 32: 213-223
    • (2001) Neuron , vol.32 , pp. 213-223
    • Hashimoto, M.1    Rockenstein, E.2    Mante, M.3    Mallory, M.4    Masliah, E.5
  • 40
    • 0033103726 scopus 로고    scopus 로고
    • Identification and characterization of a novel protein that regulates RNA-protein interaction
    • Hod Y, Pentyala SN, Whyard TC, El-Maghrabi MR (1999) Identification and characterization of a novel protein that regulates RNA-protein interaction. J Cell Biochem 72:435-444
    • (1999) J Cell Biochem , vol.72 , pp. 435-444
    • Hod, Y.1    Pentyala, S.N.2    Whyard, T.C.3    El-Maghrabi, M.R.4
  • 41
    • 0033767459 scopus 로고    scopus 로고
    • Parkin is associated with actin filaments in neuronal and nonneural cells
    • Huynh DP, Scoles DR, Ho TH, Del Bigio MR, Pulst SM (2000) Parkin is associated with actin filaments in neuronal and nonneural cells. Ann Neurol 48:737-744
    • (2000) Ann Neurol , vol.48 , pp. 737-744
    • Huynh, D.P.1    Scoles, D.R.2    Ho, T.H.3    Del Bigio, M.R.4    Pulst, S.M.5
  • 42
    • 0037047311 scopus 로고    scopus 로고
    • Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome
    • Hyun DH, Lee M, Hattori N, Kubo S, Mizuno Y, Halliwell B, Jenner P (2002) Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome. J Biol Chem 277:28572-28577
    • (2002) J Biol Chem , vol.277 , pp. 28572-28577
    • Hyun, D.H.1    Lee, M.2    Hattori, N.3    Kubo, S.4    Mizuno, Y.5    Halliwell, B.6    Jenner, P.7
  • 43
    • 0036345454 scopus 로고    scopus 로고
    • CHIP is associated with parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity
    • Imai Y, Soda M, Hatakeyama S, Akagi T, Hashikawa T, Nakayama KI, Takahashi R (2002) CHIP is associated with parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol Cell 10: 55-67
    • (2002) Mol Cell , vol.10 , pp. 55-67
    • Imai, Y.1    Soda, M.2    Hatakeyama, S.3    Akagi, T.4    Hashikawa, T.5    Nakayama, K.I.6    Takahashi, R.7
  • 44
    • 0035967883 scopus 로고    scopus 로고
    • An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
    • Imai Y, Soda M, Inoue H, Hattori N, Mizuno Y, Takahashi R (2001) An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 105:891-902
    • (2001) Cell , vol.105 , pp. 891-902
    • Imai, Y.1    Soda, M.2    Inoue, H.3    Hattori, N.4    Mizuno, Y.5    Takahashi, R.6
  • 45
    • 0034680913 scopus 로고    scopus 로고
    • Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
    • Imai Y, Soda M, Takahashi R (2000) Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J Biol Chem 275:35661-35664
    • (2000) J Biol Chem , vol.275 , pp. 35661-35664
    • Imai, Y.1    Soda, M.2    Takahashi, R.3
  • 46
    • 0030015934 scopus 로고    scopus 로고
    • Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism
    • Ishikawa A, Tsuji S (1996) Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism. Neurology 47: 160-166
    • (1996) Neurology , vol.47 , pp. 160-166
    • Ishikawa, A.1    Tsuji, S.2
  • 51
    • 0020680904 scopus 로고
    • Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
    • Langston JW, Ballard P, Tetrud JW, Irwin I (1983) Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219: 979-980
    • (1983) Science , vol.219 , pp. 979-980
    • Langston, J.W.1    Ballard, P.2    Tetrud, J.W.3    Irwin, I.4
  • 52
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
    • Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D (1999) Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol 46:598-605
    • (1999) Ann Neurol , vol.46 , pp. 598-605
    • Langston, J.W.1    Forno, L.S.2    Tetrud, J.3    Reeves, A.G.4    Kaplan, J.A.5    Karluk, D.6
  • 53
    • 0032502276 scopus 로고    scopus 로고
    • Substrate specificity of deubiquitinating enzymes: Ubiquitin C-terminal hydrolases
    • Larsen CN, Krantz BA, Wilkinson KD (1998) Substrate specificity of deubiquitinating enzymes: ubiquitin C-terminal hydrolases. Biochemistry 37: 3358-3368
    • (1998) Biochemistry , vol.37 , pp. 3358-3368
    • Larsen, C.N.1    Krantz, B.A.2    Wilkinson, K.D.3
  • 55
    • 0037173006 scopus 로고    scopus 로고
    • Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala- 53 → Thr mutation causes neurodegenerative disease with alpha- synuclein aggregation in transgenic mice
    • Lee MK, Stirling W, Xu Y, Xu X, Qui D, Mandir AS, Dawson TM, Copeland NG, Jenkins NA, Price DL (2002) Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala- 53 → Thr mutation causes neurodegenerative disease with alpha- synuclein aggregation in transgenic mice. Proc Natl Acad Sci USA 99:8968-8973
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8968-8973
    • Lee, M.K.1    Stirling, W.2    Xu, Y.3    Xu, X.4    Qui, D.5    Mandir, A.S.6    Dawson, T.M.7    Copeland, N.G.8    Jenkins, N.A.9    Price, D.L.10
  • 58
    • 0037131567 scopus 로고    scopus 로고
    • The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility
    • Liu Y, Fallon L, Lashuel HA, Liu Z, Lansbury PT, Jr. (2002) The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinson's disease susceptibility. Cell 111:209-218
    • (2002) Cell , vol.111 , pp. 209-218
    • Liu, Y.1    Fallon, L.2    Lashuel, H.A.3    Liu, Z.4    Lansbury P.T., Jr.5
  • 62
    • 0035834076 scopus 로고    scopus 로고
    • Beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease
    • Masliah E, Rockenstein E, Veinbergs I, Sagara Y, Mallory M, Hashimoto M, Mucke L (2001) beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease. Proc Natl Acad Sci USA 98:12245-12250
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12245-12250
    • Masliah, E.1    Rockenstein, E.2    Veinbergs, I.3    Sagara, Y.4    Mallory, M.5    Hashimoto, M.6    Mucke, L.7
  • 64
    • 0035692636 scopus 로고    scopus 로고
    • DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin
    • Mitsumoto A, Nakagawa Y (2001) DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin. Free Radic Res 35:885-893
    • (2001) Free Radic Res , vol.35 , pp. 885-893
    • Mitsumoto, A.1    Nakagawa, Y.2
  • 65
    • 0034906096 scopus 로고    scopus 로고
    • Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat
    • Mitsumoto A, Nakagawa Y, Takeuchi A, Okawa K, Iwamatsu A, Takanezawa Y (2001) Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat. Free Radic Res 35: 301-310
    • (2001) Free Radic Res , vol.35 , pp. 301-310
    • Mitsumoto, A.1    Nakagawa, Y.2    Takeuchi, A.3    Okawa, K.4    Iwamatsu, A.5    Takanezawa, Y.6
  • 66
    • 0031719122 scopus 로고    scopus 로고
    • Advanced glycation end products in neurodegeneration: More than early markers of oxidative stress?
    • Munch G, Gerlach M, Sian J, Wong A, Riederer P (1998) Advanced glycation end products in neurodegeneration: more than early markers of oxidative stress? Ann Neurol 44:S85-S88
    • (1998) Ann Neurol , vol.44
    • Munch, G.1    Gerlach, M.2    Sian, J.3    Wong, A.4    Riederer, P.5
  • 70
    • 0032936755 scopus 로고    scopus 로고
    • Etiology and pathogenesis of Parkinson's disease
    • Olanow CW, Tatton WG (1999) Etiology and pathogenesis of Parkinson's disease. Annu Rev Neurosci 22: 123-144
    • (1999) Annu Rev Neurosci , vol.22 , pp. 123-144
    • Olanow, C.W.1    Tatton, W.G.2
  • 77
    • 0037189591 scopus 로고    scopus 로고
    • Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein
    • Ribeiro CS, Carneiro K, Ross CA, Menezes JR, Engelender S (2002) Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein. J Biol Chem 277:23927-23933
    • (2002) J Biol Chem , vol.277 , pp. 23927-23933
    • Ribeiro, C.S.1    Carneiro, K.2    Ross, C.A.3    Menezes, J.R.4    Engelender, S.5
  • 81
    • 0037456578 scopus 로고    scopus 로고
    • The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease
    • Sharon R, Bar-Joseph I, Frosch MP, Walsh DM, Hamilton JA, Selkoe DJ (2003) The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease. Neuron 37: 583-595
    • (2003) Neuron , vol.37 , pp. 583-595
    • Sharon, R.1    Bar-Joseph, I.2    Frosch, M.P.3    Walsh, D.M.4    Hamilton, J.A.5    Selkoe, D.J.6
  • 82
    • 0037104723 scopus 로고    scopus 로고
    • An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
    • Sherer TB, Betarbet R, Stout AK, Lund S, Baptista M, Panov AV, Cookson MR, Greenamyre JT (2002) An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. J Neurosci 22: 7006-7015
    • (2002) J Neurosci , vol.22 , pp. 7006-7015
    • Sherer, T.B.1    Betarbet, R.2    Stout, A.K.3    Lund, S.4    Baptista, M.5    Panov, A.V.6    Cookson, M.R.7    Greenamyre, J.T.8
  • 85
    • 0033961490 scopus 로고    scopus 로고
    • Expression of alpha-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: Genes associated with familial Parkinson's disease
    • Solano SM, Miller DW, Augood SJ, Young AB, Penney JB, Jr. (2000) Expression of alpha-synuclein, parkin, and ubiquitin carboxy-terminal hydrolase L1 mRNA in human brain: genes associated with familial Parkinson's disease. Ann Neurol 47:201-210
    • (2000) Ann Neurol , vol.47 , pp. 201-210
    • Solano, S.M.1    Miller, D.W.2    Augood, S.J.3    Young, A.B.4    Penney J.B., Jr.5
  • 87
    • 0037422010 scopus 로고    scopus 로고
    • Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity
    • Staropoli JF, McDermott C, Martinat C, Schulman B, Demireva E, Abeliovich A (2003) Parkin is a component of an SCF-like ubiquitin ligase complex and protects postmitotic neurons from kainate excitotoxicity. Neuron 37: 735-749
    • (2003) Neuron , vol.37 , pp. 735-749
    • Staropoli, J.F.1    McDermott, C.2    Martinat, C.3    Schulman, B.4    Demireva, E.5    Abeliovich, A.6
  • 88
    • 0035894855 scopus 로고    scopus 로고
    • Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death
    • Stefanis L, Larsen KE, Rideout HJ, Sulzer D, Greene LA (2001) Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. J Neurosci 21:9549-9560
    • (2001) J Neurosci , vol.21 , pp. 9549-9560
    • Stefanis, L.1    Larsen, K.E.2    Rideout, H.J.3    Sulzer, D.4    Greene, L.A.5
  • 90
    • 0035813135 scopus 로고    scopus 로고
    • DJ-1 positively regulates the androgen receptor by impairing the binding of PI-ASx alpha to the receptor
    • Takahashi K, Taira T, Niki T, Seino C, Iguchi-Ariga SM, Ariga H (2001) DJ-1 positively regulates the androgen receptor by impairing the binding of PI-ASx alpha to the receptor. J Biol Chem 276:37556-37563
    • (2001) J Biol Chem , vol.276 , pp. 37556-37563
    • Takahashi, K.1    Taira, T.2    Niki, T.3    Seino, C.4    Iguchi-Ariga, S.M.5    Ariga, H.6
  • 91
  • 98
    • 0037957556 scopus 로고    scopus 로고
    • Engineered modeling and the secrets of Parkinson's disease
    • Vila M, Wu DC, Przedborski S (2001) Engineered modeling and the secrets of Parkinson's disease. Trends Neurosci 24:S49-S55
    • (2001) Trends Neurosci , vol.24
    • Vila, M.1    Wu, D.C.2    Przedborski, S.3
  • 99
    • 0032552851 scopus 로고    scopus 로고
    • Molecular cloning and expression of rat contraception associated protein 1 (CAP1), a protein putatively involved in fertilization
    • Wagenfeld A, Gromoll J, Cooper TG (1998) Molecular cloning and expression of rat contraception associated protein 1 (CAP1), a protein putatively involved in fertilization. Biochem Biophys Res Commun 251:545-549
    • (1998) Biochem Biophys Res Commun , vol.251 , pp. 545-549
    • Wagenfeld, A.1    Gromoll, J.2    Cooper, T.G.3
  • 105
    • 0033825627 scopus 로고    scopus 로고
    • Oxidative stress and genetics in the pathogenesis of Parkinson's disease
    • Zhang Y, Dawson VL, Dawson TM (2000) Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol Dis 7:240-250
    • (2000) Neurobiol Dis , vol.7 , pp. 240-250
    • Zhang, Y.1    Dawson, V.L.2    Dawson, T.M.3
  • 106
    • 0034700158 scopus 로고    scopus 로고
    • Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CD-Crel-1
    • Zhang Y, Gao J, Chung KK, Huang H, Dawson VL, Dawson TM (2000) Parkin functions as an E2-dependent ubiquitin-protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CD-Crel-1. Proc Natl Acad Sci USA 97: 13354-13359
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 13354-13359
    • Zhang, Y.1    Gao, J.2    Chung, K.K.3    Huang, H.4    Dawson, V.L.5    Dawson, T.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.