Nicotine injections into the ventral tegmental area increase locomotion and Fos-like immunoreactivity in the nucleus accumbens of the rat

Brain Research

Volumn 730, Issue 1-2, 1996, Pages 133-142

  Panagis, G ^a,b   Nisell, M ^a   Nomikos, G G ^a   Chergui, K ^a   Svensson, T H ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF CRETE   (Greece)

Author keywords

behavioral sensitization; dopamine; Fos immunohistochemistry; mesolimbic; nicotine; ventral tegmental area

Indexed keywords

MECAMYLAMINE; NICOTINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC SYSTEM; IMMUNOHISTOCHEMISTRY; INTRACEREBRAL DRUG ADMINISTRATION; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; ONCOGENE C FOS; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; VENTRAL TEGMENTUM;

EID: 0030593642     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(96)00432-5     Document Type: Article

References (46)

1. [1] Andersson, K., Fuxe, K., Agnati, L.F. and Eneroth, P., Effects of acute central and peripheral administration of nicotine on ascending dopamine pathways in the male rat brain. Evidence for nicotine induced increases of dopamine turnover in various telencephalic dopamine nerve terminal systems. Med. Biol., 59 (1981) 170-176.
2. [2] Benwell, M.E.M. and Balfour, D.J.K., The effects of acute and repeated nicotine treatment on nucleus accumbens dopamine and locomotor activity, Br. J. Pharmacol., 105 (1992) 849-856.
3. [3] Calabresi, P., Lacey, M.G. and North R.A., Nicotinic excitation of rat ventral tegmental area neurones in vitro studied by intracellular recording, Br. J. Pharmacol., 98 (1989) 135-140.
4. [4] Chergui, K., Nomikos, G.G., Mathé, J.M., Gonon, F. and Svensson, T.H., Burst stimulation of the medial forebrain bundle selectively increases Fos-like immunoreactivity in the limbic forebrain of the rat. Neuroscience, 72 (1996) 141-156.
5. [5] Clarke, P.B.S., Mesolimbic dopamine activation - the key to nicotine reinforcement? In The Biology of Nicotine Dependence, Wiley, Chichester (Ciba Foundation Symposium 152), 1990, pp. 153-168.
6. [6] Clarke, P.B.S., Fu, D.S., Jakubovic, A. and Fibiger, H.C., Evidence that mesolimbic dopaminergic activation underlies the locomotor stimulant action of nicotine in rats. J. Pharmacol. Exp. Ther., 246 (1988) 701-708.
7. [7] Clarke, P.B.S., Hommer, D.W., Pert, A. and Skirboll, L.R., Electrophysiological actions of nicotine on substantia nigra single units, Br. J. Pharmacol., 85 (1985) 827-835.
8. [8] Clarke, P.B.S. and Kumar, R., The effects of nicotine on locomotor activity in tolerant and non-tolerant rats. Br. J. Pharmacol., 78 (1983) 329-337.
9. [9] Clarke, P.B.S. and Pert, A., Autoradiographic evidence for nicotinic receptors on nigrostriatal and mesolimbic dopaminergic neurons, Brain Res., 348 (1985) 355-358.
10. [10] Corrigall, W.A., Understanding brain mechanisms in nicotine reinforcement, Br. J. Addict., 86 (1991) 507-510.
11. [11] Corrigall, W.A., Coen, K.M. and Adamson, K.L., Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area, Brain Res., 653 (1994) 278-284.
12. [12] Corrigall, W.A., Franklin, K.B.J., Coen, K.M. and Clarke, P.B.S., The mesolimbic dopaminergic system is implicated in the reinforcing effects of nicotine, Psychopharmacology, 107 (1992) 285-289.
13. [13] Damsma, G., Day, J. and Fibiger, H.C., Lack of tolerance to nicotine-induced dopamine release in the nucleus accumbens, Eur. J. Pharmacol., 168 (1989) 363-368.
14. [14] Ericson, E., Samuelsson, J. and Ahlenius, S., Photocell measurements of rat motor activity, J. Pharmacol. Methods, 25 (1991) 111-122
15. [15] Graybiel A.M., Moratalla R. and Robertson H.A., Amphetamine and cocaine induce drug-specific activation of the c-fos gene in striosome-matnx compartments and limbic subdivisions of the striatum, Proc. Natl. Acad. Sci. USA, 87 (1990) 6912-6916.
16. [16] Grenhoff, J., Aston-Jones, G. and Svensson, T.H., Nicotinic effects on the firing pattern of midbrain dopamine neurons, Acta Physiol. Scand., 128 (1986) 351-358.
17. [17] Grenhoff, J. and Svensson, T.H., Selective stimulation of limbic dopamine activity by nicotine. Acta Pysiol. Scand., 133 (1988) 595-596.
18. [18] Grenhoff, J. and Svensson, T.H., Pharmacology of Nicotine, Br. J. Addict., 84 (1989) 477-492.
19. [19] Imperato, A., Mulas, A. and DiChiara, G., Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats, Eur. J. Pharmacol., 132 (1986) 337-338.
20. 1 receptor and is dependent on NMDA stimulation, Mol. Brain Res., 23 (1994) 1-13.
21. [21] Leikola-Pelho, T. and Jackson, D.M., Preferential stimulation of locomotor activity by ventral tegmental microinjections of (-)-nicotine, Pharmacol. Toxicol., 70 (1992) 50-52.
22. [22] Lichtensteiger, W., Hefti, F., Felix, D., Huwler, T., Melamed, E. and Schlumpf, M., Stimulation of nigrostriatal dopamine neurones by nicotine, Neuropharmacology, 21 (1982) 963-968.
23. [23] Liu J., Nickolenko J. and Sharp F.R., Morphine induces c-fos and junB in striatum and nucleus accumbens via D1 and N-methyl-D-aspartate receptors, Proc. Natl. Acad. Sci. USA, 91 (1994) 8537-8541.
24. [24] Matta, S.G., Foster, C.A. and Sharp, B.M., Nicotine stimulates the expression of cFos protein in the parvocellular paraventricular nucleus and brainstem catecholaminergic regions, Endocrinology, 132 (1993) 2149-2156.
25. [25] Mereu, G., Yoon, K.-W.P., Boi, V., Gessa, G.L., Naes, L. and Westfall, T.C., Preferential stimulation of ventral tegmental area dopaminergic neurons by nicotine, Eur. J. Pharmacol., 141 (1987) 395-399.
26. [26] Mifsud, J.-C., Hernandez, L. and Hoebel, B.G., Nicotine infused into the nucleus accumbens increases synaptic dopamine as measured by in vivo microdialysis, Brain Res., 478 (1989) 365-367.
27. [27] Moratalla R., Vickers E.A., Robertson H.A., Cochran B.H. and Graybiel A.M., Coordinate expression of c-fos and jun B is induced in the rat striatum by cocaine, J. Neurosci., 13 (1993) 423-133.
28. [28] Morgan, J.I. and Curran, T., Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. In W.M. Cowan, E.M. Shooter, C.F. Stevens and R.F. Thompson (Eds.), Annual Review of Neuroscience, Annual Reviews Inc., Palo Alto, California, USA, 1991, pp. 421-451.
29. [29] Morrison, C.F. and Stephenson, J.A., The occurrence of tolerance to a central depressant effect of nicotine, Br. J. Pharmacol., 46 (1972) 151-156.
30. [30] Museo, E. and Wise, R.Y., Sensitization of locomotion following repeated ventral tegmental injections of cytisine, Pharmacol. Biochem. Behav., 4 (1994) 521-524.
31. [31] Nisell, M., Nomikos, G.G., Hertel, P., Panagis, G. and Svensson, T.H., Condition-independent sensitization of locomotor stimulation and mesocortical dopamine release following chronic nicotine treatment in the rat, Synapse, 22 (1996) 369-381.
32. [32] Nisell, M., Nomikos, G.G. and Svensson, T.H., Systemic nicotine induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area, Synapse, 16 (1994) 36-44.
33. [33] Nisell, M., Nomikos, G.G. and Svensson, T.H., Nicotine dependence, midbrain dopamine systems and psychiatric disorders, Pharmacol. Toxicol., 76 (1995) 157-162.
34. [34] Pang, Y., Kiba, H. and Jayaraman, A., Acute nicotine injections induce c-fos mostly in non-dopaminergic neurons of the midbrain of the rat. Mol. Brain Res., 20 (1993) 162-170.
35. [35] Paxinos, G. and Watson, C., (1986) The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, Sydney.
36. [36] Persico, A.M., Schindler, C.W., O'Hara, B.F., Brannock, M.T. and Uhl, G.R., Brain transcription factor expression: effects of acute and chronic amphetamine and injection stress, Mol. Brain Res., 20 (1993) 91-100.
37. [37] Reavill, C. and Stolerman, I.P., Locomotor activity in rats after administration of nicotinic agonists intracerebrally, Br. J. Pharmacol., 99 (1990) 273-278.
38. [38] Ren, T. and Sagar, S.M., Induction of c-fos immunostaining in the rat brain after systemic administration of nicotine, Brain Res. Bull., 29 (1992) 589-597.
39. [39] Robertson, G.S. and Fibiger, H.C., Neuroleptics increase c-fos expression in the forebrain: contrasting effects of haloperidol and clozapine, Neuroscience, 46 (1992) 315-328.
40. 3H]dopamine release by nicotine in rat nucleus accumbens, J. Neurochem., 49 (1987) 1449-1454.
41. 3H]acetycholine on catecholamine and serotonin axons in brain, J. Neurochem., 42 (1984) 1495-1498.
42. [42] Stolerman, I.P., Fink, R. and Jarvik, M.E., Acute and chronic tolerance to nicotine measured by activity in rats, Psychopharmacologia, 30 (1973) 329-342.
43. [43] Svensson, T.H., Grenhoff, J. and Engberg, G., Effect of nicotine on dynamic function of brain catecholammergic neurons. In The Biology of Nicotine Dependence, Wiley, Chichester (Ciba Foundation Symposium 152), 1990, pp. 169-185.
44. [44] Vale, A.L. and Balfour, D.J.K., Aversive environmental stimuli as a factor in the psychostimulant response to nicotine, Pharmacol. Biochem. Behav., 32 (1989) 857-860.
45. [45] Wada, E., Wada, K., Boulter, J., Deneris, E., Heineman, S., Patrick, J. and Swanson, L.W., Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: a hybridization histochemical study in the rat, J. Comp. Neurol., 284 (1989) 314-335.
46. [46] Young S.T., Porrino L.J. and Iadarola M.J., Cocaine induces striatal c-Fos-immunoreactive proteins via dopaminergic D1 receptors, Proc. Natl. Acad. Sci. USA, 88 (1991) 1291-1295.