Glycine transporter isoforms in the mammalian central nervous system: Structures, functions and therapeutic promises

Current Opinion in Drug Discovery and Development

Volumn 6, Issue 5, 2003, Pages 675-682

  Gomeza, Jesus ^a   Ohno, Koji ^b   Betz, Heinrich ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c MAX PLANCK INSTITUTE FOR BRAIN RESEARCH   (Germany)

Author keywords

Glycine; Inhibitory glycine receptor; N methyl D aspartate receptor; Neurotransmitter uptake; Transport inhibitors

Indexed keywords

2 AMINO 4 PENTENOATE DERIVATIVE; 4 BENZYLOXY 3,5 DIMETHOXY N [(1 DIMETHYLAMINOCYCLOPENTYL)METHYL]BENZAMIDE; ALCOHOL; ALKANOL; ALX 5407; AMINO ACID; AMOXAPINE; ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; GLYCINE; GLYCINE RECEPTOR; GLYCINE RECEPTOR ANTAGONIST; ISOPROTEIN; KETAMINE; N [3 (4' FLUOROPHENYL) 3 (4' PHENYLPHENOXY)PROPYL]SARCOSINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N METHYL N [(4 TRIFLUOROMETHYL)PHENOXY] 3 PHENYLPROPYLGLYCINE; NEUROTRANSMITTER; NEUROTRANSMITTER RECEPTOR; ORG 24461; ORG 24598; PHENCYCLIDINE; POSTSYNAPTIC RECEPTOR; SARCOSINE; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG;

CENTRAL NERVOUS SYSTEM; CLINICAL TRIAL; DRUG TARGETING; GLIA CELL; HUMAN; MAMMAL; MENTAL DISEASE; NERVE CELL; NEUROLOGIC DISEASE; NEUROTRANSMITTER UPTAKE; NONHUMAN; PAIN; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; SCHIZOPHRENIA; SYNAPTIC INHIBITION;

AMINO ACID TRANSPORT SYSTEMS, NEUTRAL; ANIMALS; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM AGENTS; GLYCINE; GLYCINE PLASMA MEMBRANE TRANSPORT PROTEINS; MAMMALS; MEMBRANE PROTEINS; NERVOUS SYSTEM DISEASES; SYNAPTIC TRANSMISSION;

EID: 0142059881     PISSN: 13676733     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (74)

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