Involvement of cyclin-dependent pathway in the inhibitory effect of delphinidin on angiogenesis

Cardiovascular Research

Volumn 59, Issue 2, 2003, Pages 479-487

  Favot, Laure ^a   Martin, Sophie ^a   Keravis, Thérèse ^a   Andriantsitohaina, Ramaroson ^a   Lugnier, Claire ^a  

^a CNRS   (France)

Author keywords

Angiogenesis; Atherosclerosis; Endothelial function; Growth factors; Protein kinases

Indexed keywords

ANTHOCYANIN; CYCLIN A; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR; DELPHINIDIN; POLYPHENOL; PROTEIN P27; VASCULOTROPIN;

ANGIOGENESIS; ARTICLE; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL MIGRATION; CELL PROLIFERATION; CHORIOALLANTOIS; CLINICAL PATHWAY; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG POTENCY; ENDOTHELIUM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; INHIBITION KINETICS; NEOVASCULARIZATION (PATHOLOGY); PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; UMBILICUS; WESTERN BLOTTING;

ANGIOGENESIS INHIBITORS; ANTHOCYANINS; BLOTTING, WESTERN; CELL CYCLE; CELL MOVEMENT; CELLS, CULTURED; CYCLINS; DEPRESSION, CHEMICAL; ENDOTHELIUM, VASCULAR; HUMANS; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 0142026935     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(03)00433-4     Document Type: Article

References (45)

1. Bravo L. Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutr Rev. 56:1998;317-333.
2. Steinmetz K.A., Potter J.D. Vegetables, fruit, and cancer prevention: a review. J Am Diet Assoc. 96:1996;1027-1039.
3. Soleas G.J., Diamandis E.P., Goldberg D.M. Wine as a biological fluid: history, production, and role in disease prevention. J Clin Lab Anal. 11:1997;287-313.
4. Tosetti F., Ferrari N., De Flora S., Albini A. Angioprevention: angiogenesis is a common and key target for cancer chemopreventive agents. FASEB J. 16:2002;2-14.
5. Middleton E. Jr., Kandaswami C., Theoharides T.C. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacol Rev. 52:2000;673-751.
6. Jang M., Cai L., Udeani G.O., et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science. 275:1997;218-220.
7. Fotsis T., Pepper M.S., Aktas E., et al. Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis. Cancer Res. 57:1997;2916-2921.
8. Brakenhielm E., Cao R., Cao Y. Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes. FASEB J. 15:2001;1798-1800.
9. Cao Y., Cao R., Brakenhielm E. Antiangiogenic mechanisms of diet-derived polyphenols. J Nutr Biochem. 13:2002;380-390.
10. Griffioen A.W., Molema G. Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacol Rev. 52:2000;237-268.
11. Pepper M.S. Manipulating angiogenesis. From basic science to the bedside. Arterioscler Thromb Vasc Biol. 17:1997;605-619.
12. Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med. 1:1995;27-31.
13. Wang H., Cao G., Prior R.L. Oxygen radical absorbing capacity of anthocyanins. J Agric Food Chem. 45:1997;304-309.
14. Bernatova I., Pechanova O., Babal P., et al. Wine polyphenols improve cardiovascular remodeling and vascular function in NO-deficient hypertension. Am J Physiol Heart Circ Physiol. 282:2002;H942-H948.
15. Andriambeloson E., Magnier C., Haan-Archipoff G., et al. Natural dietary polyphenolic compounds cause endothelium-dependent vasorelaxation in rat thoracic aorta. J Nutr. 128:1998;2324-2333.
16. Jackson J.R., Seed M.P., Kircher C.H., Willoughby D.A., Winkler J.D. The codependence of angiogenesis and chronic inflammation. FASEB J. 11:1997;457-465.
17. Klein-Soyer C., Beretz A., Millon-Collard R., Abecassis J., Cazenave J.P. A simple in vitro model of mechanical injury of confluent cultured endothelial cells to study quantitatively the repair process. Thromb Haemost. 56:1986;232-235.
18. Scherberich A., Campos-Toimil M., Rondé P., Takeda K., Beretz A. Migration of human vascular smooth muscle cells involves serum-dependent repeated cytosolic calcium transients. J Cell Sci. 4:2000;653-662.
19. Cory A.H., Owen T.C., Barltrop J.A., Cory J.G. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun. 3:1991;207-212.
20. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the folin phenol reagent. J Biol Chem. 193:1951;265-275.
21. Lugnier C., Keravis T., Le Bec A., et al. Characterization of cyclic nucleotide phosphodiesterase isoforms associated to isolated cardiac nuclei. Biochim Biophys Acta. 1472:1999;431-446.
22. Auerbach R., Kubai L., Knighton D., Folkman J. A simple procedure for the long-term cultivation of chicken embryos. Dev Biol. 41:1974;391-394.
23. Martin S., Andriambeloson E., Takeda K., Andriantsitohaina R. Red wine polyphenols increase calcium in bovine aortic endothelial cells: a basis to elucidate signalling pathways leading to nitric oxide production. Br J Pharmacol. 135:2002;1579-1587.
24. Goukassian D., Diez-Juan A., Asahara T., et al. Overexpression of p27(Kip1) by doxycycline-regulated adenoviral vectors inhibits endothelial cell proliferation and migration and impairs angiogenesis. FASEB J. 15:2001;1877-1885.
25. Sun J., Marx S.O., Chen H.J., et al. Role for p27(Kip1) in vascular smooth muscle cell migration. Circulation. 103:2001;2967-2972.
26. Chen D., Walsh K., Wang J. Regulation of cdk2 activity in endothelial cells that are inhibited from growth by cell contact. Arterioscler Thromb Vasc Biol. 20:2000;629-635.
27. Ahmad N., Adhami V.M., Afaq F., Feyes D.K., Mukhtar H. Resveratrol causes WAF-1/p21-mediated G(1)-phase arrest of cell cycle and induction of apoptosis in human epidermoid carcinoma A431 cells. Clin Cancer Res. 7:2001;1466-1473.
28. Alcocer F., Whitley D., Salazar-Gonzalez J.F., et al. Quercetin inhibits human vascular smooth muscle cell proliferation and migration. Surgery. 131:2002;198-204.
29. Sherr C.J. G1 phase progression: cycling on cue. Cell. 79:1994;551-555.
30. Jacks T., Weinberg R.A. Cell-cycle control and its watchman. Nature. 381:1996;643-644.
31. Sherr C.J., Roberts J.M. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9:1995;1149-1163.
32. Ii M., Hoshiga M., Fukui R., et al. Beraprost sodium regulates cell cycle in vascular smooth muscle cells through cAMP signaling by preventing down-regulation of p27(Kip1). Cardiovasc Res. 52:2001;500-508.
33. Dimberg A., Bahram F., Karlberg I., et al. Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27(Kip1). Blood. 99:2002;2199-2206.
34. Lavoie J.N., L'Allemain G., Brunet A., Muller R., Pouyssegur J. Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J Biol Chem. 271:1996;20608-20616.
35. Obaya A.J., Sedivy J.M. Regulation of cyclin-Cdk activity in mammalian cells. Cell Mol Life Sci. 59:2002;126-142.
36. Ishimi Y., Komamura-Kohno Y., You Z., Omori A., Kitagawa M. Inhibition of Mcm4,6,7 helicase activity by phosphorylation with cyclin A/Cdk2. J Biol Chem. 275:2000;16235-16241.
37. Cardoso M.C., Leonhardt H., Nadal-Ginard B. Reversal of terminal differentiation and control of D.N.A. replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication. Cell. 74:1993;979-992.
38. Noda Y., Kaneyuki T., Mori A., Packer L. Antioxidant activities of pomegranate fruit extract and its anthocyanidins: delphinidin, cyanidin, and pelargonidin. J Agric Food Chem. 50:2002;166-171.
39. Cai H., Li Z., Davis M.E., et al. Akt-dependent phosphorylation of serine 1179 and mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2 cooperatively mediate activation of the endothelial nitric-oxide synthase by hydrogen peroxide. Mol Pharmacol. 63:2003;325-331.
40. Nico B., De Giorgis M., Roncali L., Ribatti D. Vascular endothelial growth factor and vascular endothelial growth factor receptor-2 expression in the chick embryo area vasculosa. Histochem J. 33:2001;283-286.
41. Ribatti D., Cruz A., Nico B., et al. In situ hybridization and immunogold localization of vascular endothelial growth factor receptor-2 on the pericytes of the chick choriallantoic membrane. Cytokine. 17:2002;262-265.
42. Kuhnau J. The flavonoids. A class of semi-essential food components: their role in human nutrition. World Rev Nutr Diet. 24:1976;117-191.
43. Matsumoto H., Inaba H., Kishi M., et al. Orally administered delphinidin 3-rutinoside and cyanidin 3-rutinoside are directly absorbed in rats and humans and appear in the blood as the intact forms. J Agric Food Chem. 49:2001;1546-1551.
44. Nyman N.A., Kumpulainen J.T. Determination of anthocyanidins in berries and red wine by high-performance liquid chromatography. J Agric Food Chem. 49:2001;4183-4187.
45. Meiers S., Kemeny M., Weyand U., et al. The anthocyanidins cyanidin and delphinidin are potent inhibitors of the epidermal growth-factor receptor. J Agric Food Chem. 49:2001;958-962.