메뉴 건너뛰기




Volumn 14, Issue 1, 2003, Pages 18-25

Ornal chemotherapy in colorectal cancer treatment: Review of the literature

Author keywords

Colorectal cancer; Oral chemotherapy; Treatment

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR; 5 ETHYNYLURACIL; 9 AMINO 20 CAMPTOTHECIN; 9 AMINOCAMPTOTHECIN; 9 NITRO 20 CAMPTOTHECIN; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CAMPTOTHECIN DERIVATIVE; CAPECITABINE; CARMOFUR; DOXOFLURIDINE; FLOXURIDINE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; LEVAMISOLE; MITOMYCIN C; MMI 166; OXALIPLATIN; PLEVITREXED; PYRIMIDINE DERIVATIVE; RALTITREXED; RUBITECAN; TEGAFUR; UFT; UNCLASSIFIED DRUG; URACIL;

EID: 0037303731     PISSN: 09536205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0953-6205(02)00213-3     Document Type: Review
Times cited : (14)

References (64)
  • 1
    • 0033616484 scopus 로고    scopus 로고
    • Colorectal cancer
    • Midgley R., Kerr D. Colorectal cancer. Lancet. 353:1999;391-399.
    • (1999) Lancet , vol.353 , pp. 391-399
    • Midgley, R.1    Kerr, D.2
  • 2
    • 0034994538 scopus 로고    scopus 로고
    • Conventional cytotoxic and novel therapeutic concepts in colorectal cancer
    • Midgley R., Kerr D. Conventional cytotoxic and novel therapeutic concepts in colorectal cancer. Exp Opin Invest Drugs. 10:2001;1011-1019.
    • (2001) Exp Opin Invest Drugs , vol.10 , pp. 1011-1019
    • Midgley, R.1    Kerr, D.2
  • 3
    • 0034791938 scopus 로고    scopus 로고
    • Answering patients' needs: Oral alternatives to intravenous therapy
    • Borner M., Scheithauer W., Twelves C., Maroun J., Wilke H. Answering patients' needs: oral alternatives to intravenous therapy. Oncologist. 6:(Suppl 4):2001;12-16.
    • (2001) Oncologist , vol.6 , Issue.SUPPL. 4 , pp. 12-16
    • Borner, M.1    Scheithauer, W.2    Twelves, C.3    Maroun, J.4    Wilke, H.5
  • 4
    • 0031017851 scopus 로고    scopus 로고
    • Patient preferences for oral versus intravenous palliative chemotherapy
    • Liu G., Franssen E., Fitch M.I., Warner E. Patient preferences for oral versus intravenous palliative chemotherapy. J Clin Oncol. 15:1997;110-115.
    • (1997) J Clin Oncol , vol.15 , pp. 110-115
    • Liu, G.1    Franssen, E.2    Fitch, M.I.3    Warner, E.4
  • 5
    • 0035503436 scopus 로고    scopus 로고
    • Oral versus intravenous fluoropyrimidines for advanced colorectal cancer: By either route it's all the same
    • Mayer R.J. Oral versus intravenous fluoropyrimidines for advanced colorectal cancer: by either route it's all the same. J Clin Oncol. 19:2001;4093-4096.
    • (2001) J Clin Oncol , vol.19 , pp. 4093-4096
    • Mayer, R.J.1
  • 6
    • 0032822048 scopus 로고    scopus 로고
    • New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: Requirement of six genes for cytidine metabolism
    • Kurtz J.E., Exinger F., Erbs P., Jund R. New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism. Curr Genet. 36:1999;130-136.
    • (1999) Curr Genet , vol.36 , pp. 130-136
    • Kurtz, J.E.1    Exinger, F.2    Erbs, P.3    Jund, R.4
  • 7
    • 0029127078 scopus 로고
    • Doxifluridine: An active agent in advanced gastrointestinal cancer
    • Di Bartolomeo M., Bajetta E., Somma L., Buzzoni R. Doxifluridine: an active agent in advanced gastrointestinal cancer. Tumori. 81:(Suppl 3):1995;147-150.
    • (1995) Tumori , vol.81 , Issue.SUPPL. 3 , pp. 147-150
    • Di Bartolomeo, M.1    Bajetta, E.2    Somma, L.3    Buzzoni, R.4
  • 8
    • 0029092369 scopus 로고
    • Doxifluridine and leucovorin: An oral treatment combination in advanced colorectal cancer
    • Bajetta E., Colleoni M., Di Bartolomeo M., et al. Doxifluridine and leucovorin: an oral treatment combination in advanced colorectal cancer. J Clin Oncol. 13:1995;2613-2619.
    • (1995) J Clin Oncol , vol.13 , pp. 2613-2619
    • Bajetta, E.1    Colleoni, M.2    Di Bartolomeo, M.3
  • 9
    • 0031658910 scopus 로고    scopus 로고
    • Results of leucovorin and doxifluridine oral regimen in the treatment of metastatic colorectal cancer
    • Neri B., Gemelli M.T., Pantalone D., et al. Results of leucovorin and doxifluridine oral regimen in the treatment of metastatic colorectal cancer. Anticancer Drugs. 9:1998;599-602.
    • (1998) Anticancer Drugs , vol.9 , pp. 599-602
    • Neri, B.1    Gemelli, M.T.2    Pantalone, D.3
  • 10
    • 0035371029 scopus 로고    scopus 로고
    • Preoperative chemoradiotherapy with oral doxifluridine plus low-dose oral leucovorin in unresectable primary rectal cancer
    • Seong J., Cho J.H., Kim N.K., Min J.S., Suh C.O. Preoperative chemoradiotherapy with oral doxifluridine plus low-dose oral leucovorin in unresectable primary rectal cancer. Int J Radiat Oncol Biol Phys. 50:2001;435-439.
    • (2001) Int J Radiat Oncol Biol Phys , vol.50 , pp. 435-439
    • Seong, J.1    Cho, J.H.2    Kim, N.K.3    Min, J.S.4    Suh, C.O.5
  • 11
    • 0031859855 scopus 로고    scopus 로고
    • Preliminary studies of a novel oral fluoropyrimidine carbamate: Capecitabine
    • Budman D.R., Meropol N.J., Reigner B., et al. Preliminary studies of a novel oral fluoropyrimidine carbamate: capecitabine. J Clin Oncol. 16:1998;1795-1802.
    • (1998) J Clin Oncol , vol.16 , pp. 1795-1802
    • Budman, D.R.1    Meropol, N.J.2    Reigner, B.3
  • 12
    • 0034016343 scopus 로고    scopus 로고
    • Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: Results of a randomized phase II study
    • Van Cutsem E., Findlay M., Osterwalder B., et al. Capecitabine, an oral fluoropyrimidine carbamate with substantial activity in advanced colorectal cancer: results of a randomized phase II study. J Clin Oncol. 18:2000;1337-1345.
    • (2000) J Clin Oncol , vol.18 , pp. 1337-1345
    • Van Cutsem, E.1    Findlay, M.2    Osterwalder, B.3
  • 13
    • 0035871538 scopus 로고    scopus 로고
    • Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: Results of a randomized phase III study
    • Hoff P.M., Ansari R., Batist G., et al. Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study. J Clin Oncol. 19:2001;2282-2292.
    • (2001) J Clin Oncol , vol.19 , pp. 2282-2292
    • Hoff, P.M.1    Ansari, R.2    Batist, G.3
  • 14
    • 0035503151 scopus 로고    scopus 로고
    • Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: Results of a large phase III study
    • Van Cutsem E., Twelves C., Cassidy J., et al. Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study. J Clin Oncol. 19:2001;4097-4106.
    • (2001) J Clin Oncol , vol.19 , pp. 4097-4106
    • Van Cutsem, E.1    Twelves, C.2    Cassidy, J.3
  • 15
    • 0034745284 scopus 로고    scopus 로고
    • Capecitabine (Xeloda) improves medical resource use compared with 5-fluorouracil plus leucovorin in a phase III trial conducted in patients with advanced colorectal carcinoma
    • Twelves C., Boyer M., Findlay M., et al. Capecitabine (Xeloda) improves medical resource use compared with 5-fluorouracil plus leucovorin in a phase III trial conducted in patients with advanced colorectal carcinoma. Eur J Cancer. 37:2001;597-604.
    • (2001) Eur J Cancer , vol.37 , pp. 597-604
    • Twelves, C.1    Boyer, M.2    Findlay, M.3
  • 16
    • 0035292311 scopus 로고    scopus 로고
    • Future directions in adjuvant therapy for stage III colon carcinoma
    • Pitot H.C., Goldberg R.M. Future directions in adjuvant therapy for stage III colon carcinoma. Oncology (Huntingt). 15:(Suppl 5):2001;31-36.
    • (2001) Oncology (Huntingt) , vol.15 , Issue.SUPPL. 5 , pp. 31-36
    • Pitot, H.C.1    Goldberg, R.M.2
  • 17
    • 0000301005 scopus 로고    scopus 로고
    • Phase II study of capecitabine (CAP)+oxaliplatin (OXA) in first line and second line treatment of advanced or metastatic colorectal cancer (ACC)
    • Borner M.M., Mueller S., Roth A., et al. Phase II study of capecitabine (CAP)+oxaliplatin (OXA) in first line and second line treatment of advanced or metastatic colorectal cancer (ACC). Proc Am Soc Clin Oncol. 20:2001;137a.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Borner, M.M.1    Mueller, S.2    Roth, A.3
  • 18
    • 0003209464 scopus 로고    scopus 로고
    • Oxaliplatin and capecitabine in advanced colorectal cancer: A dose finding trial
    • DeSantis S., Zeuli M., Di Costanzo A., et al. Oxaliplatin and capecitabine in advanced colorectal cancer: a dose finding trial. Proc Am Soc Clin Oncol. 20:2001;141a.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • DeSantis, S.1    Zeuli, M.2    Di Costanzo, A.3
  • 19
    • 0003199012 scopus 로고    scopus 로고
    • Extended phase I study of capecitabine in combination with a weekly schedule of irinotecan as first-line chemotherapy in metastatic colorectal cancer
    • Schleucher N., Tewes M., Achterrath W., et al. Extended phase I study of capecitabine in combination with a weekly schedule of irinotecan as first-line chemotherapy in metastatic colorectal cancer. Proc Am Soc Clin Oncol. 20:2001;141a.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Schleucher, N.1    Tewes, M.2    Achterrath, W.3
  • 20
    • 0029993886 scopus 로고    scopus 로고
    • Oral adjuvant chemotherapy with carmofur (HCFU) for colorectal cancer: 5-year follow-up. Tokai HCFU Study Group - Third study on colorectal cancer
    • Ito K., Yamaguchi A., Miura K., et al. Oral adjuvant chemotherapy with carmofur (HCFU) for colorectal cancer: 5-year follow-up. Tokai HCFU Study Group - third study on colorectal cancer. J Surg Oncol. 63:1996;107-111.
    • (1996) J Surg Oncol , vol.63 , pp. 107-111
    • Ito, K.1    Yamaguchi, A.2    Miura, K.3
  • 21
    • 0035430485 scopus 로고    scopus 로고
    • Optimal duration of oral adjuvant chemotherapy with Carmofur in colorectal cancer patients: The Kansai Carmofur Study Group trial III
    • Nakamura T., Ohno M., Tabuchi Y., et al. Optimal duration of oral adjuvant chemotherapy with Carmofur in colorectal cancer patients: the Kansai Carmofur Study Group trial III. Int J Oncol. 19:2001;291-298.
    • (2001) Int J Oncol , vol.19 , pp. 291-298
    • Nakamura, T.1    Ohno, M.2    Tabuchi, Y.3
  • 22
    • 0035349921 scopus 로고    scopus 로고
    • An individual patient data meta-analysis of long supported adjuvant chemotherapy with oral carmofur in patients with curatively resected colorectal cancer
    • Sakamoto J., Kodaira S., Hamada C., et al. An individual patient data meta-analysis of long supported adjuvant chemotherapy with oral carmofur in patients with curatively resected colorectal cancer. Oncol Rep. 8:2001;697-703.
    • (2001) Oncol Rep , vol.8 , pp. 697-703
    • Sakamoto, J.1    Kodaira, S.2    Hamada, C.3
  • 23
    • 0034860293 scopus 로고    scopus 로고
    • A phase I study of raltitrexed (tomudex) combined with carmofur in metastatic colorectal cancer
    • Osterlund P., Elomaa I., Virkkunen P., Joensuu H. A phase I study of raltitrexed (tomudex) combined with carmofur in metastatic colorectal cancer. Oncology. 61:2001;113-119.
    • (2001) Oncology , vol.61 , pp. 113-119
    • Osterlund, P.1    Elomaa, I.2    Virkkunen, P.3    Joensuu, H.4
  • 24
    • 0031060360 scopus 로고    scopus 로고
    • Clinical application of biochemical modulation in cancer chemotherapy: Biochemical modulation for 5-FU
    • Taguchi T. Clinical application of biochemical modulation in cancer chemotherapy: biochemical modulation for 5-FU. Oncology. 54:(Suppl 1):1997;12-18.
    • (1997) Oncology , vol.54 , Issue.SUPPL. 1 , pp. 12-18
    • Taguchi, T.1
  • 25
    • 0031750330 scopus 로고    scopus 로고
    • UFT plus oral Leucovorin: A new oral treatment for colorectal cancer
    • Hoff P.M., Pazdur R. UFT plus oral Leucovorin: a new oral treatment for colorectal cancer. Oncologist. 3:1998;155-164.
    • (1998) Oncologist , vol.3 , pp. 155-164
    • Hoff, P.M.1    Pazdur, R.2
  • 26
    • 0029966745 scopus 로고    scopus 로고
    • Phase I trials of uracil-tegafur (UFT) using 5- and 28-day administration schedules: Demonstration of schedule-dependent toxicities
    • Pazdur R., Lassere Y., Diaz-Canton E., Bready B., Ho D.H. Phase I trials of uracil-tegafur (UFT) using 5- and 28-day administration schedules: demonstration of schedule-dependent toxicities. Anticancer Drugs. 7:1996;728-733.
    • (1996) Anticancer Drugs , vol.7 , pp. 728-733
    • Pazdur, R.1    Lassere, Y.2    Diaz-Canton, E.3    Bready, B.4    Ho, D.H.5
  • 27
    • 0028099423 scopus 로고
    • Phase II trial of uracil and tegafur plus oral leucovorin: An effective oral regimen in the treatment of metastatic colorectal carcinoma
    • Pazdur R., Lassere Y., Rhodes V., et al. Phase II trial of uracil and tegafur plus oral leucovorin: an effective oral regimen in the treatment of metastatic colorectal carcinoma. J Clin Oncol. 12:1994;2296-2300.
    • (1994) J Clin Oncol , vol.12 , pp. 2296-2300
    • Pazdur, R.1    Lassere, Y.2    Rhodes, V.3
  • 28
    • 0028820944 scopus 로고
    • A fixed-ratio combination of uracil and Ftorafur (UFT) with low dose leucovorin. An active oral regimen for advanced colorectal cancer
    • Saltz L.B., Leichman C.G., Young C.W., et al. A fixed-ratio combination of uracil and Ftorafur (UFT) with low dose leucovorin. An active oral regimen for advanced colorectal cancer. Cancer. 75:1995;782-785.
    • (1995) Cancer , vol.75 , pp. 782-785
    • Saltz, L.B.1    Leichman, C.G.2    Young, C.W.3
  • 29
    • 0029563823 scopus 로고
    • Efficacy of oral tegafur modulation by uracil and leucovorin in advanced colorectal cancer. A phase II study
    • Gonzalez-Baron M., Feliu J., de la Gandara I., et al. Efficacy of oral tegafur modulation by uracil and leucovorin in advanced colorectal cancer. A phase II study. Eur J Cancer. 31A:1995;2215-2219.
    • (1995) Eur J Cancer , vol.31 A , pp. 2215-2219
    • Gonzalez-Baron, M.1    Feliu, J.2    De la Gandara, I.3
  • 30
    • 0031060206 scopus 로고    scopus 로고
    • Phase II study of UFT plus leucovorin in colorectal cancer
    • Pazdur R. Phase II study of UFT plus leucovorin in colorectal cancer. Oncology. 54:(Suppl 1):1997;19-23.
    • (1997) Oncology , vol.54 , Issue.SUPPL. 1 , pp. 19-23
    • Pazdur, R.1
  • 31
    • 0032870981 scopus 로고    scopus 로고
    • Novel agents for colorectal cancer
    • Pazdur R., Royce M.E. Novel agents for colorectal cancer. Exp Opin Invest Drugs. 8:1999;1639-1652.
    • (1999) Exp Opin Invest Drugs , vol.8 , pp. 1639-1652
    • Pazdur, R.1    Royce, M.E.2
  • 32
    • 0001073793 scopus 로고    scopus 로고
    • Randomized comparative study of ORZEL (oral uracil/tegafur (UFT) plus leucovorin (LV)) versus parenteral 5-fluorouracil (5-FU) plus LV in patients with metastatic colorectal cancer
    • Carmichael J., Popiela T., Radstone D. Randomized comparative study of ORZEL (oral uracil/tegafur (UFT) plus leucovorin (LV)) versus parenteral 5-fluorouracil (5-FU) plus LV in patients with metastatic colorectal cancer. Proc Am Soc Clin Oncol. 18:1999;264a.
    • (1999) Proc Am Soc Clin Oncol , vol.18
    • Carmichael, J.1    Popiela, T.2    Radstone, D.3
  • 33
    • 24044470367 scopus 로고    scopus 로고
    • UFT in the treatment of colorectal and breast cancer
    • Sun W., Haller D. UFT in the treatment of colorectal and breast cancer. Oncology (Huntingt). 15:(Suppl 2):2001;49-56.
    • (2001) Oncology (Huntingt) , vol.15 , Issue.SUPPL. 2 , pp. 49-56
    • Sun, W.1    Haller, D.2
  • 34
    • 0036731818 scopus 로고    scopus 로고
    • Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Douillard J.-Y., Hoff P.M., Skillings J.R., et al. Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol. 20:(17):2002;3605-3616.
    • (2002) J Clin Oncol , vol.20 , Issue.17 , pp. 3605-3616
    • Douillard, J.-Y.1    Hoff, P.M.2    Skillings, J.R.3
  • 35
    • 0036727089 scopus 로고    scopus 로고
    • Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Carmichael J., Popiela T., Radstone D., et al. Randomized comparative study of tegafur/uracil and oral leucovorin versus parenteral fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol. 20:(17):2002;3617-3627.
    • (2002) J Clin Oncol , vol.20 , Issue.17 , pp. 3617-3627
    • Carmichael, J.1    Popiela, T.2    Radstone, D.3
  • 36
    • 0035204403 scopus 로고    scopus 로고
    • Phase I trial of weekly irinotecan combined with UFT as second-line treatment for advanced colorectal cancer
    • Alonso V., Escudero P., Zorrilla M., et al. Phase I trial of weekly irinotecan combined with UFT as second-line treatment for advanced colorectal cancer. Eur J Cancer. 37:2001;2385-2391.
    • (2001) Eur J Cancer , vol.37 , pp. 2385-2391
    • Alonso, V.1    Escudero, P.2    Zorrilla, M.3
  • 37
    • 0034304152 scopus 로고    scopus 로고
    • UFT/leucovorin plus irinotecan in advanced or metastatic colorectal cancer
    • Price T., Hill M. UFT/leucovorin plus irinotecan in advanced or metastatic colorectal cancer. Oncology (Huntingt). 14:(Suppl 9):2000;28-31.
    • (2000) Oncology (Huntingt) , vol.14 , Issue.SUPPL. 9 , pp. 28-31
    • Price, T.1    Hill, M.2
  • 38
    • 0032784111 scopus 로고    scopus 로고
    • Eniluracil treatment completely inactivates dihydropyrimidine dehydrogenase in colorectal tumors
    • Ahmed F.Y., Johnston S.J., Cassidy J., et al. Eniluracil treatment completely inactivates dihydropyrimidine dehydrogenase in colorectal tumors. J Clin Oncol. 17:1999;2439-2445.
    • (1999) J Clin Oncol , vol.17 , pp. 2439-2445
    • Ahmed, F.Y.1    Johnston, S.J.2    Cassidy, J.3
  • 39
    • 0033946583 scopus 로고    scopus 로고
    • Eniluracil: An irreversible inhibitor of dihydropyrimidine dehydrogenase
    • Schilsky R.L., Kindler H.L. Eniluracil: an irreversible inhibitor of dihydropyrimidine dehydrogenase. Exp Opin Invest Drugs. 9:2000;1635-1649.
    • (2000) Exp Opin Invest Drugs , vol.9 , pp. 1635-1649
    • Schilsky, R.L.1    Kindler, H.L.2
  • 40
    • 0035228027 scopus 로고    scopus 로고
    • Oral eniluracil/5-FU for advanced colon and breast carcinomas
    • Benson A.B. 3rd. Oral eniluracil/5-FU for advanced colon and breast carcinomas. Oncology (Huntingt). 15:(Suppl 2):2001;57-63.
    • (2001) Oncology (Huntingt) , vol.15 , Issue.SUPPL. 2 , pp. 57-63
    • Benson A.B. III1
  • 41
    • 0034034108 scopus 로고    scopus 로고
    • A multicenter phase II study of a five-day regimen of oral 5-fluorouracil plus eniluracil with or without leucovorin in patients with metastatic colorectal cancer
    • Schilsky R.L., Bukowski R., Burris H. 3rd, et al. A multicenter phase II study of a five-day regimen of oral 5-fluorouracil plus eniluracil with or without leucovorin in patients with metastatic colorectal cancer. Ann Oncol. 11:2000;415-420.
    • (2000) Ann Oncol , vol.11 , pp. 415-420
    • Schilsky, R.L.1    Bukowski, R.2    Burris H. III3
  • 42
    • 0035312175 scopus 로고    scopus 로고
    • Phase II study of oral eniluracil, 5-fluorouracil, and leucovorin in patients with advanced colorectal carcinoma
    • Meropol N.J., Niedzwiecki D., Hollis D., Schilsky R.L., Mayer R.J. Phase II study of oral eniluracil, 5-fluorouracil, and leucovorin in patients with advanced colorectal carcinoma. Cancer. 91:2001;1256-1263.
    • (2001) Cancer , vol.91 , pp. 1256-1263
    • Meropol, N.J.1    Niedzwiecki, D.2    Hollis, D.3    Schilsky, R.L.4    Mayer, R.J.5
  • 43
    • 0033852502 scopus 로고    scopus 로고
    • Multicenter phase II study to evaluate a 28-day regimen of oral fluorouracil plus eniluracil in the treatment of patients with previously untreated metastatic colorectal cancer
    • Mani S., Hochster H., Beck T., et al. Multicenter phase II study to evaluate a 28-day regimen of oral fluorouracil plus eniluracil in the treatment of patients with previously untreated metastatic colorectal cancer. J Clin Oncol. 18:2000;2894-2901.
    • (2000) J Clin Oncol , vol.18 , pp. 2894-2901
    • Mani, S.1    Hochster, H.2    Beck, T.3
  • 44
    • 0003300519 scopus 로고    scopus 로고
    • North American phase III study of oral eniluracil (EU) plus oral-5-fluorouracil (5-FU) versus intravenous (IV) 5-FU plus leucovorin (LV) in the treatment of advanced colorectal cancer (ACC)
    • Levin J., Schilsky R.L., Burris H., et al. North American phase III study of oral eniluracil (EU) plus oral-5-fluorouracil (5-FU) versus intravenous (IV) 5-FU plus leucovorin (LV) in the treatment of advanced colorectal cancer (ACC). Proc Am Soc Clin Oncol. 20:2001;132a.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Levin, J.1    Schilsky, R.L.2    Burris, H.3
  • 45
    • 0037087668 scopus 로고    scopus 로고
    • Randomized, open-label, phase III study of a 28-day oral regimen of eniluracil plus fluorouracil versus intravenous fluorouracil plus leucovorin as first-line therapy in patients with metastatic/advanced colorectal cancer
    • Schilsky R.L., Levin J., West W.H., et al. Randomized, open-label, phase III study of a 28-day oral regimen of eniluracil plus fluorouracil versus intravenous fluorouracil plus leucovorin as first-line therapy in patients with metastatic/advanced colorectal cancer. J Clin Oncol. 20:(6):2002;1519-1526.
    • (2002) J Clin Oncol , vol.20 , Issue.6 , pp. 1519-1526
    • Schilsky, R.L.1    Levin, J.2    West, W.H.3
  • 46
    • 0003300519 scopus 로고    scopus 로고
    • International phase III study of oral eniluracil (EU) plus 5-fluorouracil (5-FU) versus intravenous (IV) 5-fu plus leucovorin (LV) in the treatment of advanced colorectal cancer (ACC)
    • Van Cutsem E., Sorensen J., Cassidy J., et al. International phase III study of oral eniluracil (EU) plus 5-fluorouracil (5-FU) versus intravenous (IV) 5-fu plus leucovorin (LV) in the treatment of advanced colorectal cancer (ACC). Proc Am Soc Clin Oncol. 20:2001;131a.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Van Cutsem, E.1    Sorensen, J.2    Cassidy, J.3
  • 47
    • 0035380385 scopus 로고    scopus 로고
    • New oral anticancer drug, TS-1 (S-1) - From bench to clinic
    • Shirasaka T., Tsukuda M., Inuyama Y., Taguchi T. [New oral anticancer drug, TS-1 (S-1) - from bench to clinic]. Gan To Kagaku Ryoho. 28:(S-1):2001;855-864.
    • (2001) Gan To Kagaku Ryoho , vol.28 , Issue.S-1 , pp. 855-864
    • Shirasaka, T.1    Tsukuda, M.2    Inuyama, Y.3    Taguchi, T.4
  • 48
    • 0032819756 scopus 로고    scopus 로고
    • An early phase II study of oral S-1, a newly developed 5-fluorouracil derivative for advanced and recurrent gastrointestinal cancers. The S-1 Gastrointestinal Cancer Study Group
    • Sugimachi K., Maehara Y., Horikoshi N., et al. An early phase II study of oral S-1, a newly developed 5-fluorouracil derivative for advanced and recurrent gastrointestinal cancers. The S-1 Gastrointestinal Cancer Study Group. Oncology. 57:1999;202-210.
    • (1999) Oncology , vol.57 , pp. 202-210
    • Sugimachi, K.1    Maehara, Y.2    Horikoshi, N.3
  • 49
    • 0034089123 scopus 로고    scopus 로고
    • Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group
    • Ohtsu A., Baba H., Sakata Y., et al. Phase II study of S-1, a novel oral fluoropyrimidine derivative, in patients with metastatic colorectal carcinoma. S-1 Cooperative Colorectal Carcinoma Study Group. Br J Cancer. 83:2000;141-145.
    • (2000) Br J Cancer , vol.83 , pp. 141-145
    • Ohtsu, A.1    Baba, H.2    Sakata, Y.3
  • 50
    • 0031795669 scopus 로고    scopus 로고
    • Alternative dosing schedules for irinotecan
    • Rothenberg M.L., Kuhn J.G., Schaaf L.J., et al. Alternative dosing schedules for irinotecan. Oncology (Huntingt). 12:(Suppl 6):1998;68-71.
    • (1998) Oncology (Huntingt) , vol.12 , Issue.SUPPL. 6 , pp. 68-71
    • Rothenberg, M.L.1    Kuhn, J.G.2    Schaaf, L.J.3
  • 51
    • 0033053185 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic trial of oral irinotecan administered daily for 5 days every 3 weeks in patients with solid tumors
    • Drengler R.L., Kuhn J.G., Schaaf L.J., et al. Phase I and pharmacokinetic trial of oral irinotecan administered daily for 5 days every 3 weeks in patients with solid tumors. J Clin Oncol. 17:1999;685-696.
    • (1999) J Clin Oncol , vol.17 , pp. 685-696
    • Drengler, R.L.1    Kuhn, J.G.2    Schaaf, L.J.3
  • 52
    • 0033034388 scopus 로고    scopus 로고
    • Phase I and pharmacologic study of oral (PEG-1000) 9-aminocamptothecin in adult patients with solid tumors
    • De Jonge M.J., Punt C.J., Gelderblom A.H., et al. Phase I and pharmacologic study of oral (PEG-1000) 9-aminocamptothecin in adult patients with solid tumors. J Clin Oncol. 17:1999;2219-2226.
    • (1999) J Clin Oncol , vol.17 , pp. 2219-2226
    • De Jonge, M.J.1    Punt, C.J.2    Gelderblom, A.H.3
  • 53
    • 0036134605 scopus 로고    scopus 로고
    • Preclinical evaluation of the anticancer activity and toxicity of 9-nitro-20(S)-camptothecin (Rubitecan)
    • Giovanella B.C., Stehlin J.S., Hinz H.R., Kozielski A.J., Harris N.J., Vardeman D.M. Preclinical evaluation of the anticancer activity and toxicity of 9-nitro-20(S)-camptothecin (Rubitecan). Int J Oncol. 20:2002;81-88.
    • (2002) Int J Oncol , vol.20 , pp. 81-88
    • Giovanella, B.C.1    Stehlin, J.S.2    Hinz, H.R.3    Kozielski, A.J.4    Harris, N.J.5    Vardeman, D.M.6
  • 54
    • 0034754334 scopus 로고    scopus 로고
    • A phase II study of 9-nitrocamptothecin in patients with advanced pancreatic adenocarcinoma
    • Konstadoulakis M.M., Antonakis P.T., Tsibloulis B.G., et al. A phase II study of 9-nitrocamptothecin in patients with advanced pancreatic adenocarcinoma. Cancer Chemother Pharmacol. 48:2001;417-420.
    • (2001) Cancer Chemother Pharmacol , vol.48 , pp. 417-420
    • Konstadoulakis, M.M.1    Antonakis, P.T.2    Tsibloulis, B.G.3
  • 56
    • 0037049884 scopus 로고    scopus 로고
    • Prevention of liver metastasis of human colon cancer by selective matrix metalloproteinase inhibitor MMI-166
    • Oba K., Konno H., Tanaka T., et al. Prevention of liver metastasis of human colon cancer by selective matrix metalloproteinase inhibitor MMI-166. Cancer Lett. 175:2002;45-51.
    • (2002) Cancer Lett , vol.175 , pp. 45-51
    • Oba, K.1    Konno, H.2    Tanaka, T.3
  • 57
    • 0034929463 scopus 로고    scopus 로고
    • Effect of combination therapy with matrix metalloproteinase inhibitor MMI-166 and mitomycin C on the growth and liver metastasis of human colon cancer
    • Ohta M., Konno H., Tannaka T., et al. Effect of combination therapy with matrix metalloproteinase inhibitor MMI-166 and mitomycin C on the growth and liver metastasis of human colon cancer. Jpn J Cancer Res. 92:2001;688-695.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 688-695
    • Ohta, M.1    Konno, H.2    Tannaka, T.3
  • 58
    • 0034797783 scopus 로고    scopus 로고
    • Improving chemoradiotherapy in rectal cancer
    • Glynne-Jones R., Debus J. Improving chemoradiotherapy in rectal cancer. Oncologist. 6:(Suppl 4):2001;29-34.
    • (2001) Oncologist , vol.6 , Issue.SUPPL. 4 , pp. 29-34
    • Glynne-Jones, R.1    Debus, J.2
  • 59
    • 0001184602 scopus 로고    scopus 로고
    • Pre-operative therapy (PT) with oral uracil and tegafur (UFT) and concomitant irradiation (RT) in operable rectal cancer (RC). Preliminary results of a multicenter phase II study
    • Fernandez-Martos C., Aparicio J., Bosch C., Torregrosa D., Campos J., Vicent J. Pre-operative therapy (PT) with oral uracil and tegafur (UFT) and concomitant irradiation (RT) in operable rectal cancer (RC). Preliminary results of a multicenter phase II study. Proc Am Soc Clin Oncol. 20:2001;148a.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Fernandez-Martos, C.1    Aparicio, J.2    Bosch, C.3    Torregrosa, D.4    Campos, J.5    Vicent, J.6
  • 60
    • 0034304657 scopus 로고    scopus 로고
    • Postoperative radiation therapy for rectal cancer combined with UFT/leucovorin
    • Rosenthal D.I., Haller D.G., Saltz L., Semple D., Minsky B.D. Postoperative radiation therapy for rectal cancer combined with UFT/leucovorin. Oncology (Huntingt). 14:(Suppl 9):2000;59-62.
    • (2000) Oncology (Huntingt) , vol.14 , Issue.SUPPL. 9 , pp. 59-62
    • Rosenthal, D.I.1    Haller, D.G.2    Saltz, L.3    Semple, D.4    Minsky, B.D.5
  • 61
    • 0034304706 scopus 로고    scopus 로고
    • A phase I study. Preoperative UFT/leucovorin and radiation therapy in rectal cancer
    • Hoff P.M., Saad E.D., Janjan N., Skibber J., Pazdur R. A phase I study. Preoperative UFT/leucovorin and radiation therapy in rectal cancer. Oncology (Huntingt). 14:(Suppl 9):2000;56-58.
    • (2000) Oncology (Huntingt) , vol.14 , Issue.SUPPL. 9 , pp. 56-58
    • Hoff, P.M.1    Saad, E.D.2    Janjan, N.3    Skibber, J.4    Pazdur, R.5
  • 62
    • 0003326684 scopus 로고    scopus 로고
    • Phase I study of capecitabine combined with simultaneous radiotherapy in rectal cancer
    • Dunst J., Reese T., Frings S. Phase I study of capecitabine combined with simultaneous radiotherapy in rectal cancer. Proc Am Soc Clin Oncol. 20:2001;149a.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Dunst, J.1    Reese, T.2    Frings, S.3
  • 63
    • 0003326684 scopus 로고    scopus 로고
    • A phase I study of capecitabine combined with radiotherapy for locally advanced potentially operable rectal cancer
    • Ngan S., Zalcberg J., Kell A., et al. A phase I study of capecitabine combined with radiotherapy for locally advanced potentially operable rectal cancer. Proc Am Soc Clin Oncol. 20:2001;149a.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Ngan, S.1    Zalcberg, J.2    Kell, A.3
  • 64
    • 0034193406 scopus 로고    scopus 로고
    • Preclinical evaluation of the orally active camptothecin analog, RFS-2000 (9-nitro-20(S)-camptothecin) as a radiation enhancer
    • Amorino G.P., Hercules S.K., Mohr P.J., Pyo H., Choy H. Preclinical evaluation of the orally active camptothecin analog, RFS-2000 (9-nitro-20(S)-camptothecin) as a radiation enhancer. Int J Radiat Oncol Biol Phys. 47:2000;503-509.
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 503-509
    • Amorino, G.P.1    Hercules, S.K.2    Mohr, P.J.3    Pyo, H.4    Choy, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.