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Volumn 63, Issue 19, 2003, Pages 6187-6194

Effects of oligonucleotide N3′→P5′ thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; FLUORESCEIN; GRN 163; NUCLEOPROTEIN; OLIGONUCLEOTIDE; OLIGONUCLEOTIDE N3',P5' THIOPHOSPHORAMIDATE; PROTEIN P21; PROTEIN P53; RNA; SYNDECAN 1; TELOMERASE; UNCLASSIFIED DRUG;

EID: 0141954014     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (81)

References (31)
  • 1
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • Blackburn, E. H. Switching and signaling at the telomere. Cell, 106: 661-673, 2001.
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 2
    • 0037148342 scopus 로고    scopus 로고
    • Telomeres, aging and cancer: In search of a happy ending
    • Kim, S., Kaminker, P., Campisi, J. Telomeres, aging and cancer: in search of a happy ending. Oncogene, 21: 503-511, 2002.
    • (2002) Oncogene , vol.21 , pp. 503-511
    • Kim, S.1    Kaminker, P.2    Campisi, J.3
  • 3
    • 0037148328 scopus 로고    scopus 로고
    • Telomerase is not an oncogene
    • Harley, C. B. Telomerase is not an oncogene. Oncogene, 21: 494-502, 2002.
    • (2002) Oncogene , vol.21 , pp. 494-502
    • Harley, C.B.1
  • 4
  • 6
    • 0033568462 scopus 로고    scopus 로고
    • Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
    • Zhang, X., Mar, V., Zhou, W., Harrington, L., and Robinson, M. O. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Gene Dev., 13: 2388-2399, 1999.
    • (1999) Gene Dev. , vol.13 , pp. 2388-2399
    • Zhang, X.1    Mar, V.2    Zhou, W.3    Harrington, L.4    Robinson, M.O.5
  • 10
  • 12
    • 0035921689 scopus 로고    scopus 로고
    • Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma
    • Hideshima, T., Nakamura, N., Chauhan, D., and Anderson, K. C. Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma. Oncogene, 20: 5991-6000, 2001.
    • (2001) Oncogene , vol.20 , pp. 5991-6000
    • Hideshima, T.1    Nakamura, N.2    Chauhan, D.3    Anderson, K.C.4
  • 14
    • 0037148567 scopus 로고    scopus 로고
    • Oligonucleotide N3′→P5′ phosphoramidates as efficient telomerase inhibitors
    • Herbert, S. B., Pongracz, K., Shay, J. W., and Gryaznov, S. M. Oligonucleotide N3′→P5′ phosphoramidates as efficient telomerase inhibitors. Oncogene, 21: 638-642, 2002.
    • (2002) Oncogene , vol.21 , pp. 638-642
    • Herbert, S.B.1    Pongracz, K.2    Shay, J.W.3    Gryaznov, S.M.4
  • 15
    • 0037079670 scopus 로고    scopus 로고
    • Allosteric inhibitors of telomerase: Oligonucleotide N3′→ P5′ phosphoramidates
    • Pruzan, R., Pongracz, K., Gietzen, K., Wallweber, G., and Gryaznov, S. Allosteric inhibitors of telomerase: oligonucleotide N3′→P5′ phosphoramidates. Nucleic Acids Res., 30: 559-568, 2002.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 559-568
    • Pruzan, R.1    Pongracz, K.2    Gietzen, K.3    Wallweber, G.4    Gryaznov, S.5
  • 16
    • 0037171586 scopus 로고    scopus 로고
    • Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors
    • Akiyama, M., Yamada, O., Kanda, N., Akita, S., Kawano, T., Ohno, T., Mizoguchi, H., Eto, Y., Anderson, K. C., and Yamada, H. Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors. Cancer Lett., 178: 187-197, 2002.
    • (2002) Cancer Lett. , vol.178 , pp. 187-197
    • Akiyama, M.1    Yamada, O.2    Kanda, N.3    Akita, S.4    Kawano, T.5    Ohno, T.6    Mizoguchi, H.7    Eto, Y.8    Anderson, K.C.9    Yamada, H.10
  • 20
    • 0032530832 scopus 로고    scopus 로고
    • Mad2 transiently associates with an APC/p55 Cdc complex during mitosis
    • Wassmann, K., and Benezra, R. Mad2 transiently associates with an APC/ p55 Cdc complex during mitosis. Proc. Natl., Acad. Sci. USA. 95: 11193-11198, 1998.
    • (1998) Proc. Natl., Acad. Sci. USA , vol.95 , pp. 11193-11198
    • Wassmann, K.1    Benezra, R.2
  • 21
    • 0037085936 scopus 로고    scopus 로고
    • Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells
    • Wang. X., Jin, D. Y., Ng, R. W. M., Feng, H., Wong, Y. C., Cheung, A. L. M., and Tsao, S. W. Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells. Cancer Res., 62: 1662-1668, 2002.
    • (2002) Cancer Res. , vol.62 , pp. 1662-1668
    • Wang, X.1    Jin, D.Y.2    Ng, R.W.M.3    Feng, H.4    Wong, Y.C.5    Cheung, A.L.M.6    Tsao, S.W.7
  • 22
    • 0037427074 scopus 로고    scopus 로고
    • MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells
    • Wang, X., Jin, D-Y., Wong, H. L., Feng, H., Wong, Y-C., and Tsao, S. W. MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells. Oncogene, 22: 109-116, 2003.
    • (2003) Oncogene , vol.22 , pp. 109-116
    • Wang, X.1    Jin, D.-Y.2    Wong, H.L.3    Feng, H.4    Wong, Y.-C.5    Tsao, S.W.6
  • 23
    • 0037178761 scopus 로고    scopus 로고
    • Connecting chromosomes, crisis, and cancer
    • Maser, R. S., and Depinho, R. A. Connecting chromosomes, crisis, and cancer. Science (Wash. DC), 297: 565-569, 2002.
    • (2002) Science (Wash. DC) , vol.297 , pp. 565-569
    • Maser, R.S.1    Depinho, R.A.2
  • 24
    • 0037093322 scopus 로고    scopus 로고
    • Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins
    • Frouin, I., Montecucco, A., Biamonti, G., Hubscher, U., Spadari, S., and Maga, G. Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins. EMBO J., 21: 2485-2495, 2002.
    • (2002) EMBO J. , vol.21 , pp. 2485-2495
    • Frouin, I.1    Montecucco, A.2    Biamonti, G.3    Hubscher, U.4    Spadari, S.5    Maga, G.6
  • 25
    • 0033542119 scopus 로고    scopus 로고
    • Characterization of telomere-binding activity of replication factor C large subunit p140
    • Uchiumi. F., Watanabe, M., and Tanuma, S. Characterization of telomere-binding activity of replication factor C large subunit p140. Biochem. Biophys. Res. Commun., 258: 482-489, 1999.
    • (1999) Biochem. Biophys. Res. Commun. , vol.258 , pp. 482-489
    • Uchiumi, F.1    Watanabe, M.2    Tanuma, S.3
  • 26
    • 0034832956 scopus 로고    scopus 로고
    • Regulation of cellular senescence by p53
    • Itahana, K., Dimri, G., and Campisi, J. Regulation of cellular senescence by p53. Eur. J. Biochem., 268: 2784-2791, 2001.
    • (2001) Eur. J. Biochem. , vol.268 , pp. 2784-2791
    • Itahana, K.1    Dimri, G.2    Campisi, J.3
  • 27
    • 0033553516 scopus 로고    scopus 로고
    • p53 deficiency rescues the adverse effects on telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
    • Linda, C., Artandi, S. E., Shen, Q., Tam, A., Lee, S-L., Gottlieb, G. J., Greider, C. W., and Depinho, R. A. p53 deficiency rescues the adverse effects on telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell, 97: 527-538, 1999.
    • (1999) Cell , vol.97 , pp. 527-538
    • Linda, C.1    Artandi, S.E.2    Shen, Q.3    Tam, A.4    Lee, S.-L.5    Gottlieb, G.J.6    Greider, C.W.7    Depinho, R.A.8
  • 28
    • 0038277105 scopus 로고    scopus 로고
    • Tumor cell senescence in cancer treatment
    • Roninson, I. B. Tumor cell senescence in cancer treatment. Cancer Res., 63: 2705-2715, 2003.
    • (2003) Cancer Res. , vol.63 , pp. 2705-2715
    • Roninson, I.B.1
  • 30
    • 0037126303 scopus 로고    scopus 로고
    • Cip1 Cdk inhibitor influences the outcome of p53 response to DNA damage
    • Cip1 Cdk inhibitor influences the outcome of p53 response to DNA damage. Nature (Lond.), 419: 729-734, 2002.
    • (2002) Nature (Lond.) , vol.419 , pp. 729-734
    • Seoane, J.1    Le, H.V.2    Massagué, J.3
  • 31
    • 0038235696 scopus 로고    scopus 로고
    • Telomerase and telomere length in multiple myeloma: Correlation with disease heterogeneity, cytogenetic status, and overall survival
    • Wu, K. D., Orme, L. M., Shaughnessy, J., Jr., Jacobson, J., Barlogie, B., and Moore, M. A. S. Telomerase and telomere length in multiple myeloma: correlation with disease heterogeneity, cytogenetic status, and overall survival. Blood, 101: 4982-4989, 2003.
    • (2003) Blood , vol.101 , pp. 4982-4989
    • Wu, K.D.1    Orme, L.M.2    Shaughnessy J., Jr.3    Jacobson, J.4    Barlogie, B.5    Moore, M.A.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.