-
1
-
-
0035929353
-
Switching and signaling at the telomere
-
Blackburn, E. H. Switching and signaling at the telomere. Cell, 106: 661-673, 2001.
-
(2001)
Cell
, vol.106
, pp. 661-673
-
-
Blackburn, E.H.1
-
2
-
-
0037148342
-
Telomeres, aging and cancer: In search of a happy ending
-
Kim, S., Kaminker, P., Campisi, J. Telomeres, aging and cancer: in search of a happy ending. Oncogene, 21: 503-511, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 503-511
-
-
Kim, S.1
Kaminker, P.2
Campisi, J.3
-
3
-
-
0037148328
-
Telomerase is not an oncogene
-
Harley, C. B. Telomerase is not an oncogene. Oncogene, 21: 494-502, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 494-502
-
-
Harley, C.B.1
-
4
-
-
0033455559
-
Inhibition of human telomense in immortal human cells leads to progressive telomere shortening and cell death
-
Herbert, B. S., Pitts, A. E., Baker, S. I., Hamilton, S. E., Wright, W. E., Shay, J. W., and Corey, D. R. Inhibition of human telomense in immortal human cells leads to progressive telomere shortening and cell death. Proc. Natl. Acad. Sci. USA, 96: 14276-14281, 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14276-14281
-
-
Herbert, B.S.1
Pitts, A.E.2
Baker, S.I.3
Hamilton, S.E.4
Wright, W.E.5
Shay, J.W.6
Corey, D.R.7
-
5
-
-
0032828652
-
Inhibition of telomerase limits the growth of human cancer cells
-
Hahn, W. C., Stewart, S. A., Brooks, M. W., York, S. G., Eaton, E., Kurachi, A., Beijersbergen, R. L., Knoll, J. H. M., Meyerson, M., and Weinberg, R. A. Inhibition of telomerase limits the growth of human cancer cells. Nat. Med., 5: 1164-1170, 1999.
-
(1999)
Nat. Med.
, vol.5
, pp. 1164-1170
-
-
Hahn, W.C.1
Stewart, S.A.2
Brooks, M.W.3
York, S.G.4
Eaton, E.5
Kurachi, A.6
Beijersbergen, R.L.7
Knoll, J.H.M.8
Meyerson, M.9
Weinberg, R.A.10
-
6
-
-
0033568462
-
Telomere shortening and apoptosis in telomerase-inhibited human tumor cells
-
Zhang, X., Mar, V., Zhou, W., Harrington, L., and Robinson, M. O. Telomere shortening and apoptosis in telomerase-inhibited human tumor cells. Gene Dev., 13: 2388-2399, 1999.
-
(1999)
Gene Dev.
, vol.13
, pp. 2388-2399
-
-
Zhang, X.1
Mar, V.2
Zhou, W.3
Harrington, L.4
Robinson, M.O.5
-
7
-
-
0035793794
-
Telomerase activity in plasma cell dyscrasias
-
Xu, D., Zheng, C., Bergenbrant, S., Holm, G., Bjorkholm, M., Yi, Q., and Gruber, A. Telomerase activity in plasma cell dyscrasias. Br. J. Cancer, 84: 621-625, 2001.
-
(2001)
Br. J. Cancer
, vol.84
, pp. 621-625
-
-
Xu, D.1
Zheng, C.2
Bergenbrant, S.3
Holm, G.4
Bjorkholm, M.5
Yi, Q.6
Gruber, A.7
-
8
-
-
0037089647
-
Clinical significance of telomerase activity in multiple myeloma
-
Shiratsuchi, M., Muta, K., Abe, Y., Motomura, S., Taguchi, F., Takatsuki, H., Uike, N., Umemura, T., Nawata, H., and Nishimura, J. Clinical significance of telomerase activity in multiple myeloma. Cancer (Phila.), 94: 2232-2238, 2002.
-
(2002)
Cancer (Phila.)
, vol.94
, pp. 2232-2238
-
-
Shiratsuchi, M.1
Muta, K.2
Abe, Y.3
Motomura, S.4
Taguchi, F.5
Takatsuki, H.6
Uike, N.7
Umemura, T.8
Nawata, H.9
Nishimura, J.10
-
9
-
-
0037158513
-
Activation of NF-κB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple mycloma cells: Therapeutic implications
-
Mitsiades, C. S., Mitsiades, N., Poulaki, V., Richardson, P. G., Schlossman, R., Akiyama, M., Chauhan, D., Hideshima, T., Munshi, N., Treon, S. P., and Anderson, K. C. Activation of NF-κB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple mycloma cells: therapeutic implications. Oncogene, 21: 5673-5683, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 5673-5683
-
-
Mitsiades, C.S.1
Mitsiades, N.2
Poulaki, V.3
Richardson, P.G.4
Schlossman, R.5
Akiyama, M.6
Chauhan, D.7
Hideshima, T.8
Munshi, N.9
Treon, S.P.10
Anderson, K.C.11
-
10
-
-
0031225483
-
IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade
-
Ogata, A., Chauhan, D., Teoh, G., Treon, S. P., Urashima, M., Schlossman, R. L., and Anderson, K. C. IL-6 triggers cell growth via the Ras-dependent mitogen-activated protein kinase cascade. J. Immunol., 159: 2212-2221, 1997.
-
(1997)
J. Immunol.
, vol.159
, pp. 2212-2221
-
-
Ogata, A.1
Chauhan, D.2
Teoh, G.3
Treon, S.P.4
Urashima, M.5
Schlossman, R.L.6
Anderson, K.C.7
-
11
-
-
0034623059
-
SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells
-
Chauhan, D., Pandey, P., Hideshima, T., Treon, S., Raje, N., Davies, F. E., Shima, Y., Tai, Y. T., Rosen, S., Avraham, S., Kharbanda, S., and Anderson, K. C. SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells. J. Biol. Chem., 275: 27845-27850, 2000.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27845-27850
-
-
Chauhan, D.1
Pandey, P.2
Hideshima, T.3
Treon, S.4
Raje, N.5
Davies, F.E.6
Shima, Y.7
Tai, Y.T.8
Rosen, S.9
Avraham, S.10
Kharbanda, S.11
Anderson, K.C.12
-
12
-
-
0035921689
-
Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma
-
Hideshima, T., Nakamura, N., Chauhan, D., and Anderson, K. C. Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma. Oncogene, 20: 5991-6000, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 5991-6000
-
-
Hideshima, T.1
Nakamura, N.2
Chauhan, D.3
Anderson, K.C.4
-
13
-
-
0036645153
-
Cytokines modulate telomerase activity in a human multiple myeloma cell line
-
Akiyama, M., Hideshima, T., Hayashi, T., Tai, Y. T., Mitsiades, C. S., Mitsiades, N., Chauhan, D., Richardson, P., Munshi, N. C., and Anderson, K. C. Cytokines modulate telomerase activity in a human multiple myeloma cell line. Cancer Res., 62: 3876-3882, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 3876-3882
-
-
Akiyama, M.1
Hideshima, T.2
Hayashi, T.3
Tai, Y.T.4
Mitsiades, C.S.5
Mitsiades, N.6
Chauhan, D.7
Richardson, P.8
Munshi, N.C.9
Anderson, K.C.10
-
14
-
-
0037148567
-
Oligonucleotide N3′→P5′ phosphoramidates as efficient telomerase inhibitors
-
Herbert, S. B., Pongracz, K., Shay, J. W., and Gryaznov, S. M. Oligonucleotide N3′→P5′ phosphoramidates as efficient telomerase inhibitors. Oncogene, 21: 638-642, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 638-642
-
-
Herbert, S.B.1
Pongracz, K.2
Shay, J.W.3
Gryaznov, S.M.4
-
15
-
-
0037079670
-
Allosteric inhibitors of telomerase: Oligonucleotide N3′→ P5′ phosphoramidates
-
Pruzan, R., Pongracz, K., Gietzen, K., Wallweber, G., and Gryaznov, S. Allosteric inhibitors of telomerase: oligonucleotide N3′→P5′ phosphoramidates. Nucleic Acids Res., 30: 559-568, 2002.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 559-568
-
-
Pruzan, R.1
Pongracz, K.2
Gietzen, K.3
Wallweber, G.4
Gryaznov, S.5
-
16
-
-
0037171586
-
Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors
-
Akiyama, M., Yamada, O., Kanda, N., Akita, S., Kawano, T., Ohno, T., Mizoguchi, H., Eto, Y., Anderson, K. C., and Yamada, H. Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors. Cancer Lett., 178: 187-197, 2002.
-
(2002)
Cancer Lett.
, vol.178
, pp. 187-197
-
-
Akiyama, M.1
Yamada, O.2
Kanda, N.3
Akita, S.4
Kawano, T.5
Ohno, T.6
Mizoguchi, H.7
Eto, Y.8
Anderson, K.C.9
Yamada, H.10
-
17
-
-
2642610318
-
Myc activates telomerase
-
Wang, J., Xie, L. Y., Allan, S., Beach, D., and Hannon, G. J. Myc activates telomerase. Genes Dev., 12: 1769-1774, 1998.
-
(1998)
Genes Dev.
, vol.12
, pp. 1769-1774
-
-
Wang, J.1
Xie, L.Y.2
Allan, S.3
Beach, D.4
Hannon, G.J.5
-
18
-
-
0036336135
-
Telomerase inhibitors as anticancer therapy
-
Akiyama, M., Hideshima, T., Munshi, N. C., and Anderson, K. C. Telomerase inhibitors as anticancer therapy. Curr. Med. Chem. Anti-Canc Agents, 2: 567-575, 2002.
-
(2002)
Curr. Med. Chem. Anti-Canc Agents
, vol.2
, pp. 567-575
-
-
Akiyama, M.1
Hideshima, T.2
Munshi, N.C.3
Anderson, K.C.4
-
19
-
-
4243937106
-
A highly selective telomerase inhibitor limiting human cancer cell proliferation
-
Damm, K., Hemmann, U., Chesa, P. G., Hauel, N., Kauffmann, I., Priepke, H., Niestroj, C., Daiber, C., Enenkel, B., Guilliard, B., Lauritsch, I., Muller, E., Pascolo, E., Sauter, G., Pantic, M., Martens, U. M., Wenz, C., Lingner, J., Kraut, N., Rettig, W. J., and Schnapp, A. A highly selective telomerase inhibitor limiting human cancer cell proliferation. EMBO J., 20: 6958-6968, 2001.
-
(2001)
EMBO J.
, vol.20
, pp. 6958-6968
-
-
Damm, K.1
Hemmann, U.2
Chesa, P.G.3
Hauel, N.4
Kauffmann, I.5
Priepke, H.6
Niestroj, C.7
Daiber, C.8
Enenkel, B.9
Guilliard, B.10
Lauritsch, I.11
Muller, E.12
Pascolo, E.13
Sauter, G.14
Pantic, M.15
Martens, U.M.16
Wenz, C.17
Lingner, J.18
Kraut, N.19
Rettig, W.J.20
Schnapp, A.21
more..
-
20
-
-
0032530832
-
Mad2 transiently associates with an APC/p55 Cdc complex during mitosis
-
Wassmann, K., and Benezra, R. Mad2 transiently associates with an APC/ p55 Cdc complex during mitosis. Proc. Natl., Acad. Sci. USA. 95: 11193-11198, 1998.
-
(1998)
Proc. Natl., Acad. Sci. USA
, vol.95
, pp. 11193-11198
-
-
Wassmann, K.1
Benezra, R.2
-
21
-
-
0037085936
-
Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells
-
Wang. X., Jin, D. Y., Ng, R. W. M., Feng, H., Wong, Y. C., Cheung, A. L. M., and Tsao, S. W. Significance of MAD2 expression to mitotic checkpoint control in ovarian cancer cells. Cancer Res., 62: 1662-1668, 2002.
-
(2002)
Cancer Res.
, vol.62
, pp. 1662-1668
-
-
Wang, X.1
Jin, D.Y.2
Ng, R.W.M.3
Feng, H.4
Wong, Y.C.5
Cheung, A.L.M.6
Tsao, S.W.7
-
22
-
-
0037427074
-
MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells
-
Wang, X., Jin, D-Y., Wong, H. L., Feng, H., Wong, Y-C., and Tsao, S. W. MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells. Oncogene, 22: 109-116, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 109-116
-
-
Wang, X.1
Jin, D.-Y.2
Wong, H.L.3
Feng, H.4
Wong, Y.-C.5
Tsao, S.W.6
-
23
-
-
0037178761
-
Connecting chromosomes, crisis, and cancer
-
Maser, R. S., and Depinho, R. A. Connecting chromosomes, crisis, and cancer. Science (Wash. DC), 297: 565-569, 2002.
-
(2002)
Science (Wash. DC)
, vol.297
, pp. 565-569
-
-
Maser, R.S.1
Depinho, R.A.2
-
24
-
-
0037093322
-
Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins
-
Frouin, I., Montecucco, A., Biamonti, G., Hubscher, U., Spadari, S., and Maga, G. Cell cycle-dependent dynamic association of cyclin/Cdk complexes with human DNA replication proteins. EMBO J., 21: 2485-2495, 2002.
-
(2002)
EMBO J.
, vol.21
, pp. 2485-2495
-
-
Frouin, I.1
Montecucco, A.2
Biamonti, G.3
Hubscher, U.4
Spadari, S.5
Maga, G.6
-
25
-
-
0033542119
-
Characterization of telomere-binding activity of replication factor C large subunit p140
-
Uchiumi. F., Watanabe, M., and Tanuma, S. Characterization of telomere-binding activity of replication factor C large subunit p140. Biochem. Biophys. Res. Commun., 258: 482-489, 1999.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.258
, pp. 482-489
-
-
Uchiumi, F.1
Watanabe, M.2
Tanuma, S.3
-
26
-
-
0034832956
-
Regulation of cellular senescence by p53
-
Itahana, K., Dimri, G., and Campisi, J. Regulation of cellular senescence by p53. Eur. J. Biochem., 268: 2784-2791, 2001.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2784-2791
-
-
Itahana, K.1
Dimri, G.2
Campisi, J.3
-
27
-
-
0033553516
-
p53 deficiency rescues the adverse effects on telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis
-
Linda, C., Artandi, S. E., Shen, Q., Tam, A., Lee, S-L., Gottlieb, G. J., Greider, C. W., and Depinho, R. A. p53 deficiency rescues the adverse effects on telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis. Cell, 97: 527-538, 1999.
-
(1999)
Cell
, vol.97
, pp. 527-538
-
-
Linda, C.1
Artandi, S.E.2
Shen, Q.3
Tam, A.4
Lee, S.-L.5
Gottlieb, G.J.6
Greider, C.W.7
Depinho, R.A.8
-
28
-
-
0038277105
-
Tumor cell senescence in cancer treatment
-
Roninson, I. B. Tumor cell senescence in cancer treatment. Cancer Res., 63: 2705-2715, 2003.
-
(2003)
Cancer Res.
, vol.63
, pp. 2705-2715
-
-
Roninson, I.B.1
-
29
-
-
0037623356
-
p53-dependent checkpoint pathway prevents replication
-
Vaziri, C., Saxena, S., Jeon, Y., Lee, C., Murata, K., Machida, Y., Wagle, N., Hwang, D. S., and Dutta, A. A. p53-dependent checkpoint pathway prevents replication. Mol. Cell, 11: 997-1008, 2003.
-
(2003)
Mol Cell
, vol.11
, pp. 997-1008
-
-
Vaziri, C.1
Saxena, S.2
Jeon, Y.3
Lee, C.4
Murata, K.5
Machida, Y.6
Wagle, N.7
Hwang, D.S.8
Dutta, A.A.9
-
30
-
-
0037126303
-
Cip1 Cdk inhibitor influences the outcome of p53 response to DNA damage
-
Cip1 Cdk inhibitor influences the outcome of p53 response to DNA damage. Nature (Lond.), 419: 729-734, 2002.
-
(2002)
Nature (Lond.)
, vol.419
, pp. 729-734
-
-
Seoane, J.1
Le, H.V.2
Massagué, J.3
-
31
-
-
0038235696
-
Telomerase and telomere length in multiple myeloma: Correlation with disease heterogeneity, cytogenetic status, and overall survival
-
Wu, K. D., Orme, L. M., Shaughnessy, J., Jr., Jacobson, J., Barlogie, B., and Moore, M. A. S. Telomerase and telomere length in multiple myeloma: correlation with disease heterogeneity, cytogenetic status, and overall survival. Blood, 101: 4982-4989, 2003.
-
(2003)
Blood
, vol.101
, pp. 4982-4989
-
-
Wu, K.D.1
Orme, L.M.2
Shaughnessy J., Jr.3
Jacobson, J.4
Barlogie, B.5
Moore, M.A.S.6
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