Functional analysis of the Caenorhabditis elegans UNC-73B PH domain demonstrates a role in activation of the Rac GTPase in vitro and axon guidance in vivo

Molecular and Cellular Biology

Volumn 23, Issue 19, 2003, Pages 6823-6835

  Kubiseski, Terrance J ^a   Culotti, Joe ^a,b   Pawson, Tony ^a,b  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; ARGININE; GLUTAMIC ACID; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; LYSINE; PHOSPHATIDYLINOSITIDE; PHOSPHOLIPID; PLECKSTRIN; PROTEIN UNC 73B; RAC GUANOSINE TRIPHOSPHATASE; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CAENORHABDITIS ELEGANS; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE MUTATION; MICROINJECTION; MOTONEURON; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PLECKSTRIN HOMOLOGY DOMAIN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANIMALS, GENETICALLY MODIFIED; AXONS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CELL LINE; FIBROBLASTS; GENE EXPRESSION REGULATION; KINETICS; MOLECULAR SEQUENCE DATA; MOTOR NEURONS; NERVE TISSUE PROTEINS; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOLIPIDS; RAC GTP-BINDING PROTEINS; RATS; RECOMBINANT FUSION PROTEINS;

CAENORHABDITIS; CAENORHABDITIS ELEGANS;

EID: 0141781088     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.23.19.6823-6835.2003     Document Type: Article

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