Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components

Biochemical Journal

Volumn 351, Issue 1, 2000, Pages 173-182

  Fleming, I N ^a   Gray, A ^a   Downes, C P ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Membrane ruffling; Phosphatidylinositol 3,4,5 trisphosphate; Pleckstrin homology domains; Rac1

Indexed keywords

GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE; INOSITOL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TIAM 1; RAC PROTEIN; UNCLASSIFIED DRUG; WORTMANNIN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME MECHANISM; ENZYME REGULATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; REGULATORY MECHANISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; ANIMAL; BLOOD PROTEINS; CELL LINE; CELL MEMBRANE; ENZYME ACTIVATION; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMAN; MICE; MUTATION; PHOSPHATIDYLINOSITOLS; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RAC1 GTP-BINDING PROTEIN; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; SUPPORT, NON-U.S. GOV'T;

EID: 0034306279     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3510173     Document Type: Article

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