Cellular specificity of HIV-1 replication can be controlled by LTR sequences

Virology

Volumn 314, Issue 2, 2003, Pages 680-695

  Reed Inderbitzin, Edward ^a,c   Maury, Wendy ^b  

^a UNIVERSITY OF SOUTH DAKOTA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Cell tropism; EIAV; Enhancer; Equine infectious anemia virus; HIV; Human immunodeficiency virus; Macrophage; PU.1; T cell

Indexed keywords

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING SITE; CELL SPECIFICITY; CHIMERA; CLONE; ENHANCER REGION; EQUINE INFECTIOUS ANEMIA VIRUS; GENE EXPRESSION REGULATION; GENE SEQUENCE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; METHYLATION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; PROTEIN MOTIF; T LYMPHOCYTE; VIRION; VIRUS GENE; VIRUS INFECTIVITY; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

EQUIDAE; EQUINE INFECTIOUS ANEMIA VIRUS; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0141758293     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0042-6822(03)00508-7     Document Type: Article

References (75)

1. Bagasra O., Wright S.D., Seshamma T., Oakes J.W., Pomerantz R.J. CD14 is involved in control of human immunodeficiency virus type 1 expression in latently infected cells by lipopolysaccharide. Proc. Natl. Acad. Sci. USA. 89:(14):1992;6285-6289.
2. Bieniasz P.D., Grdina T.A., Bogerd H.P., Cullen B.R. Recruitment of a protein complex containing Tat and cyclin T1 to TAR governs the species specificity of HIV-1 Tat. EMBO J. 17:(23):1998;7056-7065.
3. Blackard J.T., Renjifo B., Chaplin B., Msamanga G., Fawzi W., Essex M. Diversity of the HIV-1 long terminal repeat following mother-to-child transmission. Virology. 274:(2):2000;402-411.
4. Carpenter S., Alexandersen S., Long M.J., Perryman S., Chesebro B. Identification of a hypervariable region in the long terminal repeat of equine infectious anemia virus. J. Virol. 65:(3):1991;1605-1610.
5. Carr J.K., Salminen M.O., Koch C., Gotte D., Artenstein A.W., Hegerich P.A., St Louis D., Burke D.S., Mccutchan F.E. Full-length sequence and mosaic structure of a human immunodeficiency virus type 1 isolate from Thailand. J. Virol. 70:(9):1996;5935-5943.
6. Carvalho M., Derse D. Physical and functional characterization of transcriptional control elements in the equine infectious anemia virus promoter. J. Virol. 67:(4):1993;2064-2074.
7. Carvalho M., Derse D. The PU.1/Spi-1 proto-oncogene is a transcriptional regulator of a lentivirus promoter. J. Virol. 67:(7):1993;3885-3890.
8. Celander D., Haseltine W.A. Tissue-specific transcription preference as a determinant of cell tropism and leukaemogenic potential of murine retroviruses. Nature. 312:(5990):1984;159-162.
9. Chang L.J., Mcnulty E., Martin M. Human immunodeficiency viruses containing heterologous enhancer/promoters are replication competent and exhibit different lymphocyte tropisms. J. Virol. 67:(2):1993;743-752.
10. Chesebro B., Wehrly K., Nishio J., Perryman S. Mapping of independent V3 envelope determinants of human immunodeficiency virus type 1 macrophage tropism and syncytium formation in lymphocytes. J. Virol. 70:(12):1996;9055-9059.
11. Choi J.K., Hoang N., Vilardi A.M., Conrad P., Emerson S.G., Gewirtz A.M. Hybrid HIV/MSCV LTR enhances transgene expression of lentiviral vectors in human CD34(+) hematopoietic cells. Stem Cells. 19:(3):2001;236-246.
12. Chun R.F., Semmes O.J., Neuveut C., Jeang K.T. Modulation of Sp1 phosphorylation by human immunodeficiency virus type 1 Tat. J. Virol. 72:(4):1998;2615-2629.
13. Clouse K.A., Robbins P.B., Fernie B., Ostrove J.M., Fauci A.S. Viral antigen stimulation of the production of human monokines capable of regulating HIV1 expression. J. Immunol. 143:(2):1989;470-475.
14. Corboy J.R., Garl P.J. HIV-1 LTR DNA sequence variation in brain-derived isolates. J. Neurovirol. 3:(5):1997;331-341.
15. Dickie P., Gazzinelli R., Chang L.J. Models of HIV type 1 proviral gene expression in wild-type HIV and MLV/HIV transgenic mice. AIDS Res. Hum. Retroviruses. 12:(12):1996;1103-1116.
16. Donaldson Y.K., Bell J.E., Holmes E.C., Hughes E.S., Brown H.K., Simmonds P. In vivo distribution and cytopathology of variants of human immunodeficiency virus type 1 showing restricted sequence variability in the V3 loop. J. Virol. 68:(9):1994;5991-6005.
17. Eckstein D.A., Sherman M.P., Penn M.L., Chin P.S., De Noronha C.M., Greene W.C., Goldsmith M.A. HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells. J. Exp. Med. 194:(10):2001;1407-1419.
18. Feuer G., Fan H. Substitution of murine transthyretin (prealbumin) regulatory sequences into the Moloney murine leukemia virus long terminal repeat yields infectious virus with altered biological properties. J. Virol. 64:(12):1990;6130-6140.
19. Flaherty M.T., Hauer D.A., Mankowski J.L., Zink M.C., Clements J.E. Molecular and biological characterization of a neurovirulent molecular clone of simian immunodeficiency virus. J. Virol. 71:(8):1997;5790-5798.
20. Freundlich B., Avdalovic N. Use of gelatin/plasma coated flasks for isolating human peripheral blood monocytes. Immunol. Methods. 62:1983;31-37.
21. Garber M.E., Wei P., Kewalramani V.N., Mayall T.P., Herrmann C.H., Rice A.P., Littman D.R., Jones K.A. The interaction between HIV-1 Tat and human cyclin T1 requires zinc and a critical cysteine residue that is not conserved in the murine CycT1 protein. Genes Dev. 12:(22):1998;3512-3527.
22. Ghorpade A., Nukuna A., Che M., Haggerty S., Persidsky Y., Carter E., Carhart L., Shafer L., Gendelman H.E. Human immunodeficiency virus neurotropism an analysis of viral replication and cytopathicity for divergent strains in monocytes and microglia . J. Virol. 72:(4):1998;3340-3350.
23. Gorman C., Padmanabhan R., Howard B.H. High efficiency DNA-mediated transformation of primate cells. Science. 221:(4610):1983;551-553.
24. Graham F.L., Smiley J., et al. Characteristics of a human cell line transformed by DNA from human adenovirus type 5. J. Gen. Virol. 36:(1):1977;59-74.
25. Grivel J.C., Margolis L.B. CCR5- and CXCR4-tropic HIV-1 are equally cytopathic for their T-cell targets in human lymphoid tissue. Nat. Med. 5:(3):1999;344-346.
26. Hamaguchi I., Woods N.B., Panagopoulos I., Andersson E., Mikkola H., Fahlman C., Zufferey R., Carlsson L., Trono D., Karlsson S. Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro. J. Virol. 74:(22):2000;10778-10784.
27. Henderson A.J., Calame K.L. CCAAT/enhancer binding protein (C/EBP) sites are required for HIV-1 replication in primary macrophages but not CD4(+) T cells. Proc. Natl. Acad. Sci. USA. 94:(16):1997;8714-8719.
28. Henderson A.J., Connor R.I., Calame K.L. C/EBP activators are required for HIV-1 replication and proviral induction in monocytic cell lines. Immunity. 5:(1):1996;91-101.
29. Henderson A.J., Zou X., Calame K.L. C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes. J. Virol. 69:(9):1995;5337-5344.
30. Hines R., Maury W. DH82 cells a macrophage cell line for the replication and study of equine infectious anemia virus . J. Virol. Methods. 95:(1-2):2001;47-56.
31. Huang L.M., Jeang K.T. Increased spacing between Sp1 and TATAA renders human immunodeficiency virus type 1 replication defective implication for Tat function . J. Virol. 67:(12):1993;6937-6944.
32. Hunt G.M., Papathanasopoulos M.A., Gray G.E., Tiemessen C.T. Characterisation of near-full length genome sequences of three South African human immunodeficiency virus type 1 subtype C isolates. Virus Genes. 26:(1):2003;49-56.
33. Igarashi T., Brown C.R., Endo Y., Buckler-White A., Plishka R., Bischofberger N., Hirsch V., Martin M.A. Macrophage are the principal reservoir and sustain high virus loads in rhesus macaques after the depletion of CD4+ T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV) implications for HIV-1 infections of humans . Proc. Natl. Acad. Sci. USA. 98:(2):2001;658-663.
34. Indraccolo S., Minuzzo S., Roccaforte F., Zamarchi R., Habeler W., Stievano L., Tosello V., Klein D., Gunzburg W.H., Basso G., Chieco-Bianchi L., Amadori A. Effects of CD2 locus control region sequences on gene expression by retroviral and lentiviral vectors. Blood. 98:(13):2001;3607-3617.
35. Iwakuma T., Cui Y., Chang L.J. Self-inactivating lentiviral vectors with U3 and U5 modifications. Virology. 261:(1):1999;120-132.
36. Jeang K.T., Chun R., Lin N.H., Gatignol A., Glabe C.G., Fan H. In vitro and in vivo binding of human immunodeficiency virus type 1 Tat protein and Sp1 transcription factor. J. Virol. 67:(10):1993;6224-6233.
37. Kamine J., Chinnadurai G. Synergistic activation of the human immunodeficiency virus type 1 promoter by the viral Tat protein and cellular transcription factor Sp1. J. Virol. 66:(6):1992;3932-3936.
38. Kamine J., Subramanian T., Chinnadurai G. Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 Tat protein. Proc. Natl. Acad. Sci. USA. 88:(19):1991;8510-8514.
39. Koken S.E., Van Wamel J.L., Goudsmit J., Berkhout B., Geelen J.L. Natural variants of the HIV-1 long terminal repeat analysis of promoters with duplicated DNA regulatory motifs . Virology. 191:(2):1992;968-972.
40. Lambotte O., Taoufik Y., De Goer M.G., Wallon C., Goujard C., Delfraissy J.F. Detection of infectious HIV in circulating monocytes from patients on prolonged highly active antiretroviral therapy. J. Acquir. Immune Defic. Syndr. 23:(2):2000;114-119.
41. Leonard J., Parrott C., Buckler-White A.J., Turner W., Ross E.K., Martin M.A., Rabson A.B. The NF-kappa B binding sites in the human immunodeficiency virus type 1 long terminal repeat are not required for virus infectivity. J. Virol. 63:(11):1989;4919-4924.
42. Lin H.C., Bodkin M., Lal R.B., Rabson A.B. Selective infection of human T-lymphotropic virus type 1 (HTLV-1)-infected cells by chimeric human immunodeficiency viruses containing HTLV-1 tax response elements in the long terminal repeat. J. Virol. 69:(11):1995;7216-7225.
43. Lodie T.A., Reiner M., Coniglio S., Viglianti G., Fenton M.J. Both PU.1 and nuclear factor-kappa B mediate lipopolysaccharide-induced HIV-1 long terminal repeat transcription in macrophages. J. Immunol. 161:(1):1998;268-276.
44. Lotti F., Menguzzato E., Rossi C., Naldini L., Ailles L., Mavilio F., Ferrari G. Transcriptional targeting of lentiviral vectors by long terminal repeat enhancer replacement. J. Virol. 76:(8):2002;3996-4007.
45. Malkevitch N., Mcdermott D.H., Yi Y., Grivel J.C., Schols D., De Clercq E., Murphy P.M., Glushakova S., Collman R.G., Margolis L. Coreceptor choice and T cell depletion by R5, X4, and R5X4 HIV-1 variants in CCR5-deficient (CCR5delta32) and normal human lymphoid tissue. Virology. 281:(2):2001;239-247.
46. Maury W. Monocyte maturation controls expression of equine infectious anemia virus. J. Virol. 68:(10):1994;6270-6279.
47. Maury W., Bradley S., Wright B., Hines R. Cell specificity of the transcription-factor repertoire used by a lentivirus motifs important for expression of equine infectious anemia virus in nonmonocytic cells . Virology. 267:(2):2000;267-278.
48. Maury W., Perryman S., Oaks J.L., Seid B.K., Crawford T., McGuire T., Carpenter S. Localized sequence heterogeneity in the long terminal repeats of in vivo isolates of equine infectious anemia virus. J. Virol. 71:(7):1997;4929-4937.
49. McAllister J.J., Phillips D., Millhouse S., Conner J., Hogan T., Ross H.L., Wigdahl B. Analysis of the HIV-1 LTR NF-kappaB-proximal Sp site III evidence for cell type-specific gene regulation and viral replication . Virology. 274:(2):2000;262-277.
50. McNearney T., Hornickova Z., Kloster B., Birdwell A., Storch G.A., Polmar S.H., Arens M., Ratner L. Evolution of sequence divergence among human immunodeficiency virus type 1 isolates derived from a blood donor and a recipient. Pediatr. Res. 33:(1):1993;36-42.
51. Moreau-Gaudry F., Xia P., Jiang G., Perelman N.P., Bauer G., Ellis J., Surinya K.H., Mavilio F., Shen C.K., Malik P. High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors. Blood. 98:(9):2001;2664-2672.
52. Nagashunmugam T., Velpandi A., Otsuka T., Cartas M., Srinivasan A. Analysis of the viral determinants underlying replication kinetics and cellular tropism of human immunodeficiency virus. Pathobiology. 60:(4):1992;234-245.
53. Overhauser J., Fan H. Generation of glucocorticoid-responsive Moloney murine leukemia virus by insertion of regulatory sequences from murine mammary tumor virus into the long terminal repeat. J. Virol. 54:(1):1985;133-144.
54. Park F., Kay M.A. Modified HIV-1 based lentiviral vectors have an effect on viral transduction efficiency and gene expression in vitro and in vivo. Mol. Ther. 4:(3):2001;164-173.
55. Platt E.J., Wehrly K., Kuhmann S.E., Chesebro B., Kabat D. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J. Virol. 72:(4):1998; 2855-2864.
56. Pomerantz R.J., Feinberg M.B., Andino R., Baltimore D. The long terminal repeat is not a major determinant of the cellular tropism of human immunodeficiency virus type 1. J. Virol. 65:(2):1991;1041-1045.
57. Ramezani A., Hawley T.S., Hawley R.G. Lentiviral vectors for enhanced gene expression in human hematopoietic cells. Mol. Ther. 2:(5):2000;458-469.
58. Rich E.A., Chen I.S., Zack J.A., Leonard M.L., O'Brien W.A. Increased susceptibility of differentiated mononuclear phagocytes to productive infection with human immunodeficiency virus-1 (HIV-1). J. Clin. Invest. 89:(1):1992;176-183.
59. Rosen C.A., Haseltine W.A., Lenz J., Ruprecht R., Cloyd M.W. Tissue selectivity of murine leukemia virus infection is determined by long terminal repeat sequences. J. Virol. 55:(3):1985;862-866.
60. Ross E.K., Buckler-White A.J., Rabson A.B., Englund G., Martin M.A. Contribution of NF-kappa B and Sp1 binding motifs to the replicative capacity of human immunodeficiency virus type 1 distinct patterns of viral growth are determined by T-cell types . J. Virol. 65:(8):1991;4350-4358.
61. Ross H.L., Nonnemacher M.R., Hogan T.H., Quiterio S.J., Henderson A., Mcallister J.J., Krebs F.C., Wigdahl B. Interaction between CCAAT/enhancer binding protein and cyclic AMP response element binding protein 1 regulates human immunodeficiency virus type 1 transcription in cells of the monocyte/macrophage lineage. J. Virol. 75:(4):2001;1842-1856.
62. Rousseau C., Abrams E., Lee M., Urbano R., King M.C. Long terminal repeat and nef gene variants of human immunodeficiency virus type 1 in perinatally infected long-term survivors and rapid progressors. AIDS Res. Hum. Retroviruses. 13:(18):1997;1611-1623.
63. Shaw J.P., Utz P.J., Durand D.B., Toole J.J., Emmel E.A., Crabtree G.R. Identification of a putative regulator of early T cell activation genes. Science. 241:(4862):1988;202-205.
64. Sheridan P.L., Sheline C.T., Cannon K., Voz M.L., Pazin M.J., Kadonaga J.T., Jones K.A. Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome- assembled DNA in vitro. Genes Dev. 9:(17):1995;2090-2104.
65. Simm M., Chao W., Pekarskaya O., Sova P., Gupta P., Balachandran R., Volsky D.J. Genetic variability and function of the long terminal repeat from syncytium-inducing and non-syncytium-inducing human immunodeficiency virus type 1. AIDS Res. Hum. Retroviruses. 12:(9):1996;801-809.
66. Taube R., Fujinaga K., Irwin D., Wimmer J., Geyer M., Peterlin B.M. Interactions between equine cyclin T1, Tat, and TAR are disrupted by a leucine-to-valine substitution found in human cyclin T1. J. Virol. 74:(2):2000;892-898.
67. Van Den Hoff M.J., Moorman A.F., Lamers W.H. Electroporation in "intracellular" buffer increases cell survival. Nucleic Acids Res. 20:(11):1992;2902.
68. Van't Wout A.B., Kootstra N.A., Mulder-Kampinga G.A., Albrecht-Van Lent N., Scherpbier H.J., Veenstra J., Boer K., Coutinho R.A., Miedema F., Schuitemaker H. Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission. J. Clin. Invest. 94:(5):1994;2060-2067.
69. Verhoef K., Sanders R.W., Fontaine V., Kitajima S., Berkhout B. Evolution of the human immunodeficiency virus type 1 long terminal repeat promoter by conversion of an NF-kappaB enhancer element into a GABP binding site. J. Virol. 73:(2):1999;1331-1340.
70. Weiss A., Wiskocil R.L., Stobo J.D. The role of T3 surface molecules in the activation of human T cells a two-stimulus requirement for IL 2 production reflects events occurring at a pre-translational level . J. Immunol. 133:(1):1984;123-128.
71. Wellman M.L., Krakowka S., Jacobs R.M., Kociba G.J. A macrophage-monocyte cell line from a dog with malignant histiocytosis. In Vitro Cell. Dev. Biol. 24:(3):1988;223-229.
72. Willey R.L., Smith D.H., Lasky L.A., Theodore T.S., Earl P.L., Moss B., Capon D.J., Martin M.A. In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity. J. Virol. 62:(1):1988;139-147.
73. Wu L., Paxton W.A., Kassam N., Ruffing N., Rottman J.B., Sullivan N., Choe H., Sodroski J., Newman W., Koup R.A., Mackay C.R. CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro. J. Exp. Med. 185:(9):1997;1681-1691.
74. Xiao L., Owen S.M., Goldman I., Lal A.A., Dejong J.J., Goudsmit J., Lal R.B. CCR5 coreceptor usage of non-syncytium-inducing primary HIV-1 is independent of phylogenetically distinct global HIV-1 isolates delineation of consensus motif in the V3 domain that predicts CCR-5 usage . Virology. 240:(1):1998;83-92.
75. Zhang D.E., Hetherington C.J., Chen H.M., Tenen D.G. The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor. Mol. Cell. Biol. 14:(1):1994;373-381.