Interaction between CCAAT/enhancer binding protein and cyclic amp response element binding protein 1 regulates human immunodeficiency virus type 1 transcription in cells of the monocyte/macrophage lineage

Journal of Virology

Volumn 75, Issue 4, 2001, Pages 1842-1856

  Ross, H L ^a   Nonnemacher, M R ^a   Hogan, T H ^a   Quiterio, S J ^a   Henderson, A ^a   McAllister, J J ^a   Krebs, F C ^a   Wigdahl, B ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIMER; INTERLEUKIN 6;

ARTICLE; BINDING SITE; CELL LINEAGE; CELL STRAIN U937; DIMERIZATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; MACROPHAGE; MONOCYTE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; VIRUS TRANSCRIPTION;

BINDING SITES; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIMERIZATION; DNA FOOTPRINTING; GENE EXPRESSION REGULATION, VIRAL; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; MACROPHAGES; MONOCYTES; MUTAGENESIS, SITE-DIRECTED; PLASMIDS; PROTEIN BINDING; TRANSCRIPTION, GENETIC; VARIATION (GENETICS);

EID: 0035135252     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.4.1842-1856.2001     Document Type: Article

References (44)

1. Human cell lines U-937, THP-1 and Mono Mac 6 represent relatively immature cells of the monocyte-macrophage cell lineage
2. A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family
3. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
4. Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein
5. Identification and characterization of a novel transcriptional activation domain in the CREB-binding protein
6. C/EBP-related protein 2 confers lipopolysaccharide-inducible expression of interleukin 6 and monocyte chemoattractant protein 1 to a lymphoblastic cell line
7. Improved chemiluminescent western blotting procedure
8. "Western blotting": Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
9. Molecular cloning of a transcription factor, AGP/EBP, that belongs to members of the C/EBP family
10. Phosphorylated CREB binds specifically to the nuclear protein CBP
11. Characterization of monoclonal antibodies raised against p300: Both p300 and CBP are present in intracellular TBP complexes
12. LAP, a novel member of the C/EBP gene family, encodes a liver-enriched transcriptional activator protein
13. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
14. Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus
15. Chemiluminescence detection of proteins from single cells
16. Constitutive monocyterestricted activity of NF-M, a nuclear factor that binds to a C/EBP motif
17. CCAAT/enhancer binding protein (C/EBP) sites are required for HIV-1 replication in primary macrophages but not CD4(+) T cells
18. C/EBP activators are required for HIV-1 replication and proviral induction in monocytic cell lines
19. C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes
20. Adaptor-mediated recruitment of RNA polymerase II to a signal-dependent activator
21. A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6
22. Neuroglial ATF/CREB factors interact with the human immunodeficiency virus type 1 long terminal repeat
23. Human immunodeficiency virus type 1 long terminal repeat quasispecies differ in basal transcription and nuclear factor recruitment in human glial cells and lymphocytes
24. HIV-associated neurologic dysfunction
25. Nuclear protein CBP is a coactivator for the transcription factor CREB
26. Isolation of a recombinant copy of the gene encoding C/EBP
27. Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8
28. Sequencing end-labeled DNA with base-specific chemical cleavages
29. Interaction and functional collaboration of p300 and C/EBPβ
30. Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6
31. CCAAT enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials
32. C/EBP beta regulation of the tumor necrosis factor alpha gene
33. The alpha-isoform of the CCAAT/enhancer-binding protein is required for mediating cAMP responsiveness of the phosphoenolpyruvate carboxykinase promoter in hepatoma cells
34. Chemiluminescent substrates increase sensitivity of antigen detection in western blots
35. ATF-2 and C/EBPalpha can form a heterodimeric DNA binding complex in vitro. Functional implications for transcriptional regulation
36. Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-κB
37. Transcription factor C/EBPalpha: Novel sites of expression and cloning of the human gene
38. Targeted disruption of the NF-IL6 gene discloses its essential role in bacteria killing and tumor cytotoxicity by macrophages
39. NF-IL6-mediated transcriptional activation of the long terminal repeat of the human immunodeficiency virus type 1
40. Molecular cloning of two C/EBP-related proteins that bind to the promoter and the enhancer of the alpha 1-fetoprotein gene. Further analysis of C/EBP beta and C/EBP gamma
41. C/ATF, a member of the activating transcription factor family of DNA-binding proteins, dimerizes with CAAT/enhancer-binding proteins and directs their binding to cAMP response elements
42. A family of C/EBP-related proteins capable of forming covalently linked leucine zipper dimers in vitro
43. Alterations in binding characteristics of the human immunodeficiency virus enhancer factor
44. CCAAT/enhancer binding protein epsilon is preferentially up-regulated during granulocytic differentiation and its functional versatility is determined by alternative use of promoters and differential splicing