HIV-1 LTR DNA sequence variation in brain-derived isolates

Journal of NeuroVirology

Volumn 3, Issue 5, 1997, Pages

  Corboy, John R ^a   Garl, Pamela J ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

AIDS dementia complex; Brain; HIV 1; LTR; Transcription factor binding sites; Viral tissue tropism

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR; VIRUS DNA;

ARTICLE; BINDING SITE; BLOOD; BRAIN; BRAIN INFECTION; CASE REPORT; CENTRAL NERVOUS SYSTEM; DNA POLYMORPHISM; DNA SEQUENCE; ENVELOPE GENE; GRAY MATTER; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; LONG TERMINAL REPEAT; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; WHITE MATTER;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030725210     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289709030747     Document Type: Article

References (75)

1. Achim CL, Wang R, Miners DL, Wiley CA (1994). Brain viral burden in HIV infection. J Neurolpathol Exp Neurol 53: 284-294.
2. Ait-Khaled M, McLaughlin JE, Johnson MA, Emery VC (1995). Distinct HIV-1 long terminal repeat quasispecies present in nervous tissues compared to that in lung, blood and lymphoid tissues of an AIDS patient. AIDS 9: 675-683.
3. Anand R, Reed C, Forlenza S, Siegal F, Cheung T, Moore J (1987). Non-cytocidal natural variants of human immunodeficiency virus isolated from AIDS patients with neurological disorders. Lancet 2: 234-238.
4. Atwood WJ, Berger JR, Kaderman R, Tornatore CS, Major EO (1993). Human immunodeficiency virus type 1 infection in the brain. Clin Microbiol Rev 6: 339-366.
5. Bagasra O, Lavi E, Bobroski L, Khalili K, Pestaner JP, Tawadros R, Pomerantz RJ (1996). Cellular reservoirs of HIV-1 in the central nervous system of HIV-1-infected-individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry. AIDS 10(6): 573-585.
6. Ball JE, Holmes EC, Whitwell H, Desselberger U (1994). Genomic variation of human immunodeficiency virus type 1 (HIV-1): molecular analyses of HIV-1 in sequential blood samples and various organs obtained at autopsy. J Gen Virol 75: 867-879.
7. Böni J, Emmerich BS, Leib SL, Wiestler OD, Schupbach J, Kleihus P (1993). PCR identification of HIV-1 DNA sequences in brain tissue of patients with AIDS encephalopathy. Neurology 43: 1813-1817.
8. Boyd MT, Simpson GR, Cann AJ, Johnson MA, Weiss RA (1993). A single amino acid substitution in the V1 loop of human immunodeficiency virus type 1 gp120 alters cellular tropism. J Virol 67: 3649-3652.
9. Brüstle O, Spiegel H, Leib SL, Finn T, Stein H, Kleihues P, Wiestler OD (1992). Distribution of human immunodeficiency virus (HIV) in the CNS of children with severe HIV encephalomyelopathy. Acta Neuropathol 84: 24-31.
10. Buzy JM, Lindstrom LM, Zink C, Clements JE (1995). HIV-1 in the developing CNS: developmental differences in gene expression. Virology 210: 361-371.
11. Cann AJ, Churcher MJ, Boyd M, O'Brien W, Zhae J, Chen ISY (1992). The region of the envelope gene of human immunodeficiency virus type 1 responsible for determination of cell tropism. J Virol 66: 305-309.
12. Canonne-Hergauz F, Aunis D, Schaffer E (1995). Interactions of the transcription factor AP-1 with the long terminal repeat of different human immunodeficiency virus type 1 strains in jurkat, glial, and neuronal cells. J Virol 69: 6634-6642.
13. Gelander D, Haseltine WA (1984). Tissue-specific transcription preference as a determinant of cell tropism and leukaemogenic potential of murine retroviruses. Nature 312: 159-162.
14. Cheng-Mayer E, Quiroga M, Tung JW, Dina D, Levy JA (1990). Viral determinants of human immunodeficiency virus type 1 T-cell or macrophage tropism, cytopathogenicity, and CD4 antigen modulation. J Virol 64: 4390-4398.
15. Cheng-Mayer D, Weiss C, Seto D, Levy JA (1989). Isolates of human immunodeficiency virus type 1 from the brain may constitute a special group of the AIDS virus. Proc Natl Acad Sci USA 86: 8575-8579.
16. Chesebro D, Wehrly K, Hishio J, Perryman S (1992). Macrophage-tropic human immunodeficiency virus isolates from different patients exhibit unusual V3 envelope sequence homogeneity in comparison with T-cell tropic isolates: Definition of critical amino acids involved in cell tropism. J Virol 66: 6547-6554.
17. Corboy JR, Buzy JM, Zink MC, Clements JE (1992). Expression directed from HIV long terminal repeats in the central nervous system of transgenic mice. Science, 258: 1804-1808.
18. Davis LE, Hjelle BL, Miller VE, Palmer DL, Llewellyn AL, Merlin TL, Young SA, Millis RG, Wachsman W, Wiley CA (1992). Early viral brain invasions in iatrogenic human immunodeficiency virus infection. Neurology 42: 1736-1739.
19. Delassus S, Cheynier R, Wain-Hobson S (1991). Evolution of human immunodeficiency virus type 1 nef and long terminal repeat sequences over 4 years in vivo and in vitro. J Virol 65: 225-231.
20. Epstein LG, Goudsmit J, Paul DA, Morrison SH, Connor EM, Oleske JM, Holland B (1987). Expression of human immunodeficiency virus in cerebrospinal fluid of children with progressive encephalopathy. Ann Neurol 21: 397-401.
21. Epstein LG, Kuiken C, Blumberg BM, Hartman S, Sharer LR, Clement M, Goudsmit J (1991). HIV-1 V3 domain variation in brain and spleen of children with AIDS: tissue-specific evolution within host-determined quasispecies. Virology 180: 583-590.
22. Estable MC, Bell B, Merzouki A, Montaner JSG, O'Shaughnessy MV, Sadowski IJ (1996). Human immunodeficiency virus type 1 long terminal repeat variants from 42 patients representing all stages of infection display a wide range of sequence polymorphism and transcription activity. J Virol 70: 4053-4062.
23. Gaynor R (1992). Cellular transcription factors involved in the regulation of HIV-1 gene expression. AIDS 6: 347-363.
24. Glass JD, Fedor H, Wesselingh SL, McArthur JC (1995). Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia. Ann Neurol 38: 755-762.
25. Golub El, Li G, Volsky DJ (1990). Differences in the basal activity of the long terminal repeat determine different replicative capacities of two closely related human immunodeficiency virus type 1 isolates. J Virol 64: 3654-3660.
26. Goodenow MM, Huet T, Saurin W, Kwok S, Sninsky J, Wain-Hobson S (1989). HIV-1 isolates are rapidly evolving quasispecies: evidence for viral mixtures and preferred nucleotide substitutions. J Acquir Immune Defic Syndr Hum Retrovirol 2: 344-352.
27. Groenink M, Andeweg AC, Fouchier AM, Broersen SM, Van Der Jagt RC, Schuitemaker H, De Goede REY, Rosch ML, Hisman HG, Tersmette M (1992). Phenotype-associated env gene variation among eight related human immunodeficiency virus type 1 clones: evidence for in vivo recombination and determinants of cytotropism outside the V3 domain. J Virol 66: 6175-6180.
28. Hwang SS, Boyle TJ, Lyerly HK, Cullen BR (1991). Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1. Science 253: 71-74.
29. Johnson RT, Glass JD, McArthur JC, Chesebro BW (1996). Quantitation of human immunodeficiency virus in brains of demented and nondemented patients with acquired immunodeficiency syndrome. Ann Neurol 39: 392-395.
30. Kim JYH, Gonzalez-Scarano F, Zeichner SL, Alwine JC (1993). Replication of type 1 human immunodeficiency viruses containing linker substitution mutations in the -201 to -130 region of the long terminal repeat. J Virol 67: 1658-1662.
31. Koenig S, Gendelman HE, Orenstein JM, Dal Canto MC, Pezeshkpour GH et al. (1986). Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 233: 1089-1093.
32. Koken SEC, VanWamel JLB, Goudsmit J, Borkhout B, Geelen JLMC (1992). Natural variants of the HIV-1 long terminal repeat: analysis of promoters with duplicated DNA regulatory motifs. Virology 191: 968-972.
33. Korber BTM, Kunstman KJ, Patterson BK, Fertado M, McEvilly MM, Levy R, Wolinsky AM (1994). Genetic differences between blood- and brain-derived viral sequences from human immunodeficiency virus type 1-infected patients: evidence of conserved elements in the V3 region of the envelope protien of brain-derived sequences. J Virol 68: 7467-7481.
34. Koyanagi Y, Miles S, Mitsuyasu TR, Merrill JE, Vinters HV, Chen ISY (1987). Dual infection of the cnetral nervous system by AIDS viruses with distinct cellular tropisms. Science 236: 819-822.
35. Krebs FC, Goodenow MM, Wigdahl B (1997). Neuroglial ATF/CREB factors interact with the human immunodeficiency virus type 1 long terminal repeat. J. Neurovirol, 3 (supp 1): S28-S32.
36. Kuiken CL, Goudsmit J, Weiller GF, Armstrong JS, Hartman S, Portegies P, Dekker J, Cornelissen M (1995). Differences in human immunodeficiency virus type 1 V3 sequences from patients with and without AIDS dementia complex. J Gen Virol 76: 175-180.
37. Kurth J, Buzy JM, Lindstrom L, Clements JE (1996). In vivo transcriptional regulation of the human immunodeficiency virus in the central nervous system in transgenic mice. J Virol 70: 7686-7694.
38. Lenz J, Colander D, Crowther RL, Patarca R, Perkins DW, Haseltine WA (1984). Determination of the leukaemogenicity of a murine retrovirus by sequences within the long terminal repeat. Nature 308: 467-470.
39. Li Y, Hui H, Burgess CJ, Price RW, Sharp PM, Hahn BH, Shaw GM (1992). Complete nucleotide sequence, genome organization, biological properties of human immunodeficiency virus type 1 in vivo: evidence for limited defectiveness and complementation. J Virol 66: 6587-6600.
40. Liu ZQ, Wood C, Levy JA, Cheng-Mayer C (1990). The viral envelope gene is involved in macrophage tropism of a human immunodeficiency virus type 1 strain isolated from brain tissue. J Virol 64: 6148-6153.
41. Lu Y, Touzjian N, Stenzel M, Dorfman T, Sodroski JG, Haseltine WA (1990). Identification of cis-acting repressive sequences within the negative regulatory element of human immunodeficiency virus type 1. J Virol 64: 5226-5229.
42. Masliah E, Achim CL, Ge N, DeTeresa R, Terry RD, Wiley CA (1992). Spectrum of human immunodeficiency virus-associated neocortical damage. Ann Neurol 32: 321-329.
43. McArthur JC, Seines OA, Glass JD, Hoover DR, Bacellar H (1994). HIV dementia: incidence and risk factors. In HIV, AIDS and the Brain. Price RW and Perry SW (eds). Raven Press, Ltd., New York. pp251-272
44. McNearney T, Hornickova Z, Templeton A, Birdwell A, Arens M, Markham R, Saah A, Taner L (1995). Nef and LTR sequence variation from sequentially derived human immunodeficiency virus type 1 isolates. Virology 208: 388-398.
45. Michael NL, D'Arcy L, Ehrenberg PK, Redfield RR (1994). Naturally occurring genotypes of the human immunodeficiency virus type 1 terminal repeat display a wide range of basal and tat-induced transcriptional activities. J Virol 68: 3163-3174.
46. Monken CE, Wu B, Srinivasan A (1995). High resolution analysis of HIV-1 quasispecies in the brain. AIDS 9: 345-349.
47. Myers G, Korber B, Hahn B, Jeang K-T, Pavlakis G, Meicors J, McCutchan F, Henderson L (eds). (1995). Human Retoviruses and AIDS 1995 Los Alamos National Laboratory, Theoretical Biology and Biophysics. Los Alamos, New Mexico.
48. Navia BA, Jordan BD, Price RW (1986). The AIDS dementia complex: I. clinical features. Ann Virol 19: 517-524.
49. Nuovo GJ, Gallery F, MacConnell P, Braun A (1994). In situ detection of PCR-amplified HIV-1 nuclei acids and tumor necrosis factor alpha RNA in the central nervous system. Am J Pathol 144: 659-666.
50. O'Brien WA, Koyanagi Y, Namazio A, Zhao J, Diagne A, Idler K, Zack JA, Chen ISY (1990). HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain. Nature 348: 69-73.
51. Orchard K, Perkins N, Chapman C, Harris J, Emery V, Goodwin G, Latchman D, Collins M (1990). A novel T-cell protein which recognizes a palindromic sequence in the negative regulatory element of the human immunodeficiency virus long terminal repeat. J Virol 64: 3234-3239.
52. Pang S, Vinters HV, Akashi T, O'Brien WA, Chen ISY (1991). HIV-1 env sequence variation in brain tissue patients with AIDS-related neurologic disease. J Acquir Immun Defic Syndr 4: 1082-1092.
53. Poliquin L, Bergeron D, Fortier J, Paquette Y, Bergeron R, Rassart E (1992). Determinants of thymotropism in Kaplan radiation leukemia virus and nucleotide sequence of its envelope region. J Virol 66: 5141-5146
54. Pomerantz RJ, Feinberg MB, Andino R, Baltimore D (1991). The long terminal repeat is not a major determinant of the cellular tropism of human immunodeficiency virus type 1. J Virol 65: 1041-1045.
55. Portis JL, Czub S, Garon CF, McAtee FJ (1990). Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat gag-pol sequences from nondefective friend murine leukemia virus. J Virol 64: 1648-1656.
56. Power C, McArthur JC, Johnson RT, Griffin DE, Glass JD, Perryman S, Chesebro (1994). Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences. J Virol 68: 4643-4649.
57. Resnick L, Berger JR, Shapshak P, Tourtelotte WW (1988). Early penetration of the blood brain barrier by HIV. Neurology 38: 9-14.
58. Rosen CA, Haseltine WA, Lenz J, Ruprecht R, Cloyd MW (1985). Tissue selectivity of murine leukemia virus infection is determined by long terminal repeat sequences. J Virol 55: 862-866.
59. Rosen CA, Sodroski JG, Haseltine (1985). The location of cis-acting regulatory sequences in the human T cell lymphotrophic virus type III long terminal repeat. Cell 41: 813-823.
60. Saito Y, Sharer LR, Epstein LG, Michaels J, Mintz M, Louder M, Golding K, Cvetkovich TA, Blumberg BM (1994). Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in post-mortem pediatric central nervous tissues. Neurology 44: 474-481.
61. Saitou N, Nei M (1987). The neighbor-joining method: a new method for reconstructing phylogenetic trees. Molec Biological Evolution 4: 406-425.
62. Sharer LR (1992). Pathology of HIV-1 infection of the central nervous system. A review. J Neuropathol Exp Neurol 51: 3-11.
63. Sharpless NE, O'Brien WA, Verdin E, Kufta CV, Chen ISY, Dubois-Dalcq M (1992). Human immunodeficiency virus type 1 tropism for brain microglial cells is determined by a region of the env glycoprotein that also controls macrophage tropism. J Virol 66: 2588-2593.2
64. Shimizu NS, Shimizu NG, Takeuchi Y, Hoshino H (1994). Isolation and characterization of human immunodeficiency virus type 1 variants infectious to brain-derived cells: detection of common point mutations in the V3 region of the env gene of the variants. J Virol 68: 6130-6135.
65. Shioda T, Levy JA, Cheng-Mayer C (1991). Macrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene. Nature 349: 167-169.
66. Small JA, Bieberich C, Ghotbi A, Hess J, Scangos GA, Clements JE (1989). The visna virus long terminal repeat directs expression of a reporter gene in activated macrophages, lymphocytes, and the central nervous systems of transgenic mice. J Virol 63: 1891-1896.
67. Takahashi K, Wesselingh SL, Griffin DE, McArthur JC, Johnson RT, Glass JD (1996). Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry. Ann Neurol 39: 705-711.
68. Tillmann M, Krebs FC, Wessner R, Pomeroy SM, Goodenow MM, Wigdahl B (1994). Neuroglial-specific factors and the regulation of retrovirus transcription. Advances in Neuroimmunology 4: 305-318.
69. Tornatore C, Chandra R, Berger JR, Major EO (1994). HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurology 44: 481-487.
70. Watkins BA, Dorn HH, Kelly WB, Armstrong RC, Potts BJ, Michaels F, Kufta CV, Dubois-Dalcq M (1990). Specific tropism of HIV-1 for microglial cells in primary human brain cultures. Science 249: 549-553.
71. Weiser B, Peress N, La Neve D, Eilbott DJ, Seidman R, Burger H (1990). Human immunodeficiency virus type 1 expression in the central nervous system correlates directly with extent of disease. Proc Natl Acad Sci USA 87: 3997-4001.
72. Wiley CA, Baldwin M, Achim CL (1996). Expression of HIV regulatory and structural mRNA in the central nervous system. AIDS 10: 843-847.
73. Wiley CA, Schrier RD, Nelson JA, Lamport PW, Oldstone MBA (1986). Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Pro Natl Acad Sci USA 83: 7089-7093.
74. Yuen PH, Tzeng E, Knupp C, Wong PKY (1986). The neurovirulent determinants of ts1, a paralytogenic mutant of moloney murine leukemia virus TB, are localized in at least two functionally distinct regions of the genome. J Virol 59: 59-65.
75. Zeichner SL, Hirka G, Andrews PW, Alwine JC (1992). Differentiation-dependent human immunodeficiency virus long terminal repeat regulatory elements active in human terarocarcinoma cells. J Virol 66: 2268-2273.