Analysis of the HIV-1 LTR NF-κB-proximal Sp site III: Evidence for cell type-specific gene regulation and viral replication

Virology

Volumn 274, Issue 2, 2000, Pages 262-277

  McAllister, J J ^a   Phillips, D ^a   Millhouse, S ^a   Conner, J ^a   Hogan, T ^a   Ross, H L ^a   Wigdahl, B ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; CIS ACTING ELEMENT; GLYCOPROTEIN GP 120; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR SP3; VPR PROTEIN;

ARTICLE; CELL SPECIFICITY; CELL TYPE; GENE EXPRESSION REGULATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; MONOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS REPLICATION;

EID: 0034284908     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2000.0476     Document Type: Article

References (57)

1. Distinct HIV-1 long terminal repeat quasispecies present in nervous tissues compared to that in lung, blood and lymphoid tissues of an AIDS patient
2. Trans-activator gene of human T-lymphotropic virus type III (HTLV-III)
3. Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
4. Functional roles for the TATA promoter and enhancers in basal and Tat-induced expression of the human immunodeficiency virus type 1 long terminal repeat
5. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
6. HIV coreceptors, cell tropism and inhibition by chemokine receptor ligands
7. Human immunodeficiency virus type 1 variants with increased replicative capacity develop during the asymptomatic stage before disease progression
8. Expression directed from HIV long terminal repeats in the central nervous system of transgenic mice
9. HIV-1 LTR DNA sequence variation in brain-derived isolates
10. Regulation of human immunodeficiency virus replication
11. Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays
12. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
13. Human immunodeficiency virus type 1 long terminal repeat variants from 42 patients representing all stages of infection display a wide range of sequence polymorphism and transcription activity
14. Evolution of mutation rate and virulence among human retroviruses
15. A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: Application to components of the Escherichia coli lactose operon regulatory system
16. Cloning by recognition site screening of two novel GT box binding proteins: A family of Sp1 related genes
17. Sp1-mediated transcriptional activation is repressed by Sp3
18. Role of SP1-binding domains in in vivo transcriptional regulation of the human immunodeficiency virus type 1 long terminal repeat
19. Expanding the TRANSFAC database towards an expert system of regulatory molecular mechanisms
20. CCAAT/enhancer binding protein (C/EBP) sites are required for HIV-1 replication in primary macrophages but not CD4(+) T cells
21. HIV-1 envelope determinants for cell tropism and chemokine receptor use
22. Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1
23. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase
24. O-glycosylation of eukaryotic transcription factors: Implications for mechanisms of transcriptional regulation
25. George Otto Gey (1899-1970). The HeLa cell and a reappraisal of its origin
26. Activation of the AIDS retrovirus promoter by the cellular transcription factor, Sp1
27. Control of RNA initiation and elongation at the HIV-1 promoter
28. Sp1-dependent activation of a synthetic promoter by human immunodeficiency virus type 1 Tat protein
29. Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription
30. V3-independent determinants of macrophage tropism in a primary human immunodeficiency virus type 1 isolate
31. Cloning of GT box-binding proteins: A novel Sp1 multigene family regulating T-cell receptor gene expression
32. Activity of human immunodeficiency virus type 1 promoter/TAR regions and tat1 genes derived from individuals with different rates of disease progression
33. Human immunodeficiency virus type 1 long terminal repeat quasispecies differ in basal transcription and nuclear factor recruitment in human glial cells and lymphocytes
34. Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: Identification of replication-competent and -defective viral genomes
35. Identification of cis-acting repressive sequences within the negative regulatory element of human immunodeficiency virus type 1
36. Intrahost human immunodeficiency virus type 1 evolution is related to length of the immunocompetent period
37. Different members of the Sp1 multigene family exert opposite transcriptional regulation of the long terminal repeat of HIV-1
38. Naturally occurring genotypes of the human immunodeficiency virus type 1 long terminal repeat display a wide range of basal and Tat-induced transcriptional activities
39. Sp1 and related factors fail to interact with the NF-kappaB-proximal G/C box in the LTR of a replication competent, brain-derived strain of HIV-1 (YU-2)
40. Induction of human malignant T-lymphoblastic cell lines MOLT-3 and jurkat by 12-O-tetradecanoylphorbol-13-acetate: Biochemical, physical, and morphological characterization
41. HIV-1 tropism for mononuclear phagocytes can be determined by regions of gp120 outside the CD4-binding domain
42. Rapid generation of sequence variation during primary HIV-1 infection
43. Variable role of the long terminal repeat Sp1-binding sites in human immunodeficiency virus replication in T lymphocytes
44. A cooperative interaction between NF-kappa B and Sp1 is required for HIV-1 enhancer activation
45. Neurode-generative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend murine leukemia virus
46. Contribution of NF-kappa B and Sp1 binding motifs to the replicative capacity of human immunodeficiency virus type 1: Distinct patterns of viral growth are determined by T-cell types
47. Suppression of HIV-1 transcription and replication by a Vpr mutant
48. Human immunodeficiency virus type 1 T-lymphotropic strains enter macrophages via a CD4- and CXCR4-mediated pathway: Replication is restricted at a postentry level
49. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: Progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population
50. Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture
51. Macrophage and T cell-line tropisms of HIV-1 are determined by specific regions of the envelope gp120 gene
52. Determinants of entry cofactor utilization and tropism in a dualtropic human immunodeficiency virus type 1 primary isolate
53. Selective employment of chemokine receptors as human immunodeficiency virus type 1 coreceptors determined by individual amino acids within the envelope V3 loop
54. Establishment and characterization of a human histiocytic lymphoma cell line (U-937)
55. The Sp-family of transcription factors
56. Tropism for primary monocytes and for monocytoid cell lines are separate features of HIV-1 variants
57. Interaction of virion protein Vpr of human immunodeficiency virus type 1 with cellular transcription factor Sp1 and trans-activation of viral long terminal repeat