Mycobacteriurn tuberculosis virulence correlates with mitochondrial cytochrome c release in infected macrophages

Scandinavian Journal of Immunology

Volumn 58, Issue 4, 2003, Pages 419-427

  Abarca Rojano, E ^a   Rosas Medina, P ^b   Zamudio Cortez P ^b   Mondragon Flores R ^a   Sanchez Garcia F J ^a,c  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

^b INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

^c INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYTOCHROME C;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIAL TRANSLOCATION; BACTERIAL VIRULENCE; CELL ULTRASTRUCTURE; CORRELATION ANALYSIS; CYTOSOL; ENZYME RELEASE; HOST PATHOGEN INTERACTION; MACROPHAGE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; ANIMAL; ELECTRON MICROSCOPY; METABOLISM; MICROBIOLOGY; MITOCHONDRION; PATHOGENICITY; PATHOLOGY; ULTRASTRUCTURE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CYTOCHROME C GROUP; MACROPHAGES; MICE; MICROSCOPY, ELECTRON; MITOCHONDRIA; MYCOBACTERIUM TUBERCULOSIS;

EID: 0141593562     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2003.01318.x     Document Type: Article

References (48)

1. Bloom BR, Murray CJ. Tuberculosis: commentary on a re-emergent killer. Science 1992;257:1055-64.
2. Schlesinger LS. Entry of Mycobacterium tuberculosis into mononuclear phagocytes. Curr Top Microbiol Immunol 1996;215:71-96.
3. Klinger K, Tchou-Wong K-M, Brandii O et al. Effects of mycobacteria on regulation of apoptosis in mononuclear phagocytes. Infect Immun 1997;65:5272-8.
4. Molloy A, Laochumroonvorapong P, Kaplan G. Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guerin. J Exp Med 1994;180:1499-509.
5. Rojas M, Barrera LF, Puzo G, García LF. Differential induction of apoptosis by virulent Mycobacterium tuberculosis in resistant and susceptible murine macrophages. Role of nitric oxide and mycobacterial products. J Immunol 1997;159:1352-61.
6. Rojas M, Olivier M, Gros P, Barrera LF, García LF. TNF-α and IL-10 modulate the induction of apoptosis by virulent Mycobacterium tuberculosis in murine macrophages. J Immunol 1999;162:6122-31.
7. Arai T, Hiromatsu K, Nishimura H et al. Endogenous interleukin 10 prevents apoptosis in macrophages during Salmonella infection. Biochem Biophys Res Commun 1995;213:600-7.
8. Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science 1997;275:1132-6.
9. Naoufal Z, Susin SA, Marchetti P et al. Mitochondrial control of nuclear apoptosis. J Exp Med 1996;183:1533-44.
10. Vander Heiden MG, Chandel NS, Schumacker PT, Thompson CB. Bclx, regulates the membrane potential and Volume homeostasis of mitochondria. Cell 1997;91:627-37.
11. Xuesong LN, Caryn K, Jie Y, Ronald J, Xiandong W. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 1996;86:147-57.
12. Yang J, Xuesong LX, Bhalla K et al. Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked. Science 1997;275:1129-32.
13. Li P, Nijhawan D, Budihardjo I et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-89.
14. Hockenbery D, Nuñez G, Milliman C, Schreiber RD, Korsmeyer JS. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990;348:334-6.
15. Budihardjo I, Oliver H, Lutter M, Luo X, Wang X. Biochemical pathways of caspase activation during apoptosis. Annu Rev Dev Biol 1999;15:269-90.
16. Luo X, Budihardjo I, Zou H, Slaughter C, Wang X. Bid, a Bcl-2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998;94:481-90.
17. Chakraborti T, Das S. Oxidant, mitochondria and calcium: an overview. Cell Signal 1999;11:77-85.
18. Green DR, Reed JC. Mitochondria and apoptosis. Science 1998;281:1309-12.
19. Li H, Zhu H, Chi-jie-Xu Z, Yuan J. Cleavage of Bid by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998;94:491-501.
20. Rathmell JC, Thompson CB. The central effectors of death in the immune system. Annu Rev Immunol 1999;17:781-828.
21. Zou H, Henzel J, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to Caenorhabditis elegans CED-4, participates in cytochrome c-dependent activation of Caspase-3. Cell 1997;90:405-13.
22. Nagahara Y, Ikekita M, Shinomiya T. Immunosuppressant FTY720 induces apoptosis by direct induction of permeability transition and release of cytochrome c from mitochondria. J Immunol 2000;165:3250-9.
23. Jendrossek V, Grassmé H, Mueller I, Lang F, Gulbins E. Pseudomonas-aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases. Infect Immun 2001;69:2675-83.
24. Mehta PK, King CH, White EH, Murtagh JJ, Quinn FD. Comparison of in vitro models for the study of Mycobacterium tuberculosis invasion and intracellular replication. Infect Immun 1996;64:2673-9.
25. Paul S, Laochumroonvorapong P, Kaplan G. Comparable growth of virulent and avirulent Mycobacterium tuberculosis in human macrophages in vitro. J Infect Dis 1996;174:105-12.
26. Silver RF, Li Q, Ellner JJ. Expression of virulence of Mycobacterium tuberculosis within human monocytes: virulence correlates with intracellular growth and induction of tumor necrosis factor alpha but not with evasion of lymphocyte dependent monocyte effector functions. Infect Immun 1998;66:1190-9.
27. Zhang M, Gong J, Lin Y, Barnes PF. Growth of virulent and avirulent Mycobacterium tuberculosis strains in human macrophages. Infect Immun 1998;66:794-9.
28. Millard I, Degrave E, Mariane P, Gala J-L. Detection of intracellular antigens by flow cytometry: comparison of two chemical methods and microwave heating. Clin Chem 1998;44:2320-34.
29. Vayssiére JL, Larcher JC, Berthelot F, Benlot C, Gros F, Croizat B. Effects on mitochondrial metabolism of CCA, one inducer of neuroblastoma differentiation. Biochem Biophys Res Commun 1986;140:789-96.
30. Kroemer G, Reed JC. Mitochondrial control of cell death. Nat Med 2000;6:513-9.
31. Petit PX, Lecouer H, Zorn E, Douguet C, Mignotte B, Gougeon M-L. Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J Cell Biol 1995;130:157-67.
32. Vayssière J-L, Petit PX, Risler Y, Mignotte B. Commitment to apoptosis is associated with changes in mitochondrial biogenesis and activity in cell lines conditionally immortalized with simian virus 40. Proc Natl Acad Sci USA 1994;91:11752-6.
33. Zanzami N, Susin SA, Marchetti M, Hirsch T, Castedo M, Kroemer G. Mitochondrial control of nucler apoptosis. J Exp Med 1996;183:1533-44.
34. Bossy-Wetzel E, Newmeyer DD, Green DR. Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrahe depolarization. EMBO J 1998;17:37-49.
35. Waterhouse NJ, Goldestein JC, Von Ahsen O, Schuler M, Newmeyer DD, Green DR. Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J Cell Biol 2001;16:319-28.
36. Beltrán B, Mathur A, Duchen MR, Rusalimsky JD, Moncada S. The effect of nitric oxide on cell respiration: a key to understanding its role in cell survival or death. Proc Natl Acad Sci USA 2000;97:14602-7.
37. Boyer PD. A model for conformational coupling of membrane potential and proton translocation to ATP synthesis and active transport. FEBS Lett 1975;58:1-6.
38. Mitchell P. Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism. Nature 1961;161:144-8.
39. Susin AS, Lorenzo KH, Zamzami N et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 1999;392:442-5.
40. Flesh IEAI, Kaufmann SHE. Mechanisms involved in mycobacterial growth inhibition by interferon-activated bone marrow macrophages: role of reactive nitrogen intermediates produced by activated murine macrophages. J Exp Med 1991;59:3213-8.
41. Brightbill HD, Libarty DH, Krutzik SR et al. Host defense mechanism triggered by microbial lipoproteins through toll-like receptors. Science 1999;285:732-6.
42. Pacheco-García U, Legorreta-Herrera M, Herná ndez-Rodríguez C, Sánchez-García FJ. Multiple Mycobacterium microti- derived lipids stimulate iNOS gene expression in the J774 murine macrophage cell line. Scand J Immunol 2002;56:52-8.
43. Roach TI, Barton C, Chatterjee D, Liew FY, Blackwell JM. Opposing effects of interferon-g on iNOS and interleukin-10 expression in lipopolisaccharide- and mycobacterial lipoarabinomannan-stimulated macrophages. Immunol 1995;85:106-10.
44. Chan J, Xing Y, Magliozzo RS, Bloom BR. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J Exp Med 1992;175:1111-22.
45. Brown GC, Cooper CE. Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase. FEBS Lett 1994;356:295-8.
46. Cleeter MW, Cooper JM, Darley-Usmar VM, Moncada S, Schapira AH. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiration chain, by nitric oxide. Implications for neurodegenerative diseases. FEBS Lett 1994;345:50-4.
47. Ragno S, Estrada-G I, Butler R, Colston MJ. Regulation of macrophage gene expression by Mycobacterium tuberculosis, down regulation of mitochondrial cytochrome c oxidase. Infect Immun 1998; 66:3952-8.
48. Blaskstone NW, Green DR. The evolution of a mechanism of cell suicide. Bioessays 1999;21:84-8.