Comparable growth of virulent and avirulent Mycobacterium tuberculosis in human macrophages in vitro

Journal of Infectious Diseases

Volumn 174, Issue 1, 1996, Pages 105-112

  Paul, Simon ^a   Laochumroonvorapong, Pairote ^a   Kaplan, Gilla ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; COLONY FORMING UNIT; CONTROLLED STUDY; ELECTRON MICROSCOPY; HOST CELL; HUMAN; HUMAN CELL; MACROPHAGE; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SPECIES DIFFERENCE;

EID: 0030054809     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/174.1.105     Document Type: Article

References (20)

1. Rich AR. The pathogenesis of tuberculosis. 2nd ed. Springfield, IL: Charles C Thomas, 1951:62-3.
2. Chan J, Xing Y, Magliozzo RS, Bloom DR. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J Exp Med 1992;175:1111-22.
3. Bermudez LE, Young LS. Oxidative and non-oxidative intracellular killing of Mycobacterium avium complex. Microb Pathog 1989;7:289-98.
4. Nibbering PH, Yoshida SI, van den Barselaar MT, van Furth R. Bacteriostatic activity of BCG/PPD-activated macrophages against Mycobacterium foruitum does not involve reactive nitrogen or oxygen intermediates. Scand J Immunol 1995;40:187-94.
5. Appelberg R, Orme IM. Effector mechanisms involved in cytokine-mediated bacteriostasis of Mycobacterium avium infections in murine macrophages. Immunology 1995;80:352-9.
6. Steenken WJ, Gardner LU. History of H37 strain of tubercle bacillus. Am Rev Tuberc 1946;54:62-6.
7. Dunn PL, North RJ. Virulence ranking of some Mycobacterium tuberculosis and Mycobacterium bovis strains according to their ability to multiply in the lungs, induce lung pathology, and cause mortality in mice. Infect Immun 1995;63:3428-37.
8. North RJ, Izzo AA. Mycobacterial virulence. Virulent strains of Mycobacterium tuberculosis have faster in vivo doubling times and are better equipped to resist growth-inhibiting functions of macrophages in the presence and absence of specific immunity. J Exp Med 1993;177:1723-33.
9. Falcone V, Bassey EB, Toniolo A, Conaldi PG, Collins FM. Differential release of tumor necrosis factor-alpha from murine peritoneal macrophages stimulated with virulent and avirulent species of mycobacteria. FEMS Immunol Med Microbiol 1995;8:225-32.
10. Boyum A. Separation of leukocytes. Scand J Clin Invest 1968;21(suppl 97):77-90.
11. Douvas GS, Berger EM, Repine JE, Crowle AJ. Natural mycobacteriostatic activity in human monocyte-derived adherent cells. Am Rev Respir Dis 1986;134:44-8.
12. Larson CL, Wicht WC. Infection of mice with Mycobacterium tuberculosis, strain H37Ra. Am Rev Respir Dis 1964;90:742-8.
13. Alsaadi A, Smith DW. The fate of virulent and attenuated mycobacteria in guinea pigs infected by the respiratory route. Am Rev Respir Dis 1973;107:1041-6.
14. Dubos RJ. Properties and structures of tubercle bacilli concerned in their pathogenicity. Symp Soc Gen Microbiol 1955;5:103-25.
15. Mackaness GB, Smith N, Wells AQ. The growth of intracellular tubercle bacilli in relation to their virulence. Am Rev Tuberc 1954;69:479-94.
16. Hsu US. The fate of Mycobacterium tuberculosis within macrophages of guinea pigs. Am Rev Respir Dis 1971;103:607-11.
17. McDonough KA, Kress Y. Cytotoxicity for lung epithelial cells is a virulence-associated phenotype of Mycobacterium tuberculosis. Infect Immun 1995;63:4802-11.
18. Schneemann M, Schoedon G, Hofer S, Blau N, Guerrero L, Schaffner A. Nitric oxide synthase is not a constituent of the antimicrobial armature of human mononuclear phagocytes. J Infect Dis 1993;167:1358-63.
19. Jackett PS, Aber VR, Lowrie DB. Virulence and resistance to superoxide, low pH, and hydrogen peroxide among strains of Mycobacterium tuberculosis. J Gen Microbiol 1978;104:37-45.
20. Molloy A, Laochumroonvorapong P, Kaplan G. Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guérin. J Exp Med 1994;180:1499-509.