Pseudomonas aeruginosa-induced apoptosis involves mitochondria and stress-activated protein kinases

Infection and Immunity

Volumn 69, Issue 4, 2001, Pages 2675-2683

  Jendrossek, V ^a   Grassme H ^a   Mueller, I ^a   Lang, F ^a   Gulbins, E ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; FAS ANTIGEN; JANUS KINASE; PROTEIN KINASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL INTERACTION; CONJUNCTIVA EPITHELIUM; CONTROLLED STUDY; CYSTIC FIBROSIS; DEPOLARIZATION; ENZYME ACTIVATION; ENZYME SYNTHESIS; EPITHELIUM CELL; IMMUNE DEFICIENCY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; STRESS;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; BACTERIAL PROTEINS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENZYME ACTIVATION; FAS LIGAND PROTEIN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; PSEUDOMONAS AERUGINOSA; REACTIVE OXYGEN SPECIES;

EID: 0035086284     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.4.2675-2683.2001     Document Type: Article

References (41)

1. Death receptors: Signaling and modulation
2. Stress signals for apoptosis: Ceramide and c-Jun kinase
3. A bacterial invasin induces macrophage apoptosis by binding directly to ICE
4. Pili binding to asialo-GM1 on epithelial cells can mediate cytotoxicity or bacterial internalization by Pseudomonas aeruginosa
5. ExoT of cytotoxic Pseudomonas aeruginosa prevents uptake by corneal epithelial cells
6. Host cell death due to enteropathogenic Escherichia coli has features of apoptosis
7. Pathogenic strategies of bacteria
8. Pseudomonas aeruginosa invasion and cytotoxicity are independent events, both of which involve protein tyrosine kinase activity
9. ExoU expression by Pseudomonas aeruginosa correlates with acute cytotoxicity and epithelial injury
10. Exploitation of mammalian host cell functions by bacterial pathogens
11. Pseudomonas aeruginosa invades corneal epithelial cells during experimental infection
12. Host defense to Pseudomonas aeruginosa requires CD95/CD95 ligand interactions on epithelial cells
13. Mitochondria and apoptosis
14. FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway
15. Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages
16. Pseudomonas aeruginosa induces type-III-secretion-mediated apoptosis of macrophages and epithelial cells
17. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
18. Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB
19. Adherence to and penetration of human intestinal Caco-2 epithelial cell monolayers by Pseudomonas aeruginosa
20. Triggering the ExoS regulon of Pseudomonas aeruginosa: A GFP-reporter analysis of exoenzyme (Exo) S, ExoT and ExoU synthesis
21. Translocatlon of SAPK/JNK to mitochondria and interaction with Bcl-xL in response to DNA-damage
22. The mitochondrial death/life regulator in apoptosis and necrosis
23. Involvement of caspase 3-activated DNase in internucleosomal DNA cleavage induced by diverse apoptotic stimuli
24. Internalization of Staphylococcus aureus by endothelial cells induces apoptosis
25. Yersinia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death
26. Caspases: The proteases of the apoptotic pathway
27. YopJ of Yersinia pseudo-tuberculosis is required for the inhibition of macrophage TNF-production and downregulation of the MAP kinase p38 and JNK
28. Apoptosis overview emphasizing the role of oxidative stress, DNA damage and signal-transduction pathways
29. Cystic fibrosis transmembrane conductance regulator is an epithelial cell receptor for clearance of Pseudomonas aeruginosa from the lung
30. Listeria monocytogenes induces apoptosis of infected hepatocytes
31. The yopJ locus is required for Yesinia-mediated inhibition of NFkappa B activation and cytokine expression: YopJ contains a eukaryotic SH-2 like domain that is essential for its repressive activity
32. Caspase: Executioner and undertaker of apoptosis
33. Caspases: Enemies within
34. Requirement of JNK for stress-induced activation of the cytochrome c mediated pathway
35. Biological effects of Pseudomonas aeruginosa type III secreted proteins on CHO cells
36. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
37. Exo Y, an adenylate cyclase secreted by the Pseudomonas aeruginosa type III system
38. Salmonella-induced apoptosis of infected macrophages results in presentation of a bacteria-encoded antigen after uptake by bystander dendritic cells
39. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
40. Shigella flexneri induces apoptosis in infected macrophages
41. IpaB mediates macrophage apoptosis induced by Shigella flexneri