메뉴 건너뛰기




Volumn 59, Issue 6, 1999, Pages 1347-1355

Monoclonal antibody to HER-2/neu receptor modulates repair of radiation- induced DNA damage and enhances radiosensitivity of human breast cancer cells overexpressing this oncogene

Author keywords

[No Author keywords available]

Indexed keywords

DNA; EPITOPE; MONOCLONAL ANTIBODY; RECEPTOR ANTIBODY;

EID: 0033559619     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (306)

References (55)
  • 1
    • 0028791012 scopus 로고
    • Effects of radiotherapy and surgery in early breast cancer
    • Early Breast Cancer Trialists' Collaborative Group. Effects of radiotherapy and surgery in early breast cancer. N. Engl. J. Med., 333: 1444-1455, 1195.
    • (1195) N. Engl. J. Med. , vol.333 , pp. 1444-1455
  • 2
    • 0029639928 scopus 로고
    • Recent advances in radiation oncology
    • Lichter, A. S., and Lawrence, T. S. Recent advances in radiation oncology. N. Engl. J. Med., 332: 371-379, 1995.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 371-379
    • Lichter, A.S.1    Lawrence, T.S.2
  • 3
    • 0028958705 scopus 로고
    • Growth factor modulation of p53-mediated growth arrest versus apoptosis
    • Canman, C. E., Gilmer, T. M., Coutts, S., and Kastan, M. Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev., 9: 600-611, 1995.
    • (1995) Genes Dev. , vol.9 , pp. 600-611
    • Canman, C.E.1    Gilmer, T.M.2    Coutts, S.3    Kastan, M.4
  • 5
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Washington DC
    • Slamon D. J., Clark, G. M., Wong, S. G., Levin, W., Ullrich, A., and McGuire, W. L. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (Washington DC), 235: 177-182, 1987.
    • (1987) Science , vol.235 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3    Levin, W.4    Ullrich, A.5    McGuire, W.L.6
  • 8
    • 0031034106 scopus 로고    scopus 로고
    • HER-2/neu signal transduction in human breast and ovarian cancer
    • Reese, D., and Slamon, D. HER-2/neu signal transduction in human breast and ovarian cancer. Stem Cells, 15: 1-8, 1997.
    • (1997) Stem Cells , vol.15 , pp. 1-8
    • Reese, D.1    Slamon, D.2
  • 9
    • 0023196582 scopus 로고
    • erbB2 is a potent oncogene when overexpressed in NIH-3T3 cells
    • Washington DC
    • DiFiore, P. P., Pierce, J. H., Kraus, M. H., Segatto, O., King, C. R., and Aaronson, S. A. erbB2 is a potent oncogene when overexpressed in NIH-3T3 cells. Science (Washington DC), 237: 178-181, 1987.
    • (1987) Science , vol.237 , pp. 178-181
    • DiFiore, P.P.1    Pierce, J.H.2    Kraus, M.H.3    Segatto, O.4    King, C.R.5    Aaronson, S.A.6
  • 10
    • 0023430930 scopus 로고
    • Increased expression of the putative growth factor receptor p185HER-2 causes transformation and tumorigenesis of NIH-3T3 cells
    • Hudziak, R. M., Schlessinger, J., and Ullrich, A. Increased expression of the putative growth factor receptor p185HER-2 causes transformation and tumorigenesis of NIH-3T3 cells. Proc. Natl. Acad. Sci. USA, 84: 7159-7163, 1987.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 7159-7163
    • Hudziak, R.M.1    Schlessinger, J.2    Ullrich, A.3
  • 11
    • 0026739541 scopus 로고
    • Transformation mediated by the human HER-2 gene independent of the epidermal growth factor receptor
    • Chazin, V., Kaleko, M. Miller, A., and Slamon, D. J. Transformation mediated by the human HER-2 gene independent of the epidermal growth factor receptor. Oncogene, 7: 1859-1865, 1992.
    • (1992) Oncogene , vol.7 , pp. 1859-1865
    • Chazin, V.1    Kaleko, M.2    Miller, A.3    Slamon, D.J.4
  • 16
    • 0030200381 scopus 로고    scopus 로고
    • Evaluation of HER-2 neu oncoprotein expression as a prognostic indicator of local recurrence in conservatively treated breast cancer: A case-control study
    • Haffty, B. G., Brown, F., Carter, D., and Flynn, S. Evaluation of HER-2 neu oncoprotein expression as a prognostic indicator of local recurrence in conservatively treated breast cancer: a case-control study. Int. J. Radiat. Oncol. Biol. Phys., 35: 751-757, 1996.
    • (1996) Int. J. Radiat. Oncol. Biol. Phys. , vol.35 , pp. 751-757
    • Haffty, B.G.1    Brown, F.2    Carter, D.3    Flynn, S.4
  • 17
    • 0024261027 scopus 로고
    • Efficacy of antibodies to epidermal growth factor receptor against KB carcinoma in nude mice
    • Bethesda
    • Aboud-Pirak, E., Hurwitz, E., Pirak, M. E., Bellot, F., Schlessinger, J., and Sela, M. Efficacy of antibodies to epidermal growth factor receptor against KB carcinoma in nude mice. J. Natl. Cancer Inst. (Bethesda). 80: 1605-1611, 1988.
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 1605-1611
    • Aboud-Pirak, E.1    Hurwitz, E.2    Pirak, M.E.3    Bellot, F.4    Schlessinger, J.5    Sela, M.6
  • 18
    • 0025052403 scopus 로고
    • Epidermal growth factor regulates the in vitro sensitivity of human ovarian carcinoma cells to cisplatin
    • Christen, R. D., Hom, D. K., Porter, D. C., Andrews, P. A., MacLeod, C. L., Hafstrom, L., and Howell, S. B. Epidermal growth factor regulates the in vitro sensitivity of human ovarian carcinoma cells to cisplatin. J. Clin. Invest., 86: 1632-1640, 1991.
    • (1991) J. Clin. Invest. , vol.86 , pp. 1632-1640
    • Christen, R.D.1    Hom, D.K.2    Porter, D.C.3    Andrews, P.A.4    MacLeod, C.L.5    Hafstrom, L.6    Howell, S.B.7
  • 19
    • 0024316128 scopus 로고
    • Enhancement of sensitivity of human squamous carcinoma cells to radiation by epidermal growth factor
    • Bethesda
    • Kwock, T. T., and Sutherland, R. M. Enhancement of sensitivity of human squamous carcinoma cells to radiation by epidermal growth factor. J. Natl. Cancer Inst. (Bethesda), 81: 1020-1024, 1989.
    • (1989) J. Natl. Cancer Inst. , vol.81 , pp. 1020-1024
    • Kwock, T.T.1    Sutherland, R.M.2
  • 20
    • 0027362521 scopus 로고
    • Oncogene-transformed NIH 3T3 cells display radiation resistance levels indicative of a signal transduction pathway leading to the radiation-resistant phenotype
    • Pirollo, K., Tong, Y., Villegas, Z., Chen, Y., and Chang, E. Oncogene-transformed NIH 3T3 cells display radiation resistance levels indicative of a signal transduction pathway leading to the radiation-resistant phenotype. Radiat. Res., 135: 234-243, 1993.
    • (1993) Radiat. Res. , vol.135 , pp. 234-243
    • Pirollo, K.1    Tong, Y.2    Villegas, Z.3    Chen, Y.4    Chang, E.5
  • 21
    • 0027929971 scopus 로고
    • Effect of epidermal growth factor on the growth and radiation sensitivity of human breast cancer cells in vitro
    • Wollman, R., Yahalom, J., Maxy, R., Pinto, J., and Fuks, Z. Effect of epidermal growth factor on the growth and radiation sensitivity of human breast cancer cells in vitro. Int. J. Radiat. Oncol. Biol. Phys., 30: 91-98, 1994.
    • (1994) Int. J. Radiat. Oncol. Biol. Phys. , vol.30 , pp. 91-98
    • Wollman, R.1    Yahalom, J.2    Maxy, R.3    Pinto, J.4    Fuks, Z.5
  • 22
    • 0028200221 scopus 로고
    • Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells
    • Pietras, R. J., Fendly, B. M., Chazin, V., Pegram, M. D., Howell, S. B., and Slamon, D. J. Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells. Oncogene, 9: 1829-1838, 1994.
    • (1994) Oncogene , vol.9 , pp. 1829-1838
    • Pietras, R.J.1    Fendly, B.M.2    Chazin, V.3    Pegram, M.D.4    Howell, S.B.5    Slamon, D.J.6
  • 23
    • 0025986825 scopus 로고
    • A monoclonal antibody against the c-crbB-2 protein enhances the cytotoxicity of cisdiamminedichloroplatinum against human breast and ovarian tumor cell lines
    • Hancock, M. C., Langton, B. C., Chan, T., Toy, P., Monahan, J., Mischak, R., and Shawver, L. K. A monoclonal antibody against the c-crbB-2 protein enhances the cytotoxicity of cisdiamminedichloroplatinum against human breast and ovarian tumor cell lines. Cancer Res., 51: 4575-4580, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 4575-4580
    • Hancock, M.C.1    Langton, B.C.2    Chan, T.3    Toy, P.4    Monahan, J.5    Mischak, R.6    Shawver, L.K.7
  • 24
    • 0023748941 scopus 로고
    • A Reduced rate of bulky DNA adduct removal is coincident with differentiation of human neuroblastoma cells induced by NGF
    • Jensen, L., and Linn, S. A Reduced rate of bulky DNA adduct removal is coincident with differentiation of human neuroblastoma cells induced by NGF. Mol. Cell. Biol., 8: 3964-3969, 1988.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3964-3969
    • Jensen, L.1    Linn, S.2
  • 25
    • 0026318356 scopus 로고
    • Participation of p53 protein in the cellular response to DNA damage
    • Kastan, M., Onyekwere, O., Sidransky, D., Vogelstein, B., and Craig, R. Participation of p53 protein in the cellular response to DNA damage Cancer Res., 51: 6304-6311, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 6304-6311
    • Kastan, M.1    Onyekwere, O.2    Sidransky, D.3    Vogelstein, B.4    Craig, R.5
  • 26
    • 0027258466 scopus 로고
    • Thymocyte apoptosis induced by p53-dependent and independent pathways
    • Lond.
    • Clarke, A., Purdie, C., Harrison, D., Morris, R., Bird, C., Hooper, M., and Wylie, A. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature (Lond.), 362: 849-852, 1993.
    • (1993) Nature , vol.362 , pp. 849-852
    • Clarke, A.1    Purdie, C.2    Harrison, D.3    Morris, R.4    Bird, C.5    Hooper, M.6    Wylie, A.7
  • 27
    • 0028919069 scopus 로고
    • Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage
    • Smith, M., Chen, I-T., Zhan, Q., O'Connor, P., and Fornace, A., Jr. Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage. Oncogene, 10: 1053-1059, 1995.
    • (1995) Oncogene , vol.10 , pp. 1053-1059
    • Smith, M.1    Chen, I.-T.2    Zhan, Q.3    O'Connor, P.4    Fornace A., Jr.5
  • 31
    • 0029664395 scopus 로고    scopus 로고
    • Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway
    • Liu, Y., Martindale, J., Gorospe, M., and Holbrook, N. Regulation of p21WAF1/CIP1 expression through mitogen-activated protein kinase signaling pathway. Cancer Res., 56: 31-35, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 31-35
    • Liu, Y.1    Martindale, J.2    Gorospe, M.3    Holbrook, N.4
  • 32
    • 0025318271 scopus 로고
    • Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product
    • Fendly, B. M., Winget, M., Hudziak, R., Lipari, M., Napier, M., and Ullrich, A. Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product. Cancer Res., 50: 1550-1558, 1990.
    • (1990) Cancer Res. , vol.50 , pp. 1550-1558
    • Fendly, B.M.1    Winget, M.2    Hudziak, R.3    Lipari, M.4    Napier, M.5    Ullrich, A.6
  • 34
    • 0029879442 scopus 로고    scopus 로고
    • Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of erbB2 as a critical component in mediating heregulin responsiveness
    • Lewis, G., Lofgren, J., McMurtrey, A., Nuijens, A., Fendly, B., Bauer, K., and Sliwkowski, M. Growth regulation of human breast and ovarian tumor cells by heregulin: evidence for the requirement of erbB2 as a critical component in mediating heregulin responsiveness. Cancer Res., 56: 1457-1465, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 1457-1465
    • Lewis, G.1    Lofgren, J.2    McMurtrey, A.3    Nuijens, A.4    Fendly, B.5    Bauer, K.6    Sliwkowski, M.7
  • 35
    • 0024443869 scopus 로고
    • Scheduled and unscheduled DNA synthesis in chick embryo liver following X-irradiation and treatment with DNA repair inhibitors in vivo
    • Stammberger, I., Schmahl, W., and Tempel, K. Scheduled and unscheduled DNA synthesis in chick embryo liver following X-irradiation and treatment with DNA repair inhibitors in vivo. Int. J. Radiat. Biol., 56: 325-333, 1989.
    • (1989) Int. J. Radiat. Biol. , vol.56 , pp. 325-333
    • Stammberger, I.1    Schmahl, W.2    Tempel, K.3
  • 36
    • 0017402672 scopus 로고
    • Detection of chemical carcinogens by unscheduled DNA synthesis in rat liver primary cell cultures
    • Williams, G. M. Detection of chemical carcinogens by unscheduled DNA synthesis in rat liver primary cell cultures. Cancer Res., 37: 1845-1851, 1977.
    • (1977) Cancer Res. , vol.37 , pp. 1845-1851
    • Williams, G.M.1
  • 37
    • 0030002545 scopus 로고    scopus 로고
    • Repair defect in p21WAF1/CIP1 -/-human cancer cells
    • McDonald, E. R., III, Wu, G. S., Waldman, T., and El-Deiry, W. S. Repair defect in p21WAF1/CIP1 -/-human cancer cells. Cancer Res., 56: 2250-2255, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 2250-2255
    • McDonald E.R. III1    Wu, G.S.2    Waldman, T.3    El-Deiry, W.S.4
  • 39
    • 0020793569 scopus 로고
    • A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
    • Feinberg, A. P., and Vogelstein, B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem., 132: 6-13, 1987.
    • (1987) Anal. Biochem. , vol.132 , pp. 6-13
    • Feinberg, A.P.1    Vogelstein, B.2
  • 40
    • 0030870295 scopus 로고    scopus 로고
    • The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells
    • Pegram, M. D., Finn, R. S., Arzoo, K., Beryt, M., Pietras, R. J., and Slamon, D. J. The effect of HER-2/neu overexpression on chemotherapeutic drug sensitivity in human breast and ovarian cancer cells. Oncogene, 15: 537-547, 1997.
    • (1997) Oncogene , vol.15 , pp. 537-547
    • Pegram, M.D.1    Finn, R.S.2    Arzoo, K.3    Beryt, M.4    Pietras, R.J.5    Slamon, D.J.6
  • 41
    • 0026585352 scopus 로고
    • DNA damage by drugs and radiation
    • Whitaker, S. J. DNA damage by drugs and radiation. Eur. J. Cancer. 28: 273-276, 1992.
    • (1992) Eur. J. Cancer. , vol.28 , pp. 273-276
    • Whitaker, S.J.1
  • 42
    • 0031550257 scopus 로고    scopus 로고
    • Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells
    • Pirollo, K. F., Hoo, Z., Rait, A., Ho, C. W., and Chang, E. H. Evidence supporting a signal transduction pathway leading to the radiation-resistant phenotype in human tumor cells. Biochem. Biophys. Res. Commun., 230: 196-201, 1997.
    • (1997) Biochem. Biophys. Res. Commun. , vol.230 , pp. 196-201
    • Pirollo, K.F.1    Hoo, Z.2    Rait, A.3    Ho, C.W.4    Chang, E.H.5
  • 43
    • 0029074748 scopus 로고
    • Irradiation induces WAF1 expression through a p53-independent pathway in KG-1 cells
    • Akashi, M., Hachiya, M., Osawa, Y., Spirin, K., and Suzuki, G. Irradiation induces WAF1 expression through a p53-independent pathway in KG-1 cells. J. Biol. Chem., 270: 19181-19187, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 19181-19187
    • Akashi, M.1    Hachiya, M.2    Osawa, Y.3    Spirin, K.4    Suzuki, G.5
  • 46
    • 0030850047 scopus 로고    scopus 로고
    • Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
    • Scully, R., Chen, J., Ochs, R. L., Keegan, K., Hoekstra, M., Feunteun, J., and Livingston, D. M. Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell. 90: 425-435, 1997.
    • (1997) Cell , vol.90 , pp. 425-435
    • Scully, R.1    Chen, J.2    Ochs, R.L.3    Keegan, K.4    Hoekstra, M.5    Feunteun, J.6    Livingston, D.M.7
  • 48
    • 0029928561 scopus 로고    scopus 로고
    • Apoptotic death of tumor cells correlates with chemosensitivity, independent of p53 or bcl-2
    • Wu, G. S., and El-Deiry, S. Apoptotic death of tumor cells correlates with chemosensitivity, independent of p53 or bcl-2. Clin. Cancer Res., 2: 623-633, 1996.
    • (1996) Clin. Cancer Res. , vol.2 , pp. 623-633
    • Wu, G.S.1    El-Deiry, S.2
  • 49
    • 0030800922 scopus 로고    scopus 로고
    • Mdm2: Keeping p53 under control
    • Piette, J., Neel, H., and Marechal, V. Mdm2: keeping p53 under control. Oncogene, 15: 1001-1010, 1997.
    • (1997) Oncogene , vol.15 , pp. 1001-1010
    • Piette, J.1    Neel, H.2    Marechal, V.3
  • 50
    • 0030860911 scopus 로고    scopus 로고
    • Repression of p53-mediated transcription by MDM2: A dual mechanism
    • Thut, C. J., Goodrich, J. A., and Tijan, R. Repression of p53-mediated transcription by MDM2: a dual mechanism. Genes Dev., 11: 1974-1986, 1997.
    • (1997) Genes Dev. , vol.11 , pp. 1974-1986
    • Thut, C.J.1    Goodrich, J.A.2    Tijan, R.3
  • 52
    • 0028796895 scopus 로고
    • NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells
    • Marte, B., Graus-Porta, D., Jeschke, M., Fabbro, D., Hynes, N., and Taverna, D. NDF/heregulin activates MAP kinase and p70/p85 S6 kinase during proliferation or differentiation of mammary epithelial cells. Oncogene, 10: 167-175, 1995.
    • (1995) Oncogene , vol.10 , pp. 167-175
    • Marte, B.1    Graus-Porta, D.2    Jeschke, M.3    Fabbro, D.4    Hynes, N.5    Taverna, D.6
  • 53
    • 0026174552 scopus 로고
    • Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth
    • Sarup, J. C., Johnson, R. M., King, K. L., Fendly, B. M., Lipari, M. T., Napier, M. A., Ullrich, A., and Shepard, H. M. Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth. Growth Regul., 1: 72-82, 1991.
    • (1991) Growth Regul. , vol.1 , pp. 72-82
    • Sarup, J.C.1    Johnson, R.M.2    King, K.L.3    Fendly, B.M.4    Lipari, M.T.5    Napier, M.A.6    Ullrich, A.7    Shepard, H.M.8
  • 54
    • 0028893444 scopus 로고
    • Single-chain antibody-mediated intracellular retention of erbB-2 impairs neu differentiation factor and epidermal growth factor signaling
    • Graus-Porta, D., Beerli, R., and Hynes, N. Single-chain antibody-mediated intracellular retention of erbB-2 impairs neu differentiation factor and epidermal growth factor signaling. Mol. Cell. Biol.. 15: 1182-1191, 1995.
    • (1995) Mol. Cell. Biol.. , vol.15 , pp. 1182-1191
    • Graus-Porta, D.1    Beerli, R.2    Hynes, N.3
  • 55
    • 0030044628 scopus 로고    scopus 로고
    • Enhancement of chemosensitivity by tyrphostin AG825 in high-p185neu expressing non-small cell lung carcinoma cells
    • Tsai, C-M., Levitzki, A., Wu, L-H., Chang, K-T., Cheng, C-C., Gazit, A., and Perng, R-P. Enhancement of chemosensitivity by tyrphostin AG825 in high-p185neu expressing non-small cell lung carcinoma cells. Cancer Res., 56: 1068-1074, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 1068-1074
    • Tsai, C.-M.1    Levitzki, A.2    Wu, L.-H.3    Chang, K.-T.4    Cheng, C.-C.5    Gazit, A.6    Perng, R.-P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.