Adoption of the transiently non-culturable state - A bacterial survival strategy?

Advances in Microbial Physiology

Volumn 47, Issue , 2003, Pages 65-129

  Mukamolova, Galina V ^a,b   Kaprelyants, Arseny S ^b   Kell, Douglas B ^a,c   Young, Michael ^a  

^a ABERYSTWYTH UNIVERSITY   (United Kingdom)

^b BACH INSTITUTE OF BIOCHEMISTRY   (Russian Federation)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; BACTERIAL GENETICS; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BACTERIUM CULTURE; CELL POPULATION; CELL STRUCTURE; NONHUMAN; PHYSIOLOGY; REVIEW; SOCIAL BEHAVIOR; STARVATION; STRESS;

BACTERIA (MICROORGANISMS);

EID: 0141560580     PISSN: 00652911     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-2911(03)47002-1     Document Type: Review

References (361)

1. Abel, C.B.L., Lindon, J.C., Noble, D., Rudd, B.A.M., Sidebottom, P.J. and Nicholson, J.K. (1999) Characterization of metabolites in intact Streptomyces citricolor culture supernatants using high-resolution nuclear magnetic resonance and directly coupled high-pressure liquid chromatography-nuclear magnetic resonance spectroscopy. Anal. Biochem. 270, 220-230.
2. Allen, J.K., Davey, H.M., Broadhurst, D., Heald, J.K., Rowland, J.J., Oliver, S.G. and Kell, D.B. (2002) Metabolic footprinting: a high-throughput, high-information approach to cellular characterisation and functional genomics. Nature Biotechnol., doi: 10.1038/nbt 823.
3. Almiron, M., Link, A.J., Furlong, D. and Kolter, R. (1992) A novel DNA-binding protein with regulatory and protective roles in starved Escherichia coli. Genes Dev. 6, 2646-2654.
4. Amann, R.I., Ludwig, W. and Schleifer, K.H. (1995) Phylogenetic identification and in situ detection of individual microbial cells without cultivation. Microbiol. Rev. 59, 143-169.
5. Anderson, J.I. and Heffernan, W.P. (1965) Isolation and characterization of filterable marine bacteria. J. Bacteriol. 90, 1713-1718.
6. Arana, I., Muela, A., Iriberri, J., Egea, L. and Barcina, I. (1992) Role of hydrogen peroxide in loss of culturability mediated by visible light in Escherichia coli in a freshwater ecosystem. Appl. Environ. Microbiol. 58, 3903-3907.
7. Asakura, H., Makino, S., Takagi, T., Kuri, A., Kurazono, T., Watarai, M. and Shirahata, T. (2002) Passage in mice causes a change in the ability of Salmonella enterica serovar Oranienburg to survive NaCl osmotic stress: resuscitation from the viable but non-culturable state. FEMS Microbiol. Lett. 212, 87-93.
8. Bachman, M.A. and Swanson, M.S. (2001) RpoS co-operates with other factors to induce Legionella pneumophila virulence in the stationary phase. Mol. Microbiol. 40, 1201-1214.
9. Barer, M.R., Gribbon, L.T., Harwood, C.R. and Nwoguh, C.E. (1993) The viable but not culturable hypothesis and medical bacteriology. Rev. Med. Microbiol. 4, 183-191.
10. Barer, M.R., Kaprelyants, A.S., Weichart, D.H., Harwood, C.R., Kell, D.B. (1998) Microbial stress and culturability: conceptual and operational domains. Microbiology 144, 2009-2010.
11. Barer, M.R. and Harwood, C.R. (1999) Bacterial viability and culturability. Adv. Microb. Physiol. 41, 93-137.
12. Barker, R.L., Gracey, D.E.F., Irwin, A.J., Pipasts, P. and Leiska, E. (1983) Liberation of staling aldehydes during storage of beer. J. Inst. Brewing 89, 411-415.
13. Baross, J.A. and Deming, J.W. (1983) Growth of black smoker bacteria at temperatures of at least 250°C. Nature 303, 423-426.
14. Barrow, P.A., Lovell, M.A. and Barber, L.Z. (1996) Growth suppression in early-stationary-phase nutrient broth cultures of Salmonella typhimurium and Escherichia coli is genus specific and not regulated by sigma. S. J. Bacteriol. 178, 3072-3076.
15. Batchelor, S.E., Cooper, M., Chhabra, S.R., Glover, L.A., Stewart, G.S., Williams, P. and Prosser, J.I. (1997) Cell density-regulated recovery of starved biofilm populations of ammonia-oxidizing bacteria. Appl. Environ. Microbiol. 63, 2281-2286.
16. Bateman, A. and Bycroft, M. (2000) The structure of a LysM domain from E. coli membrane-bound lytic murein transglycosylase D (MltD). J. Mol. Biol. 299, 1113-1119.
17. Bentley, S.D., Chater, K.F., Cerdeno-Tarraga, A.-M., Challis, G.L., Thomson, N.R., James, K.D., Harris, D.E., Quail, M.A., Kieser, H., Harper, D., Bateman, A., Brown, S., Chandra, G., Chen, C.W., Collins, M., Cronin, A., Fraser, A., Goble, A., Hidalgo, J., Hornsby, T., Howarth, S., Huang, C.-H., Kieser, T., Larke, L., Murphey, L., Oliver, K., O'Neil, S., Rabbinowitsch, E., Rajandream, M.-A., Rutherford, K., Rutter, S., Seeger, K., Saunders, D., Sharp, S., Squares, R., Squares, S., Taylor, K., Warren, T., Wietzorrek, A., Woodward, J., Barrell, B.G., Parkhill, J. and Hopwood, D.A. (2002) Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417, 141-147.
18. Berger, A.S. (1992) Dying and death in law and medicine: a forensic primer for health and legal professionals. Praeger Publishers, Westport, Conn.
19. Berlin, D.L., Herson, D.S., Hicks, D.T. and Hoover, D.G. (1999) Response of pathogenic Vibrio species to high hydrostatic pressure. Appl. Environ. Microbiol. 65, 2776-2780.
20. Besnard, V., Federighi, M. and Cappelier, J.M. (2000) Development of a direct viable count procedure for the investigation of VBNC state in Listeria monocytogenes. Lett. Appl. Microbiol. 31, 77-81.
21. Betts, J.C., Lukey, P.T., Robb, L.C., McAdam, R.A. and Duncan, K. (2002) Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profiling. Mol. Microbiol. 43, 717-731.
22. Biketov, S., Mukamolova, G.V., Potapov, V., Gilenkov, E., Vostroknutova, G., Kell, D.B., Young, M. and Kaprelyants, A.S. (2000) Culturability of Mycobacterium tuberculosis cells isolated from murine macrophages: a bacterial growth factor promotes recovery. FEMS Immunol. Med. Microbiol. 29, 233-240.
23. Binnerup, S.J., Jensen, D.F., Thordal-Christensen, H. and Sorensen, J. (1993) Detection of viable, but not-culturable Pseudomonas fluorescens DF57 in soil using a microcolony epifluorescence technique. FEMS Microbiol. Ecol. 12, 97-105.
24. Bloemberg, G.V., O'Toole, G.A., Lugtenberg, B.J. and Kolter, R. (1997) Green fluorescent protein as a marker for Pseudomonas spp. Appl. Environ. Microbiol. 63, 4543-4551.
25. Bloomfield, S.F., Stewart, G.S., Dodd, C.E., Booth, I.R. and Power, E.G. (1998) The viable but non-culturable phenomenon explained? Microbiology UK 144, 1-3.
26. Bogosian, G., Aardema, N.D., Bourneuf, E.V., Morris, P.J. and O'Neil, J.P. (2000) Recovery of hydrogen peroxide-sensitive culturable cells of Vibrio vulnificus gives the appearance of resuscitation from a viable but non-culturable state. J. Bacteriol. 182, 5070-5075.
27. Bogosian, G., Morris, P.J. and O'Neil, J.P. (1998) A mixed culture recovery method indicates that enteric bacteria do not enter the viable but non-culturable state. Appl. Environ. Microbiol. 64, 1736-1742.
28. Bogosian, G., Sammons, L.E., Morris, P.J., O'Neil, J.P., Heitkamp, M.A. and Weber, D.B. (1996) Death of the Escherichia coli K-12 strain W3110 in soil and water. Appl. Environ. Microbiol. 62, 4114-4120.
29. Boon, C., Li, R., Qi, R. and Dick, T. (2001) Proteins of Mycobacterium bovis BCG induced in the Wayne dormancy model. J. Bacteriol. 183, 2672-2676.
30. Boshnakov, R., Romanova, I.M., Zigangirova, N.A. and Gintsburg, A.L. (2001) Differential gene expression in culturable and non-culturable Salmonella typhimurium. Mol. Gen. Mikrobiol. Virusol. 3, 8-12.
31. Boucher, S.N., Slater, E.R., Chamberlain, A.H. and Adams, M.R. (1994) Production and viability of coccoid forms of Campylobacter jejuni. J. Appl. Bacteriol. 77, 303-307.
32. Bovill, R.A. and Mackey, B.M. (1997) Resuscitation of 'non-culturable' cells from aged cultures of Campylobacter jejuni. Microbiology 143, 1575-1581.
33. Brooks, J.V., Furney, S.K. and Orme, I.M. (1999) Metronidazole therapy in mice infected with tuberculosis. Antimicrob. Agents Chemother. 43, 1285-1288.
34. Bussmann, I., Philipp, B. and Schink, B. (2001) Factors influencing the cultivability of lake water bacteria. J. Microbiol. Methods 47, 41-50.
35. Caipo, M.L., Duffy, S., Zhao, L. and Schaffner, D.W. (2002) Bacillus megaterium spore germination is influenced by inoculum size. J. Appl. Microbiol. 92, 879-884.
36. Calcott, P.H. and Postgate, J.R. (1972) On substrate-accelerated death in Klebsiella aerogenes. J. Gen. Microbiol. 70, 115-122.
37. Cao, J.G. and Meighen, E.A. (1989) Purification and structural identification of an autoinducer for the luminescence system of Vibrio harveyi. J. Biol. Chem. 264, 21670-21676.
38. Cappelier, J.M., Minet, J., Magras, C., Colwell, R.R. and Federighi, M. (1999) Recovery in embryonated eggs of viable but nonculturable Campylobacter jejuni cells and maintenance of ability to adhere to HeLa cells after resuscitation. Appl. Environ. Microbiol. 65, 5154-5157.
39. Cashel, M. (1975) Regulation of bacterial ppGpp and pppGpp. Annu. Rev. Microbiol. 29, 301-318.
40. Cashel, M., Gentry, D.R., Hernandez, V.J. and Vinella, D. (1996) The stringent response. In: Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology (F.C. Neidhardt, ed.), pp. 1458-1496. American Society for Microbiology, Washington.
41. Casula, G. and Cutting, S.M. (2002) Bacillus probiotics: spore germination in the gastrointestinal tract. Appl. Environ. Microbiol. 68, 2344-2352.
42. Chaiyanan, S., Huq, A., Maugel, T. and Colwell, R.R. (2001) Viability of the nonculturable Vibrio cholerae O1 and O139. Syst. Appl. Microbiol. 24, 331-341.
43. Chmielewski, R.A. and Frank, J.F. (1995) Formation of viable but non-culturable Salmonella during starvation in chemically defined solutions. Lett. Appl. Microbiol. 20, 380-384.
44. Cho, J.C. and Kim, S.J. (1999a) Green fluorescent protein-based direct viable count to verify a viable but non-culturable state of Salmonella typhi in environmental samples. J. Microbiol. Methods 36, 227-235.
45. Cho, J.C. and Kim, S.J. (1999b) Viable, but non-culturable, state of a green fluorescence protein-tagged environmental isolate of Salmonella typhi in groundwater and pond water. FEMS Microbiol. Lett. 170, 257-264.
46. Christensen, S.K., Mikkelsen, M., Pedersen, K. and Gerdes, K. (2001) RelE, a global inhibitor of translation, is activated during nutritional stress. Proc. Natl. Acad. Sci. USA 98, 14328-14333.
47. Cole, S.T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S.V., Eiglmeier, K., Gas, S., Barry, C.E., Tekaia, F., Badcock, K., Basham, D., Brown, D., Chillingworth, T., Connor, R., Davies, R., Devlin, K., Feltwell, T., Gentles, S., Hamlin, N., Holroyd, S., Hornby, T., Jagels, K., Krogh, A., McLean, J., Moule, S., Murphy, L., Oliver, K., Osborne, J., Quail, M.A., Rajandream, M.A., Rogers, J., Rutter, S., Seeger, K., Skelton, J., Squares, R., Squares, S., Sulston, J.E., Taylor, K., Whitehead, S. and Barrell, B.G. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393, 537-544.
48. Cole, S.T., Eiglmeier, K., Parkhill, J., James, K.D., Thomson, N.R., Wheeler, P.R., Honore, N., Garnier, T., Churcher, C., Harris, D., Mungall, K., Basham, D., Brown, D., Chillingworth, T., Connor, R., Davies, R.M., Devlin, K., Duthoy, S., Feltwell, T., Fraser, A., Hamlin, N., Holroyd, S., Hornsby, T., Jagels, K., Lacroix, C., Maclean, J., Moule, S., Murphy, L., Oliver, K., Quail, M.A., Rajandream, M.A., Rutherford, K.M., Rutter, S., Seeger, K., Simon, S., Simmonds, M., Skelton, J., Squares, R., Squares, S., Stevens, K., Taylor, K., Whitehead, S., Woodward, J.R. and Barrell, B.G. (2001) Massive gene decay in the leprosy bacillus. Nature 409, 1007-1011.
49. Colwell, R.R., Brayton, P., Herrington, D., Tall, B., Huq, A. and Levine, M.M. (1996) Viable but non-culturable Vibrio cholerae O1 revert to a cultivable state in the human intestine. World J. Microbiol. Biotechnology 12, 28-31.
50. Corper, H.J. and Cohn, M.L. (1933) The viability and virulence of old cultures of tubercule bacille. Studies on twelve-year broth cultures maintained at incubator temperature. Am. Rev. Tuberc. 28, 856-874.
51. Crowe, J.H. and Clegg, J.S. (1973) Anhydrobiosis. Dowden, Hutchinson & Ross, Stroudburg, PA.
52. Curtis, T.P., Sloan, W.T. and Scannell, J.W. (2002). Estimating prokaryotic diversity and its limits. Proc Natl Acad Sci USA 99, 10494-10499.
53. Danese, P.N., Pratt, L.A. and Kolter, R. (2001) Biofilm formation as a developmental process. Methods Enzymol. 336, 19-26.
54. Davey, H.M., Kaprelyants, A.S., Weichart, D.H. and Kell, D.B. (1999) Approaches to the estimation of microbial viability using flow cytometry. In: Current Protocols in Cytometry: Volume 11 Microbial Cytometry. (J.P. Robinson, ed.), pp. 11.3.1-11.3.20. Wiley, New York.
55. Davey, H.M. and Kell, D.B. (1996) Flow cytometry and cell sorting of heterogeneous microbial populations: the importance of single-cell analyses. Microbiol. Rev. 60, 641-696.
56. Davies, D.G., Parsek, M.R., Pearson, J.P., Iglewski, B.H., Costerton, J.W. and Greenberg, E.P. (1998) The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science 280, 295-298.
57. Dawes, E.A. and Senior, P.J. (1973) The role of energy reserve polymers in microorganisms. Adv. Microb. Physiol. 10, 135-249.
58. de Wit, D., Wootton, M., Dhillon, J. and Mitchison, D.A. (1995) The bacterial DNA content of mouse organs in the Cornell model of dormant tuberculosis. Tuber. Lung Dis. 76, 555-562.
59. Decross, A.J. and Marshall, B.J. (1993) The role of Helicobacter pylori in acid-peptic disease. Am. J. Med. Sci. 306, 381-392.
60. del Mar Lleo, M., Pierobon, S., Tafi, M.C., Signoretto, C. and Canepari, P. (2000) mRNA detection by reverse transcription-PCR for monitoring viability over time in an Enterococcus faecalis viable but non-culturable population maintained in a laboratory microcosm. Appl. Environ. Microbiol. 66, 4564-4567.
61. Deretic, V. and Fratti, R.A. (1999) Mycobacterium tuberculosis phagosome. Mol. Microbiol. 31, 1603-1609.
62. Devlin, J.P. (1997) High throughput screening: the discovery of bioactive substances. Marcel Dekker, New York.
63. Dhillon, J., Allen, B.W., Hu, Y.M., Coates, A.R. and Mitchison, D.A. (1998) Metronidazole has no anti-bacterial effect in Cornell model murine tuberculosis. Int. J. Tuberc. Lung Dis. 2, 736-742.
64. Dhillon, J., Dickinson, J.M., Sole, K. and Mitchison, D.A. (1996) Preventive chemotherapy of tuberculosis in Cornell model mice with combinations of rifampin, isoniazid, and pyrazinamide. Antimicrob. Agents Chemother. 40, 552-555.
65. Didenko, L.V., Konstantinova, N.D., Solokhina, L.V., Pushkareva, V.I. and Litvin, V. (2002) Ultrastructure of Yersinia pseudotuberculosis in the process of their reversible transition into the dormant (non-culturable) state in association with blue-green algae. Zh. Mikrobiol. Epidemiol. Immunobiol. 1, 17-23.
66. Dietzler, D.N., Leckie, M.P., Lais, C.J., Henry, D.A., Rothert, J.H. and Ferguson, R.M. (1979) Periodic inventory review as a strategy for survival in Escherichia coli. The observation of precisely timed, rapid, and simultaneous shifts in glycogen synthesis and glucose utilization in the absence of an external stimulus during prolonged nitrogen starvation. J. Biol. Chem. 254, 8288-8294.
67. Domingue, G.J., Sr. and Woody, H.B. (1997) Bacterial persistence and expression of disease. Clin. Microbiol. Rev. 10, 320-344.
68. Domingue, G.J., Thomas, R., Walters, F., Serrano, A. and Heidger, P.M., Jr. (1993) Cell wall deficient bacteria as a cause of idiopathic hematuria. J. Urol. 150, 483-485.
69. Dubrow, E.L. (1976) Reactivation of tuberculosis: a problem of aging. J. Am. Geriatr. Soc. 24, 481-487.
70. Duda, V.I., Pronin, S.V., El'-Registan, G.I., Kaprel'iants, A.S. and Mitiushina, L.L. (1982) Formation of resting refractile cells in Bacillus cereus as affected by an autoregulatory factor. Mikrobiologiia 51, 77-81.
71. Dukan, S., Levi, Y. and Touati, D. (1997) Recovery of culturability of an HOCl-stressed population of Escherichia coli after incubation in phosphate buffer: resuscitation or regrowth? Appl. Environ. Microbiol. 63, 4204-4209.
72. Dukan, S. and Nystrom, T. (1999) Oxidative stress defense and deterioration of growth-arrested Escherichia coli cells. J. Biol. Chem. 274, 26027-26032.
73. Edwards, C. (2000) Problems posed by natural environments for monitoring microorganisms. Mol. Biotechnol. 15, 211-223.
74. Eguchi, M., Fujiwara, E. and Miyamoto, N. (2000) Survival of Vibrio anguillarum in freshwater environments: adaptation or debilitation? J. Infect. Chemother. 6, 126-129.
75. Eisenstark, A., Miller, C., Jones, J. and Leven, S. (1992) Escherichia coli genes involved in cell survival during dormancy: role of oxidative stress. Biochem. Biophys. Res. Commun. 188, 1054-1059.
76. Eishi, Y., Suga, M., Ishige, I., Kobayashi, D., Yamada, T., Takemura, T., Takizawa, T., Koike, M., Kudoh, S., Costabel, U., Guzman, J., Rizzato, G., Gambacorta, M., du Bois, R., Nicholson, A.G., Sharma, O.P. and Ando, M. (2002) Quantitative analysis of mycobacterial and propionibacterial DNA in lymph nodes of Japanese and European patients with sarcoidosis. J. Clin. Microbiol. 40, 198-204.
77. Ekweozor, C.C., Nwoguh, C.E. and Barer, M.R. (1998) Transient increases in colony counts observed in declining populations of Campylobacter jejuni held at low temperature. FEMS Microbiol. Lett. 158, 267-272.
78. Ericsson, M., Hanstorp, D., Hagberg, P., Enger, J. and Nystrom, T. (2000) Sorting out bacterial viability with optical tweezers. J. Bacteriol. 182, 5551-5555.
79. Evdokimova, N.V., Dorofeev, A.G. and Panikov, N.S. (1994) Dynamics of survival and transition to dormant state of nitrogen-starving bacteria Pseudomonas fluorescens. Microbiology (Rus.) 63, 195-204.
80. Falke, J.J., Bass, R.B., Butler, S.L., Chervitz, S.A. and Danielson, M.A. (1997) The two-component signaling pathway of bacterial chemotaxis: a molecular view of signal transduction by receptors, kinases, and adaptation enzymes. Annu. Rev. Cell Dev. Biol. 13, 457-512.
81. Fegatella, F. and Cavicchioli, R. (2000) Physiological responses to starvation in the marine oligotrophic ultramicrobacterium Sphingomonas sp. strain RB2256. Appl. Environ. Microbiol. 66, 2037-2044.
82. Fegatella, F., Lim, J., Kjelleberg, S. and Cavicchioli, R. (1998) Implications of rRNA operon copy number and ribosome content in the marine oligotrophic ultramicrobacterium Sphingomonas sp. strain RB2256. Appl. Environ. Microbiol. 64, 4433-4438.
83. Finkel, S.E. and Kolter, R. (2001) DNA as a nutrient: novel role for bacterial competence gene homologs. J. Bacteriol. 183, 6288-6293.
84. Fischer-Le Saux, M., Hervio-Heath, D., Loaec, S., Colwell, R.R. and Pommepuy, M. (2002) Appl Environ Microbiol 68, 5641-5646.
85. Flynn, J.L. and Chan, J. (2001) Tuberculosis: latency and reactivation. Infect. Immun. 69, 4195-4201.
86. Fredricks, D.N. and Relman, D.A. (1996) Sequence-based identification of microbial pathogens - a reconsideration of Koch's postulates. Clin. Microbiol. Rev. 9, 18-33.
87. Fredricks, D.N. and Relman, D.A. (2001) Localization of Tropheryma whippelii rRNA in tissues from patients with Whipple's disease. J. Infect. Dis. 183, 1229-1237.
88. Freeman, R., Dunn, J., Magee, J. and Barrett, A. (2002) The enhancement of isolation of mycobacteria from a rapid liquid culture system by broth culture supernate of Micrococcus luteus. J. Med. Microbiol. 51, 92-93.
89. Freestone, P.P., Haigh, R.D., Williams, P.H. and Lyte, M. (1999) Stimulation of bacterial growth by heat-stable, norepinephrine-induced autoinducers. FEMS Microbiol. Lett. 172, 53-60.
90. Freestone, P.P., Lyte, M., Neal, C.P., Maggs, A.F., Haigh, R.D. and Williams, P.H. (2000) The mammalian neuroendocrine hormone norepinephrine supplies iron for bacterial growth in the presence of transferrin or lactoferrin. J. Bacteriol. 182, 6091-6098.
91. Frenkiel-Krispin, D., Levin-Zaidman, S., Shimoni, E., Wolf, S.G., Wachtel, E.J., Arad, T., Finkel, S.E., Kolter, R. and Minsky, A. (2001) Regulated phase transitions of bacterial chromatin: a non-enzymatic pathway for generic DNA protection. Embo J. 20, 1184-1191.
92. Fuqua, C., Parsek, M.R. and Greenberg, E.P. (2001) Regulation of gene expression by cell-to-cell communication: Acyl-homoserine lactone quorum sensing. Ann. Rev. Genet. 35, 439-468.
93. Gallant, J. and Cashel, M. (1967) On the mechanism of amino acid control of ribonucleic acid biosynthesis. J. Mol. Biol. 25, 545-553.
94. Garcia-Lara, J., Martinez, J., Vilamu, M. and Vives-Rego, J. (1993) Effect of previous growth conditions on the starvation-survival of Escherichia coli in seawater. J. Gen. Microbiol. 139, 1425-1431.
95. Garcia-Lara, J., Shang, L.H. and Rothfield, L.I. (1996) An extracellular factor regulates expression of sdiA, a transcriptional activator of cell division genes in Escherichia coli. J. Bacteriol. 178, 2742-2748.
96. Ghezzi, J.I. and Steck, T.R. (1999) Induction of the viable but non-culturable condition in Xanthomonas campestris pv. campestris in liquid microcosms and sterile soil. FEMS Microbiol. Ecol. 30, 203-208.
97. Giaever, G., Shoemaker, D.D., Jones, T.W., Liang, H., Winzeler, E.A., Astromoff, A. and Davis, R.W. (1999) Genomic profiling of drug sensitivities via induced haploinsufficiency. Nature Genetics 21, 278-283.
98. Gilbert, P., Maira-Litran, T., McBain, A.J., Rickard, A.H. and Whyte, F.W. (2002) The physiology and collective recalcitrance of microbial biofilm communities. Adv. Microb. Physiol. 46, 202-256.
99. Gobel, U.B. (1995) Phylogenetic amplification for the detection of uncultured bacteria and the analysis of complex microbiota. J. Microbiol. Methods 23, 117-128.
100. Gong, L., Takayama, K. and Kjelleberg, S. (2002) Role of spot-dependent ppGpp accumulation in the survival of light-exposed starved bacteria. Microbiology 148, 559-570.
101. Goodrich-Blair, H. and Kolter, R. (2000) Homocysteine thiolactone is a positive effector of sigma(S) levels in Escherichia coli. FEMS Microbiol. Lett. 185, 117-121.
102. Gould, G.W. and Hurst, A. (1969) The Bacterial Spore. 215 pp. Academic Press, London, New York.
103. Grey, B. and Steck, T.R. (2001a) Concentrations of copper thought to be toxic to Escherichia coli can induce the viable but non-culturable condition. Appl. Environ. Microbiol. 67, 5325-5327.
104. Grey, B.E. and Steck, T.R. (2001b) The viable but non-culturable state of Ralstonia solanacearum may be involved in long-term survival and plant infection. Appl. Environ. Microbiol. 67, 3866-3872.
105. Gribbon, L.T. and Barer, M.R. (1995) Oxidative metabolism in non-culturable Helicobacter pylori and Vibrio vulnificus cells studied by substrate-enhanced tetrazolium reduction and digital image processing. Appl. Environ. Microbiol. 61, 3379-3384.
106. Gupta, S., Pandit, S.B., Srinivasan, N. and Chatterji, D. (2002) Proteomics analysis of carbon-starved Mycobacterium smegmatis: induction of Dps-like protein. Protein. Eng. 15, 503-512.
107. Haller, C.M., Rolleke, S., Vybiral, D., Witte, A. and Velimirov, B. (2000) Investigation of 0.2 micron filterable bacteria from the Western Mediterranean Sea using a molecular approach: dominance of potential starvation forms. FEMS Microbiol. Ecol. 31, 153-161.
108. Harrison, A.P. (1960) The response of Bacterium lactis aerogenes when held at growth temperatures in absence of nutriment: an analysis of survival curves. Proc. R. Soc. London 152, 418-428.
109. Hayflick, L. and Moorehead, P.S. (1961) The serial cultivation of human diploid cell strains. Exp. Cell Res. 25, 585-621.
110. Head, I.M., Saunders, J.R. and Pickup, R.W. (1998) Microbial evolution, diversity, and ecology: a decade of ribosomal RNA analysis of uncultivated microorganisms. Microbial. Ecology 35, 1-21.
111. Heim, S., Del Mar Lleo, M., Bonato, B., Guzman, C.A. and Canepari, P. (2002). J Bacteriol 184, 6739-6745.
112. Henderson, B., Poole, S. and Wilson, M. (1996) Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis. Microbiol. Rev. 60, 316-341.
113. Hengge-Aronis, R. (1993) The role of rpoS in early stationary-phase gene regulation in Escherichia coli. In: Starvation in Bacteria (S. Kjelleberg, ed.), pp. 171-200. Plenum Press, New York.
114. Hengge-Aronis, R. (1999) Interplay of global regulators and cell physiology in the general stress response of Escherichia coli. Curr. Opin. Microbiol. 2, 148-152.
115. Hentzer, M., Riedel, K., Rasmussen, T.B., Heydorn, A., Andersen, J.B., Parsek, M.R., Rice, S.A., Eberl, L., Molin, S., Hoiby, N., Kjelleberg, S. and Givskov, M. (2002) Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology 148, 87-102.
116. Herbert, K.C. and Foster, S.J. (2001) Starvation survival in Listeria monocytogenes: characterisation of the response and the role of known and novel components. Microbiology 147, 2275-2284.
117. Hernández-Pando, R., Jeyanathan, M., Mengistu, G., Aguilar, D., Orozco, H., Harboe, M., Rook, G.A.W. and Bjune, G. (2000) Persistence of DNA from Mycobacterium tuberculosis in superficially normal lung tissue during latent infection. Lancet 356, 2133-2138.
118. Hirsch, C.F. and Ensign, J.C. (1976) Heat activation of Streptomyces viridochromogenes spores. J. Bacteriol. 126, 24-30.
119. Hirsch, P. (1986) Microbial life at extremely low nutrient levels. Adv. Space Res. 6, 287-298.
120. Hoch, J.A. (2000) Two-component and phosphorelay signal transduction. Curr. Opin. Microbiol. 3, 165-170.
121. Hoch, J.A. (2002) Control of signal transduction in the sporulation phosphorelay. In: Signals, Switches, Regulons and Cascades: Control of Bacterial Gene Expression (D.A. Hodgson and C.M. Thomas, eds), pp. 199-212. Cambridge University Press, Cambridge.
122. Hoch, J.A. and Silhavy, T.J. (1995) Two component signal transduction. 488 pp. The American Society for Microbiology, Washington, DC.
123. Hofle, M. (1983) Long-term changes in chemostat cultures of Cytophagajohnsonae. Appl. Environ. Microbiol. 46, 1045-1053.
124. Honer zu Bentrup, K. and Russell, D.G. (2001) Mycobacterial persistence: adaptation to a changing environment. Trends Microbiol 9, 597-605.
125. Hood, M.A., Guckert, J.B., White, D.C. and Deck, F. (1986) Effect of nutrient deprivation on lipid, carbohydrate, DNA, RNA, and protein levels in Vibrio cholerae. Appl. Environ. Microbiol. 52, 788-793.
126. Hu, Y. and Coates, A.R. (2001) Increased levels of sigJ mRNA in late stationary phase cultures of Mycobacterium tuberculosis detected by DNA array hybridisation. FEMS Microbiol. Lett. 202, 59-65.
127. Hu, Y., Mangan, J.A., Dhillon, J., Sole, K.M., Mitchison, D.A., Butcher, P.D. and Coates, A.R. (2000) Detection of mRNA transcripts and active transcription in persistent Mycobacterium tuberculosis induced by exposure to rifampin or pyrazinamide. J. Bacteriol. 182, 6358-6365.
128. Hu, Y.M., Butcher, P.D., Sole, K., Mitchison, D.A. and Coates, A.R. (1998) Protein synthesis is shutdown in dormant Mycobacterium tuberculosis and is reversed by oxygen or heat shock. FEMS Microbiol. Lett. 158, 139-145.
129. Huber, R., Huber, H. and Stetter, K.O. (2000) Towards the ecology of hyperthermophiles: biotopes, new isolation strategies and novel metabolic properties. FEMS Microbiol. Rev. 24, 615-623.
130. Huisman, G.W. and Kolter, R. (1994) Sensing starvation: a homoserine lactone-dependent signaling pathway in Escherichia coli. Science 265, 537-539.
131. Islam, M.S., Hossain, M.A., Khan, S.I., Khan, M.N., Sack, R.B., Albert, M.J., Huq, A. and Colwell, R.R. (2001) Survival of Shigella dysenteriae type 1 on fomites. J. Health Popul. Nutr. 19, 177-182.
132. Islam, M.S., Rahim, Z., Alam, M.J., Begum, S., Moniruzzaman, S.M., Umeda, A., Amako, K., Albert, M.J., Sack, R.B., Huq, A. and Colwell, R.R. (1999) Association of Vibrio cholerae O1 with the cyanobacterium, Anabaena sp., elucidated by polymerase chain reaction and transmission electron microscopy. Trans. R. Soc. Trop. Med. Hyg. 93, 36-40.
133. Jang, J.W., Kim, S.J. and Park, Y.H. (2002) Growth-stimulating proteinaceous factor from Corynebacterium glutamicam. Abstract presented at the 102nd General Meeting of the American Society for Microbiology. ASM, Salt Lake City.
134. Janssen, P.H., Yates, P.S., Grinton, B.E., Taylor, P.M. and Sait, M. (2002). Improved culturability of soil bacteria and isolation in pure culture of novel members of the divisions Acidobacteria, Actinobacteria, Proteobacteria, and Verrucomicrobia. Appl Environ Microbiol 68, 2391-2396.
135. Jishage, M., Kvint, K., Shingler, V. and Nystrom, T. (2002) Regulation of sigma factor competition by the alarmone ppGpp. Genes Dev. 16, 1260-1270.
136. Johnston, M.D. and Brown, M.H. (2002) An investigation into the changed physiological state of Vibrio bacteria as a survival mechanism in response to cold temperatures and studies on their sensitivity to heating and freezing. J. Appl. Microbiol. 92, 1066-1077.
137. Kaeberlein, T., Lewis, K. and Epstein, S.S. (2002). Isolating "uncultivable" microorganisms in pure culture in a simulated natural environment. Science 296, 1127-1129.
138. Kaiser, D. and Losick, R. (1993) How and why bacteria talk to each other. Cell 73, 873-885.
139. Kalakoutskii, L.V. and Pouzharitskaja, L.M. (1973) The Streptomyces spore: its distinct features and germinal behaviour. Soc. Appl. Bacteriol. Symp. Ser. 2, 155-178.
140. Kalmbach, S., Manz, W. and Szewzyk, U. (1997) Isolation of new bacterial species from drinking water biofilms and proof of their in situ dominance with highly specific 16S rRNA probes. Appl. Environ. Microbiol. 63, 4164-4170.
141. Kaprelyants, A.S., Gottschal, J.C. and Kell, D.B. (1993) Dormancy in non-sporulating bacteria. FEMS Microbiol. Rev. 10, 271-285.
142. Kaprelyants, A.S. and Kell, D.B. (1992) Rapid assessment of bacterial viability and vitality using rhodamine 123 and flow cytometry. J. Appl. Bacteriol. 72, 410-422.
143. Kaprelyants, A.S. and Kell, D.B. (1993) Dormancy in stationary-phase cultures of Micrococcus luteus: flow cytometric analysis of starvation and resuscitation. Appl. Environ. Microbiol. 59, 3187-3196.
144. Kaprelyants, A.S. and Kell, D.B. (1996) Do bacteria need to communicate with each other for growth? Trends Microbiol. 4, 237-242.
145. Kaprelyants, A.S., Mukamolova, G.V. and Kell, D.B. (1994) Estimation of dormant Micrococcus luteus cells by penicillin lysis and by resuscitation in cell-free spent medium at high dilution. FEMS Microbiol. Lett. 115, 347-352.
146. Kaprelyants, A.S., Mukamolova, G.V., Kormer, S.S., Weichart, D.H., Young, M. and Kell, D.B. (1999) Intercellular signalling and the multiplication of prokaryotes: bacterial cytokines. Symp. Soc. Gen. Microbiol. 57, 33-69.
147. Keer, J., Smeulders, M.J., Gray, K.M. and Williams, H.D. (2000) Mutants of Mycobacterium smegmatis impaired in stationary-phase survival. Microbiology 146, 2209-2217.
148. Keer, J., Smeulders, M.J. and Williams, H.D. (2001) A purF mutant of Mycobacterium smegmatis has impaired survival during oxygen-starved stationary phase. Microbiology 147, 473-481.
149. Keilin, D. (1959) The problem of anabiosis or latent life: history and current concept. Proc. R. Soc. Ser. B. 150, 149-191.
150. Kell, D.B., Kaprelyants, A.S. and Grafen, A. (1995) On pheromones, social behaviour and the functions of secondary metabolism in bacteria. Trends Ecol. Evolution 10, 126-129.
151. Kell, D.B., Kaprelyants, A.S., Weichart, D.H., Harwood, C.R. and Barer, M.R. (1998) Viability and activity in readily culturable bacteria: a review and discussion of the practical issues. Antonie Van Leeuwenhoek 73, 169-187.
152. Kell, D.B., Mukamolova, G.V., Finan, C.L., Zhao, H., Goodacre, R., Kaprelyants, A.S. and Young, M. (2003) Resuscitation of 'uncultured' microorganisms. In: Microbial Diversity and Bioprospecting (A.T. Bull, ed.). American Society for Microbiology, Washington, DC.
153. Kell, D.B. and Young, M. (2000) Bacterial dormancy and culturability: the role of autocrine growth factors. Curr. Opin. Microbiol. 3, 238-243.
154. Khomenko, A.G., Golyshevskaia, V.I., Shaginian, I.A., Safonova, S.G., Nesterenko, L.N., Grishina, T.D., Gintsburg, A.L. and Prozorovskii, S.V. (1994) Is sarcoidosis a chronic persistent infection?. Zh. Mikrobiol. Epidemiol. Immunobiol. 1, 64-68.
155. Khomenko, A.G., Karachunskii, M.A., Dorozhkova, I.R., Chukanov, V.I. and Balta Iu, E. (1980) L-transformation of the mycobacterial population in the process of treating patients with newly detected destructive pulmonary tuberculosis. Probl. Tuberk. 2, 18-23.
156. Khomenko, A.G. and Muratov, V.V. (1993) Epidemiological risks of tuberculous infection foci in patients discharging L-forms of Mycobacterium tuberculosis. Probl. Tuberk. 2, 2-5.
157. Kim, D.S. and Fogler, H.S. (1999) The effects of exopolymers on cell morphology and culturability of Leuconostoc mesenteroides during starvation. Appl. Microbiol. Biotechnol. 52, 839-844.
158. Kim, K.S., Rao, N.N., Fraley, C.D. and Kornberg, A. (2002) Inorganic polyphosphate is essential for long-term survival and virulence factors in Shigella and Salmonella spp. Proc. Natl. Acad. Sci. USA 99, 7675-7680.
159. Kjelleberg, S., Albertson, N., Flardh, K., Holmquist, L., Jouper-Jaan, A., Marouga, R., Ostling, J., Svenblad, B. and Weichart, D. (1993) How do non-differentiating bacteria adapt to starvation? Antonie Van Leeuwenhoek 63, 333-341.
160. Kleerebezem, M. and Quadri, L.E. (2001) Peptide pheromone-dependent regulation of anti-microbial peptide production in Gram-positive bacteria: a case of multicellular behavior. Peptides 22, 1579-1596.
161. Kleerebezem, M., Quadri, L.E.N., Kuipers, O.P. and deVos, W.M. (1997) Quorum sensing by peptide pheromones and two-component signal-transduction systems in Gram-positive bacteria. Mol. Microbiol. 24, 895-904.
162. Koch, A.L. (1971) The adaptive responses of Escherichia coli to a feast and famine existence. Adv. Microbial Physiol. 6, 147-217.
163. Kogure, K. and Ikemoto, E. (1997) Wide occurrence of enterohemorragic Escherichia coli 0157 in natural freshwater environment. Nippon. Saikingaku. Zasshi. 52, 601-607.
164. Kogure, K., Simidu, U. and Taga, N. (1979) A tentative direct microscopic method for counting living marine bacteria. Can. J. Microbiol. 25, 415-420.
165. Kolling, G.L. and Matthews, K.R. (2001) Examination of recovery in vitro and in vivo of non-culturable Escherichia coli O157:H7. Appl. Environ. Microbiol. 67, 3928-3933.
166. Kolter, R., Siegele, D.A. and Tormo, A. (1993) The stationary phase of the bacterial life cycle. Annu. Rev. Microbiol. 47, 855-874.
167. Kozdroj, J. and van Elsas, J.D. (2001) Structural diversity of microorganisms in chemically perturbed soil assessed by molecular and cytochemical approaches. J. Microbiol. Methods 43, 197-212.
168. Kuhar, I., van Putten, J.P., Zgur-Bertok, D., Gaastra, W. and Jordi, B.J. (2001) Codon-usage based regulation of colicin K synthesis by the stress alarmone ppGpp. Mol. Microbiol. 41, 207-216.
169. Kurokawa, M., Nukina, M., Nakanishi, H., Tomita, S., Tamura, T. and Shimoyama, T. (1999) Resuscitation from the viable but non-culturable state of Helicobacter pylori. Kansenshogaku Zasshi 73, 15-19.
170. Kuznetsova, Z.A. (1985) Reactivation of pulmonary tuberculosis in patients treated with rifampicin and ethambutol. Probl. Tuberk., 40-42.
171. Lazazzera, B.A. (2001) The intracellular function of extracellular signaling peptides. Peptides 22, 1519-1527.
172. Lazazzera, B.A. and Grossman, A.D. (1998) The ins and outs of peptide signaling. Trends Microbiol. 6, 288-294.
173. Lee, K.-H. and Ruby, E.G. (1995) Symbiotic role of the viable but non-culturable state of Vibrio fischeri in Hawaiian coastal seawater. Appl. Environ. Microbiol. 61, 278-283.
174. Lesn, J., Berthet, S., Binard, S., Rouxel, A. and Humbert, F. (2000) Changes in culturability and virulence of Salmonella typhimurium during long-term starvation under desiccating conditions. Int. J. Food Microbiol. 60, 195-203.
175. Lewis, K. (2000) Programmed death in bacteria. Microbiol. Mol. Biol. Rev. 64, 503-514.
176. Li, Y.H., Hanna, M.N., Svensater, G., Ellen, R.P. and Cvitkovitch, D.G. (2001) Cell density modulates acid adaptation in Streptococcus mutans: implications for survival in biofilms. J. Bacteriol. 183, 6875-6884.
177. Lillebaek, T., Dirksen, A., Baess, I., Strunge, B., Thomsen, V.O. and Andersen, A.B. (2002) Molecular evidence of endogenous reactivation of Mycobacterium tuberculosis after 33 years of latent infection. J. Infect. Dis. 185, 401-404.
178. Lleo, M.M., Bonato, B., Tafi, M.C., Signoretto, C., Boaretti, M. and Canepari, P. (2001) Resuscitation rate in different enterococcal species in the viable but non-culturable state. J. Appl. Microbiol. 91, 1095-1102.
179. Loginov, A.S., Reshetniak, V.I., Mukamolova, G.V., Fedukova, N.G., Il'chenko, A.A., Dudik, T.V. and Kaprel'iants, A.S. (1999) The possibility of Helicobacter pylori being present in the resting state in the gastric mucosa of peptic acid patients after treatment. Ter. Arkh. 71, 13-16.
180. Losick, R. and Kaiser, D. (1997) Why and how bacteria communicate. Sci. Am. 276, 68-73.
181. Lowder, M. and Oliver, J.D. (2001) The use of modified GFP as a reporter for metabolic activity in Pseudomonas putida. Microb. Ecol. 41, 310-313.
182. Lowder, M., Unge, A., Maraha, N., Jansson, J.K., Swiggett, J. and Oliver, J.D. (2000) Effect of starvation and the viable-but-non-culturable state on green fluorescent protein (GFP) fluorescence in GFP-tagged Pseudomonas fluorescens A506. Appl. Environ. Microbiol. 66, 3160-3165.
183. Luna, G.M., Manini, E. and Danovaro, R. (2002) Large fraction of dead and inactive bacteria in coastal marine sediments: comparison of protocols for determination and ecological significance. Appl. Environ. Microbiol. 68, 3509-3513.
184. Lynch, T., Odel, J., Fredericks, D.N., Louis, E.D., Forman, S., Rotterdam, H., Fahn, S. and Relman, D.A. (1997) Polymerase chain reaction-based detection of Tropheryma whippelii in central nervous system Whipple's disease. Ann. Neurol. 42, 120-124.
185. Lyte, M. (1992) The role of catecholamines in Gram-negative sepsis. Med. Hypoth. 37, 255-258.
186. Lyte, M. (1993) The role of microbial endocrinology in infectious disease. J. Endocrinol. 137, 343-345.
187. Lyte, M. and Ernst, S. (1992) Catecholamine-induced growth of Gram-negative bacteria. Life Sci. 50, 203-212.
188. Lyte, M. and Ernst, S. (1993) Alpha-adrenergic and beta-adrenergic-receptor involvement in catecholamine-induced growth of gram-negative bacteria. Biochem. Biophys. Res. Commun. 190, 447-452.
189. MacDonell, M.T. and Hood, M. (1982) Isolation and characterization of ultramicrobacteria from a gulf coast estuary. Appl. Environ. Microbiol. 43, 566-571.
190. Madhavan, H.N., Therese, K.L. and Doraiswamy, K. (2002) Further investigations on the association of Mycobacterium tuberculosis with Eales' disease. Indian J. Ophthalmol. 50, 35-39.
191. Magarinos, B., Romalde, J.L., Barja, J.L. and Toranzo, A.E. (1994) Evidence of a dormant but infective state of the fish pathogen Pasteurella piscicida in seawater and sediment. Appl. Environ. Microbiol. 60, 180-186.
192. Mah, T.F. and O'Toole, G.A. (2001) Mechanisms of biofilm resistance to anti-microbial agents. Trends Microbiol. 9, 34-39.
193. Maiwald, M., von Herbay, A., Persing, D.H., Mitchell, P.P., Abdelmalek, M.F., Thorvilson, J.N., Fredricks, D.N. and Relman, D.A. (2001) Tropheryma whippelii DNA is rare in the intestinal mucosa of patients without other evidence of Whipple disease. Ann. Intern. Med. 134, 115-119.
194. Manefield, M., de Nys, R., Kumar, N., Read, R., Givskov, M., Steinberg, P. and Kjelleberg, S. (1999) Evidence that halogenated furanones from Delisea pulchra inhibit acylated homoserine lactone (AHL)-mediated gene expression by displacing the AHL signal from its receptor protein. Microbiology 145, 283-291.
195. Manefield, M., Rasmussen, T.B., Henzter, M., Andersen, J.B., Steinberg, P., Kjelleberg, S. and Givskov, M. (2002) Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover. Microbiology 148, 1119-1127.
196. Marouga, R. and Kjelleberg, S. (1996) Synthesis of immediate upshift (Iup) proteins during recovery of marine Vibrio sp. strain S14 subjected to long-term carbon starvation. J. Bacteriol. 178, 817-822.
197. Marshall, B.J. and Warren, J.R. (1984) Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1, 1311-1315.
198. Mary, P., Chihib, N.E., Charafeddine, O., Defives, C. and Hornez, J.P. (2002) Starvation survival and viable but non-culturable states in Aeromonas hydrophila. Microb. Ecol. 43, 250-258.
199. Mascher, F., Hase, C., Moenne-Loccoz, Y. and Defago, G. (2000) The viable-but-non-culturable state induced by abiotic stress in the biocontrol agent Pseudomonas fluorescens CHAO does not promote strain persistence in soil. Appl. Environ. Microbiol. 66, 1662-1667.
200. Matsuda, M., Togo, M., Kagawa, S. and Moore, J.E. (2001) PCR cloning of the resuscitation-promoting factor (Rpf) gene from Micrococcus luteus, sequencing and expression in Escherichia coli. Microbios 104, 55-61.
201. Mayfield, C.I., Williams, S.T., Ruddick, S.M. and Hatfield, H.L. (1972) Study on ecology at actinomycetes in soil. IV. Observation on the form and growth of streptomycetes in soil. Soil Biol. Biochem. 4, 79-91.
202. McCune, R.M., Feldmann, F.M., Lambert, H.P. and McDermott, W. (1966a) Microbial persistence. I. The capacity of tubercle bacilli to survive sterilization in mouse tissues. J. Exp. Med. 123, 445-468.
203. McCune, R.M., Feldmann, F.M. and McDermott, W. (1966b) Microbial persistence. II. Characteristics of the sterile state of tubercle bacilli. J. Exp. Med. 123, 469-486.
204. McDougald, D., Rice, S.A. and Kjelleberg, S. (2001) SmcR-dependent regulation of adaptive phenotypes in Vibrio vulnificus. J. Bacteriol. 183, 758-762.
205. McDougald, D., Rice, S.A., Weichart, D. and Kjelleberg, S. (1998) Non-culturability: adaptation or debilitation? FEMS Microbiol. Ecol. 25, 1-9.
206. McGowan, S., Sebaihia, M., Jones, S., Yu, B., Bainton, N., Chan, P.F., Bycroft, B., Stewart, G.S., Williams, P. and Salmond, G.P. (1995) Carbapenem antibiotic production in Erwinia carotovora is regulated by CarR, a homologue of the LuxR transcriptional activator. Microbiology 141, 541-550.
207. Meighen, E.A. (1994) Genetics of bacterial bioluminescence. Annu. Rev. Genet. 28, 117-139.
208. Miguelez, E.M., Martin, C., Hardisson, C. and Manzanal, M.B. (1993) Synchronous germination of Streptomyces antibioticus spores: tool for the analysis of hyphal growth in liquid cultures. FEMS Microbiol. Lett. 109, 123-129.
209. Millet, V. and Lonvaud-Funel, A. (2000) The viable but non-culturable state of wine microorganisms during storage. Lett. Appl. Microbiol. 30, 136-141.
210. Miyazaki, E., Chaisson, R.E. and Bishai, W.R. (1999) Analysis of rifapentine for preventive therapy in the Cornell mouse model of latent tuberculosis. Antimicrob. Agents Chemother. 43, 2126-2130.
211. Moir, A. and Smith, D.A. (1990) The genetics of bacterial spore germination. Annu. Rev. Microbiol. 44, 531-553.
212. Moore, J., Caldwell, P. and Millar, B. (2001) Molecular detection of Campylobacter spp. in drinking, recreational and environmental water supplies. Int. J. Hyg. Environ. Health 204, 185-189.
213. Moore, J.E. (2000) Comparison of basal broth media for the optimal laboratory recovery of Campylobacter jejuni and Campylobacter coli. Ir. J. Med. Sci. 169, 187-189.
214. Morgan, J.A., Rhodes, G. and Pickup, R.W. (1993) Survival of non-culturable Aeromonas salmonicida in lake water. Appl. Environ. Microbiol. 59, 874-880.
215. Morita, R.Y. (1990) The starvation-survival state of microorganisms in nature and its relationship to bioavailable energy. Experientia 46, 813-817.
216. Morita, R.Y. (1997) Bacteria in Oligotrophic Environments. Chapman and Hall, New York.
217. Morrison, D.A. (2002) Is anybody there? Cooperative bacterial gene regulation via peptide signals between Gram-positive bacteria. In: Signals, Switches, Regulons and Cascades: Control of Bacterial Gene Expression (D.A. Hodgson and C.M. Thomas, eds), pp. 231-249. Cambridge University Press, Cambridge.
218. Mukamolova, G.V., Kaprelyants, A.S. and Kell, D.B. (1995a) Secretion of an anti-bacterial factor during resuscitation of dormant cells in Micrococcus luteus cultures held in an extended stationary phase. Antonie Van Leeuwenhoek 67, 289-295.
219. Mukamolova, G.V., Kaprelyants, A.S., Young, D.I., Young, M. and Kell, D.B. (1998a) A bacterial cytokine. Proc. Natl. Acad. Sci. USA 95, 8916-8921.
220. Mukamolova, G.V., Kormer, S.S., Yanopolskaya, N.D. and Kaprelyants, A.S. (1995b) Properties of dormant cells in stationary-phase cultures of Micrococcus luteus during prolonged incubation. Microbiology (Rus.) 64, 284-288.
221. Mukamolova, G.V., Turapov, O.A., Kazaryan, K., Telkov, M., Kaprelyants, A.S., Kell, D.B. and Young, M. (2002a) The rpf gene of Micrococcus luteus encodes an essential secreted growth factor. Mol. Microbiol. 46, 611-621.
222. Mukamolova, G.V., Turapov, O.A., Young, D.I., Kaprelyants, A.S., Kell, D.B. and Young, M. (2002b) A family of autocrine growth factors in Mycobacterium tuberculosis. Mol. Microbiol. 46, 623-635.
223. Mukamolova, G.V., Yanopolskaya, N.D., Kell, D.B. and Kaprelyants, A.S. (1998b) On resuscitation from the dormant state of Micrococcus luteus. Antonie van Leeuwenhoek 73, 237-243.
224. Mukamolova, G.V., Yanopolskaya, N.D., Votyakova, T.V., Popov, V.I., Kaprelyants, A.S. and Kell, D.B. (1995c) Biochemical changes accompanying the long-term starvation of Micrococcus luteus cells in spent growth medium. Arch. Microbiol. 163, 373-379.
225. Neal, C.P., Freestone, P.P., Maggs, A.F., Haigh, R.D., Williams, P.H. and Lyte, M. (2001) Catecholamine inotropes as growth factors for Staphylococcus epidermidis and other coagulase-negative staphylococci. FEMS Microbiol. Lett. 194, 163-169.
226. Nebe-von-Caron, G., Stephens, P.J., Hewitt, C.J., Powell, J.R. and Badley, R.A. (2000) Analysis of bacterial function by multi-colour fluorescence flow cytometry and single cell sorting. J. Microbiol. Methods 42, 97-114.
227. Neidhardt, F.C. (2002) Microbial reaction to environment: bacterial stress responses revisited in the genomic-proteomic era. In: Signals, Switches, Regulons and Cascades: Control of Bacterial Gene Expression (D.A. Hodgson and C.M. Thomas, eds), pp. 1-18. Cambridge University Press, Cambridge.
228. Neijssel, O.M. and Tempest, D.W. (1976) The role of energy-splitting reactions in the growth of Klebsiella aerogenes NCTC 418 in aerobic chemostat culture. Arch. Microbiol. 110, 305-311.
229. Nickle, D.C., Learn, G.H., Rain, M.W., Mullins, J.I. and Mittler, J.E. (2002) Curiously modern DNA for a "250 Million-Year-Old" bacterium. J. Mol. Evol. 54, 134-137.
230. Nikolaev, I.A., Prosser, J.I. and Panikov, N.S. (2000) Extracellular factors of adaptation of Pseudomonas fluorescens batch cultures to adverse conditions. Mikrobiologiia 69, 629-635.
231. Nilsson, H.O., Blom, J., Abu-Al-Soud, W., Ljungh, A.A., Andersen, L.P. and Wadstrom, T. (2002) Effect of cold starvation, acid stress, and nutrients on metabolic activity of Helicobacter pylori. Appl. Environ. Microbiol. 68, 11-19.
232. Nilsson, L., Oliver, J.D. and Kjelleberg, S. (1991) Resuscitation of Vibrio vulnificus from the viable but non-culturable state. J. Bacteriol. 173, 5054-5059.
233. Novitsky, J.A. and Morita, R.Y. (1976) Morphological characterization of small cells resulting from nutrient starvation of a psychrophilic marine vibrio. Appl. Environ. Microbiol. 32, 617-622.
234. Nystrom, T. (2001) Not quite dead enough: on bacterial life, culturability, senescence, and death. Arch. Microbiol. 176, 159-164.
235. Nystrom, T., Larsson, C. and Gustafsson, L. (1996) Bacterial defense against aging: role of the Escherichia coli ArcA regulator in gene expression, readjusted energy flux and survival during stasis. EMBO J. 15, 3219-3228.
236. Nystrom, T. and Neidhardt, F.C. (1994) Expression and role of the universal stress protein, UspA, of Escherichia coli during growth arrest. Mol. Microbiol. 11, 537-544.
237. Ohtomo, R. and Saito, M. (2001) Increase in the culturable cell number of Escherichia coli during recovery from saline stress: possible implication for resuscitation from the VBNC state. Microb. Ecol. 42, 208-214.
238. Oliver, J.D. and Bockian, R. (1995) In vivo resuscitation, and virulence towards mice, of viable but non-culturable cells of Vibrio vulnificus. Appl. Environ. Microbiol. 61, 2620-2623.
239. Oliver, J.D., Hite, F., McDougald, D., Andon, N.L. and Simpson, L.M. (1995) Entry into, and resuscitation from, the viable but non-culturable state by Vibrio vulnificus in an estuarine environment. Appl. Environ. Microbiol. 61, 2624-2630.
240. Oliver, J.D., Nilsson, L. and Kjelleberg, S. (1991) Formation of non-culturable Vibrio vulnificus cells and its relationship to the starvation state. Appl. Environ. Microbiol. 57, 2640-2644.
241. Oliver, J.D. and Wanucha, D. (1989) Survival of Vibrio vulnificus at reduced temperatures and elevated nutrient. J. Food Safety 10, 79-86.
242. Ostling, J., McDougald, D., Marouga, R. and Kjelleberg, S. (1997) Global analysis of physiological responses in marine bacteria. Electrophoresis 18, 1441-1450.
243. O'Toole, G., Kaplan, H.B. and Kolter, R. (2000) Biofilm formation as microbial development. Annu. Rev. Microbiol. 54, 49-79.
244. Pai, S.R., Actor, J.K., Sepulveda, E., Hunter, R.L., Jr. and Jagannath, C. (2000) Identification of viable and non-viable Mycobacterium tuberculosis in mouse organs by directed RT-PCR for antigen 85B mRNA. Microb. Pathog. 28, 335-342.
245. Paidhungat, M., Setlow, B., Daniels, W.B., Hoover, D., Papafragkou, E. and Setlow, P. (2002) Mechanisms of induction of germination of Bacillus subtilis spores by high pressure. Appl. Environ. Microbiol. 68, 3172-3175.
246. Paidhungat, M. and Setlow, P. (2000) Role of Ger proteins in nutrient and non-nutrient triggering of spore germination in Bacillus subtilis. J. Bacteriol. 182, 2513-2519.
247. Paludan-Muller, C., Weichart, D., McDougald, D. and Kjelleberg, S. (1996) Analysis of starvation conditions that allow for prolonged culturability of Vibrio vulnificus at low temperature. Microbiology 142, 1675-1684.
248. Parrish, N.M., Dick, J.D. and Bishai, W.R. (1998) Mechanisms of latency in Mycobacterium tuberculosis. Trends Microbiol. 6, 107-112.
249. Petersen, F., Zahner, H., Metzger, J.W., Freund, S. and Hummel, R.P. (1993) Germicidin, an autoregulative germination inhibitor of Streptomyces viridochromogenes NRRL B-1551. J. Antibiot. (Tokyo) 46, 1126-1138.
250. Pitonzo, B.J., Amy, P.S. and Rudin, M. (1999) Resuscitation of microorganisms after gamma irradiation. Radiat. Res. 152, 71-75.
251. Poindexter, J. (1981) Oligotrophy: fast and famine existence. Adv. Microb. Ecology 5, 63-89.
252. Polyanskaya, L.M. and Triger, Y.G. (1990) Self-regulation of Streptomyces spore germination. Dokl. Acad. Nauk 315, 729-730.
253. Postgate, J.R. (1967) Viability measurements and the survival of microbes under minimum stress. Adv. Micr. Physiol. 1, 1-23.
254. Postgate, J.R. (1969) Viable counts and viability. Meth. Microbiol. 1, 611-628.
255. Postgate, J.R. (1976) Death in macrobes and microbes. Symp. Soc. Gen. Microbiol. 26, 1-18.
256. Postgate, J.R. (1995) Danger of sleeping bacteria. In: The Times, November 13th, p. 19, London.
257. Postgate, J.R. and Hunter, J.R. (1962) The survival of starved bacteria. J. Gen. Microbiol. 29, 233-267.
258. Primas, H. (1981) Chemistry, Quantum Mechanics and Reductionism. Springer, Berlin.
259. Primm, T.P., Andersen, S.J., Mizrahi, V., Avarbock, D., Rubin, H. and Barry, C.E., 3rd. (2000) The stringent response of Mycobacterium tuberculosis is required for long-term survival. J. Bacteriol. 182, 4889-4898.
260. Rahman, I., Shahamat, M., Chowdhury, M.A. and Colwell, R.R. (1996) Potential virulence of viable but non-culturable Shigella dysenteriae type 1. Appl. Environ. Microbiol. 62, 115-120.
261. Rahman, I., Shahamat, M., Kirchman, P.A., Russek-Cohen, E. and Colwell, R.R. (1994) Methionine uptake and cytopathogenicity of viable but non-culturable Shigella dysenteriae type 1. Appl. Environ. Microbiol. 60, 3573-3578.
262. Ramaiah, N., Ravel, J., Straube, W.L., Hill, R.T. and Colwell, R.R. (2002) Entry of Vibrio harveyi and Vibrio fischeri into the viable but non-culturable state. J. Appl. Microbiol. 93, 108-116.
263. Rao, N.N. and Kornberg, A. (1999) Inorganic polyphosphate regulates responses of Escherichia coli to nutritional stringencies, environmental stresses and survival in the stationary phase. Prog. Mol. Subcell. Biol. 23, 183-195.
264. Ravel, J., Hill, R.T. and Colwell, R.R. (1994) Isolation of a Vibrio cholerae transposon-mutant with an altered viable but non-culturable response. FEMS Microbiol. Lett. 120, 57-61.
265. Ray, B. and Speck, M.L. (1973) Freeze-injury in bacteria. CRC Crit. Rev. Clin. Lab. Sci. 4, 161-213.
266. Reusch, R.N. and Sadoff, H.L. (1979) 5-N-Alkylresorcinols from encysting Azotobacter vinelandii: isolation and characterization. J. Bacteriol. 139, 448-453.
267. Rinas, U., Hellmuth, K., Kang, R.J., Seeger, A. and Schlieker, H. (1995) Entry of Escherichia coli into stationary phase is indicated by endogenous and exogenous accumulation of nucleobases. Appl. Env. Microbiol. 61, 4147-4151.
268. Rittman, B. (1999) Microbial Ecology of Biofilms. Pergamon Press, New York.
269. Rivers, B. and Steck, T.R. (2001) Viable but non-culturable uropathogenic bacteria are present in the mouse urinary tract following urinary tract infection and antibiotic therapy. Urol. Res. 29, 60-66.
270. Romalde, J.L., Barja, J.L., Magarinos, B. and Toranzo, A.E. (1994) Starvation-survival processes of bacterial fish pathogen Yersinia ruckeri. Syst. Appl. Microbiol. 17, 161-168.
271. Romanova, I.M., Kirillov, M.I., Terekhov, A.A. and Gintsburg, A.L. (1996) Identification of genes controlling the transition of Salmonella typhimurium bacteria to a non-culturable state. Genetika 32, 1184-1190.
272. Rondon, M.R., August, P.R., Bettermann, A.D., Brady, S.F., Grossman, T.H., Liles, M.R., Loiacono, K.A., Lynch, B.A., MacNeil, I.A., Minor, C., Tiong, C.L., Gilman, M., Osburne, M.S., Clardy, J., Handelsman, J. and Goodman, R.M. (2000). Cloning the soil metagenome: a strategy for accessing the genetic and functional diversity of uncultured microorganisms. Appl Environ Microbiol 66, 2541-2547.
273. Roszak, D.B. and Colwell, R.R. (1987) Survival strategies of bacteria in the natural environment. Microbiol. Rev. 51, 365-379.
274. Roszak, D.B., Grimes, D.J. and Colwell, R.R. (1984) Viable but non-recoverable stage of Salmonella enteritidis in aquatic systems. Can. J. Microbiol. 30, 334-338.
275. Rowbury, R.J. (2001) Extracellular sensing components and extracellular induction component alarmones give early warning against stress in Escherichia coli. Adv Microb Physiol 44, 215-257.
276. Rubin, H. (2002) The disparity between human cell senescence in vitro and lifelong replication in vivo. Nature Biotechnol. 20, 675-681.
277. Sait, M., Hugenholtz, P. and Janssen, P.H. (2002). Cultivation of globally distributed soil bacteria from phylogenetic lineages previously only detected in cultivation-independent surveys. Environ Microbiol 4, 654-666.
278. Salmond, G.P., Bycroft, B.W., Stewart, G.S. and Williams, P. (1995) The bacterial 'enigma': cracking the code of cell-cell communication. Mol. Microbiol. 16, 615-624.
279. Scanga, C.A., Mohan, V.P., Joseph, H., Yu, K., Chan, J. and Flynn, J.L. (1999) Reactivation of latent tuberculosis: variations on the Cornell murine model. Infect. Immun. 67, 4531-4538.
280. Schena, M. (2000) Microarray Biochip Technology. Eaton Publishing, Natick, MA.
281. Schuster, K.C., Goodacre, R., Gapes, J.R. and Young, M. (2001) Degeneration of solventogenic Clostridium strains monitored by Fourier transform infrared spectroscopy of bacterial cells. J. Ind. Microbiol. Biotechnol. 27, 314-321.
282. Schut, F., DeVries, E.J., Gottschal, J.C., Robertson, B.R., Harder, W., Prins, R.A. and Button, D.K. (1993) Isolation of typical marine bacteria by dilution culture - growth, maintenance, and characteristics of isolates under laboratory conditions. Appl. Env. Microbiol. 59, 2150-2160.
283. Schut, F., Gottschal, J.C. and Prins, R.A. (1997a) Isolation and characterisation of the marine ultramicrobacterium Sphingomonas sp. strain RB2256. FEMS Microbiol. Rev. 20, 363-369.
284. Schut, F., Prins, R.A. and Gottschal, J.C. (1997b) Oligotrophy and pelagic marine bacteria: Facts and fiction. Aquatic Microbial. Ecol. 12, 177-202.
285. Shahamat, M., Mai, U., Paszko-Kolva, C., Kessel, M. and Colwell, R.R. (1993) Use of autoradiography to assess viability of Helicobacter pylori in water. Appl. Environ. Microbiol. 59, 1231-1235.
286. Shapiro, H.M. (1995a) Practical Flow Cytometry, 3rd edition. John Wiley, New York.
287. Shapiro, H.M. (2000) Membrane potential estimation by flow cytometry. Methods a Companion to Methods in Enzymology 21, 271-279.
288. Shapiro, J.A. (1995b) The significances of bacterial colony patterns. Bioessays 17, 597-607.
289. Sherman, D.R., Voskuil, M., Schnappinger, D., Liao, R., Harrell, M.I. and Schoolnik, G.K. (2001) Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding α-crystallin. Proc. Natl. Acad. Sci. USA 98, 7534-7539.
290. Shleeva, M.O., Bagramyan, K., Telkov, M.V., Mukamolova, G.V., Young, M., Kell, D.B. and Kaprelyants, A.S. (2002) Formation and resuscitation of 'non-culturable' cells of Rhodococcus rhodochrous and Mycobacterium tuberculosis in prolonged stationary phase. Microbiology 148, 1581-1591.
291. Siegele, D.A. and Kolter, R. (1993) Isolation and characterization of an Escherichia coli mutant defective in resuming growth after starvation. Genes Dev. 7, 2629-2640.
292. Signoretto, C., del Mar Lleo, M. and Canepari, P. (2002) Modification of the peptidoglycan of Escherichia coli in the viable but non-culturable state. Curr. Microbiol. 44, 125-131.
293. Signoretto, C., del Mar Lleo, M., Tafi, M.C. and Canepari, P. (2000) Cell wall chemical composition of Enterococcus faecalis in the viable but non-culturable state. Appl. Environ. Microbiol. 66, 1953-1959.
294. Sitnikov, D.M., Schineller, J.B. and Baldwin, T.O. (1996) Control of cell division in Escherichia coli: regulation of transcription of ftsQA involves both rpoS and SdiA-mediated autoinduction. Proc. Natl. Acad. Sci. USA 93, 336-341.
295. Slaughter, J.C. (1999) The naturally occurring furanones: formation and function from pheromone to food. Biol. Rev. 74, 259-276.
296. Smeulders, M.J., Keer, J., Speight, R.A. and Williams, H.D. (1999) Adaptation of Mycobacterium smegmatis to stationary phase. J. Bacteriol. 181, 270-283.
297. Smith, R.J., Newton, A.T., Harwood, C.R. and Barer, M.R. (2002) Active but non-culturable cells of Salmonella enterica serovar Typhimurium do not infect or colonize mice. Microbiology UK 148, 2717-2728.
298. Spector, M.P. (1998) The starvation-stress response (SSR) of Salmonella. Adv. Microb. Physiol. 40, 233-279.
299. Srinivasan, S., Ostling, J., Charlton, T., de Nys, R., Takayama, K. and Kjelleberg, S. (1998) Extracellular signal molecule(s) involved in the carbon starvation response of marine Vibrio sp. strain S14. J. Bacteriol. 180, 201-209.
300. Steinert, M., Emody, L., Amann, R. and Hacker, J. (1997) Resuscitation of viable but non-culturable Legionella pneumophila Philadelphia JR32 by Acanthamoeba castellanii. Appl. Environ. Microbiol. 63, 2047-2053.
301. Stephens, K. (1986) Pheromones among the prokaryotes. CRC Crit. Rev. Microbiol. 13, 309-334.
302. Stock, A.M., Robinson, V.L. and Goudreau, P.N. (2000) Two-component signal transduction. Annu. Rev. Biochem. 69, 183-215.
303. Stoodley, P., Davies, D.G. and Costerton, J.W. (2002) Biofilms as complex differentiated communities. Annu Rev Microbiol. 56, 187-209.
304. Storz, G. and Hengge-Aronis, R. (2000) Bacterial Stress Responses. American Society for Microbiology, Washington, DC.
305. Strauch, M.A. and Hoch, J.A. (1993) Transition-state regulators: sentinels of Bacillus subtilis post-exponential gene expression. Mol. Microbiol. 7, 337-342.
306. Strom, A.R. and Kaasen, I. (1993) Trehalose metabolism in Escherichia coli: stress-protection and stress regulation of gene expression. Mol. Microbiol. 8, 205-210.
307. Sun, Z. and Zhang, Y. (1999) Spent culture supernatant of Mycobacterium tuberculosis H37Ra improves viability of aged cultures of this strain and allows small inocula to initiate growth. J. Bacteriol. 181, 7626-7628.
308. Tada, Y., Ihmori, M. and Yamaguchi, J. (1995) Oligotrophic bacteria isolated from clinical materials. J. Clin. Microbiol. 33, 493-494.
309. Takayama, K. and Kjelleberg, S. (2000) The role of RNA stability during bacterial stress responses and starvation. Environ. Microbiol. 2, 355-365.
310. Tempest, D.W., Herbert, D. and Phipps, P. (1967) Studies on the growth of Aerobacter aerogenes at low dilutions rates in a chemostat. In: Microbial Physiology and Continious Culture (E.O. Powell, C.G. T. Evans, R.E. Strange and D.W. Tempest, eds), pp. 11-22. Her Majesty's Stationery Office, London.
311. Testerman, T.L., Vazquez-Torres, A., Xu, Y., Jones-Carson, J., Libby, S.J. and Fang, F.C. (2002) The alternative sigma factor sigmaE controls antioxidant defences required for Salmonella virulence and stationary-phase survival. Mol. Microbiol. 43, 771-782.
312. Tholozan, J.L., Cappelier, J.M., Tissier, J.P., Delattre, G. and Federighi, M. (1999) Physiological characterisation of viable-but-non-culturable Campylobacter jejuni cells. Appl. Environ. Microbiol. 65, 1110-1116.
313. Thomas, C., Hill, D. and Mabey, M. (2002) Culturability, injury and morphological dynamics of thermophilic Campylobacter spp. within a laboratory-based aquatic model system. J. Appl. Microbiol. 92, 433-442.
314. Torrella, F. and Morita, R. (1981) Microcultural study of bacterial size changes and microcolony and ultramicrocolony formation by heterotrophic bacteria in seawater. Appl. Environ. Microbiol. 41, 518-527.
315. Torsvik, V., Daae, F.L., Sandaa, R.A. and Ovreas, L. (1998) Novel techniques for analysing microbial diversity in natural and perturbed environments. J. Biotechnol. 64, 53-62.
316. Torsvik, V., Salte, K., Sorheim, R. and Goksoyr, J. (1990) Comparison of phenotypic diversity and DNA heterogeneity in a population of soil bacteria. Appl. Environ. Microbiol. 56, 776-781.
317. Torsvik, V., Sorheim, R. and Goksoyr, J. (1996) Total bacterial diversity in soil and sediment communities - a review. J. Ind. Microbiol. 17, 170-178.
318. Trent, J.D., Chastain, R.A. and Yayanos, A.A. (1984) Possible artefactual basis for apparent bacterial growth at 250°C. Nature 307, 737-740.
319. Triger, Y.G. and Polyanskaya, L.M. (1991) Autoregulation of spore germination in Streptomyces grown on rich and poor media. Microbiology (Rus.) 60, 322-325.
320. Troitskaia, V.V., Chetina, E.V., Aliapkina Iu, S., Litvin, V. and Gintsburg, A.L. (1996) Non-culturable forms of Yersinia pseudotuberculosis in the soils of a natural focus of pseudotuberculosis. Zh. Mikrobiol. Epidemiol. Immunobiol. 5, 13-5.
321. Turner, K., Porter, J., Pickup, R. and Edwards, C. (2000) Changes in viability and macromolecular content of long-term batch cultures of Salmonella typhimurium measured by flow cytometry. J. Appl. Microbiol. 89, 90-99.
322. Turpin, P.E., Maycroft, K.A., Rowlands, C.L. and Wellington, E.M. (1993) Viable but non-culturable salmonellas in soil. J. Appl. Bacteriol. 74, 421-427.
323. van Overbeek, L.S., Eberl, L., Givskov, M., Molin, S. and van Elsas, J.D. (1995) Survival of, and induced stress resistance in, carbon-starved Pseudomonas fluorescens cells residing in soil. Appl. Environ. Microbiol. 61, 4202-4208.
324. Varon, M., Cohen, S. and Rosenberg, E. (1984) Autocides produced by Myxococcus xanthus. J. Bacteriol. 160, 1146-1150.
325. Velayati, A.A., Bakayev, V.V. and Bahrmand, A.R. (2002) Use of PCR and culture for detection of Mycobacterium tuberculosis in specimens from patients with normal and slow responses to chemotherapy. Scand. J. Infect. Dis. 34, 163-166.
326. Votyakova, T.V., Kaprelyants, A.S. and Kell, D.B. (1994) Influence of viable cells on the resuscitation of dormant cells in Micrococcus luteus cultures held in an extended stationary phase: the population effect. Appl. Environ. Microbiol. 60, 3284-3291.
327. Vreeland, R.H., Rosenzweig, W.D. and Powers, D.W. (2000) Isolation of a 250 million-year-old halotolerant bacterium from a primary salt crystal. Nature 407, 897-900.
328. Vulic, M. and Kolter, R. (2001) Evolutionary cheating in Escherichia coli stationary phase cultures. Genetics 158, 519-526.
329. Vulic, M. and Kolter, R. (2002) Alcohol-induced delay of viability loss in stationary-phase cultures of Escherichia coli. J. Bacteriol. 184, 2898-2905.
330. Wai, S.N., Mizunoe, Y., Takade, A. and Yoshida, S. (2000) A comparison of solid and liquid media for resuscitation of starvation- and low-temperature-induced non-culturable cells of Aeromonas hydrophila. Arch. Microbiol. 173, 307-310.
331. Wai, S.N., Moriya, T., Kondo, K., Misumi, H. and Amako, K. (1996) Resuscitation of Vibrio cholerae O1 strain TSI-4 from a viable but non-culturable state by heat shock. FEMS Microbiol. Lett. 136, 187-191.
332. Wainwright, M., Barakah, F., al-Turk, I. and Ali, T.A. (1991) Oligotrophic microorganisms in industry, medicine and the environment. Sci. Prog. 75, 313-322.
333. Wang, X., Sturegard, E., Rupar, R., Nilsson, H.O., Aleljung, P.A., Carlen, B., Willen, R. and Wadstrom, T. (1997) Infection of BALB/c A mice by spiral and coccoid forms of Helicobacter pylori. J. Med. Microbiol. 46, 657-663.
334. Ward, D.M., Ferris, M.J., Nold, S.C. and Bateson, M.M. (1998) A natural view of microbial biodiversity within hot spring cyanobacterial mat communities. Microbiol. Mol. Biol. Rev. 62, 1353-1370.
335. Ward, D.M., Weller, R. and Bateson, M.M. (1990) 16S rRNA sequences reveal numerous uncultured microorganisms in a natural community. Nature 345, 63-65.
336. Watson, L. (1987) The Biology of Death (previously published as The Romeo Error). Sceptre Books, London.
337. Watson, S.P., Antonio, M. and Foster, S.J. (1998a) Isolation and characterization of Staphylococcus aureus starvation-induced, stationary-phase mutants defective in survival or recovery. Microbiology UK 144, 3159-3169.
338. Watson, S.P., Clements, M.O. and Foster, S.J. (1998b) Characterization of the starvation-survival response of Staphylococcus aureus. J. Bacteriol. 180, 1750-1758.
339. Wayne, L.G. (1960) The bacteriology of resected tuberculosis pulmonary lesions. II. Observation on bacilli which are stainable but which cannot be cultured. Am. Rev. Respir. Dis. 82, 370-377.
340. Wayne, L.G. (1976) Dynamics of submerged growth of Mycobacterium tuberculosis under aerobic and microaerophilic conditions. Am. Rev. Respir. Dis. 114, 807-811.
341. Wayne, L.G. (1977) Synchronized replication of Mycobacterium tuberculosis. Infect. Immun. 17, 528-530.
342. Wayne, L.G. and Diaz, G.A. (1967) Autolysis and secondary growth of Mycobacterium tuberculosis in submerged culture. J. Bacteriol. 93, 1374-1381.
343. Wayne, L.G. and Sohaskey, C.D. (2001) Non-replicating persistence of Mycobacterium tuberculosis. Annu. Rev. Microbiol. 55, 139-163.
344. Wayne, L.G. and Sramek, H.A. (1994) Metronidazole is bactericidal to dormant cells of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 38, 2054-2058.
345. Weichart, D. and Kjelleberg, S. (1996) Stress resistance and recovery potential of culturable and viable but non-culturable cells of Vibrio vulnificus. Microbiology 142, 845-853.
346. Weichart, D., McDougald, D., Jacobs, D. and Kjelleberg, S. (1997) In situ analysis of nucleic acids in cold-induced non-culturable Vibrio vulnificus. Appl. Environ. Microbiol. 63, 2754-2758.
347. Weichart, D., Oliver, J.D. and Kjelleberg, S. (1992) Low temperature induced non-culturability and killing of Vibrio vulnificus. FEMS Microbiol. Lett. 79, 205-210.
348. Weichart, D.H. and Kell, D.B. (2001) Characterization of an autostimulatory substance produced by Escherichia coli. Microbiology 147, 1875-1885.
349. Whitehead, N.A., Harris, A.K.P., Williams, P. and Salmond, G.P.C. (2002) Quorum sensing in Gram-negitive bacteria: global regulons controlled by cell-density-dependent chemical signalling. In: Signals, Switches, Regulons and Cascades: Control of Bacterial Gene Expression (D.A. Hodgson and C.M. Thomas, eds), pp. 251-287. Cambridge University Press, Cambridge.
350. Whitesides, D.M. and Oliver, J.D. (1997) Resuscitation of Vibrio vulnificus from the viable but non-culturable state. Appl. Environ. Microbiol. 63, 1002-1005.
351. Winson, M.K., Camara, M., Latifi, A., Foglino, M., Chhabra, S.R., Daykin, M., Bally, M., Chapon, V., Salmond, G.P., Bycroft, B.W., Lazdunski, A., Stewart, G.S.A.B., and, Williams, P. and (1995) Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. USA 92, 9427-9231.
352. Wittmann, C. and Heinzle, E. (2001) MALDI-TOF MS for quantification of substrates and products in cultivations of Corynebacterium glutamicum. Biotechnol. Bioeng. 72, 642-647.
353. Wong, D.M., Young-Perkins, K.E. and Merson, R.L. (1988) Factors influencing Clostridium botulinum spore germination, outgrowth, and toxin formation in acidified media. Appl. Environ. Microbiol. 54, 1446-1450.
354. Xu, H.S., Roberts, N., Singleton, F.L., Attwell, R.W., Grimes, D.J., Colwell, R.R. (1982) Survival and viability of non-culturable Escherichia coli and Vibrio cholerae in estuarine and marine environment. Microb. Ecol. 8, 313-323.
355. Yarmolinsky, M.B. (1995) Programmed cell death in bacterial populations. Science 267, 836-837.
356. Young, D.B. and Duncan, K. (1995) Prospects for new interventions in the treatment and prevention of mycobacterial disease. Annu. Rev. Microbiol. 49, 641-673.
357. Zambrano, M.M. and Kolter, R. (1996) GASPing for life in stationary phase. Cell 86, 181-184.
358. Zengler, K., Toledo, G., Rappe, M., Elkins, J., Mathur, E.J., Short, J.M. and Keller, M. (2002). Cultivating the uncultured. Proc Natl Acad Sci USA 99, 15681-15686.
359. Zhang, Y., Yang, Y., Woods, A., Cotter, R.J. and Sun, Z. (2001) Resuscitation of dormant Mycobacterium tuberculosis by phospholipids or specific peptides. Biochem. Biophys. Res. Commun. 284, 542-547.
360. Zinser, E.R. and Kolter, R. (2000) Prolonged stationary-phase incubation selects for lrp mutations in Escherichia coli K-12. J. Bacteriol. 182, 4361-4365.
361. Zweifel, U.L. and Hangstrom, A. (1995) Total counts of marine bacteria include a large fraction of non-nucleoid-containing bacteria (ghosts). Appl. Environ. Microbiol. 61, 2180-2185.