Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3- hydroxycarbonyl-4-hydroxy)-styrylbenzene in strong base: Probes for amyloid plaques in the brain

Journal of Medicinal Chemistry

Volumn 44, Issue 14, 2001, Pages 2270-2275

  Lee, C W ^a   Zhuang, Z P ^a   Kung, M P ^a   Plossl K ^a   Skovronsky, D ^a   Gur, T ^a   Hou, C ^a   Trojanowski, J Q ^a   Lee, V M Y ^a   Kung, H F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 BROMO 2,5 BIS(3 HYDROXYCARBONYL 4 HYDROXY)STYRYLBENZENE; AMYLOID BETA PROTEIN; BENZENE DERIVATIVE; FLUORESCENT DYE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AQUEOUS SOLUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; GEOMETRY; HUMAN; HUMAN TISSUE; ISOMERISM; PROTEIN AGGREGATION; SENILE PLAQUE; SYNTHESIS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; BRAIN; FLUORESCENT DYES; HUMANS; KINETICS; MICROSCOPY, FLUORESCENCE; PEPTIDE FRAGMENTS; SENILE PLAQUES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; STYRENES;

EID: 0035811461     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010161t     Document Type: Article

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