Sorting out self and microbial lipid antigens for CD1

Microbes and Infection

Volumn 5, Issue 12, 2003, Pages 1137-1148

  Roura Mir, Carme ^a   Moody, D Branch ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

CD1; Endosomes; Glycolipid; Mycobacterium tuberculosis; T cells

Indexed keywords

AMINO ACID; ANTIGEN; BETA 2 MICROGLOBULIN; CD1 ANTIGEN; FAS ANTIGEN; GALACTOSYLCERAMIDE; GLUCOSE DERIVATIVE; GLUCOSE MONOMYCOLATE; LIGAND; LIPID; LIPOARABINOMANNAN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MANNOSIDE; PHOSPHATIDYLINOSITOL; PROTEIN SUBUNIT; RECEPTOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGEN FUNCTION; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; APOPTOSIS; B LYMPHOCYTE; BINDING AFFINITY; BONE MARROW CELL; CELL DEATH; CELL MIGRATION; ENDOSOME; FOREIGN BODY; HUMAN; HYPOTHESIS; IMMUNITY; INFECTION; INTERNALIZATION; INTRACELLULAR SPACE; LIPID TRANSPORT; MAJOR HISTOCOMPATIBILITY COMPLEX; MAMMAL CELL; MICROENVIRONMENT; MICROORGANISM; MYCOBACTERIOSIS; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; NATURAL KILLER CELL; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STRUCTURE; REVIEW; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; TUBERCULOSIS;

MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 0141526330     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micinf.2003.08.003     Document Type: Short Survey

References (77)

1. Calabi F., Milstein C. A novel family of human major histocompatibility complex-related genes not mapping to chromosome 6. Nature. 323:1986;540-543.
2. Zeng Z., Castaño A.R., Segelke B.W., Stura E.A., Peterson P.A., Wilson I.A. Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove. Science. 277:1997;339-345.
3. Zajonc D.M., Elsliger M.A., Teyton L., Wilson I.A. Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 Å Nat. Immunol. 4:2003;808-815.
4. Gadola S.D., Zaccai N.R., Harlos K., Shepherd D., Castro-Palomino J.C., Ritter G., Schmidt R.R., Jones E.Y., Cerundolo V. Structure of human CD1b with bound ligands at 2.3 Å, a maze for alkyl chains. Nat. Immunol. 3:2002;721-726.
5. Kawano T., Cui J., Koezuka Y., Toura I., Kaneko Y., Motoki K., Ueno H., Nakagawa R., Sato H., Kondo E., Koseki H., Taniguchi M. CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science. 278:1997;1626-1629.
6. Grant E.P., Degano M., Rosat J.P., Stenger S., Modlin R.L., Wilson I.A., Porcelli S.A., Brenner M.B. Molecular recognition of lipid antigens by T cell receptors. J. Exp. M. 189:1999;195-205.
7. Benlagha K., Weiss A., Beavis A., Teyton L., Bendelac A. In vivo identification of glycolipid antigen-specific T cells using fluorescent CD1d tetramers. J. Exp. M. 191:2000;1895-1903.
8. Matsuda J.L., Naidenko O.V., Gapin L., Nakayama T., Taniguchi M., Wang C.R., Koezuka Y., Kronenberg M. Tracking the response of natural killer T cells to a glycolipid antigen using CD1d tetramers. J. Exp. M. 192:2000;741-754.
9. Melian A., Watts G.F., Shamshiev A., De Libero G., Clatworthy A., Vincent M., Brenner M.B., Behar S., Niazi K., Modlin R.L., Almo S., Ostrov D., Nathenson S.G., Porcelli S.A. Molecular recognition of human CD1b antigen complexes: evidence for a common pattern of interaction with alpha beta TCRs. J. Immunol. 165:2000;4494-4504.
10. Moody D.B., Reinhold B.B., Guy M.R., Beckman E.M., Frederique D.E., Furlong S.T., Ye S., Reinhold V.N., Sieling P.A., Modlin R.L., Besra G.S., Porcelli S.A. Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science. 278:1997;283-286.
11. Porcelli S.A. The CD1 family: a third lineage of antigen-presenting molecules. Adv. Immunol. 59:1995;1-98.
12. Shamshiev A., Gober H.J., Donda A., Mazorra Z., Mori L., De Libero G. Presentation of the same glycolipid by different CD1 molecules. J. Exp. M. 195:2002;1013-1021.
13. Porcelli S., Brenner M.B., Greenstein J.L., Balk S.P., Terhorst C., Bleicher P.A. Recognition of cluster of differentiation 1 antigens by human CD4-CD8-cytolytic T lymphocytes. Nature. 341:1989;447-450.
14. Joyce S., DeSilva A.D., Yewdell J.W., Bennink J.R., Woods A.S., Boesteanu A., Balk S.P., Cotter R.J., Brutkiewicz R.R. Natural ligand of mouse CD1d1: cellular glycosylphosphatidylinositol. Science. 279:1998;1541-1544.
15. De Silva A.D., Park J.J., Matsuki N., Stanic A.K., Brutkiewicz R.R., Medof M.E., Joyce S. Lipid protein interactions: the assembly of CD1d1 with cellular phospholipids occurs in the endoplasmic reticulum. J. Immunol. 168:2002;723-733.
16. Gumperz J.E., Roy C., Makowska A., Lum D., Sugita M., Podrebarac T., Koezuka Y., Porcelli S.A., Cardell S., Brenner M.B., Behar S.M. Murine CD1d-restricted T cell recognition of cellular lipids. Immunity. 12:2000;211-221.
17. Schofield L., McConville M.J., Hansen D., Campbell A.S., Fraser-Reid B., Grusby M.J., Tachado S.D. CD1d-restricted immunoglobulin G formation to GPI-anchored antigens mediated by NKT cells. Science. 283:1999;225-229.
18. Shamshiev A., Donda A., Carena I., Mori L., Kappos L., De Libero G. Self glycolipids as T-cell autoantigens. Eur. J. Immunol. 29:1999;1667-1675.
19. Bendelac A., Lantz O., Quimby M.E., Yewdell J.W., Bennink J.R., Brutkiewicz R.R. CD1 recognition by mouse NK1+ T lymphocytes. Science. 268:1995;863-865.
20. Stanic A.K., De Silva A.D., Park J.J., Sriram V., Ichikawa S., Hirabyashi Y., Hayakawa K., Van Kaer L., Brutkiewicz R.R., Joyce S. Defective presentation of the CD1d1-restricted natural Vα14Jα18 NKT lymphocyte antigen caused by beta-D-glucosylceramide synthase deficiency. Proc. Natl. Acad. Sci. USA. 100:2003;1849-1854.
21. Moody D.B., Besra G.S. Glycolipid targets of CD1-mediated T-cell responses. Immunology. 104:2001;243-251.
22. Porcelli S., Morita C.T., Brenner M.B. CD1b restricts the response of human CD4-8- T lymphocytes to a microbial antigen. Nature. 360:1992;593-597.
23. Beckman E.M., Porcelli S.A., Morita C.T., Behar S.M., Furlong S.T., Brenner M.B. Recognition of a lipid antigen by CD1-restricted alpha beta+ T cells. Nature. 372:1994;691-694.
24. Barry C.E. III, Lee R.E., Mdluli K., Sampson A.E., Schroeder B.G., Slayden R.A., Yuan Y. Mycolic acids: structure, biosynthesis and physiological functions. Prog. Lipid Res. 37:1998;143-179.
25. Sieling P.A., Chatterjee D., Porcelli S.A., Prigozy T.I., Mazzaccaro R.J., Soriano T., Bloom B.R., Brenner M.B., Kronenberg M., Brennan P.J., et al. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science. 269:1995;227-230.
26. Ernst W.A., Maher J., Cho S., Niazi K.R., Chatterjee D., Moody D.B., Besra G.S., Watanabe Y., Jensen P.E., Porcelli S.A., Kronenberg M., Modlin R.L. Molecular interaction of CD1b with lipoglycan antigens. Immunity. 8:1998;331-340.
27. Moody D.B., Ulrichs T., Muhlecker W., Young D.C., Gurcha S.S., Grant E., Rosat J.P., Brenner M.B., Costello C.E., Besra G.S., Porcelli S.A. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection. Nature. 404:2000;884-888.
28. Moody D.B. Polyisoprenyl glycolipids as targets of CD1-mediated T cell responses. Cell Mol. Life Sci. 58:2001;1461-1474.
29. Rosat J.P., Grant E.P., Beckman E.M., Dascher C.C., Sieling P.A., Frederique D., Modlin R.L., Porcelli S.A., Furlong S.T., Brenner M.B. CD1-restricted microbial lipid antigen-specific recognition found in the CD8+ alpha beta T cell pool. J. Immunol. 162:1999;366-371.
30. Fairhurst R.M., Wang C.X., Sieling P.A., Modlin R.L., Braun J. CD1 presents antigens from a gram-negative bacterium, Haemophilus influenzae type B. Infect. Immun. 66:1998;3523-3526.
31. Kumar H., Belperron A., Barthold S.W., Bockenstedt L.K. Cutting edge: CD1d deficiency impairs murine host defense against the spirochete, Borrelia burgdorferi. J. Immunol. 165:2000;4797-4801.
32. Molano A., Park S.H., Chiu Y.H., Nosseir S., Bendelac A., Tsuji M. Cutting edge: the IgG response to the circumsporozoite protein is MHC class II-dependent and CD1d-independent: exploring the role of GPIs in NK T cell activation and antimalarial responses. J. Immunol. 164:2000;5005-5009.
33. Procopio D.O., Almeida I.C., Torrecilhas A.C., Cardoso J.E., Teyton L., Travassos L.R., Bendelac A., Gazzinelli R.T. Glycosylphosphatidylinositol-anchored mucin-like glycoproteins from Trypanosoma cruzi bind to CD1d but do not elicit dominant innate or adaptive immune responses via the CD1d/NKT cell pathway. J. Immunol. 169:2002;3926-3933.
34. Ulrichs T., Moody D.B., Grant E., Kaufmann S.H., Porcelli S.A. T-cell responses to CD1-presented lipid antigens in humans with Mycobacterium tuberculosis infection. Infect. Immun. 71:2003;3076-3087.
35. Stenger S., Mazzaccaro R.J., Uyemura K., Cho S., Barnes P.F., Rosat J.P., Sette A., Brenner M.B., Porcelli S.A., Bloom B.R., Modlin R.L. Differential effects of cytolytic T cell subsets on intracellular infection. Science. 276:1997;1684-1687.
36. Eads J., Sacchettini J.C., Kromminga A., Gordon J.I. Escherichia coli-derived rat intestinal fatty acid binding protein with bound myristate at 1.5 Å resolution and I-FABPArg106→Gln with bound oleate at 1.74 Å resolution. J. Biol. Chem. 268:1993;26375-26385.
37. Moody D.B., Briken V., Cheng T.Y., Roura-Mir C., Guy M.R., Geho D.H., Tykocinski M.L., Besra G.S., Porcelli S.A. Lipid length controls antigen entry into endosomal and nonendosomal pathways for CD1b presentation. Nat. Immunol. 3:2002;435-442.
38. Sugita M., Porcelli S.A., Brenner M.B. Assembly and retention of CD1b heavy chains in the endoplasmic reticulum. J. Immunol. 159:1997;2358-2365.
39. Briken V., Jackman R.M., Dasgupta S., Hoening S., Porcelli S.A. Intracellular trafficking pathway of newly synthesized CD1b molecules. EMBO J. 21:2002;825-834.
40. Jayawardena-Wolf J., Benlagha K., Chiu Y.H., Mehr R., Bendelac A. CD1d endosomal trafficking is independently regulated by an intrinsic CD1d-encoded tyrosine motif and by the invariant chain. Immunity. 15:2001;897-908.
41. Kang S.J., Cresswell P. Regulation of intracellular trafficking of human CD1d by association with MHC class II molecules. EMBO J. 21:2002;1650-1660.
42. Sugita M., van Der Wel N., Rogers R.A., Peters P.J., Brenner M.B. CD1c molecules broadly survey the endocytic system. Proc. Natl. Acad. Sci. USA. 97:2000;8445-8450.
43. Briken V., Jackman R.M., Watts G.F., Rogers R.A., Porcelli S.A. Human CD1b and CD1c isoforms survey different intracellular compartments for the presentation of microbial lipid antigens. J. Exp. M. 192:2000;281-288.
44. Sugita M., Jackman R.M., van Donselaar E., Behar S.M., Rogers R.A., Peters P.J., Brenner M.B., Porcelli S.A. Cytoplasmic tail-dependent localization of CD1b antigen-presenting molecules to MIICs. Science. 273:1996;349-352.
45. Sugita M., Cao X., Watts G.F., Rogers R.A., Bonifacino J.S., Brenner M.B. Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells. Immunity. 16:2002;697-706.
46. Rodionov D.G., Nordeng T.W., Kongsvik T.L., Bakke O. The cytoplasmic tail of CD1d contains two overlapping basolateral sorting signals. J. Biol. Chem. 275:2000;8279-8282.
47. Sugita M., Grant E.P., van Donselaar E., Hsu V.W., Rogers R.A., Peters P.J., Brenner M.B. Separate pathways for antigen presentation by CD1 molecules. Immunity. 11:1999;743-752.
48. Roberts T.J., Sriram V., Spence P.M., Gui M., Hayakawa K., Bacik I., Bennink J.R., Yewdell J.W., Brutkiewicz R.R. Recycling CD1d1 molecules present endogenous antigens processed in an endocytic compartment to NKT cells. J. Immunol. 168:2002;5409-5414.
49. Chiu Y.H., Park S.H., Benlagha K., Forestier C., Jayawardena-Wolf J., Savage P.B., Teyton L., Bendelac A. Multiple defects in antigen presentation and T cell development by mice expressing cytoplasmic tail-truncated CD1d. Nat. Immunol. 3:2002;55-60.
50. Chiu Y.H., Jayawardena J., Weiss A., Lee D., Park S.H., Dautry-Varsat A., Bendelac A. Distinct subsets of CD1d-restricted T cells recognize self-antigens loaded in different cellular compartments. J. Exp. M. 189:1999;103-110.
51. Moody D.B., Reinhold B.B., Reinhold V.N., Besra G.S., Porcelli S.A. Uptake and processing of glycosylated mycolates for presentation to CD1b-restricted T cells. Immunol. Lett. 65:1999;85-91.
52. Jackman R.M., Stenger S., Lee A., Moody D.B., Rogers R.A., Niazi K.R., Sugita M., Modlin R.L., Peters P.J., Porcelli S.A. The tyrosine-containing cytoplasmic tail of CD1b is essential for its efficient presentation of bacterial lipid antigens. Immunity. 8:1998;341-351.
53. Prigozy T.I., Naidenko O., Qasba P., Elewaut D., Brossay L., Khurana A., Natori T., Koezuka Y., Kulkarni A., Kronenberg M. Glycolipid antigen processing for presentation by CD1d molecules. Science. 291:2001;664-667.
54. Sallusto F., Cella M., Danieli C., Lanzavecchia A. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J. Exp. M. 182:1995;389-400.
55. Engering A.J., Cella M., Fluitsma D., Brockhaus M., Hoefsmit E.C., Lanzavecchia A., Pieters J. The mannose receptor functions as a high capacity and broad specificity antigen receptor in human dendritic cells. Eur. J. Immunol. 27:1997;2417-2425.
56. Geijtenbeek T.B., van Vliet S.J., Koppel E.A., Sanchez-Hernandez M., Vandenbroucke-Grauls C.M., Appelmelk B., van Kooyk Y. Mycobacteria target DC-SIGN to suppress dendritic cell function. J. Exp. M. 197:2003;7-17.
57. Tailleux L., Schwartz O., Herrmann J.L., Pivert E., Jackson M., Amara A., Legres L., Dreher D., Nicod L.P., Gluckman J.C., Lagrange P.H., Gicquel B., Neyrolles O. DC-SIGN is the major Mycobacterium tuberculosis receptor on human dendritic cells. J. Exp. M. 197:2003;121-127.
58. Engering A., Geijtenbeek T.B., van Vliet S.J., Wijers M., van Liempt E., Demaurex N., Lanzavecchia A., Fransen J., Figdor C.G., Piguet V., van Kooyk Y. The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells. J. Immunol. 168:2002;2118-2126.
59. Prigozy T.I., Sieling P.A., Clemens D., Stewart P.L., Behar S.M., Porcelli S.A., Brenner M.B., Modlin R.L., Kronenberg M. The mannose receptor delivers lipoglycan antigens to endosomes for presentation to T cells by CD1b molecules. Immunity. 6:1997;187-197.
60. Sturgill-Koszycki S., Schlesinger P.H., Chakraborty P., Haddix P.L., Collins H.L., Fok A.K., Allen R.D., Gluck S.L., Heuser J., Russell D.G. Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science. 263:1994;678-681.
61. Ferrari G., Langen H., Naito M., Pieters J. A coat protein on phagosomes involved in the intracellular survival of mycobacteria. Cell. 97:1999;435-447.
62. Fratti R.A., Backer J.M., Gruenberg J., Corvera S., Deretic V. Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. J. Cell Biol. 154:2001;631-644.
63. Trombetta E.S., Ebersold M., Garrett W., Pypaert M., Mellman I. Activation of lysosomal function during dendritic cell maturation. Science. 299:2003;1400-1403.
64. Fischer K., Chatterjee D., Torrelles J., Brennan P.J., Kaufmann S.H., Schaible U.E. Mycobacterial lysocardiolipin is exported from phagosomes upon cleavage of cardiolipin by a macrophage-derived lysosomal phospholipase A2. J. Immunol. 167:2001;2187-2192.
65. Fadok V.A., Bratton D.L., Henson P.M. Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences. J. Clin. Invest. 108:2001;957-962.
66. Albert M.L., Sauter B., Bhardwaj N. Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs. Nature. 392:1998;86-89.
67. Liu K., Iyoda T., Saternus M., Kimura Y., Inaba K., Steinman R.M. Immune tolerance after delivery of dying cells to dendritic cells in situ. J. Exp. M. 196:2002;1091-1097.
68. Xu S., Cooper A., Sturgill-Koszycki S., van Heyningen T., Chatterjee D., Orme I., Allen P., Russell D.G. Intracellular trafficking in Mycobacterium tuberculosis and Mycobacterium avium-infected macrophages. J. Immunol. 153:1994;2568-2578.
69. Lemassu A., Daffe M. Structural features of the exocellular polysaccharides of Mycobacterium tuberculosis. Biochem. J. 297:(Pt 2):1994;351-357.
70. Schaible U.E., Hagens K., Fischer K., Collins H.L., Kaufmann S.H. Intersection of group I CD1 molecules and mycobacteria in different intracellular compartments of dendritic cells. J. Immunol. 164:2000;4843-4852.
71. Beatty W.L., Rhoades E.R., Ullrich H.J., Chatterjee D., Heuser J.E., Russell D.G. Trafficking and release of mycobacterial lipids from infected macrophages. Traffic. 1:2000;235-247.
72. Thery C., Zitvogel L., Amigorena S. Exosomes: composition, biogenesis and function. Nat. Rev. Immunol. 2:2002;569-579.
73. Bendelac A. Positive selection of mouse NK1+ T cells by CD1-expressing cortical thymocytes. J. Exp. M. 182:1995;2091-2096.
74. Small T.N., Knowles R.W., Keever C., Kernan N.A., Collins N., O'Reilly R.J., Dupont B., Flomenberg N. M241 (CD1) expression on B lymphocytes. J. Immunol. 138:1987;2864-2868.
75. Sieling P.A., Porcelli S.A., Duong B.T., Spada F., Bloom B.R., Diamond B., Hahn B.H. Human double-negative T cells in systemic lupus erythematosus provide help for IgG and are restricted by CD1c. J. Immunol. 165:2000;5338-5344.
76. Guermonprez P., Valladeau J., Zitvogel L., Thery C., Amigorena S. Antigen presentation and T cell stimulation by dendritic cells. Annu. Rev. Immunol. 20:2002;621-667.
77. Sieling P.A., Jullien D., Dahlem M., Tedder T.F., Rea T.H., Modlin R.L., Porcelli S.A. CD1 expression by dendritic cells in human leprosy lesions: correlation with effective host immunity. J. Immunol. 162:1999;1851-1858.