Molecular recognition of lipid antigens by T cell receptors

Journal of Experimental Medicine

Volumn 189, Issue 1, 1999, Pages 195-205

  Grant, Ethan P ^a   Degano, Massimo ^b   Rosat, Jean Pierre ^a   Stenger, Steffen ^c   Modlin, Robert L ^c   Wilson, Ian A ^b   Porcelli, Steven A ^a   Brenner, Michael B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Antigen presentation; CD1; Mycobacterium tuberculosis; Mycolic acid; T cell receptor

Indexed keywords

AMINO ACID; ANTIGEN; CD1 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MYCOLIC ACID; NUCLEOTIDE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; COMPLEMENTARITY DETERMINING REGION; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIGENS; ANTIGENS, CD1; CLONE CELLS; CLONING, MOLECULAR; HUMANS; LIPIDS; MICE; MODELS, MOLECULAR; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; TRANSFECTION;

EID: 0033521664     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.189.1.195     Document Type: Article

References (39)

1. Allison, J.P., L. Ridge, J. Lund, J. Gross-Pelose, L. Lanier, and B.W. McIntyre. 1984. The murine T cell antigen receptor and associated structures. Immunol. Rev. 81:145-160.
2. Haskins, K., J. Kappler, and P. Marrack. 1984. The major histocompatibility complex-restricted antigen receptor on T cells. Annu. Rev. Immunol. 2:51-66.
3. Meuer, S.C., O. Acuto, T. Hercend, S.F. Schlossman, and E.L. Reinherz. 1984. The human T-cell receptor. Annu. Rev. Immunol. 2:23-50.
4. + T cells. Nature. 372: 691-694.
5. Beckman, E.M., A. Melian, S.M. Behar, P.A. Sieling, D. Chatterjee, S.T. Furlong, R. Matsumoto, J.P. Rosat, R.L. Modlin, and S.A. Porcelli. 1996. CD1c restricts responses of mycobacteria-specific T cells - evidence for antigen presentation by a second member of the human CD1 family. J. Immunol. 157:2795-2803.
6. Moody, D.B., B.B. Reinhold, M.R. Guy, E.M. Beckman, D.E. Frederique, S.T. Furlong, S. Ye, V.N. Reinhold, P.A. Sieling, R.L. Modlin, et al. 1997. Structural requirements for glycolipid antigen recognition by CD1b-restricted T cells. Science. 278:283-286.
7. Sieling, P.A., D. Chatterjee, S.A. Porcelli, T.I. Prigozy, R.J. Mazzaccaro, T. Soriano, B.R. Bloom, M.B. Brenner, M. Kronenberg, P.J. Brennan, and R.L. Modlin. 1995. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science. 269:227-230.
8. Porcelli, S.A. 1995. The CD1 family: a third lineage of antigen-presenting molecules. Adv. Immunol. 59:1-98.
9. Zeng, Z.-H., A.R. Castãno, B.W. Segelke, E.A. Stura, P.A. Peterson, and I.A. Wilson. 1997. Crystal structure of mouse CD1: an MHC-like fold with a large hydrophobic binding groove. Science. 277:339-345.
10. Ernst, W.A., J. Maher, S.G. Cho, K.R. Niazi, D. Chatterjee, D.B. Moody, G.S. Besra, Y. Watanabe, P.E. Jensen, S.A. Porcelli, et al. 1998. Molecular interaction of CDIb with lipoglycan antigens. Immunity. 8:331-340.
11. Joyce, S., A.S. Woods, J.W. Yewdell, J.R. Bennink, A.D. Desilva, A. Boesteanu, S.P. Balk, R.J. Cotter, and R.R. Brutkiewicz. 1998. Natural ligand of mouse CD1d1-cellular glycosylphosphatidylinositol. Science. 279:1541-1544.
12. Davodeau, F., M.A. Peyrat, A. Necker, R. Dominici, F. Blanchard, C. Leget, J. Gaschet, P. Costa, Y. Jacques, A. Godard, et al. 1997. Close phenotypic and functional similarities between human and murine αβ T cells expressing invariant TCR α-chains. J. Immunol. 158:5603-5611.
13. - T cells. J. Exp. Med. 186:109-120.
14. Stenger, S., R.J. Mazzaccaro, K. Uyemura, S. Cho, P.F. Barnes, J.P. Rosat, A. Sette, M.B. Brenner, S.A. Porcelli, B.R. Bloom, and R.L. Modlin. 1997. Differential effects of cytolytic T cell subsets on intracellular infection. Science. 276: 1684-1687.
15. - T lymphocytes to a microbial antigen. Nature. 360:593-597.
16. Panchamoorthy, G., J. McLean, R.L. Modlin, C.T. Morita, S. Ishikawa, M.B. Brenner, and H. Band. 1991. A predominance of the T cell receptor Vγ2/Vδ2 subset in human mycobacteria-responsive T cells suggests germline gene encoded recognition. J. Immunol. 147:3360-3369.
17. Olive, D., P. Dubreuil, and C. Mawas. 1984. Two distinct TL-like molecular subsets defined by monoclonal antibodies on the surface of human thymocytes with different expression on leukemia lines. Immunogenetics. 20:253-264.
18. - T cells: B7-independent costimulation of CD1-restricted T cells. J. Exp. Med. 182:2007-2018.
19. Spits, H., G. Keizer, J. Borst, C. Terhorst, A. Hekman, and J.E. de Vries. 1983. Characterization of monoclonal antibodies against cell surface molecules associated with cytotoxic activity of natural and activated killer cells and cloned CTL lines. Hybridoma, 2:423-437.
20. + αβ T cell pool. J. Immunol. 162:366-371.
21. + T cell expansions in the peripheral blood of rheumatoid arthritis patients. J. Exp. Med. 177:1623-1631.
22. Uematsu, Y. 1991. A novel and rapid cloning method for the T-cell receptor variable region sequences. Immunogenetics. 34: 174-178.
23. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal. Biochem. 162:156-159.
24. Brawley, J.V., and P. Concannon. 1996. Modulation of promiscuous T cell receptor recognition by mutagenesis of CDR2 residues. J. Exp. Med. 183:2043-2051.
25. Jones, T.A., J.Y. Zou, S.W. Cowan, and M. Kjeldgaard. 1991. Improved methods for binding protein models in electron density maps and the location of errors in these models. Acta Crystallogr. A. 47:110-119.
26. Jones, T.A., and S. Thirup. 1986. Using known substructures in protein model building and crystallography. EMBO (Eur. Mol. Biol. Organ.) J. 5:819-822.
27. Brunger, A.T. 1992. X-PLOR Version 3.1: A System for X-ray and NMR. Yale University Press, New Haven, CT. 382 pp.
28. Garcia, K.C., M. Degano, R.L. Stanfield, A. Brunmark, M.R. Jackson, P.A. Peterson, L. Teyton, and I.A. Wilson. 1996. An αβ T cell receptor structure at 2.5 Angstrom and its orientation in the TCR-MHC complex. Science. 274: 209-219.
29. Garboczi, D.N., P. Ghosh, U. Utz, Q.R. Fan, W.E. Biddison, and D.C. Wiley. 1996. Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 384:134-141.
30. Housset, D., G. Mazza, C. Gregoire, C. Piras, B. Malissen, and J.C. Fontecilla-Camps. 1997. The three-dimensional structure of a T-cell antigen receptor Vα Vβ heterodimer reveals a novel arrangement of the Vβ domain. EMBO (Eur. Mol. Biol. Organ.) J. 16:4205-4216.
31. Wang, J., K. Lim, A. Smolyar, M. Teng, J. Liu, A.G. Tse, R.E. Hussey, Y. Chishti, C.T. Thomson, R.M. Sweet, et al. 1998. Atomic structure of an αβ T cell receptor (TCR) heterodimer in complex with an anti-TCR Fab fragment derived from a mitogenic antibody. EMBO (Eur. Mol. Biol. Organ.) J. 17:10-26.
32. Garcia, K.C., M. Degano, L.R. Pease, M.D. Huang, P.A. Peterson, L. Teyton, and I.A. Wilson. 1998. Structural basis of plasticity in T cell receptor recognition of a self peptide MHC antigen. Science. 279:1166-1172.
33. Laskowski, R.A., M.W. MacArthur, D.S. Moss, and J.M. Thornton. 1993. A program to check the stereochemical quality of protein structures. J. Appl. Cryst. 26:183-191.
34. Ferrin, T.E., C.C. Huang, L.E. Jarvis, and R. Langridge. 1988. The MIDAS display system. J. Mol. Graph. 6:13-27.
35. Altschul, S.F., W. Gish, W. Miller, E.W. Myers, and D.J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
36. Zeng, D.F., M. Dick, L.R. Cheng, M. Amano, S. Dejbakhshjones, P. Huie, R. Sibley, and S. Strober. 1998. Subsets of transgenic T cells that recognize CD1 induce or prevent murine lupus: role of cytokines. J. Exp. Med. 187:525-536.
37. -α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain J. Exp. Med. 178:1-16.
38. Bendelac, A., M.N. Rivera, S.H. Park, and J.H. Roark. 1997. Mouse CD1-specific NK1 T cells: development, specificity, and function. Annu. Rev. Immunol. 15:535-562.
39. Balk, S.P., E.C. Ebert, R.L. Blumenthal, F.V. McDermott, K.W. Wucherpfennig, S.B. Landau, and R.S. Blumberg. 1991. Oligoclonal expansion and CD1 recognition by human intestinal intraepithelial lymphocytes. Science. 253:1411-1415.