Cutting edge: CD1d deficiency impairs murine host defense against the spirochete, Borrelia burgdorferi

Journal of Immunology

Volumn 165, Issue 9, 2000, Pages 4797-4801

  Kumar, H ^a   Belperron, A ^a   Barthold, S W ^a   Bockenstedt, L K ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD1 ANTIGEN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN EXPRESSION; ARTICLE; BORRELIA BURGDORFERI; BORRELIA INFECTION; CONTROLLED STUDY; HOST RESISTANCE; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY;

EID: 0034327173     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.9.4797     Document Type: Article

References (41)

1. The CD1 system: Antigen-presenting molecules for T cell recognition of lipids and glycolipids
2. Natural ligand of mouse CD1d1: Cellular glycosylphosphatidylinositol
3. CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides
4. Presentation of bacterial lipid antigens by CD1 molecules
5. Murine CD1d-restricted T cell recognition of cellular lipids
6. CD1c-mediated T-cell recognition of isoprenoid glycolipids in Mycobacterium tuberculosis infection
7. + effector function against intracellular infection
8. Murine natural killer T (NKT) cells contribute to the granulomatous reaction caused by mycobacterial cell walls
9. Anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF-β2 and Th1 cytokines and meliorates Listeriosis in mice
10. Participation of group 2 CD1 molecules in the control of murine tuberculosis
11. α-Galactosylceramide-activated Vα14 natural killer T cells mediate protection against murine malaria
12. CD1.1 expression by mouse antigen-presenting cells and marginal zone B cells
13. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells
14. + T cell development and early IL-4 production in CD1-deficient mice
15. CD1d1 mutant mice are deficient in natural T cells that promptly produce IL-4
16. 2-microglobulin-dependent and independent forms
17. Splenic dependence of the antibody resonse to thymus-independent (TI-2) antigens
18. Human immune response to pneumococcal polysaccharides: Complement-mediated localization preferentially on CD21-positive splenic marginal zone B cells and follicular dendritic cells
19. Protective and arthritis-resolving activity in serum of mice infected with Borrelia burgdorferi
20. Normal human B lymphocytes and mononuclear cells respond to the mitogenic and cytokine stimulatory activities of Borrelia burgdorferi and its lipoprotein Osp A
21. Protective antibodies in murine Lyme disease arise independently of CD40 ligand
22. + T cells
23. Immunity to Lyme disease: Protection, pathology and persistence
24. Analysis of the lipidated recombinant outer surface protein A from Borrelia burgdorferi by mass spectrometry
25. + intestinal intraepithelial lymphocytes in the absence of both classical MHC class I and non classical CD1 molecules
26. Chronic Lyme borreliosis in the laboratory mouse
27. Lyme borreliosis in selected strains and ages of laboratory mice
28. Quantitative detection of Borrelia burgdorferi with a microtiter-based competitive PCR assay
29. Modulation of murine Lyme borreliosis by interruption of the B7/CD28 T cell costimulatory pathway
30. Inability of truncated recombinant Osp A proteins to elicit protective immunity to Borrelia burgdorferi in mice
31. Evasion of protective immunity by Borrelia burgdorferi by truncation of outer surface protein B
32. Active and passive immunity against Borrelia burgdorferi decorin binding protein A (DbpA) protects against infection
33. Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: Exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease
34. Molecular mapping of OspA-mediated protection against Borrelia burgdorferi, the Lyme disease agent
35. Lyme borreliosis in genetically resistant and susceptible mice with severe combined immunodeficiency
36. Experimental Borrelia burgdorferi infection in inbred mouse strains: Antibody response and association of H-2 genes with resistance and susceptibility to development of arthritis
37. Structural features of Borrelia burgdorferi - The Lyme disease spirochete: Silver staining for nucleic acids
38. Identification of quantitative trait loci governing arthritis severity and humoral responses in the murine model of Lyme disease
39. Circumvention of outer surface protein A immunity by host-adapted Borrelia burgdorferi
40. T cell-mediated pathology in murine Lyme borreliosis
41. Control of early viral and bacterial distribution and disease by natural antibodies