Cytoplasmic tail-dependent localization of CD1b antigen-presenting molecules to MIICs

Science

Volumn 273, Issue 5273, 1996, Pages 349-352

  Sugita, Masahiko ^a   Jackman, Robin M ^a   Van Donselaar, Elly ^b   Behar, Samuel M ^a   Rogers, Rick A ^c   Peters, Peter J ^b   Brenner, Michael B ^a   Porcelli, Steven A ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UTRECHT UNIVERSITY   (Netherlands)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN PRESENTATION; ARTICLE; CYTOPLASM; ENDOCYTOSIS; ENDOSOME; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; PRIORITY JOURNAL;

EID: 0030006882     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.273.5273.349     Document Type: Article

References (34)

1. S. Porcelli et al., Nature 341, 447 (1989); S. Porlli, C. T. Morita, M. B. Brenner, ibid. 360, 593 (1992); E. M. Beckman et al., ibid. 372, 691 (1994).
2. S. Porcelli et al., Nature 341, 447 (1989); S. Porlli, C. T. Morita, M. B. Brenner, ibid. 360, 593 (1992); E. M. Beckman et al., ibid. 372, 691 (1994).
3. S. Porcelli et al., Nature 341, 447 (1989); S. Porlli, C. T. Morita, M. B. Brenner, ibid. 360, 593 (1992); E. M. Beckman et al., ibid. 372, 691 (1994).
4. P. A. Sieling et al., Science 269, 227 (1995); A. Bendelac, ibid., p. 185.
5. P. A. Sieling et al., Science 269, 227 (1995); A. Bendelac, ibid., p. 185.
6. S. A. Poroelli, Adv. Immunol. 59, 1 (1995).
7. M. Sugita, unpublished observations.
8. P. J. Peters, J. J. Neefjes, V. Oorschot, H. L. Ploegh, H. J. Geuze, Nature 349, 669 (1991); P. J. Peters et al., J. Exp. Med. 182, 325 (1995).
9. P. J. Peters, J. J. Neefjes, V. Oorschot, H. L. Ploegh, H. J. Geuze, Nature 349, 669 (1991); P. J. Peters et al., J. Exp. Med. 182, 325 (1995).
10. A. Tulp, D. Verwoerd, B. Dobberstein, H. L. Ploegh, J. Pieters, Nature 369, 120 (1994).
11. F. Sanderson et al., Science 266, 1566 (1994).
12. H. W. Nijman et al., J. Exp. Med. 182, 163 (1995).
13. M. Sugita, P. J. Peters, S. A. Porcelli, unpublished observations.
14. A. Aruffo and B. Seed, J. Immunol. 143, 1723 (1989); S. P. Balk, P. A. Bleicher, C. Terhorst, Proc. Natl. Acad. Sci. U.S.A. 86, 252 (1989).
15. A. Aruffo and B. Seed, J. Immunol. 143, 1723 (1989); S. P. Balk, P. A. Bleicher, C. Terhorst, Proc. Natl. Acad. Sci. U.S.A. 86, 252 (1989).
16. I.V. Sandoval and O. Bakke, Trends Cell Biol. 4, 292 (1994); F. Letoumeur and R. D. Klausner, Cell 69, 1143 (1992).
17. I.V. Sandoval and O. Bakke, Trends Cell Biol. 4, 292 (1994); F. Letoumeur and R. D. Klausner, Cell 69, 1143 (1992).
18. M. S. Marks et al., J. Cell Biol. 131, 351 (1995).
19. C. Harter and I. Mellman, J. Cell Biol. 117, 311 (1992); J. S. Humphrey, P. J. Peters, L. C. Yuan, J. S. Bonifacino, ibid. 120, 1123 (1993); S. Höning and W. Hunziker, ibid. 128, 321 (1995); P. Voorhees et al., EMBO J. 14, 4961 (1995).
20. C. Harter and I. Mellman, J. Cell Biol. 117, 311 (1992); J. S. Humphrey, P. J. Peters, L. C. Yuan, J. S. Bonifacino, ibid. 120, 1123 (1993); S. Höning and W. Hunziker, ibid. 128, 321 (1995); P. Voorhees et al., EMBO J. 14, 4961 (1995).
21. C. Harter and I. Mellman, J. Cell Biol. 117, 311 (1992); J. S. Humphrey, P. J. Peters, L. C. Yuan, J. S. Bonifacino, ibid. 120, 1123 (1993); S. Höning and W. Hunziker, ibid. 128, 321 (1995); P. Voorhees et al., EMBO J. 14, 4961 (1995).
22. C. Harter and I. Mellman, J. Cell Biol. 117, 311 (1992); J. S. Humphrey, P. J. Peters, L. C. Yuan, J. S. Bonifacino, ibid. 120, 1123 (1993); S. Höning and W. Hunziker, ibid. 128, 321 (1995); P. Voorhees et al., EMBO J. 14, 4961 (1995).
23. Complementary DNA for CD1b-TD was generated by polymerase chain reaction with the use of full-length CD1 b cDNA (1) as a template DNA. The primers used were 5′-AGCGGATCCAGTGAACATGCCTTCCAGGGG-3′ (plus strand, 5′ end of CD1b cDNA) and 5′-TCGGGATCCTAGCGCCTCATATACCATAA-3′ (minus strand, 3′ end). The amplified fragment was sequenced and subcloned into pSRα-neo for transfection into HeLa cells. The cytoplasmic amino acid sequences of CD1b-FL and CD1b-TD are Met-Arg-Arg-Arg-Ser-Tyr-Gln-Asn-Ile-Pro and Met-Arg-Arg, respectively.
24. M. A. Williams and M. Fukuda, J. Cell Biol. 111, 955 (1990).
25. R. A. Rogers, R. M. Jack, S. T. Furlong, J. Cell Sci. 106, 485 (1993).
26. H. Ohno et al., Science 269, 1872 (1995).
27. P. G. Lerch, M. van de Rijn, P. Schrier, C. Terhorst, Hum. Immunol. 6, 13 (1983).
28. V. Lotteau et al., Nature 348, 600 (1990); O. Bakke and B. Dobberstein, Cell 63, 707 (1990).
29. V. Lotteau et al., Nature 348, 600 (1990); O. Bakke and B. Dobberstein, Cell 63, 707 (1990).
30. M. Sugita and M. B. Brenner, J. Biol. Chem. 270, 1443 (1995).
31. D. Olive, P. Dubreuil, C. Mawas, Immunogenetics 20, 253 (1984).
32. -) C1R cells. For each immunolabeling, at least 2000 cells were evaluated.
33. L. K. Denzin, N. F. Robbins, C. Carboy-Newcomb, P. Cresswell, Immunity 1, 595 (1994).
34. We thank H. Ploegh, J. Trowsdale, M. Fukuda, P. Cresswell, D. Olive, C. Mawas, V. Hsu, and W. Brown for their gifts of reagents; L. Glimcher of Harvard Medical School for the gift of expression vector p3-9; Genetics Institute (Cambridge, MA) for GMCSF; Schering-Plough Corp. (Kenilworth, NJ) for IL-4; and V. Hsu for critically reading the manuscript. Supported by grants from NIH.