Biophysical Characterization of the Cocaine Binding Pocket in the Serotonin Transporter Using a Fluorescent Cocaine Analogue as a Molecular Reporter

Journal of Biological Chemistry

Volumn 276, Issue 7, 2001, Pages 4717-4723

  Rasmussen, Søren G F ^a   Carroll, F Ivy ^b   Maresch, Martin J ^b   Jensen, Anne Dam ^a   Tate, Christopher G ^c   Gether, Ulrik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b RTI INTERNATIONAL   (United States)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANISOTROPY; CARBOXYLIC ACIDS; ESTERS; FLUORESCENCE; HYDROPHOBICITY; POTASSIUM COMPOUNDS; PROTEINS; PURIFICATION;

COCAINE BINDING POCKET;

BIOCHEMISTRY;

CITALOPRAM; COCAINE; COCAINE DERIVATIVE; ETHANOLAMINE DERIVATIVE; G PROTEIN COUPLED RECEPTOR; NITROBENZENE DERIVATIVE; POTASSIUM IODIDE; SEROTONIN; SEROTONIN TRANSPORTER; TEMPOL; 3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; 8 METHYL 3 (4 METHYLPHENYL)TROPANE 2 CARBOXYLIC ACID N METHYL N (4 NITROBENZO 2 OXA 1,3 DIAZOL 7 YL)ETHANOLAMINE ESTER; 8-METHYL-3-(4-METHYLPHENYL)TROPANE--2-CARBOXYLIC ACID N-METHYL-N-(4-NITROBENZO-2-OXA-1,3-DIAZOL-7-YL)ETHANOLAMINE ESTER; CARRIER PROTEIN; DRUG DERIVATIVE; FLUORESCENT DYE; MEMBRANE PROTEIN; NERVE PROTEIN; RECOMBINANT PROTEIN; SLC6A4 PROTEIN, RAT;

ANIMAL CELL; ANISOTROPY; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPETITIVE INHIBITION; CONTROLLED STUDY; FLUORESCENCE; INSECT CELL; NONHUMAN; PRIORITY JOURNAL; SPECTRAL SENSITIVITY; STEADY STATE; SYNTHESIS; ANIMAL; ARMYWORM; GENETIC TRANSFECTION; GENETICS; METABOLISM; PROTEIN BINDING; RAT; SPECTROFLUOROMETRY;

ANIMALIA; INSECTA;

ANIMALS; BINDING SITES; CARRIER PROTEINS; CITALOPRAM; COCAINE; FLUORESCENT DYES; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; PROTEIN BINDING; RATS; RECOMBINANT PROTEINS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SPECTROMETRY, FLUORESCENCE; SPODOPTERA; TRANSFECTION;

EID: 0035895969     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008067200     Document Type: Article

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