Dendritic cells are responsible for the capacity of CpG oligodeoxynucleotides to act as an adjuvant for protective vaccine immunity against Leishmania major in mice

Journal of Experimental Medicine

Volumn 198, Issue 2, 2003, Pages 281-291

  Shah, Javeed A ^a   Darrah, Patricia A ^a   Ambrozak, David K ^a   Turon, Tara N ^a   Mendez, Susana ^a   Kirman, Joanna ^a   Wu, Chang You ^a   Glaichenhaus, Nicolas ^b   Seder, Robert A ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Leishmania major; Plasmacytoid dendritic cell; Th1 cells; Toll like receptor; Vaccine

Indexed keywords

CD11 ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 12; OLIGODEOXYNUCLEOTIDE; PARASITE ANTIGEN; PROTEIN P70;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVITY; CELL COUNT; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; FEMALE; IMMUNIZATION; IN VIVO STUDY; INFECTION PREVENTION; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, CD11C; ANTIGENS, PROTOZOAN; BASE SEQUENCE; DENDRITIC CELLS; DINUCLEOSIDE PHOSPHATES; FEMALE; IMMUNOTHERAPY, ADOPTIVE; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; MICE; MICE, INBRED BALB C; OLIGODEOXYRIBONUCLEOTIDES; VACCINES;

EID: 0043163724     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20030645     Document Type: Article

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