Methylated Trivalent Arsenicals as Candidate Ultimate Genotoxic Forms of Arsenic: Induction of Chromosomal Mutations but Not Gene Mutations

Environmental and Molecular Mutagenesis

Volumn 42, Issue 3, 2003, Pages 192-205

  Kligerman, Andrew D ^a   Doerr, Carolyn L ^a   Tennant, Alan H ^a   Harrington Brock, Karen ^a   Allen, James W ^a   Winkfield, Ernest ^a   Poorman Allen, Patricia ^b   Kundu, Bijit ^c   Funasaka, Kunihiro ^d   Roop, Barbara C ^a   Mass, Marc J ^a   DeMarini, David M ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b GLAXOSMITHKLINE   (United States)

^c University of North Carolina at Chapel Hill   (United States)

^d OSAKA CITY INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENTAL SCIENCES   (Japan)

Author keywords

Arsenic; Chromosome aberrations; DMAIII; Human lymphocytes; MMA III; Mouse lymphoma; Mutagenicity; Prophage induction; Salmonella; Sister chromatid exchanges

Indexed keywords

CACODYLIC ACID; CLASTOGEN; DIMETHYLARSINOUS ACID; METHANEARSONIC ACID; MONOMETHYLARSONOUS ACID; MUTAGENIC AGENT; ORGANOARSENIC DERIVATIVE; UNCLASSIFIED DRUG;

ANEUPLOIDY; ANIMAL CELL; ARTICLE; CELL METABOLISM; CHROMOSOME ABERRATION; CONTROLLED STUDY; CYTOTOXICITY; ESCHERICHIA COLI; GENE MUTATION; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOMA CELL; MOUSE; MUTAGENICITY; NONHUMAN; PERIPHERAL LYMPHOCYTE; PROPHAGE; SALMONELLA; SISTER CHROMATID EXCHANGE;

ARSENICALS; CHROMOSOME ABERRATIONS; DNA DAMAGE; HUMANS; LYMPHOCYTES; METHYLATION; MUTAGENS; MUTATION; SALMONELLA;

ANIMALIA; ESCHERICHIA COLI; SALMONELLA;

EID: 0042984067     PISSN: 08936692     EISSN: None     Source Type: Journal    
DOI: 10.1002/em.10192     Document Type: Article

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