메뉴 건너뛰기




Volumn 14, Issue 1, 1999, Pages 5-22

Evaluation of the mouse lymphoma tk assay (microwell method) as an alternative to the in vitro chromosomal aberration test

Author keywords

[No Author keywords available]

Indexed keywords

CLASTOGEN; POISON; SOLVENT; THYMIDINE KINASE; TRIFLURIDINE;

EID: 0032949360     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/14.1.5     Document Type: Article
Times cited : (112)

References (107)
  • 2
    • 0020062548 scopus 로고
    • Mutagenic evaluation of carcinogens in the L5178Y/TK assay utilizing postmitochondrial fractions (S9) from normal rat liver
    • Amacher, D.E. and Turner, G.N. (1982) Mutagenic evaluation of carcinogens in the L5178Y/TK assay utilizing postmitochondrial fractions (S9) from normal rat liver. Mutat. Res., 97, 49-65.
    • (1982) Mutat. Res. , vol.97 , pp. 49-65
    • Amacher, D.E.1    Turner, G.N.2
  • 3
    • 0021272670 scopus 로고
    • Mutagenic activity of some clastogenic chemicals at the hypoxanthine guanine phosphoribosyl transferase locus of Chinese hamster ovary cells
    • Amacher, D.E. and Zelljadt, I. (1984) Mutagenic activity of some clastogenic chemicals at the hypoxanthine guanine phosphoribosyl transferase locus of Chinese hamster ovary cells. Mutat. Res., 136, 137-145.
    • (1984) Mutat. Res. , vol.136 , pp. 137-145
    • Amacher, D.E.1    Zelljadt, I.2
  • 4
    • 0017979814 scopus 로고
    • The bacterial mutation test
    • Anderson, D. and Styles, J.A. (1978) The bacterial mutation test. Br. J. Cancer, 37, 924-930.
    • (1978) Br. J. Cancer , vol.37 , pp. 924-930
    • Anderson, D.1    Styles, J.A.2
  • 7
    • 0027406601 scopus 로고
    • The influence of chemical structure on the extent and sites of carcinogenesis for 522 rodent carcinogens and 55 different human carcinogen exposure
    • Ashby, J. and Paton, D. (1993) The influence of chemical structure on the extent and sites of carcinogenesis for 522 rodent carcinogens and 55 different human carcinogen exposure. Mutat. Res., 286, 3-74.
    • (1993) Mutat. Res. , vol.286 , pp. 3-74
    • Ashby, J.1    Paton, D.2
  • 9
    • 0018833324 scopus 로고
    • Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolic systems
    • Bartsch, H. et al. (1980) Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolic systems. Mutat. Res., 76, 1-50.
    • (1980) Mutat. Res. , vol.76 , pp. 1-50
    • Bartsch, H.1
  • 10
    • 0026797870 scopus 로고
    • Effect of sampling time on chromosome aberration yield for 7 chemicals in Chinese hamster ovary cells
    • Bean, C.L., Armstrong, M.J. and Galloway, S.M. (1992) Effect of sampling time on chromosome aberration yield for 7 chemicals in Chinese hamster ovary cells. Mutat. Res., 265, 31-44.
    • (1992) Mutat. Res. , vol.265 , pp. 31-44
    • Bean, C.L.1    Armstrong, M.J.2    Galloway, S.M.3
  • 11
    • 0024443952 scopus 로고
    • Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: Comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control culture
    • Blazak, B.F., Los, F.J., Rudd, C.J. and Caspary, W.J. (1989) Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control culture. Mutat. Res., 224, 197-208.
    • (1989) Mutat. Res. , vol.224 , pp. 197-208
    • Blazak, B.F.1    Los, F.J.2    Rudd, C.J.3    Caspary, W.J.4
  • 12
    • 0018643050 scopus 로고
    • The mutagenic activity of 61 agents as determined by the micronucleus, Salmonella, and sperm abnormality assay
    • Bruce, W.R. and Heddle, J.A. (1979) The mutagenic activity of 61 agents as determined by the micronucleus, Salmonella, and sperm abnormality assay. Can. J. Genet. Cytol., 21, 319-333.
    • (1979) Can. J. Genet. Cytol. , vol.21 , pp. 319-333
    • Bruce, W.R.1    Heddle, J.A.2
  • 13
    • 0027362657 scopus 로고
    • Perspective on the usefulness of the mouse lymphoma assay as an indicator of a genotoxic carcinogen: Ten compounds which are positive in the mouse lymphoma assay but are not genotoxic carcinogens
    • Caldwell, J. (1993) Perspective on the usefulness of the mouse lymphoma assay as an indicator of a genotoxic carcinogen: ten compounds which are positive in the mouse lymphoma assay but are not genotoxic carcinogens. Teratogen. Carcinogen. Mutagen., 13, 185-190.
    • (1993) Teratogen. Carcinogen. Mutagen. , vol.13 , pp. 185-190
    • Caldwell, J.1
  • 14
    • 0023883618 scopus 로고
    • The mutagenic activity of selected compounds at the TK locus: Rodent vs. human cells
    • Caspary, W., Langenbach, R., Penman, B.W., Crespi, C., Myhr, B.C. and Mitchell, A.D. (1988) The mutagenic activity of selected compounds at the TK locus: rodent vs. human cells. Mutat. Res., 196, 61-81.
    • (1988) Mutat. Res. , vol.196 , pp. 61-81
    • Caspary, W.1    Langenbach, R.2    Penman, B.W.3    Crespi, C.4    Myhr, B.C.5    Mitchell, A.D.6
  • 17
    • 0025158299 scopus 로고
    • Microwell mutation assays: Evaluation of ethylmethanesulfonate, benzo[a]pyrene and benzidine using the tk locus in L5178Y mouse lymphoma cells
    • Clay, P. and Cross, M.F. (1990) Microwell mutation assays: evaluation of ethylmethanesulfonate, benzo[a]pyrene and benzidine using the tk locus in L5178Y mouse lymphoma cells. Mutagenesis, 5 (suppl.), 45-54.
    • (1990) Mutagenesis , vol.5 , Issue.SUPPL. , pp. 45-54
    • Clay, P.1    Cross, M.F.2
  • 18
    • 0016423549 scopus 로고
    • Laboratory procedure for assessing specific locus mutations at the Tk locus in cultured L5178Y mouse lymphoma cells
    • Clive, D. and Spector, J.F.S. (1975) Laboratory procedure for assessing specific locus mutations at the Tk locus in cultured L5178Y mouse lymphoma cells. Mutat. Res., 31, 17-29.
    • (1975) Mutat. Res. , vol.31 , pp. 17-29
    • Clive, D.1    Spector, J.F.S.2
  • 19
    • 0018327785 scopus 로고
    • Validation and characterization of the L5178Y/TK+/- mouse lymphoma mutagen assay system
    • Clive, D., Johnson, K.O., Spector, J.F.S., Batson, A.G. and Brown, M.M.M. (1979) Validation and characterization of the L5178Y/TK+/- mouse lymphoma mutagen assay system. Mutat. Res., 59, 61-108.
    • (1979) Mutat. Res. , vol.59 , pp. 61-108
    • Clive, D.1    Johnson, K.O.2    Spector, J.F.S.3    Batson, A.G.4    Brown, M.M.M.5
  • 20
    • 0010393211 scopus 로고
    • The mouse lymphoma assay may also be used as a chromosome aberration assay
    • Clive, D., Turner, N.T., Krehl, R. and Eyre, J. (1985) The mouse lymphoma assay may also be used as a chromosome aberration assay. Environ. Mutagen., 7, 33.
    • (1985) Environ. Mutagen. , vol.7 , pp. 33
    • Clive, D.1    Turner, N.T.2    Krehl, R.3    Eyre, J.4
  • 21
    • 0025147998 scopus 로고
    • Molecular aspects of chemical mutagenesis in L5178Y/tk+/- mouse lymphoma cells
    • Clive, D., Glover, P., Applegate, M. and Hozier, J. (1990) Molecular aspects of chemical mutagenesis in L5178Y/tk+/- mouse lymphoma cells. Mutagenesis, 5, 191-197.
    • (1990) Mutagenesis , vol.5 , pp. 191-197
    • Clive, D.1    Glover, P.2    Applegate, M.3    Hozier, J.4
  • 23
    • 0021015467 scopus 로고
    • A comparison of the agar cloning and microtitration techniques for assaying cell survival and mutation frequency in L5178Y mouse lymphoma cells
    • Cole, J., Arlett, C.F. Green, M.H.L., Lowe, J. and Muriel, W. (1983) A comparison of the agar cloning and microtitration techniques for assaying cell survival and mutation frequency in L5178Y mouse lymphoma cells. Mutat. Res., 111, 371-386.
    • (1983) Mutat. Res. , vol.111 , pp. 371-386
    • Cole, J.1    Arlett, C.F.2    Green, M.H.L.3    Lowe, J.4    Muriel, W.5
  • 25
    • 0025737472 scopus 로고
    • The mutagenicity of 2-amino-N6-hydroxyadenine to L5178Y tk+/- mouse lymphoma cells: Measurement of mutations to ouabain, 6-thioguanine and trifluorothymidine resistance, and the induction of micronuclei
    • Cole, J., Richmond, F.N. and Bridges, B.A. (1991) The mutagenicity of 2-amino-N6-hydroxyadenine to L5178Y tk+/- mouse lymphoma cells: measurement of mutations to ouabain, 6-thioguanine and trifluorothymidine resistance, and the induction of micronuclei. Mutat. Res., 253, 55-62.
    • (1991) Mutat. Res. , vol.253 , pp. 55-62
    • Cole, J.1    Richmond, F.N.2    Bridges, B.A.3
  • 26
    • 0029095542 scopus 로고
    • The use of L5178Y mouse lymphoma cells to asses the mutagenic, clastogenic and aneugenic properties of chemicals
    • Combes, R.D., Stopper, H. and Caspary, W.J. (1995) The use of L5178Y mouse lymphoma cells to asses the mutagenic, clastogenic and aneugenic properties of chemicals. Mutagenesis, 10, 403-408.
    • (1995) Mutagenesis , vol.10 , pp. 403-408
    • Combes, R.D.1    Stopper, H.2    Caspary, W.J.3
  • 27
    • 0344399598 scopus 로고
    • Potential EPA/OPP mutagenicity testing requirements - Guidelines revisions
    • Dearfield, K.L. (1989) Potential EPA/OPP mutagenicity testing requirements - guidelines revisions. Environ. Mol. Mutagen., 14, 47.
    • (1989) Environ. Mol. Mutagen. , vol.14 , pp. 47
    • Dearfield, K.L.1
  • 28
    • 0343072811 scopus 로고
    • Considerations in the U.S. Environmental protection agency's testing approach for mutagenicity
    • Dearfield, K.L., Auletta, A.E., Cimino, M.C. and Moore, M.M. (1991) Considerations in the U.S. Environmental Protection Agency's testing approach for mutagenicity. Mutat. Res., 258, 259-283.
    • (1991) Mutat. Res. , vol.258 , pp. 259-283
    • Dearfield, K.L.1    Auletta, A.E.2    Cimino, M.C.3    Moore, M.M.4
  • 29
    • 0004099303 scopus 로고
    • DHSS Report on Health and Social Subjects no. 35. HMSO, London, UK
    • DHSS UK (1989) Guidelines for Testing Chemicals for Mutagenicity. DHSS Report on Health and Social Subjects no. 35. HMSO, London, UK.
    • (1989) Guidelines for Testing Chemicals for Mutagenicity
  • 30
    • 0022255934 scopus 로고
    • Toxicity and mutagenicity tests of 4 anti-cancer drugs in cultured Chinese hamster cells
    • Dickins, M., Wright, K., Phillips, M. and Todd, N. (1985) Toxicity and mutagenicity tests of 4 anti-cancer drugs in cultured Chinese hamster cells. Mutat. Res., 143, 149-154.
    • (1985) Mutat. Res. , vol.143 , pp. 149-154
    • Dickins, M.1    Wright, K.2    Phillips, M.3    Todd, N.4
  • 31
    • 0022330775 scopus 로고
    • Reproducibility of microbial mutagenicity assays: II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Esherrichia coli
    • Dunkel, V.C., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K. and Simmon, V.F. (1985) Reproducibility of microbial mutagenicity assays: II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Esherrichia coli. Environ. Mutagen., 7 (suppl. 5), 1-248.
    • (1985) Environ. Mutagen. , vol.7 , Issue.SUPPL. 5 , pp. 1-248
    • Dunkel, V.C.1    Zeiger, E.2    Brusick, D.3    McCoy, E.4    McGregor, D.5    Mortelmans, K.6    Simmon, V.F.7
  • 33
    • 0019404906 scopus 로고
    • Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates
    • Furth, E.M., Thilly, W.G., Penman, B.A., Liber, H.L. and Rand, W.M. (1981) Quantitative assay for mutation in diploid human lymphoblasts using microtiter plates. Anal. Biochem., 110, 1-8.
    • (1981) Anal. Biochem. , vol.110 , pp. 1-8
    • Furth, E.M.1    Thilly, W.G.2    Penman, B.A.3    Liber, H.L.4    Rand, W.M.5
  • 35
    • 0023932157 scopus 로고
    • Evaluation of a genotoxicity test measuring DNA-strand breaks in mouse lymphoma cells by unwinding and hydroxyapatite elution
    • Garberg, P., Akerblom, E.-L. and Bolcsfoldi, G. (1988) Evaluation of a genotoxicity test measuring DNA-strand breaks in mouse lymphoma cells by unwinding and hydroxyapatite elution. Mutat. Res., 203, 155-176.
    • (1988) Mutat. Res. , vol.203 , pp. 155-176
    • Garberg, P.1    Akerblom, E.-L.2    Bolcsfoldi, G.3
  • 36
    • 0028986995 scopus 로고
    • International workshop on mouse lymphoma assay testing practices and data interpretations: Portland, Oregon, May 7, 1994
    • Garriot, M.L., Casciano, D.A., Schechtman, L.M. and Probst, G.S. (1995) International workshop on mouse lymphoma assay testing practices and data interpretations: Portland, Oregon, May 7, 1994. Environ. Mol. Mutagen., 25, 162-164.
    • (1995) Environ. Mol. Mutagen. , vol.25 , pp. 162-164
    • Garriot, M.L.1    Casciano, D.A.2    Schechtman, L.M.3    Probst, G.S.4
  • 37
    • 0025741556 scopus 로고
    • Investigation into the induction of aneuploidy and polyploidy in mammalian cells by the anti-tussive agent noscapine hydrochloride
    • Gatehouse, D.G., Stemp, G., Pascoe, S., Wilcox, P., Hawker, J. and Tweats, D.J. (1991) Investigation into the induction of aneuploidy and polyploidy in mammalian cells by the anti-tussive agent noscapine hydrochloride. Mutagenesis, 6, 279-283.
    • (1991) Mutagenesis , vol.6 , pp. 279-283
    • Gatehouse, D.G.1    Stemp, G.2    Pascoe, S.3    Wilcox, P.4    Hawker, J.5    Tweats, D.J.6
  • 38
    • 0018706185 scopus 로고
    • Mutagenicity of quinoline derivatives and analogs - Quinoxaline 1,4-dioxide is a potent mutagen
    • Hashimoto, T., Negishi, T., Namba, T., Hayakawa, S. and Hayatsu, H. (1979) Mutagenicity of quinoline derivatives and analogs - quinoxaline 1,4-dioxide is a potent mutagen. Chem. Pharm. Bull., 27, 219-224.
    • (1979) Chem. Pharm. Bull. , vol.27 , pp. 219-224
    • Hashimoto, T.1    Negishi, T.2    Namba, T.3    Hayakawa, S.4    Hayatsu, H.5
  • 39
  • 40
    • 0013488933 scopus 로고
    • On the use of multiple assays for mutagenicity, especially the micronucleus. Salmonella, and sperm abnormality assays
    • Scott, D., Bridges, B.A. and Sobels, F.H. (eds). Elsevier/North-Holland, Amsterdam, The Netherlands
    • Heddle, J.A. and Bruce, W.R. (1977) On the use of multiple assays for mutagenicity, especially the micronucleus. Salmonella, and sperm abnormality assays. In Scott, D., Bridges, B.A. and Sobels, F.H. (eds). Progress in Genetic Toxicology. Elsevier/North-Holland, Amsterdam, The Netherlands, pp. 265-274.
    • (1977) Progress in Genetic Toxicology , pp. 265-274
    • Heddle, J.A.1    Bruce, W.R.2
  • 41
    • 0030957103 scopus 로고    scopus 로고
    • Chlorambucil-induced structural changes in the gpt gene of AS52 cells
    • Honma, M., Hayashi, M., Hackman, P. and Sofuni, T. (1997) Chlorambucil-induced structural changes in the gpt gene of AS52 cells. Mutat. Res., 389, 199-205.
    • (1997) Mutat. Res. , vol.389 , pp. 199-205
    • Honma, M.1    Hayashi, M.2    Hackman, P.3    Sofuni, T.4
  • 47
    • 0023917946 scopus 로고
    • A proposed battery of tests for the initial evaluation of the mutagenic potential of medicinal and industrial chemicals
    • Ishidate, M., Jr (1988) A proposed battery of tests for the initial evaluation of the mutagenic potential of medicinal and industrial chemicals. Mutat. Res., 205, 397-407.
    • (1988) Mutat. Res. , vol.205 , pp. 397-407
    • Ishidate M., Jr.1
  • 49
    • 0024435027 scopus 로고
    • Chromosomal aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. IV. Results with 15 chemicals
    • Ivett, J.L., Brown, B.M., Rodgers, C., Anderson, B.E., Resnick, M.A. and Zeiger, E. (1989) Chromosomal aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro. IV. Results with 15 chemicals. Environ. Mol. Mutagen., 14, 165-187.
    • (1989) Environ. Mol. Mutagen. , vol.14 , pp. 165-187
    • Ivett, J.L.1    Brown, B.M.2    Rodgers, C.3    Anderson, B.E.4    Resnick, M.A.5    Zeiger, E.6
  • 50
    • 0022400809 scopus 로고
    • The Reproductive Effects Assessment Group's report on the mutagenicity of inorganic arsenic
    • Jacobson-Kram, D. and Montalbano, D. (1985) The Reproductive Effects Assessment Group's report on the mutagenicity of inorganic arsenic. Environ. Mutagen., 7, 787-804.
    • (1985) Environ. Mutagen. , vol.7 , pp. 787-804
    • Jacobson-Kram, D.1    Montalbano, D.2
  • 51
    • 0000014016 scopus 로고
    • Effect of 20 coded chemicals on the forward mutation frequency at the thymidine kinase locus in L5178Y mouse lymphoma cells
    • Jotz, M.M. and Mitchell, A.D. (1981) Effect of 20 coded chemicals on the forward mutation frequency at the thymidine kinase locus in L5178Y mouse lymphoma cells. Prog. Mutat. Res., 1, 580-593.
    • (1981) Prog. Mutat. Res. , vol.1 , pp. 580-593
    • Jotz, M.M.1    Mitchell, A.D.2
  • 52
    • 0016224708 scopus 로고
    • Griseofulvin: A potent agent of chromosomal segregation in cultured cells
    • Larizza, L., Simoni, G., Tredici, F. and DeCarli, L. (1974) Griseofulvin: a potent agent of chromosomal segregation in cultured cells. Mutat. Res., 25, 123-130.
    • (1974) Mutat. Res. , vol.25 , pp. 123-130
    • Larizza, L.1    Simoni, G.2    Tredici, F.3    DeCarli, L.4
  • 53
    • 0027977153 scopus 로고
    • Evaluation of the genotoxic potential of alkyleneamines
    • Leung, H.-W. (1994) Evaluation of the genotoxic potential of alkyleneamines. Mutat. Res., 320, 31-43.
    • (1994) Mutat. Res. , vol.320 , pp. 31-43
    • Leung, H.-W.1
  • 55
    • 0025649627 scopus 로고
    • Development of an optimal S9 activation mixture for the L5178YTK+/- mouse lymphoma mutation assay
    • Majeska, J.B. and Matheson, D.W. (1990) Development of an optimal S9 activation mixture for the L5178YTK+/- mouse lymphoma mutation assay. Environ. Mol. Mutagen., 16, 311-319.
    • (1990) Environ. Mol. Mutagen. , vol.16 , pp. 311-319
    • Majeska, J.B.1    Matheson, D.W.2
  • 56
    • 0022005305 scopus 로고
    • Study of the mutagenicity of metal derivatives with Salmonella typhimurium TA102
    • Marzin, D.R. and Phi, H.V. (1985) Study of the mutagenicity of metal derivatives with Salmonella typhimurium TA102. Mutat. Res., 155, 49-51.
    • (1985) Mutat. Res. , vol.155 , pp. 49-51
    • Marzin, D.R.1    Phi, H.V.2
  • 58
    • 0001406666 scopus 로고
    • Detection of carcinogens as mutagens in the Salmonella/microsome test, assay of 300 chemicals
    • McCann, J., Choi, E., Yamasaki, E. and Ames, B. (1975) Detection of carcinogens as mutagens in the Salmonella/microsome test, assay of 300 chemicals. Proc. Natl Acad. Sci. USA, 72, 5135-5139.
    • (1975) Proc. Natl Acad. Sci. USA , vol.72 , pp. 5135-5139
    • McCann, J.1    Choi, E.2    Yamasaki, E.3    Ames, B.4
  • 59
    • 0023873563 scopus 로고
    • Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. II: 18 coded chemicals
    • McGregor, D.B., Brown, A., Cattanach, P., Edwards, I., McBride, D. and Caspary, W.J. (1988a) Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. II: 18 coded chemicals. Environ. Mol. Mutagen., 11, 91-118.
    • (1988) Environ. Mol. Mutagen. , vol.11 , pp. 91-118
    • McGregor, D.B.1    Brown, A.2    Cattanach, P.3    Edwards, I.4    McBride, D.5    Caspary, W.J.6
  • 61
    • 0025905441 scopus 로고
    • Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. V: 27 coded chemicals
    • McGregor, D.B., Brown, A.C., Howgate, S., McBride, D., Riach, C. and Caspary, W.J. (1991) Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay. V: 27 coded chemicals. Environ. Mol. Mutagen., 17, 196-219.
    • (1991) Environ. Mol. Mutagen. , vol.17 , pp. 196-219
    • McGregor, D.B.1    Brown, A.C.2    Howgate, S.3    McBride, D.4    Riach, C.5    Caspary, W.J.6
  • 64
    • 0031474758 scopus 로고    scopus 로고
    • +/- mouse lymphoma specific gene and chromosomal mutation assay. A phase III report of the U.S. Environmental Protection Agency Gene-Tox Program
    • +/- mouse lymphoma specific gene and chromosomal mutation assay. A phase III report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat. Res., 394, 177-303.
    • (1997) Mutat. Res. , vol.394 , pp. 177-303
    • Mitchell, A.D.1    Auletta, A.E.2    Clive, D.3    Kirby, P.E.4    Moore, M.M.5    Myhr, B.C.6
  • 65
    • 0021356641 scopus 로고
    • Chromosomal effects of methotrexate on cultured human lymphocytes
    • Mondello, C., Giorgi, R. and Nuzzo, F. (1984) Chromosomal effects of methotrexate on cultured human lymphocytes. Mutat. Res., 139, 67-70.
    • (1984) Mutat. Res. , vol.139 , pp. 67-70
    • Mondello, C.1    Giorgi, R.2    Nuzzo, F.3
  • 66
    • 0019413371 scopus 로고
    • The utilization of trifluorothymidine (TFT) to select for thymidine kinase-deficient (TK-/-) mutants from L5178Y/TK+/- mouse lymphoma cells
    • Moore-Brown, M.M., Clive, D., Howard, B.E., Batson, A.G. and Johnson, K.O. (1981) The utilization of trifluorothymidine (TFT) to select for thymidine kinase-deficient (TK-/-) mutants from L5178Y/TK+/- mouse lymphoma cells. Mutat. Res., 85, 363-378.
    • (1981) Mutat. Res. , vol.85 , pp. 363-378
    • Moore-Brown, M.M.1    Clive, D.2    Howard, B.E.3    Batson, A.G.4    Johnson, K.O.5
  • 67
    • 0019954426 scopus 로고
    • The quantitation of TK-/-and HGPRT-mutants of L5178Y/TK+/-mouse lymphoma cells at varying times posttreatment
    • Moore, M.M. and Clive, D. (1982) The quantitation of TK-/-and HGPRT-mutants of L5178Y/TK+/-mouse lymphoma cells at varying times posttreatment. Environ. Mutagen., 4, 499-519.
    • (1982) Environ. Mutagen. , vol.4 , pp. 499-519
    • Moore, M.M.1    Clive, D.2
  • 68
    • 0019945050 scopus 로고
    • Quantitation of small colony trifluorothymidine-resistant mutants of L5178Y/TK+/-mouse lymphoma cells in RPMI-1640 medium
    • Moore, M.M. and Howard, B.E. (1982) Quantitation of small colony trifluorothymidine-resistant mutants of L5178Y/TK+/-mouse lymphoma cells in RPMI-1640 medium. Mutat. Res., 104, 287-294.
    • (1982) Mutat. Res. , vol.104 , pp. 287-294
    • Moore, M.M.1    Howard, B.E.2
  • 69
    • 0022262801 scopus 로고
    • Analysis of trifluorothymidine-resistant (TFT) mutants of L5178Y/TK+/-mouse lymphoma cells
    • Moore, M.M., Clive, D., Hozier, J.C., Howard, B.E., Batson, A.G., Turner, N.T. and Sawyer, J. (1985) Analysis of trifluorothymidine-resistant (TFT) mutants of L5178Y/TK+/-mouse lymphoma cells. Mutat. Res., 151, 161-174.
    • (1985) Mutat. Res. , vol.151 , pp. 161-174
    • Moore, M.M.1    Clive, D.2    Hozier, J.C.3    Howard, B.E.4    Batson, A.G.5    Turner, N.T.6    Sawyer, J.7
  • 71
    • 0023746946 scopus 로고
    • Evaluation of L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three chemicals tested at Litton Bionetics, Inc.
    • Myhr, B.C. and Caspary, W.J. (1988) Evaluation of L5178Y mouse lymphoma cell mutagenesis assay: intralaboratory results for sixty-three chemicals tested at Litton Bionetics, Inc. Environ. Mol. Mutagen., 12, 103-194.
    • (1988) Environ. Mol. Mutagen. , vol.12 , pp. 103-194
    • Myhr, B.C.1    Caspary, W.J.2
  • 72
    • 0025744675 scopus 로고
    • Chemical mutagenesis at the thymidine kinase locus in L5178Y mouse lymphoma cells: Results for 31 coded compounds in the National Toxicology Program
    • Myhr, B.C. and Caspary, W.J. (1991) Chemical mutagenesis at the thymidine kinase locus in L5178Y mouse lymphoma cells: results for 31 coded compounds in the National Toxicology Program. Environ. Mol. Mutagen., 18, 51-83.
    • (1991) Environ. Mol. Mutagen. , vol.18 , pp. 51-83
    • Myhr, B.C.1    Caspary, W.J.2
  • 74
    • 0019220128 scopus 로고
    • Comparative studies of chromosomal aberration induced by trivalent and pentavalent arsenic
    • Nakamuro, K. and Sayoto, Y. (1981) Comparative studies of chromosomal aberration induced by trivalent and pentavalent arsenic. Mutat. Res., 88, 73-80.
    • (1981) Mutat. Res. , vol.88 , pp. 73-80
    • Nakamuro, K.1    Sayoto, Y.2
  • 75
    • 0019953305 scopus 로고
    • Mutagenicity of metal salts in the L5178Y mouse lymphoma assay
    • Oberly, T.J., Piper, C.E. and McDonald, D.S. (1982) Mutagenicity of metal salts in the L5178Y mouse lymphoma assay. J. Toxicol. Environ, Health, 9, 367-376.
    • (1982) J. Toxicol. Environ, Health , vol.9 , pp. 367-376
    • Oberly, T.J.1    Piper, C.E.2    McDonald, D.S.3
  • 76
    • 0021329775 scopus 로고
    • An evaluation of the L5178Y TK+/- mouse lymphoma forward mutation assay using 42 chemicals
    • Oberly, T.J., Bewsey, B.J. and Probst G.S. (1984) An evaluation of the L5178Y TK+/- mouse lymphoma forward mutation assay using 42 chemicals. Mutat. Res., 125, 291-306.
    • (1984) Mutat. Res. , vol.125 , pp. 291-306
    • Oberly, T.J.1    Bewsey, B.J.2    Probst, G.S.3
  • 77
    • 0027430866 scopus 로고
    • A comparison of the CHO/HGPRT+ and L5178Y/TK+/- mutation assays using suspension treatment and soft agar cloning: Results for 10 chemicals
    • Oberly, T.J., Michealis, K.C., Rexroat, M.A., Bewsey, B.J. and Garriott, M.L. (1993) A comparison of the CHO/HGPRT+ and L5178Y/TK+/- mutation assays using suspension treatment and soft agar cloning: results for 10 chemicals. Cell Biol. Toxicol., 9, 243-257.
    • (1993) Cell Biol. Toxicol. , vol.9 , pp. 243-257
    • Oberly, T.J.1    Michealis, K.C.2    Rexroat, M.A.3    Bewsey, B.J.4    Garriott, M.L.5
  • 79
    • 0345262444 scopus 로고
    • Mutagenicity studies of YK-176
    • Otsuka, M. et al. (1991) Mutagenicity studies of YK-176. Kiso To Rinsyo, 25, 1311-1320.
    • (1991) Kiso To Rinsyo , vol.25 , pp. 1311-1320
    • Otsuka, M.1
  • 81
    • 0000995727 scopus 로고
    • Statistical evaluation of bacterial/mammalian fluctuation tests
    • Kirkland, D.J. (ed.). Cambridge University Press, Cambridge. UK.
    • Robinson, W.D., Green, M.H.L., Cole, J., Healy, M.J.R., Garner, R.C. and Gatehouse, D. (1989) Statistical evaluation of bacterial/mammalian fluctuation tests. In Kirkland, D.J. (ed.). Statistical Evaluation of Mutugenicity. Cambridge University Press, Cambridge. UK. pp. 102-140.
    • (1989) Statistical Evaluation of Mutugenicity , pp. 102-140
    • Robinson, W.D.1    Green, M.H.L.2    Cole, J.3    Healy, M.J.R.4    Garner, R.C.5    Gatehouse, D.6
  • 82
    • 0018325466 scopus 로고
    • Chromosomal aberration of don lung cells of Chinese hamster after exposure to vinblastine in vitro
    • Segawa, M., Nadamitsu, S., Kondo, K. and Yoshizaki, I. (1979) Chromosomal aberration of Don lung cells of Chinese hamster after exposure to vinblastine in vitro. Mutat. Res., 66, 99-102.
    • (1979) Mutat. Res. , vol.66 , pp. 99-102
    • Segawa, M.1    Nadamitsu, S.2    Kondo, K.3    Yoshizaki, I.4
  • 83
    • 0018098983 scopus 로고
    • Mutagenicity of several classes of antitumor agents to Salmonella typhimurium TA98. TA100, and TA92
    • Seino, Y., Nagao, M., Yahagi, T., Hoshi, A., Kawachi, T. and Sugimura, T. (1978) Mutagenicity of several classes of antitumor agents to Salmonella typhimurium TA98. TA100, and TA92. Cancer Res., 38, 2148-2156.
    • (1978) Cancer Res. , vol.38 , pp. 2148-2156
    • Seino, Y.1    Nagao, M.2    Yahagi, T.3    Hoshi, A.4    Kawachi, T.5    Sugimura, T.6
  • 84
    • 0020028632 scopus 로고
    • Genotoxicity of safrol-related chemicals in microbial test systems
    • Sekizawa, J. and Shibamoto, T. (1982) Genotoxicity of safrol-related chemicals in microbial test systems. Mutat. Res., 101, 127-140.
    • (1982) Mutat. Res. , vol.101 , pp. 127-140
    • Sekizawa, J.1    Shibamoto, T.2
  • 85
    • 0023875237 scopus 로고
    • Effect of cycloheximide on development of methotrexate resistance of Chinese hamster ovary cells treated with inhibitors of DNA synthesis
    • Sherwood, S.W., Schumacher, R.T. and Schmke, R.T. (1988) Effect of cycloheximide on development of methotrexate resistance of Chinese hamster ovary cells treated with inhibitors of DNA synthesis. Mol. Cell. Biol., 8, 2822-2827.
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 2822-2827
    • Sherwood, S.W.1    Schumacher, R.T.2    Schmke, R.T.3
  • 86
    • 0020657298 scopus 로고
    • Structural specificity of aromatic compounds with special reference to mutagenic activity in Salmonella typhimurium - A series of chloro- or fluoro-nitrobenzene derivatives
    • Shimizu, M., Yasui, Y. and Matsumoto, N. (1983) Structural specificity of aromatic compounds with special reference to mutagenic activity in Salmonella typhimurium - a series of chloro- or fluoro-nitrobenzene derivatives. Mutat. Res., 116, 217-238.
    • (1983) Mutat. Res. , vol.116 , pp. 217-238
    • Shimizu, M.1    Yasui, Y.2    Matsumoto, N.3
  • 87
    • 0022966182 scopus 로고
    • Results of genotoxicity testing of theophylline on bacteria and two lines of mammalian cells
    • Slamenova, D., Budayova, E., Dusinska, M. and Gabelova, G. (1986a) Results of genotoxicity testing of theophylline on bacteria and two lines of mammalian cells. Neoplasma, 33, 457-463.
    • (1986) Neoplasma , vol.33 , pp. 457-463
    • Slamenova, D.1    Budayova, E.2    Dusinska, M.3    Gabelova, G.4
  • 88
    • 0022902842 scopus 로고
    • Prescreening of carcinogens by studying of DNA synthesis inhibition and gene mutations in mammalian cells
    • Slamenova, D., Budayova, E., Gabelova, A. and Dusinska, M. (1986b) Prescreening of carcinogens by studying of DNA synthesis inhibition and gene mutations in mammalian cells. Neoplasma, 33, 699-706.
    • (1986) Neoplasma , vol.33 , pp. 699-706
    • Slamenova, D.1    Budayova, E.2    Gabelova, A.3    Dusinska, M.4
  • 89
    • 8944224535 scopus 로고    scopus 로고
    • Detection of in vitro clastogens and spindle poisons by the mouse lymphoma assay using the microwell method: Interim report of an international collaborative study
    • Sofuni, T., Honma, M., Hayashi, M., Shimada, H., Tanaka, N., Wakuri, S., Awogi, T., Yamamoto, K.I., Nishi, Y. and Nakadale, M. (1996) Detection of in vitro clastogens and spindle poisons by the mouse lymphoma assay using the microwell method: interim report of an international collaborative study. Mutagenesis, 11, 349-355.
    • (1996) Mutagenesis , vol.11 , pp. 349-355
    • Sofuni, T.1    Honma, M.2    Hayashi, M.3    Shimada, H.4    Tanaka, N.5    Wakuri, S.6    Awogi, T.7    Yamamoto, K.I.8    Nishi, Y.9    Nakadale, M.10
  • 91
    • 0030742767 scopus 로고    scopus 로고
    • Mouse Lymphoma Workshop: Victoria, British Columbia, Canada, March 27, 1996: Protocol issues regarding the use of the microwell method of the mouse lymphoma assay
    • Sofuni, T., Wilcox, P., Shimada, H., Clements, J., Honma, M., Clive, D., Green, M., Thyband, V., San, R.H.C, Elliott, B.M. and Müller, L. (1997b) Mouse Lymphoma Workshop: Victoria, British Columbia, Canada, March 27, 1996: protocol issues regarding the use of the microwell method of the mouse lymphoma assay. Environ. Mol. Mutagen., 29, 434-438.
    • (1997) Environ. Mol. Mutagen. , vol.29 , pp. 434-438
    • Sofuni, T.1    Wilcox, P.2    Shimada, H.3    Clements, J.4    Honma, M.5    Clive, D.6    Green, M.7    Thyband, V.8    San, R.H.C.9    Elliott, B.M.10    Müller, L.11
  • 92
    • 0018954840 scopus 로고
    • Relative mutagenicity of antineoplastic drugs and other alkylating agents in V79 Chinese hamster cells, independence of cytotoxic and mutagenic responses
    • Suter, W., Brennand, J., McMillan, S. and Fox, M. (1980) Relative mutagenicity of antineoplastic drugs and other alkylating agents in V79 Chinese hamster cells, independence of cytotoxic and mutagenic responses. Mutat. Res., 73, 171-181.
    • (1980) Mutat. Res. , vol.73 , pp. 171-181
    • Suter, W.1    Brennand, J.2    McMillan, S.3    Fox, M.4
  • 93
    • 0026736171 scopus 로고
    • Resistance to Pseudomonas toxin A: A sensitive marker to screen for mutagenic substances using V79 cells
    • Suter, W., Negro, L., Barrera, I., and Schneider, B. (1992) Resistance to Pseudomonas toxin A: a sensitive marker to screen for mutagenic substances using V79 cells. Mutagenesis, 7, 125-135.
    • (1992) Mutagenesis , vol.7 , pp. 125-135
    • Suter, W.1    Negro, L.2    Barrera, I.3    Schneider, B.4
  • 95
    • 0011871108 scopus 로고
    • Deletion mutations are associated with the differential induced mutant frequency response of the AS52 and CHO-KI-BH4 cell lines
    • Moore, M.M., DeMarini, D.M., DeSerres, F.J. and Tindall, K.R. (eds). Cold Spring Harbor Laboratory Press. Cold Spring Harbor, NY
    • Tindall, K.R. and Stankowski, L.F. (1987) Deletion mutations are associated with the differential induced mutant frequency response of the AS52 and CHO-KI-BH4 cell lines. In Moore, M.M., DeMarini, D.M., DeSerres, F.J. and Tindall, K.R. (eds). Mammalian Cell Mutagenesis, Banbury Report 28. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, NY, pp. 283-299.
    • (1987) Mammalian Cell Mutagenesis, Banbury Report 28 , vol.28 , pp. 283-299
    • Tindall, K.R.1    Stankowski, L.F.2
  • 96
    • 0001474019 scopus 로고
    • Procedure for the L5178Y/ TK+/-to TK-/-mouse lymphoma cell mutagenicity assay
    • Kilbey, B.J., Legator, M., Nichols, W. and Ramel, C. (eds), Elsevier, Amsterdam, The Netherlands
    • Turner, N.T. Batson, A.J. and Clive, D. (1984) Procedure for the L5178Y/ TK+/-to TK-/-mouse lymphoma cell mutagenicity assay. In Kilbey, B.J., Legator, M., Nichols, W. and Ramel, C. (eds), Handbook of Mutagenicity Test Procedures. Elsevier, Amsterdam, The Netherlands, pp. 239-268.
    • (1984) Handbook of Mutagenicity Test Procedures , pp. 239-268
    • Turner, N.T.1    Batson, A.J.2    Clive, D.3
  • 97
    • 0015158112 scopus 로고
    • The effect of monocrotaline, a pyrrolizidine alkaloid, on HeLa cells and primary cultured cells from rat liver and lung
    • Umeda, M. and Saito, M. (1971) The effect of monocrotaline, a pyrrolizidine alkaloid, on HeLa cells and primary cultured cells from rat liver and lung. Acta. Pathol. Jpn. 21, 507-514.
    • (1971) Acta. Pathol. Jpn. , vol.21 , pp. 507-514
    • Umeda, M.1    Saito, M.2
  • 98
    • 0018170790 scopus 로고
    • A study of the mutagenicity of anesthetics and their metabolites
    • Waskell, L. (1978) A study of the mutagenicity of anesthetics and their metabolites. Mutat. Res., 57, 141-153.
    • (1978) Mutat. Res. , vol.57 , pp. 141-153
    • Waskell, L.1
  • 99
    • 0017880759 scopus 로고
    • Lack of mutagenicity to Salmonella typhimurium of some fusarium mycoloxins
    • Wehner, F.C., Marasas, W.F.O. and Thiel.P.G. (1978a) Lack of mutagenicity to Salmonella typhimurium of some fusarium mycoloxins. Appl. Environ. Microbiol., 35, 659-662.
    • (1978) Appl. Environ. Microbiol. , vol.35 , pp. 659-662
    • Wehner, F.C.1    Marasas, W.F.O.2
  • 100
    • 0018071942 scopus 로고
    • Mutagenicity to Salmonella typhimurium of some aspergillus and penicillium mycotoxins
    • Wehner, F.C., Thiel, P.G., VanRensburg, S.J. and Demasius, I.P.C. (1978b) Mutagenicity to Salmonella typhimurium of some aspergillus and penicillium mycotoxins. Mutat. Res., 58, 193-203.
    • (1978) Mutat. Res. , vol.58 , pp. 193-203
    • Wehner, F.C.1    Thiel, P.G.2    VanRensburg, S.J.3    Demasius, I.P.C.4
  • 101
    • 0019864293 scopus 로고
    • Use of rat/hamster S-9 mixture in the Ames mutagenicity assay
    • Weinstein, D., Katz, M. and Kazmer, S. (1981) Use of rat/hamster S-9 mixture in the Ames mutagenicity assay. Environ. Mutagen., 3, 1-9.
    • (1981) Environ. Mutagen. , vol.3 , pp. 1-9
    • Weinstein, D.1    Katz, M.2    Kazmer, S.3
  • 102
    • 0019352749 scopus 로고
    • Reverse mutation tests in Salmonella typhimurium and chromosomal aberration tests in mammalian cells in culture on fluorinated pyrimidine derivatives
    • Yajima, N., Kondo, K. and Morita, K. (1981) Reverse mutation tests in Salmonella typhimurium and chromosomal aberration tests in mammalian cells in culture on fluorinated pyrimidine derivatives. Mutat. Res., 88, 241-254.
    • (1981) Mutat. Res. , vol.88 , pp. 241-254
    • Yajima, N.1    Kondo, K.2    Morita, K.3
  • 103
    • 0344831107 scopus 로고
    • Mutagenicity of pyrrolizidine alkaloids in the Salmonellal mammalian-microsome test
    • Yamanaka, H., Nagao, M., Sugimura, T., Furuya, T., Shirai, A. and Matsushima.T. (1979) Mutagenicity of pyrrolizidine alkaloids in the Salmonellal mammalian-microsome test. Mutat. Res., 285, 27-33.
    • (1979) Mutat. Res. , vol.285 , pp. 27-33
    • Yamanaka, H.1    Nagao, M.2    Sugimura, T.3    Furuya, T.4    Shirai, A.5    Matsushima, T.6
  • 106
    • 0025184162 scopus 로고
    • Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: Confirmation of earlier results with 41 additional chemicals
    • Zeiger, E., Haseman, J.K., Shelby, M.D., Margolin, B.H. and Tennant, R.W. (1990) Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: confirmation of earlier results with 41 additional chemicals. Environ. Mol. Mutagen., 16, 1-14.
    • (1990) Environ. Mol. Mutagen. , vol.16 , pp. 1-14
    • Zeiger, E.1    Haseman, J.K.2    Shelby, M.D.3    Margolin, B.H.4    Tennant, R.W.5
  • 107
    • 0030272968 scopus 로고    scopus 로고
    • Chromosome painting analysis of spontaneous and methylmethanesulfonate-induced trifluorothymidine-resistant L5178Y cell colonies
    • Zhang, L.-S., Honma, M., Matsuoka, A., Suzuki, T., Sofuni, T. and Hayashi, M. (1996) Chromosome painting analysis of spontaneous and methylmethanesulfonate-induced trifluorothymidine-resistant L5178Y cell colonies. Mutat. Res., 370, 181-190.
    • (1996) Mutat. Res. , vol.370 , pp. 181-190
    • Zhang, L.-S.1    Honma, M.2    Matsuoka, A.3    Suzuki, T.4    Sofuni, T.5    Hayashi, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.