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Proceedings of the National Academy of Sciences of the United States of America

Volumn 99, Issue 13, 2002, Pages 8579-8584

Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant

(3) Zhao, Rong a Masayasu, Hiroyuki b Holmgren, Arne a,b

a KAROLINSKA INSTITUTE (Sweden)

b DAIICHI SANKYO CO (Japan)

Author keywords

Inflammation; Oxidative stress; Redox regulation; Selenol; Signal transduction

Indexed keywords

EBSELEN; HYDROPEROXIDE REDUCTASE; OXIDOREDUCTASE; THIOREDOXIN; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; DRUG MECHANISM; HUMAN; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AZOLES; CATALYSIS; ENZYME ACTIVATION; HUMANS; HYDROGEN PEROXIDE; KINETICS; ORGANOSELENIUM COMPOUNDS; OXIDATION-REDUCTION; OXIDOREDUCTASES; SPECTROMETRY, FLUORESCENCE; SUBSTRATE SPECIFICITY; THIOREDOXIN REDUCTASE (NADPH);

BOVINAE; MAMMALIA;

EID: 0037172997 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.122061399 Document Type: Article

Times cited : (232)

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